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1. Full Text Contrasting forms of cocaine-evoked plasticity control components of relapse
by Pascoli, Vincent and Terrier, Jean and Espallergues, Julie and Valjent, Emmanuel and O'connor, Eoin Cornelius and Lüscher, Christian
Nature, ISSN 0028-0836, 2014, Volume 509, Issue 7501, pp. 459 - 464
Nucleus accumbens neurons serve to integrate information from cortical and limbic regions to direct behaviour. Addictive drugs are proposed to hijack this... 
AMPA RECEPTORS | ACCUMBENS-PROJECTION NEURONS | MULTIDISCIPLINARY SCIENCES | LONG-TERM DEPRESSION | DOPAMINE | MECHANISMS | INCUBATION | SYNAPTIC PLASTICITY | REWARD | ADDICTION | NUCLEUS-ACCUMBENS | Recurrence | Neural Pathways - drug effects | Neuronal Plasticity - drug effects | Male | Optogenetics | Cocaine-Related Disorders - physiopathology | Hippocampus - drug effects | Prefrontal Cortex - pathology | Receptors, Dopamine D1 - metabolism | Prefrontal Cortex - drug effects | Synapses - metabolism | Nucleus Accumbens - cytology | Dopaminergic Neurons - drug effects | Female | Receptors, AMPA - metabolism | Disease Models, Animal | Nucleus Accumbens - pathology | Synapses - drug effects | N-Methylaspartate - metabolism | Cocaine-Related Disorders - psychology | Cocaine-Related Disorders - pathology | Hippocampus - pathology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - metabolism | Hippocampus - cytology | Prefrontal Cortex - cytology | Drug-Seeking Behavior - drug effects | Cocaine - pharmacology | Animals | Mice | Nucleus Accumbens - drug effects | Nucleus accumbens | Neuroplasticity | Physiological aspects | Cocaine | Research | Properties | Psychiatric research | Dopamine | Artificial chromosomes | Animal behavior | Neurons | Rodents | Life Sciences
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2. Full Text New medications for drug addiction hiding in glutamatergic neuroplasticity
by Kalivas, P.W and Volkow, N.D
Molecular Psychiatry, ISSN 1359-4184, 10/2011, Volume 16, Issue 10, pp. 974 - 986
The repeated use of drugs that directly or indirectly stimulate dopamine transmission carry addiction liability and produce enduring pathological changes in... 
accumbens | synaptic plasticity | relapse | prefrontal cortex | glutamate | addiction | G-PROTEIN SIGNALING-3 | COCAINE-SEEKING BEHAVIOR | PSYCHIATRY | CUE-INDUCED REINSTATEMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | EXTRACELLULAR GLUTAMATE | DOPAMINE NEURONS | NUCLEUS-ACCUMBENS CORE | IN-VIVO | NMDA-RECEPTORS | LONG-TERM POTENTIATION | Adaptation, Physiological | Behavior, Addictive - drug therapy | Nucleus Accumbens - physiopathology | Substance-Related Disorders - metabolism | Neural Pathways - drug effects | Humans | Nucleus Accumbens - metabolism | Prefrontal Cortex - physiopathology | Neuronal Plasticity - drug effects | Behavior, Addictive - metabolism | Neural Pathways - physiology | Neuronal Plasticity - physiology | Prefrontal Cortex - drug effects | Excitatory Amino Acid Agents - therapeutic use | Prefrontal Cortex - metabolism | Glutamic Acid - metabolism | Substance-Related Disorders - drug therapy | Nucleus Accumbens - drug effects | Glutamic Acid - drug effects
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3. Full Text Role of ventral subiculum in context-induced relapse to alcohol seeking after punishment-imposed abstinence
by Marchant, Nathan J and Campbell, Erin J and Whitaker, Leslie R and Harvey, Brandon K and Kaganovsky, Konstantin and Adhikary, Sweta and Hope, Bruce T and Heins, Robert C and Prisinzano, Thomas E and Vardy, Eyal and Bonci, Antonello and Bossert, Jennifer M and Shaham, Yavin
Journal of Neuroscience, ISSN 0270-6474, 03/2016, Volume 36, Issue 11, pp. 3281 - 3294
In many human alcoholics, abstinence is self-imposed because of the negative consequences of excessive alcohol use, and relapse is often triggered by exposure... 
Nucleus accumbens | Punishment | Relapse | Chemogenetics | Ventral subiculum | Alcohol | Neuroscience(all) | alcohol | LATERAL HYPOTHALAMUS | ventral subiculum | INDUCED REINSTATEMENT | relapse | NUCLEUS-ACCUMBENS DOPAMINE | COCAINE-SEEKING | BASOLATERAL AMYGDALA | HEROIN SEEKING | nucleus accumbens | DRUG-SEEKING | NEUROSCIENCES | MEMORY RETRIEVAL | punishment | GLUTAMATE RECEPTORS | DORSAL HIPPOCAMPUS | chemogenetics | Alcohol Abstinence - psychology | Recurrence | Nucleus Accumbens - metabolism | Alcohol Drinking - psychology | Conditioning, Operant - physiology | Ethanol - administration & dosage | Extinction, Psychological - drug effects | Male | Green Fluorescent Proteins - genetics | Oncogene Proteins v-fos - genetics | Self Administration | Conditioning, Operant - drug effects | Neurons - metabolism | Extinction, Psychological - physiology | Nucleus Accumbens - pathology | Diterpenes - pharmacology | Nucleus Accumbens - physiopathology | Oncogene Proteins v-fos - metabolism | Green Fluorescent Proteins - metabolism | Transduction, Genetic | Cholera Toxin - metabolism | Receptors, Opioid, kappa - metabolism | Reinforcement (Psychology) | Rats | Alcohol Drinking - physiopathology | Animals | Nucleus Accumbens - drug effects
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4. Full Text Mesolimbic dopamine signals the value of work
by Hamid, Arif A and Pettibone, Jeffrey R and Mabrouk, Omar S and Hetrick, Vaughn L and Schmidt, Robert and Vander Weele, Caitlin M and Kennedy, Robert T and Aragona, Brandon J and Berke, Joshua D
Nature Neuroscience, ISSN 1097-6256, 12/2015, Volume 19, Issue 1, pp. 117 - 126
Dopamine cell firing can encode errors in reward prediction, providing a learning signal to guide future behavior. Yet dopamine is also a key modulator of... 
PREDICTION ERRORS | INCENTIVE SALIENCE | DECISION-MAKING | NUCLEUS-ACCUMBENS DOPAMINE | REWARD-SEEKING BEHAVIOR | BASAL GANGLIA | MATCHING BEHAVIOR | NEURONS | NEUROSCIENCES | FOOD-SEEKING | STRIATUM | Nucleus Accumbens - metabolism | Rats, Long-Evans | Rats | Behavior, Animal - physiology | Male | Optogenetics | Nucleus Accumbens - physiology | Learning - physiology | Animals | Microdialysis | Motivation - physiology | Time Factors | Dopamine - physiology | Decision Making - physiology | Delay Discounting - physiology | Electrophysiological Phenomena | Reward | Dopamine - metabolism | Nucleus accumbens | Decision-making | Psychological aspects | Medical examination | Dopaminergic mechanisms | Health aspects
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5. Full Text A proposed hypothalamic–thalamic–striatal axis for the integration of energy balance, arousal, and food reward
by Kelley, Ann E and Baldo, Brian A and Pratt, Wayne E
Journal of Comparative Neurology, ISSN 0021-9967, 12/2005, Volume 493, Issue 1, pp. 72 - 85
We elaborate herein a novel theory of basal ganglia function that accounts for why palatable, energy‐dense foods retain high incentive value even when... 
muscarinic | arcuate nucleus | motivation | hypocretin | nucleus accumbens core | appetite | acetylcholine | orexin | preproenkephalin | paraventricular thalamic nucleus | nucleus accumbens shell | lateral hypothalmus | Appetite | Nucleus accumbens core | Lateral hypothalmus | Muscarinic | Nucleus accumbens shell | Motivation | Paraventricular thalamic nucleus | Arcuate nucleus | Preproenkephalin | Acetylcholine | Hypocretin | Orexin | FREELY MOVING RATS | LATERAL HYPOTHALAMUS | TONICALLY ACTIVE NEURONS | MUSCARINIC RECEPTORS | NEUROSCIENCES | HYPOCRETIN OREXIN | VIVO ACETYLCHOLINE-RELEASE | ZOOLOGY | CHOLINERGIC INTERNEURONS | IN-VIVO | NUCLEUS-ACCUMBENS SHELL | VENTRAL STRIATUM | Thalamus - metabolism | Enkephalins - metabolism | Nucleus Accumbens - metabolism | Dynorphins - physiology | Nucleus Accumbens - physiology | RNA, Messenger - metabolism | Dopamine - physiology | Protein Precursors - physiology | Thalamus - physiology | Enkephalins - physiology | Energy Metabolism - physiology | Food | Acetylcholine - pharmacology | Hypothalamus - physiology | Dopamine - pharmacology | Receptors, Opioid, kappa - metabolism | Rats | Protein Precursors - metabolism | Arousal - physiology | Animals | Hypothalamus - metabolism | Models, Biological | Dynorphins - pharmacology | Narcotics - metabolism | Narcotics - pharmacology | Reward | Acetylcholine - physiology | Nucleus Accumbens - drug effects
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6. Full Text Acid-sensing ion channels contribute to synaptic transmission and inhibit cocaine-evoked plasticity
by Kreple, Collin J and Lu, Yuan and Taugher, Rebecca J and Schwager-Gutman, Andrea L and Du, Jianyang and Stump, Madeliene and Wang, Yimo and Ghobbeh, Ali and Fan, Rong and Cosme, Caitlin V and Sowers, Levi P and Welsh, Michael J and Radley, Jason J and Lalumiere, Ryan T and Wemmie, John A
Nature Neuroscience, ISSN 1097-6256, 2014, Volume 17, Issue 8, pp. 1083 - 1091
Acid-sensing ion channel 1A (ASIC1A) is abundant in the nucleus accumbens (NAc), a region known for its role in addiction. Because ASIC1A has been suggested to... 
DENDRITIC SPINES | DEPRESSION | EXOCYTOSED PROTONS | CONDITIONED PLACE PREFERENCE | NEUROTROPHIC FACTOR | KNOCKOUT MICE | HIPPOCAMPAL-NEURONS | NEUROSCIENCES | BRAIN | NUCLEUS-ACCUMBENS | Synaptic Transmission - genetics | Neuronal Plasticity - drug effects | Male | Nucleus Accumbens - physiology | Excitatory Postsynaptic Potentials - drug effects | Behavior, Animal | Neuronal Plasticity - genetics | Cocaine-Related Disorders - metabolism | Female | Synaptic Transmission - drug effects | Cocaine - antagonists & inhibitors | Excitatory Postsynaptic Potentials - genetics | Disease Models, Animal | Nucleus Accumbens - pathology | Neural Inhibition - genetics | Mice, Inbred C57BL | Rats | Mice, Transgenic | Up-Regulation - genetics | Mice, Knockout | Acid Sensing Ion Channels - deficiency | Animals | Acid Sensing Ion Channels - physiology | Mice | Nucleus Accumbens - drug effects | Neural Inhibition - drug effects | Brain research | Neural transmission | Associative learning | Ion channels | Genetic aspects | Research | Properties | ASIC1A | nucleus accumbens | cocaine | addiction
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7. Full Text Cortico-Basal Ganglia Reward Network: Microcircuitry
by Sesack, Susan R and Grace, Anthony A
Neuropsychopharmacology, ISSN 0893-133X, 01/2010, Volume 35, Issue 1, pp. 27 - 47
Many of the brain's reward systems converge on the nucleus accumbens, a region richly innervated by excitatory, inhibitory, and modulatory afferents... 
GABA | Accumbens | Dopamine | Prefrontal cortex | Glutamate | Ventral tegmental area | accumbens | CENTRAL EXTENDED AMYGDALA | PSYCHIATRY | prefrontal cortex | FAST-SPIKING INTERNEURONS | NEUROSCIENCES | RAT NUCLEUS-ACCUMBENS | TYROSINE-HYDROXYLASE IMMUNOREACTIVITY | ventral tegmental area | MIDBRAIN DOPAMINE NEURONS | MEDIAL PREFRONTAL CORTEX | PHARMACOLOGY & PHARMACY | GAMMA-AMINOBUTYRIC-ACID | MELANIN-CONCENTRATING HORMONE | BASOLATERAL AMYGDALA NEURONS | dopamine | glutamate | Humans | Ventral Tegmental Area - physiology | Basal Ganglia - anatomy & histology | Nucleus Accumbens - physiology | Basal Ganglia - physiology | Neural Pathways - physiology | Nucleus Accumbens - anatomy & histology | Neural Pathways - anatomy & histology | Animals | Cerebral Cortex - physiology | Models, Neurological | Reward | Cerebral Cortex - anatomy & histology | Ventral Tegmental Area - anatomy & histology | Neuropsychopharmacology Reviews
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