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Anaesthesia and intensive care, ISSN 0310-057X, 06/2005, Volume 33, Issue 3, pp. 311 - 322
The clinical utility of most analgesic drugs is altered in the presence of patients with impaired renal or hepatic function not simply because of altered... 
Analgesia: renal failure, renal function, hepatic failure, hepatic function, review | Acute pain | Anesthesiology | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Kidney Failure, Chronic - physiopathology | Analgesics - therapeutic use | Pain - drug therapy | Humans | Half-Life | Biological Availability | Metabolic Clearance Rate | Analgesics - pharmacokinetics | Liver Diseases - physiopathology | Liver Diseases - metabolism | Contraindications | Kidney Failure, Chronic - metabolism | Methadone, pharmacokinetics | Anti-Inflammatory Agents, Non-Steroidal, adverse effects | Piperidines, pharmacokinetics | Hydrocodone, pharmacokinetics | Fentanyl, pharmacokinetics | Pain, complications | Buprenorphine, pharmacokinetics | Hydrocodone, administration and dosage | Carbamazepine, pharmacokinetics | Acute Disease | Ketamine, pharmacokinetics | Sufentanil, pharmacokinetics | Propoxyphene, pharmacokinetics | Acetaminophen, adverse effects | Clonidine, administration and dosage | Morphine, administration and dosage | Oxycodone, administration and dosage | Propoxyphene, administration and dosage | Hydromorphone, administration and dosage | Methadone, administration and dosage | Alfentanil, pharmacokinetics | Buprenorphine, administration and dosage | Codeine, pharmacokinetics | Meperidine, pharmacokinetics | Sufentanil, administration and dosage | Anesthetics, Local, therapeutic use | Codeine, administration and dosage | Mexiletine, pharmacokinetics | Mexiletine, administration and dosage | Anti-Inflammatory Agents, Non-Steroidal, therapeutic use | Liver Failure, complications | Alfentanil, administration and dosage | Piperidines, administration and dosage | Pain, drug therapy | Ketamine, administration and dosage | Fentanyl, administration and dosage | Carbamazepine, administration and dosage | Hydromorphone, pharmacokinetics | Ketorolac, pharmacokinetics | Analgesics, Opioid, therapeutic use | Ketorolac, administration and dosage | Tramadol, administration and dosage | Morphine, pharmacokinetics | Valproic Acid, pharmacokinetics | Acetaminophen, administration and dosage | Valproic Acid, administration and dosage | Tramadol, pharmacokinetics | Acetic Acids | Kidney Failure, complications | Antidepressive Agents, Tricyclic, therapeutic use | Meperidine, administration and dosage | Clonidine, pharmacokinetics | Analgesics, Non-Narcotic, therapeutic use | Oxycodone, pharmacokinetics | Valproic Acid, adverse effects | Index Medicus
Journal Article
Toxicology and applied pharmacology, ISSN 0041-008X, 2004, Volume 201, Issue 3, pp. 226 - 294
Experience with dose response and mechanisms of toxicity has shown that multiple mechanisms may exist for a single agent along the continuum of the full... 
Mechanisms of toxicity | Dose response | Formaldehyde | Zinc | Progesterone/hydroxyflutamide | Propylene oxide | Dose-dependent transitions | Peroxisome proliferator-activated receptor | Acetaminophen | Vinylidene chloride | Butadiene, ethylene glycol | Methylene chloride | Vinyl acetate | Vinyl chloride | Manganese | Progesterone/ hydroxyflutamide | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Analgesics, Non-Narcotic - pharmacokinetics | Progesterone - administration & dosage | Humans | Acetaminophen - administration & dosage | Epoxy Compounds - pharmacokinetics | Dichloroethylenes - toxicity | Manganese - pharmacokinetics | Methylene Chloride - administration & dosage | Analgesics, Non-Narcotic - toxicity | Manganese - administration & dosage | Dichloroethylenes - pharmacokinetics | Dichloroethylenes - administration & dosage | Formaldehyde - toxicity | Androgen Antagonists - toxicity | Ethylene Glycol - toxicity | Butadienes - toxicity | Androgen Antagonists - pharmacokinetics | Progesterone - pharmacokinetics | Oxidation-Reduction | Acetaminophen - toxicity | Vinyl Compounds - administration & dosage | Zinc - toxicity | Androgen Antagonists - administration & dosage | Flutamide - administration & dosage | Vinyl Compounds - toxicity | Zinc - administration & dosage | Peroxisome Proliferator-Activated Receptors - physiology | Drug-Related Side Effects and Adverse Reactions - chemically induced | Flutamide - toxicity | Drug-Related Side Effects and Adverse Reactions - metabolism | Vinyl Compounds - pharmacokinetics | Dose-Response Relationship, Drug | Methylene Chloride - toxicity | Zinc - pharmacokinetics | Epoxy Compounds - administration & dosage | Formaldehyde - administration & dosage | Ethylene Glycol - administration & dosage | Formaldehyde - pharmacokinetics | Ethylene Glycol - pharmacokinetics | Butadienes - pharmacokinetics | Flutamide - analogs & derivatives | Analgesics, Non-Narcotic - administration & dosage | Epoxy Compounds - toxicity | Animals | Butadienes - administration & dosage | Progesterone - toxicity | Methylene Chloride - pharmacokinetics | Acetaminophen - pharmacokinetics | Flutamide - pharmacokinetics | Manganese Poisoning - metabolism | Index Medicus
Journal Article
Cochrane library, ISSN 1465-1858, 01/2009, Volume 2019, Issue 5, pp. CD001547 - CD001547
Journal Article