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Journal Article
PloS one, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, pp. e0137776 - e0137776
...(+) T cell fate remains unclear. It has been previously established in various tissues that acetyl CoA carboxylase 2 (ACC2... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fatty Acids - immunology | Lymphocytic choriomeningitis virus - immunology | Mitochondria - enzymology | Carnitine O-Palmitoyltransferase - genetics | Mitochondria - immunology | Listeria monocytogenes - immunology | Lymphocytic Choriomeningitis - immunology | Acetyl-CoA Carboxylase - genetics | Mitochondria - genetics | Fatty Acids - genetics | Carnitine O-Palmitoyltransferase - metabolism | Listeriosis - enzymology | Listeriosis - immunology | Fatty Acids - metabolism | Lymphocytic Choriomeningitis - genetics | Carnitine O-Palmitoyltransferase - immunology | Listeriosis - genetics | Acetyl-CoA Carboxylase - immunology | Mice, Transgenic | CD8-Positive T-Lymphocytes - enzymology | Animals | Lymphocytic Choriomeningitis - enzymology | Mice | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Energy metabolism | Phosphorylation | CD8 antigen | Viruses | Infections | Lymphocytes T | Kinases | Immunity | Experiments | Mitochondria | Immunology | Listeria | Cell fate | Lymphocytes | Oxidation | Pathogens | Antigens | Immunological memory | Memory cells | T cell receptors | Metabolism | Palmitoyltransferase | Fatty acids | Carbon | Carnitine palmitoyltransferase | Carnitine | Medicine | Pathology | Metabolic pathways | Laboratory animals | Index Medicus
Journal Article
Journal Article
Nature medicine, ISSN 1546-170X, 09/2016, Volume 22, Issue 10, pp. 1108 - 1119
.... This process is controlled by the rate-limiting enzyme acetyl-CoA carboxylase (ACC), an attractive but traditionally intractable drug target... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Lung Neoplasms - drug therapy | Proto-Oncogene Proteins p21(ras) - genetics | Allosteric Regulation | Humans | Lung Neoplasms - metabolism | Molecular Targeted Therapy | Tumor Suppressor Protein p53 - genetics | Acetyltransferases - antagonists & inhibitors | Lipid Metabolism - genetics | Pyrimidinones - pharmacology | Acetyl-CoA Carboxylase - antagonists & inhibitors | Lung Neoplasms - genetics | Cell Proliferation - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Thiophenes - pharmacology | Mice, Knockout | Xenograft Model Antitumor Assays | Animals | Lipid Metabolism - drug effects | Cell Proliferation - drug effects | Mice | Carcinoma, Non-Small-Cell Lung - drug therapy | Fatty Acids - biosynthesis | Synthesis | Growth | Cancer cells | Genetic aspects | Models | Research | Lung cancer, Non-small cell | Fatty acids | Carboxylases | Animal models | p53 Protein | Xenotransplantation | Lung cancer | Non-small cell lung carcinoma | Pharmacology | LKB1 protein | Allosteric properties | Liability | Acetyl-CoA carboxylase | Lungs | Xenografts | Carboplatin | Genetic engineering | Inhibition | Dimerization | Viability | Cancer | Tumors | Index Medicus
Journal Article
Journal Article