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Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 10/2013, Volume 23, Issue 20, pp. 5694 - 5698
AAC(6a2)-Ib is an important aminoglycoside resistance enzyme to target with enzymatic inhibitors. An in silico screening approach was used to identify... 
Acetylation
Journal Article
Cancer Science, ISSN 1347-9032, 02/2011, Volume 102, Issue 2, pp. 343 - 350
Histone deacetylase (HDAC) is an attractive target for cancer therapy because it plays a key role in gene expression and carcinogenesis.... 
Acetylation
Journal Article
Methods in Cell Biology, ISSN 0091-679X, 01/2013, Volume 115, pp. 247 - 267
Microtubules play highly diverse and essential roles in every eukaryotic cell. While built from conserved dimers of I-- and I2-tubulin, microtubules can be... 
Acetylation
Journal Article
Brain Research, ISSN 0006-8993, 10/2010, Volume 1354, pp. 172 - 178
Although the pathophysiological processes involved in dopamine (DA) neuron degeneration in Parkinson's disease (PD) are not completely known, apoptotic cell... 
Acetylation
Journal Article
Journal of Molecular Medicine (Berlin, Germany), ISSN 0946-2716, 01/2011, Volume 89, Issue 1, pp. 29 - 41
Chemokines play important roles in asthma. Prostaglandin I sub(2) (PGI sub(2)) analogue is recently suggested as a candidate for treating asthma. However, the... 
Acetylation
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 01/2011, Volume 670, pp. 263 - 274
Recent years have witnessed an explosion of research on the role of epigenetic modifications, such as DNA methylation and histone protein acetylation and... 
Acetylation
Journal Article
Letters in Drug Design & Discovery, ISSN 1570-1808, 10/2013, Volume 10, Issue 8, pp. 738 - 740
The solid-phase synthesis of di-N-acetyl-I2-chitobiosyl N-glycoaminooxazoline 2 was studied. The synthesis was gone along using the N-benzyloxycarbonyl (Cbz)... 
Acetylation
Journal Article
PLoS ONE, 12/2013, Volume 8, Issue 12
Sirtuins, class III histone deacetylases, are proteins homologous to the yeast protein Sir2p. Mammalian Sirt1 has been shown to be involved in energy... 
Acetylation
Journal Article
PLoS ONE, 12/2013, Volume 8, Issue 12
Expression of the estrogen receptor- alpha (ER alpha ) gene, ESR1, is a clinical biomarker used to predict therapeutic outcome of breast cancer. Hence, there... 
Acetylation
Journal Article
PLoS ONE, 11/2013, Volume 8, Issue 11
Background Mesenchymal stem cells (MSCs) have been considered as ideal cells for the treatment of a variety of diseases. However, aging and spontaneous... 
Acetylation
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
STAT5 proteins are adaptor proteins for histone acetylation enzymes. Histone acetylation at promoter and enhancer chromosomal regions opens the chromatin and... 
Acetylation
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Objective Islet-1 is an important transcription factor for cardiac development through mediating extensive interactions between DNA and proteins. The present... 
Acetylation
Journal Article
PLoS ONE, 10/2013, Volume 8, Issue 10
Post-translational modification (PTM) of RNA binding proteins (RBPs) play a very important role in determining their binding to cognate RNAs and therefore... 
Acetylation
Journal Article
PLoS ONE, 09/2013, Volume 8, Issue 9
Resveratrol, a natural polyphenol compound, has broad effects on critical events, including inflammation, oxidation, cancer and aging. However, the function... 
Acetylation
Journal Article
PLoS ONE, 09/2013, Volume 8, Issue 9
Chromatin is a highly compact and dynamic nuclear structure that consists of DNA and associated proteins. The main organizational unit is the nucleosome, which... 
Acetylation
Journal Article
Journal of Triticeae Crops, ISSN 1009-1041, 09/2013, Volume 33, Issue 5, pp. 869 - 874
Histone acetyltransferase (HATs) plays an important role in modification of the structure of chromosomes and regulation of gene expression. The main function... 
Acetylation
Journal Article
PLoS ONE, 08/2013, Volume 8, Issue 8
Drug resistance is a major obstacle for the successful treatment of many malignancies, including neuroblastoma, the most common extracranial solid tumor in... 
Acetylation
Journal Article
PLoS ONE, 08/2013, Volume 8, Issue 8
Psychiatric diseases, including schizophrenia, bipolar disorder and major depression, are projected to lead global disease burden within the next decade.... 
Acetylation
Journal Article
PLoS ONE, 07/2013, Volume 8, Issue 7
LIM-homeodomain 3 (LHX3) is a transcription factor required for mammalian pituitary gland and nervous system development. Human patients and animal models with... 
Acetylation
Journal Article
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