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Neuropharmacology, ISSN 0028-3908, 09/2016, Volume 108, pp. 220 - 228
Scopolamine is a high affinity muscarinic antagonist that is used for the prevention of post-operative nausea and vomiting. 5-HT receptor antagonists are used... 
Scopolamine | Muscarinic | Amygdala | Memory | Depression | Binding site | Cognition | 5-HT3 | Ligand docking | Anxiety | Antagonist | Cys-loop | Hippocampus | 5-HT | RADIOLIGAND | ONDANSETRON | NEUROSCIENCES | STRUCTURAL DETERMINANTS | BIOAVAILABILITY | ACETYLCHOLINE-RECEPTORS | LIGANDS | PHARMACOLOGY | PHARMACOLOGY & PHARMACY | SEROTONIN | BINDING
Journal Article
Lancet, The, ISSN 0140-6736, 2017, Volume 389, Issue 10082, pp. 1919 - 1929
Journal Article
Journal Article
The Journal of Physiology, ISSN 0022-3751, 11/2011, Volume 589, Issue 21, pp. 5109 - 5123
Non‐Technical Summary  Cardiovascular disease and high blood pressure (hypertension) are frequent in the human population. Amiloride is commonly given as a... 
INACTIVATION | SELECTIVE INHIBITOR | ZONIPORIDE | PHYSIOLOGY | NERVE-TERMINALS | NEUROTRANSMISSION | AMILORIDE | SODIUM-CHANNEL | EXPRESSION | NEUROSCIENCES | BLOCKER | MODULATION | Xenopus | Nerve Tissue Proteins - deficiency | Amiloride - analogs & derivatives | Guanidines - pharmacology | Sodium Channels - physiology | Brain - physiology | Nicotine - pharmacology | Neurons - physiology | Oocytes - drug effects | Synaptic Transmission - drug effects | Neurons - drug effects | Nicotinic Agonists - pharmacology | Sodium Channels - deficiency | Sodium-Hydrogen Exchangers - antagonists & inhibitors | Pyrazoles - pharmacology | Cell Line | Nerve Tissue Proteins - antagonists & inhibitors | Nerve Tissue Proteins - physiology | Acid Sensing Ion Channels | Sodium-Hydrogen Exchangers - physiology | Mice, Inbred C57BL | Sodium Channel Blockers - pharmacology | Nerve Tissue Proteins - genetics | Mice, Knockout | Brain - drug effects | Animals | Oocytes - physiology | Receptors, Nicotinic - physiology | Amiloride - pharmacology | Mice | Sodium Channels - genetics | In Vitro Techniques | Hypertension | Cardiovascular disease | Potassium | Investigations | Drugs | Brain | Brain slice preparation | Nervous system | Antagonists | Oocytes | Potassium channels (calcium-gated) | Antagonism | Amiloride | Synaptic transmission | Habenula | Cardiorespiratory | Medications | Blood pressure | Communication | Peripheral nervous system | Sodium channels | gamma -Aminobutyric acid receptors | Cross-reactivity | Excitability | Acidity | Acetylcholine receptors (nicotinic) | Glutamatergic transmission | Blood diseases | Cardiovascular diseases | Animal subjects | Neuroscience
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 10/2012, Volume 22, Issue 19, pp. 6039 - 6047
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 01/2015, Volume 746, pp. 308 - 316
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 08/2014, Volume 57, Issue 15, pp. 6739 - 6750
Journal Article
Journal Article
ChemMedChem, ISSN 1860-7179, 08/2017, Volume 12, Issue 15, pp. 1156 - 1156
The front cover picture shows a novel potent muscarinic M3 receptor antagonist (R)‐3‐[2‐hydroxy‐2,2‐di(thiophen‐2‐yl)acetoxy]‐1,1‐dimethylpyrrolidinium bromide... 
ammonium salts | antagonists | structure–activity relationships | stability | nitrogen heterocycles | Plasma | Recombination | Stability | Acetylcholine receptors (muscarinic) | Structural stability | Lung diseases | Obstructive lung disease | Bronchus | Chronic obstructive pulmonary disease | Blood plasma | Plasmas (physics)
Journal Article
Journal of Labelled Compounds and Radiopharmaceuticals, ISSN 0362-4803, 07/2019, Volume 62, Issue 9, pp. 604 - 607
A useful synthesis of (R)‐[N‐methyl‐3H]quinuclidinyl benzilate methiodide is described with the product characterized by thin‐layer chromatography (TLC),... 
tritium | muscarinic receptor | quinuclidinyl benzilate methiodide | tritium NMR | CHEMISTRY, ANALYTICAL | CHEMISTRY, MEDICINAL | RAT | QUINUCLIDINYL BENZILATE | BIOCHEMICAL RESEARCH METHODS | BINDING | Mass spectrometry | High performance liquid chromatography
Journal Article
Journal Article