X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (13116) 13116
Publication (1336) 1336
Newsletter (158) 158
Book Review (60) 60
Book Chapter (34) 34
Magazine Article (11) 11
Dissertation (6) 6
Conference Proceeding (5) 5
Data Set (2) 2
Book / eBook (1) 1
Paper (1) 1
Trade Publication Article (1) 1
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (7066) 7066
humans (6238) 6238
index medicus (5962) 5962
acetylcysteine - pharmacology (5913) 5913
oxidative stress (4455) 4455
male (4114) 4114
n-acetylcysteine (3874) 3874
acetylcysteine (3553) 3553
rats (3494) 3494
reactive oxygen species - metabolism (2684) 2684
mice (2600) 2600
biochemistry & molecular biology (2425) 2425
apoptosis (2379) 2379
antioxidants (2148) 2148
female (2052) 2052
glutathione (1998) 1998
antioxidants - pharmacology (1875) 1875
pharmacology & pharmacy (1724) 1724
glutathione - metabolism (1663) 1663
oxidative stress - drug effects (1582) 1582
apoptosis - drug effects (1536) 1536
toxicology (1533) 1533
reactive oxygen species (1490) 1490
cells, cultured (1460) 1460
cell biology (1429) 1429
acetylcysteine - analogs & derivatives (1409) 1409
cysteine (1200) 1200
activation (1193) 1193
cell line (1117) 1117
free radical scavengers - pharmacology (1111) 1111
dose-response relationship, drug (1109) 1109
acetylcysteine - therapeutic use (1105) 1105
expression (1085) 1085
analysis (1080) 1080
rats, sprague-dawley (1060) 1060
cell line, tumor (1036) 1036
proteins (1036) 1036
rats, wistar (974) 974
cell survival - drug effects (952) 952
metabolism (942) 942
time factors (914) 914
acetylcysteine - metabolism (890) 890
cells (882) 882
toxicity (878) 878
oncology (855) 855
neurosciences (847) 847
research (844) 844
adult (841) 841
in-vitro (818) 818
cancer (815) 815
inhibition (787) 787
physiological aspects (774) 774
inflammation (761) 761
oxidation-reduction (759) 759
gene expression (758) 758
disease models, animal (756) 756
endocrinology & metabolism (749) 749
signal transduction (746) 746
phosphorylation (736) 736
article (718) 718
liver (718) 718
research article (708) 708
mitochondria (693) 693
rodents (685) 685
middle aged (678) 678
acetylcysteine - administration & dosage (676) 676
medicine (661) 661
health aspects (640) 640
liver - metabolism (638) 638
physiology (638) 638
antioxidant (636) 636
lipid-peroxidation (630) 630
hydrogen-peroxide (605) 605
multidisciplinary sciences (598) 598
liver - drug effects (586) 586
superoxide (582) 582
free radicals (573) 573
blotting, western (556) 556
enzymes (555) 555
enzyme inhibitors - pharmacology (535) 535
gene-expression (535) 535
signal transduction - drug effects (528) 528
immunology (524) 524
mechanisms (524) 524
mitochondria - metabolism (511) 511
mice, inbred c57bl (509) 509
ros (507) 507
medicine, research & experimental (498) 498
nitric-oxide (494) 494
cell death (477) 477
cystine (475) 475
cytotoxicity (474) 474
science (469) 469
nf-kappa b - metabolism (468) 468
antioxidants - metabolism (463) 463
in-vivo (463) 463
cysteine proteinase inhibitors - pharmacology (462) 462
mitochondria - drug effects (455) 455
cell proliferation - drug effects (449) 449
antioxidants - therapeutic use (445) 445
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (13087) 13087
Chinese (86) 86
Russian (41) 41
German (24) 24
Japanese (16) 16
Italian (15) 15
Polish (12) 12
French (11) 11
Spanish (4) 4
Danish (2) 2
Dutch (2) 2
Hungarian (2) 2
Korean (2) 2
Turkish (2) 2
Ukrainian (2) 2
Arabic (1) 1
Croatian (1) 1
Finnish (1) 1
Portuguese (1) 1
Romanian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2010, Volume 12, Issue 9, pp. 863 - 875
Accumulation of unwanted/misfolded proteins in aggregates has been observed in airways of patients with cystic fibrosis (CF), a life-threatening genetic... 
APOPTOSIS | UNFOLDED PROTEIN RESPONSE | BECLIN 1 | DOWN-REGULATION | ENDOPLASMIC-RETICULUM | MICE | GENE-TRANSFER | TISSUE TRANSGLUTAMINASE | NEURODEGENERATIVE DISEASES | CELL-DEATH | CELL BIOLOGY | Reactive Oxygen Species - metabolism | Respiratory Mucosa - drug effects | Sequestosome-1 Protein | Humans | Transglutaminases - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Autophagy - drug effects | Young Adult | Cystamine - therapeutic use | Inflammation - metabolism | Autophagy - genetics | Nasal Polyps - metabolism | Mice, Inbred CFTR | Respiratory Mucosa - cytology | Cystic Fibrosis - metabolism | Membrane Proteins - genetics | Mice, Transgenic | Protein Transport - genetics | Apoptosis Regulatory Proteins - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Models, Biological | Cystic Fibrosis - genetics | Transglutaminases - metabolism | Adolescent | Cystic Fibrosis Transmembrane Conductance Regulator - genetics | Mice | GTP-Binding Proteins | Cystic Fibrosis - drug therapy | Protein Binding - physiology | Microtubule-Associated Proteins - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Salicylates - pharmacology | Epithelial Sodium Channels - genetics | Apoptosis Regulatory Proteins - genetics | Adult | Cystamine - pharmacology | Membrane Proteins - metabolism | Acetylcysteine - therapeutic use | Beclin-1 | Cystic Fibrosis Transmembrane Conductance Regulator - antagonists & inhibitors | Cell Line | Small Ubiquitin-Related Modifier Proteins - metabolism | Heat-Shock Proteins - metabolism | Cystic Fibrosis Transmembrane Conductance Regulator - metabolism | Antioxidants - pharmacology | Mice, Inbred Strains | Nasal Polyps - drug therapy | Antioxidants - therapeutic use | Animals | Acetylcysteine - pharmacology | Adaptor Proteins, Signal Transducing - genetics | Respiratory Mucosa - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Organometallic Compounds - pharmacology | Complications and side effects | Active oxygen | Gene mutations | Lung diseases | Physiological aspects | Cystic fibrosis | Genetic aspects | Research | Health aspects | Risk factors
Journal Article
Molecular Carcinogenesis, ISSN 0899-1987, 02/2014, Volume 53, Issue 2, pp. 85 - 97
As a link between inflammation and cancer has been reported in many studies, we established an in vitro model of prostatic inflammation to investigate the loss... 
androgen | loss of p53 | inflammation | DNA damage | ROS | prostate | NFkB | Loss of p53 | Androgen | Inflammation | Prostate | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLUTATHIONE-PEROXIDASE | CANCER | ONCOLOGY | GENES | NKX3.1 | LINK | EXPRESSION | Proto-Oncogene Proteins c-mdm2 - genetics | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Antioxidants - metabolism | Homeodomain Proteins - metabolism | Humans | Transcriptional Activation - drug effects | Tumor Necrosis Factor-alpha - genetics | Apoptosis - genetics | Male | NF-kappa B - metabolism | Interleukin-1beta - genetics | Prostatitis - metabolism | Inflammation - metabolism | Matrix Metalloproteinase 9 - metabolism | Phosphorylation - genetics | Acetylcysteine - analogs & derivatives | Interleukin-1beta - metabolism | Matrix Metalloproteinase 9 - genetics | U937 Cells | Prostate-Specific Antigen - metabolism | Phosphorylation - drug effects | Interleukin-6 - metabolism | Prostate-Specific Antigen - genetics | Glutathione Peroxidase - metabolism | Lysine - analogs & derivatives | Interleukin-6 - genetics | Down-Regulation - genetics | Glutathione Peroxidase - genetics | Prostatitis - drug therapy | Androgens - genetics | Macrophages - metabolism | Receptors, Androgen - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Androgens - metabolism | Tumor Necrosis Factor-alpha - metabolism | Prostatic Neoplasms - metabolism | Receptors, Androgen - metabolism | I-kappa B Proteins - metabolism | I-kappa B Proteins - genetics | Prostatitis - pathology | Tumor Suppressor Protein p53 - genetics | Cell Differentiation - genetics | Prostatic Neoplasms - genetics | Inflammation Mediators - metabolism | Proto-Oncogene Proteins c-mdm2 - metabolism | Prostatic Neoplasms - pathology | Kallikreins - genetics | Tumor Suppressor Protein p53 - metabolism | Antioxidants - pharmacology | Transcription Factors - genetics | Down-Regulation - drug effects | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Up-Regulation - drug effects | Lysine - pharmacology | NF-kappa B - genetics | Cell Differentiation - drug effects | Acetylcysteine - pharmacology | Inflammation - genetics | Macrophages - drug effects | Kallikreins - metabolism | Ubiquitin | Analysis | Kallikrein | Hormones, Sex | Tumor proteins | Mitogens | Androgens | Cytokines | Molecular biology | Gene expression | Prostate cancer | Index Medicus
Journal Article
Cell Metabolism, ISSN 1550-4131, 2009, Volume 10, Issue 4, pp. 260 - 272
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2012, Volume 26, Issue 7, pp. 1085 - 1094
Highlight ► N -acetylcysteine protects against LPS-induced inhibition of amyloid beta efflux across the blood–brain barrier. 
Psychiatry | Allergy and Immunology | Oxidative stress | Amyloid beta | Alzheimer’s disease | Lipopolysaccharide | Pgp | Neuroinflammation | LRP-1 | N-acetylcysteine | Alzheimer's disease | P-GLYCOPROTEIN FUNCTION | METABOLIC SYNDROME | PSYCHIATRY | ALZHEIMERS-DISEASE | MICROVASCULAR ENDOTHELIAL-CELLS | COGNITIVE IMPAIRMENT | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | NEUROSCIENCES | SYSTEMIC INFLAMMATION | AMYLOID-BETA-PEPTIDE | ACETYL-L-CYSTEINE | Inflammation - chemically induced | Chemokines - blood | Glutathione - metabolism | Antioxidants - metabolism | Cerebral Cortex - pathology | Acetylcysteine - metabolism | Male | Protein Carbonylation - drug effects | Cerebral Cortex - metabolism | Lipopolysaccharides | Inflammation - metabolism | Amyloid beta-Peptides - metabolism | Calcium Channel Blockers - metabolism | Cytokines - blood | Tumor Suppressor Proteins - metabolism | Cytokines - metabolism | Receptors, LDL - metabolism | Hippocampus - pathology | Antioxidants - pharmacology | Blood-Brain Barrier - drug effects | Blood-Brain Barrier - metabolism | Hippocampus - metabolism | alpha-Macroglobulins - metabolism | Algorithms | Animals | Acetylcysteine - pharmacology | Chemokines - metabolism | Mice | Oxidative Stress - drug effects | Verapamil - metabolism | Inflammation - physiopathology | Serum Albumin - metabolism | Antioxidants | Acetylcysteine | Mitogens | Low density lipoproteins | neuroinflammation | lipopolysaccharide | oxidative stress
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 08/2010, Volume 30, Issue 8, pp. 1553 - 1561
OBJECTIVE—To investigate the potential role of nuclear factor–erythroid 2–related factor 2 (Nrf2) in neovascularization with a murine surgical model of... 
endothelial cells | inflammation | peripheral vascular disease | neovascularization | ischemia | CELLS | OXIDATIVE DAMAGE | ANGIOGENESIS | BONE-MARROW | LUNG INJURY | INDUCTION | IN-VITRO | ARYL-HYDROCARBON RECEPTOR | SIGNALING PATHWAY | HEMATOLOGY | ENDOTHELIAL GROWTH-FACTOR | Tumor Necrosis Factor-alpha - metabolism | Neovascularization, Physiologic - drug effects | Heme Oxygenase-1 - metabolism | Hindlimb | Oxidative Stress | Glutathione - metabolism | Peroxiredoxins - metabolism | Male | Muscle, Skeletal - metabolism | Ischemia - genetics | RNA, Messenger - metabolism | Inflammation - metabolism | Ligation | Time Factors | Muscle, Skeletal - drug effects | Inflammation Mediators - metabolism | Superoxides - metabolism | NF-E2-Related Factor 2 - genetics | Thioredoxins - metabolism | Chemokine CCL2 - metabolism | Membrane Proteins - metabolism | Capillaries - metabolism | Disease Models, Animal | Muscle, Skeletal - blood supply | Capillaries - physiopathology | Endothelial Cells - metabolism | Neovascularization, Physiologic - genetics | Mice, Inbred C57BL | Ischemia - metabolism | Antioxidants - pharmacology | Ischemia - physiopathology | Laser-Doppler Flowmetry | NF-E2-Related Factor 2 - deficiency | Cell Adhesion Molecules - metabolism | Regional Blood Flow | Mice, Knockout | Animals | NF-E2-Related Factor 2 - metabolism | Acetylcysteine - pharmacology | Cyclooxygenase 2 - metabolism | Inflammation - genetics | Mice | Angiogenic Proteins - metabolism | Femoral Artery - surgery | Inflammation - physiopathology
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23367
Background: Recent studies have demonstrated that activation of autophagy increases the lifespan of organisms from yeast to flies. In contrast to the lifespan... 
LIFE-SPAN EXTENSION | PATHOGENESIS | OXIDATIVE STRESS | INHIBITION | DISRUPTION | MULTIDISCIPLINARY SCIENCES | GENES | RESISTANCE | MITOCHONDRIAL DYSFUNCTION | SUPPRESSION | CELL BIOLOGY | Reactive Oxygen Species - metabolism | TOR Serine-Threonine Kinases - metabolism | Sequestosome-1 Protein | Humans | Cellular Senescence - drug effects | Male | Autophagy - physiology | Phosphoproteins - metabolism | Fibroblasts - ultrastructure | Tumor Suppressor Protein p53 - genetics | Small Ubiquitin-Related Modifier Proteins - genetics | Toluene - analogs & derivatives | RNA Interference | Time Factors | beta-Galactosidase - metabolism | Autophagy - genetics | Toluene - pharmacology | Child | Fibroblasts - metabolism | Autophagy-Related Protein 12 | Cellular Senescence - genetics | Ubiquitin-Activating Enzymes - genetics | Lysosome-Associated Membrane Glycoproteins - metabolism | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Benzothiazoles - pharmacology | Small Ubiquitin-Related Modifier Proteins - metabolism | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Cellular Senescence - physiology | Signal Transduction - genetics | Microscopy, Electron | Ubiquitin-Activating Enzymes - metabolism | Blotting, Western | Autophagy-Related Protein 7 | Acetylcysteine - pharmacology | Lysosome-Associated Membrane Glycoproteins - genetics | Signal Transduction - physiology | Fibroblasts - cytology | Primary Cell Culture | Adaptor Proteins, Signal Transducing - metabolism | Lysosomal-Associated Membrane Protein 2 | Acetylcysteine | Tumor proteins | Genetic translation | Cells | Protein binding | TOR protein | Huntingtons disease | Senescence | Phosphorylation | Yeast | p53 Protein | Impairment | Galactosidase | Viruses | Homology | Activation | Biochemistry | Autophagy | Fibroblasts | Aging | Cytokines | LAMP-2 protein | Translation initiation | Rapamycin | Ribosomal protein S6 | siRNA | Mammals | Membrane proteins | Medicine | Life span | Morphology | Initiation factor eIF-4E | Molecular biology | Alzheimers disease | Phagocytosis | Apoptosis
Journal Article