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Journal of Neurochemistry, ISSN 0022-3042, 07/2005, Volume 94, Issue 2, pp. 299 - 306
Previous studies have shown that N ‐methyl‐ d ‐aspartate (NMDA) receptor activation results in production of reactive oxygen species (ROS) and activation of... 
reactive | learning and memory | oxygen species | superoxide | long‐term potentiation | Learning and memory | Superoxide | Oxygen species | Reactive | Long-term potentiation | STIMULATION | PHOSPHORYLATION | CHRONIC GRANULOMATOUS-DISEASE | PROTEIN-KINASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CASCADE | NEUROSCIENCES | NITRIC-OXIDE | SMOOTH-MUSCLE-CELLS | SUPEROXIDE PRODUCTION | long-term potentiation | Catalase - pharmacology | Free Radical Scavengers - pharmacology | Excitatory Postsynaptic Potentials - radiation effects | Reactive Oxygen Species - metabolism | NADPH Oxidases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Excitatory Postsynaptic Potentials - drug effects | Metalloporphyrins - pharmacology | Organoselenium Compounds - pharmacology | Patch-Clamp Techniques - methods | Dopamine Agonists | N-Methylaspartate - pharmacology | Excitatory Postsynaptic Potentials - physiology | Drug Interactions | Acetylcysteine - analogs & derivatives | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Hippocampus - enzymology | Phosphorylation - drug effects | Neurons - drug effects | Extracellular Signal-Regulated MAP Kinases - classification | NG-Nitroarginine Methyl Ester - pharmacology | Lysine - analogs & derivatives | Blotting, Western - methods | Superoxide Dismutase - pharmacology | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Imidazolines - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Azoles - pharmacology | Enzyme Activation - drug effects | Hippocampus - cytology | Receptors, N-Methyl-D-Aspartate - physiology | Animals | Lysine - pharmacology | Acetylcysteine - pharmacology | Mice | In Vitro Techniques | Enzyme Activation - physiology | Catecholamines - pharmacology | Brain | Neurology | Enzymes | Acids | Index Medicus
Journal Article
Oncology Reports, ISSN 1021-335X, 03/2017, Volume 37, Issue 3, pp. 1907 - 1913
Brain tumors are highly aggressive, characterized by the secretion of high levels of matrix metalloproteinase (MMP)-2 and MMP-9 that degrade the extracellular... 
Inhibitors | Matrix metalloproteinases | Cytokines | Glioblastoma T-98G | Inducers | VITAMIN-C | GLIOMA-CELLS | inhibitors | CANCER-RELATED INFLAMMATION | glioblastoma T-98G | N-ACETYLCYSTEINE | LINES | GREEN TEA | BRAIN-TUMOR | IN-VITRO | ONCOLOGY | inducers | GROWTH | cytokines | matrix metalloproteinases | TUMOR MICROENVIRONMENT | Enzyme Activators - pharmacology | Gene Expression Regulation, Enzymologic - drug effects | Glioblastoma - enzymology | Interleukin-1beta - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Humans | Carcinogens - pharmacology | Cattle | Matrix Metalloproteinase 9 - secretion | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Tumor Cells, Cultured | Catechin - pharmacology | Tretinoin - pharmacology | Antioxidants - pharmacology | Matrix Metalloproteinase Inhibitors - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Glioblastoma - pathology | Lipopolysaccharides - pharmacology | Doxycycline - pharmacology | Matrix Metalloproteinase 2 - secretion | Anti-Bacterial Agents - pharmacology | Catechin - analogs & derivatives | Glioblastoma - drug therapy | Cytokines - pharmacology | Enzymes | Care and treatment | Proteases | Development and progression | Genetic aspects | Regulation | Health aspects | Glioblastoma multiforme | Angiogenesis | Acids | Collagen | Brain cancer | Penicillin | Tumor necrosis factor-TNF | Nervous system | Metastasis | Cancer therapies | Tumors | Apoptosis | Index Medicus
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2009, Volume 296, Issue 2, pp. 470 - 479
Bacterial endotoxin lipopolysaccharide (LPS) is responsible for the multiorgan dysfunction that characterizes septic shock and is causal in the myocardial... 
Green fluorescent protein- Microtubule-associated protein light chain 3 | Lipopolysaccharide | Oxidative stress | Hl-1 cardiac myocyte | TRANSCRIPTIONAL ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | HL-1 cardiac myocyte | CARDIAC MYOCYTES | NECROSIS-FACTOR-ALPHA | MYOCARDIAL DEPRESSION | PROGRAMMED CELL-DEATH | ENDOTOXEMIC RATS | SCAVENGER RECEPTOR | green fluorescent protein-microtubule-associated protein light chain 3 | SEPTIC SHOCK | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | lipopolysaccharide | NF-KAPPA-B | oxidative stress | Tumor Necrosis Factor-alpha - metabolism | Mitochondria, Heart - metabolism | Glutathione - metabolism | Mitochondria, Heart - pathology | Nitric Oxide Synthase - antagonists & inhibitors | omega-N-Methylarginine - pharmacology | Mitochondria, Heart - drug effects | Nitroprusside - pharmacology | Autophagy - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Donors - pharmacology | Cytoprotection | Animals, Newborn | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mice, Transgenic | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Sirolimus - pharmacology | Hydrogen Peroxide - metabolism | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Mice | Nitric Oxide Synthase - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Signal transduction | Bacteria | Oxidation | Biochemistry | Cytokines | Sugar | Index Medicus
Journal Article
Oncology Reports, ISSN 1021-335X, 03/2017, Volume 37, Issue 3, pp. 1842 - 1848
Acute myeloid leukemia and head and neck squamous cell carcinomas are the major causes of mortality and morbidity in Fanconi anemia (FA) patients. Matrix... 
Fanconi anemia fibroblasts | Inhibitors | Matrix metalloproteinases | Cytokines | Inducers | VITAMIN-C | inhibitors | TUMOR INVASION | STRAND BREAK REPAIR | METASTASIS | CARCINOMA CELLS | N-ACETYLCYSTEINE | GREEN TEA | IN-VITRO | ONCOLOGY | inducers | CANCER-CELL LINES | cytokines | matrix metalloproteinases | EXPRESSION | Enzyme Activators - pharmacology | Gene Expression Regulation, Enzymologic - drug effects | Fibroblasts - enzymology | Interleukin-1beta - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Humans | Carcinogens - pharmacology | Cattle | Fanconi Anemia - enzymology | Fanconi Anemia - pathology | Matrix Metalloproteinase 9 - secretion | Antineoplastic Agents - pharmacology | Catechin - pharmacology | Tretinoin - pharmacology | Cells, Cultured | Antioxidants - pharmacology | Fibroblasts - pathology | Matrix Metalloproteinase Inhibitors - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Fibroblasts - drug effects | Lipopolysaccharides - pharmacology | Doxycycline - pharmacology | Matrix Metalloproteinase 2 - secretion | Anti-Bacterial Agents - pharmacology | Catechin - analogs & derivatives | Fanconi Anemia - drug therapy | Cytokines - pharmacology | Care and treatment | Proteases | Development and progression | Genetic aspects | Health aspects | Fanconi's anemia | Tea | Acids | Anemia | Penicillin | Fibroblasts | Tumor necrosis factor-TNF | Metastasis | Cancer | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 2003, Volume 111, Issue 11, pp. 1665 - 1672
Journal Article
JOURNAL OF CLINICAL INVESTIGATION, ISSN 0021-9738, 06/2003, Volume 111, Issue 11, pp. 1665 - 1672
Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human cathelicidin... 
MEDICINE, RESEARCH & EXPERIMENTAL | LL-37 | PROTEIN | HCAP-18 | FLUID | HUMAN LUNG | CATHELICIDIN | ENDOTHELIAL-CELLS | HOST-DEFENSE | AIRWAY SURFACE | ANTIMICROBIAL ACTIVITY
Journal Article
Phytotherapy Research, ISSN 0951-418X, 11/2013, Volume 27, Issue 11, pp. 1700 - 1707
Journal Article
Neuropharmacology, ISSN 0028-3908, 10/2018, Volume 141, pp. 201 - 213
Given our recent evidence for the role of high mobility group box 1 (HMGB1) in chemotherapy-induced peripheral neuropathy (CIPN) in rats, we examined the... 
Chemotherapy-induced peripheral neuropathy | Paclitaxel | Reactive oxygen species (ROS) | High mobility group box 1 (HMGB1) | Macrophage | CELLS | OXIDATIVE STRESS | SOLUBLE THROMBOMODULIN | RAT | ROOT GANGLION NEURONS | ALLODYNIA | NEUROSCIENCES | CHEMOTHERAPY | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | EXPRESSION | HYPERSENSITIVITY | Hyperalgesia - chemically induced | Peripheral Nervous System Diseases - chemically induced | Pyruvates - pharmacology | Reactive Oxygen Species - metabolism | Clodronic Acid - pharmacology | Minocycline - pharmacology | Coculture Techniques | Male | Phosphoproteins - metabolism | Paclitaxel - antagonists & inhibitors | Thrombomodulin - metabolism | Thiocarbamates - pharmacology | HMGB1 Protein - metabolism | Proline - pharmacology | Membrane Proteins - metabolism | Neurons - metabolism | Sciatic Nerve - drug effects | Phosphorylation - drug effects | Peripheral Nervous System Diseases - complications | Peripheral Nervous System Diseases - immunology | Recombinant Proteins - metabolism | Proline - analogs & derivatives | Hyperalgesia - complications | Receptor for Advanced Glycation End Products - metabolism | Cells, Cultured | Hyperalgesia - prevention & control | Paclitaxel - adverse effects | Imidazoles - pharmacology | Antibodies - pharmacology | Up-Regulation - drug effects | p300-CBP Transcription Factors - metabolism | Macrophages - metabolism | Animals | Acetylcysteine - pharmacology | Macrophages - drug effects | Mice | Pyridines - pharmacology | Receptors, CXCR4 | Ganglia, Spinal - metabolism | Chemotherapy | Cysteine | Chromosomal proteins | Macrophages | Cancer | Cystine | Index Medicus
Journal Article
FEBS Letters, ISSN 0014-5793, 2011, Volume 585, Issue 8, pp. 1113 - 1120
Aggregation of alpha-synuclein (αS) into oligomers is critically involved in the pathogenesis of Parkinson’s disease (PD). Using confocal single-molecule... 
Aggregation | Aromatic interaction | Polyphenol | Parkinson’s disease | Alpha-synuclein | Confocal fluorescence spectroscopy | morin | black tea extract | SIFT | Parkinson's disease | DMSO | dimethylsulfoxide | Purp | cysteine | apigenin | acetyl | myricetin | Desf | fluorescence correlation spectroscopy | tannic acid | Gink | FIDA | Baic | EGCG | Myr | purpurogallin trimethyl ether | Scut | baicalein | rosmarinic acid | alpha-synuclein | Gen | BTE | NDGA | FCS | (−)-epigallocatechin gallate | N-acetylC | scutellarein | scanning for intensely fluorescent targets | VitC | nordihydroguaiaretic acid | Resv | genistein | Quer | fluorescence-intensity distribution analysis | quercetin | resveratrol | vitamin C | Mor | desferrioxamine | ginkgolide B | Api | ANTIOXIDANT ACTIVITY | FIBRILLATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | FLAVONOID BAICALEIN | BETA | CELL BIOLOGY | GREEN TEA | EPIGALLOCATECHIN-3-GALLATE EGCG | IN-VITRO | FIBRILS | BIOPHYSICS | PARKINSONS-DISEASE | Spectrometry, Fluorescence - methods | Humans | Structure-Activity Relationship | Apigenin - chemistry | Dose-Response Relationship, Drug | Flavanones - chemistry | Polyphenols | Flavonoids - pharmacology | Molecular Structure | Parkinson Disease - metabolism | alpha-Synuclein - genetics | Phenols - pharmacology | Recombinant Proteins - metabolism | Deferoxamine - pharmacology | Parkinson Disease - pathology | Flavanones - pharmacology | Recombinant Proteins - chemistry | Antioxidants - pharmacology | Protein Structure, Quaternary - drug effects | alpha-Synuclein - chemistry | Microscopy, Confocal | Iron Chelating Agents - pharmacology | Acetylcysteine - pharmacology | Ascorbic Acid - pharmacology | Phenols - chemistry | Mutation | Flavonoids - chemistry | alpha-Synuclein - metabolism | Apigenin - pharmacology | Microscopy, Fluorescence | Protein Multimerization - drug effects | Index Medicus
Journal Article
Basic & Clinical Pharmacology & Toxicology, ISSN 1742-7835, 04/2014, Volume 114, Issue 4, pp. 293 - 304
Naringin, an active flavonoid isolated from citrus fruit extracts, exhibits biological and pharmacological properties, such as antioxidant activity and... 
OXIDATIVE STRESS | WISTAR RATS | HYPERGLYCEMIA | INDUCED DIABETIC-RATS | ENZYMES | BONE-MARROW | PHARMACOLOGY & PHARMACY | TOXICOLOGY | VENTRICULAR MYOCYTES | P388 CELLS | INDUCED MYOCARDIAL-INFARCTION | PROTECTS | Phosphorylation | Reactive Oxygen Species - metabolism | Nitriles - pharmacology | Apoptosis - drug effects | Plant Extracts - pharmacology | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - metabolism | Membrane Potential, Mitochondrial - drug effects | Hyperglycemia - drug therapy | MAP Kinase Signaling System | p38 Mitogen-Activated Protein Kinases - metabolism | Cell Line | Cell Survival - drug effects | Glucose - adverse effects | Butadienes - pharmacology | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Fruit - chemistry | Flavanones - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Imidazoles - pharmacology | Mitochondria - drug effects | Anthracenes - pharmacology | Animals | Myocytes, Cardiac - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | Myocytes, Cardiac - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Glucose metabolism | Cysteine | Glucose | Dextrose | Heart cells | Index Medicus
Journal Article