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American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2009, Volume 296, Issue 2, pp. 470 - 479
Bacterial endotoxin lipopolysaccharide (LPS) is responsible for the multiorgan dysfunction that characterizes septic shock and is causal in the myocardial... 
Green fluorescent protein- Microtubule-associated protein light chain 3 | Lipopolysaccharide | Oxidative stress | Hl-1 cardiac myocyte | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Mitochondria, Heart - metabolism | Glutathione - metabolism | Mitochondria, Heart - pathology | Nitric Oxide Synthase - antagonists & inhibitors | omega-N-Methylarginine - pharmacology | Mitochondria, Heart - drug effects | Nitroprusside - pharmacology | Autophagy - drug effects | p38 Mitogen-Activated Protein Kinases - metabolism | Nitric Oxide Donors - pharmacology | Cytoprotection | Animals, Newborn | Cells, Cultured | Enzyme Inhibitors - pharmacology | Rats | Mice, Transgenic | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Sirolimus - pharmacology | Hydrogen Peroxide - metabolism | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Acetylcysteine - pharmacology | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Mice | Nitric Oxide Synthase - metabolism | Pyridines - pharmacology | Oxidative Stress - drug effects | Nitric Oxide - metabolism | Signal transduction | Bacteria | Oxidation | Biochemistry | Cytokines | Sugar | Index Medicus | green fluorescent protein-microtubule-associated protein light chain 3 | lipopolysaccharide | HL-1 cardiac myocyte | oxidative stress
Journal Article
Biochemical journal, ISSN 1470-8728, 08/2013, Volume 454, Issue 2, pp. 201 - 208
NAC (N-acetyl-L-cysteine) is commonly used to identify and test ROS (reactive oxygen species) inducers, and to inhibit ROS. In the present study, we identified... 
Catalase | N-acetyl-L-cysteine (NAC) | Proteasome inhibitor | Reactive oxygen species (ROS) | Forkhead box protein M1 (FOXM1) | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Free Radical Scavengers - pharmacology | Oxidants - pharmacology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Acetylcysteine - metabolism | Proteasome Inhibitors - chemistry | Proteasome Inhibitors - metabolism | Viral Proteins - metabolism | Antineoplastic Agents, Phytogenic - antagonists & inhibitors | Chromans - metabolism | Proteasome Endopeptidase Complex - drug effects | Chromans - pharmacology | Dioxolanes - pharmacology | Forkhead Transcription Factors - metabolism | Forkhead Transcription Factors - antagonists & inhibitors | Ubiquitinated Proteins - metabolism | Recombinant Proteins - metabolism | Recombinant Proteins - antagonists & inhibitors | Free Radical Scavengers - metabolism | Proteasome Inhibitors - pharmacology | Catalase - genetics | Chromans - antagonists & inhibitors | Hydrogen Peroxide - pharmacology | Viral Proteins - genetics | Oxidants - antagonists & inhibitors | Dioxolanes - antagonists & inhibitors | Forkhead Transcription Factors - genetics | Catalase - metabolism | Reactive Oxygen Species - antagonists & inhibitors | Protein Stability - drug effects | Acetylcysteine - pharmacology | Cell Line, Tumor | Cytomegalovirus - enzymology | Proteasome Endopeptidase Complex - metabolism | Antineoplastic Agents, Phytogenic - pharmacology | Forkhead Box Protein M1 | Hydrogen Peroxide - antagonists & inhibitors | Index Medicus | N-acetyl-l-cysteine (NAC) | proteasome inhibitor | reactive oxygen species (ROS) | catalase
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 06/2003, Volume 111, Issue 11, pp. 1665 - 1672
  Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human... 
Index Medicus | Abridged Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 08/2007, Volume 2, Issue 8, pp. e693 - e693
Background. A major obstacle for successful cancer treatment often is the development of drug resistance in cancer cells during chemotherapy. Therefore, there... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Free Radical Scavengers - pharmacology | Leukemia - pathology | Reactive Oxygen Species - metabolism | Antibiotics, Antineoplastic - pharmacology | Oxidation-Reduction | Apoptosis - drug effects | Humans | Leukemia - drug therapy | Cell Line, Tumor - drug effects | Leukemia - metabolism | Antimalarials - pharmacology | Artemisinins - pharmacology | Animals | Acetylcysteine - pharmacology | Mice | Drug Resistance, Neoplasm - physiology | Doxorubicin - pharmacology | Drug Screening Assays, Antitumor | Drug resistance in microorganisms | Cysteine | Anthracyclines | Chemotherapy | Malaria | Sarcoma | Leukemia | Analysis | T cells | Apoptosis | Cancer | Drugs | Toxicity | Lipid peroxidation | Acetylcysteine | Cytotoxicity | Lymphocytes T | Metastasis | Drug resistance | Synergism | Cancer therapies | Doxorubicin | Proteins | Antioxidants | Mitochondria | Chinese medicine | Antitumor agents | Immunology | Lymphocytes | Artesunate | Tumor necrosis factor-TNF | Biocompatibility | Drug dosages | Deoxyribonucleic acid--DNA | Vector-borne diseases | Killing | Medical research | Oxygen | Tumor cells | Tumor cell lines | Side effects | Molecular modelling | Cell death | Natural products | Kaposi's sarcoma | Synergistic effect | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Clinical cancer research, ISSN 1557-3265, 06/2004, Volume 10, Issue 11, pp. 3839 - 3852
Purpose: The purpose of this study was to examine interactions between the proteasome inhibitor bortezomib (Velcade) and the histone deacetylase (HDAC)... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Free Radical Scavengers - pharmacology | Reactive Oxygen Species | Oxidative Stress | Humans | Membrane Glycoproteins - biosynthesis | Oxygen - metabolism | Dose-Response Relationship, Drug | Protease Inhibitors - pharmacology | Proto-Oncogene Proteins c-bcl-2 - metabolism | Multiple Myeloma - drug therapy | Intracellular Membranes - pathology | Antineoplastic Agents - pharmacology | X-Linked Inhibitor of Apoptosis Protein | Hydroxamic Acids - pharmacology | Syndecans | Tumor Suppressor Proteins - metabolism | Bortezomib | Cell Survival | Cyclin-Dependent Kinase Inhibitor p21 | Neoplasm Proteins - biosynthesis | Cell Cycle Proteins - metabolism | Enzyme Inhibitors - pharmacology | Proteoglycans - biosynthesis | Cyclin D1 - biosynthesis | Mitochondria - metabolism | Multiple Myeloma - metabolism | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Blotting, Western | Sodium Oxybate - pharmacology | Cyclin-Dependent Kinase Inhibitor p27 | Multiple Myeloma - pathology | Proteins - metabolism | Cell Cycle | Membrane Potentials | Myeloid Cell Leukemia Sequence 1 Protein | Acetylcysteine - pharmacology | Cell Line, Tumor | Cytosol - metabolism | Syndecan-1 | Histone Deacetylase Inhibitors | Pyrazines - pharmacology | Apoptosis | Boronic Acids - pharmacology | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 01/2011, Volume 108, Issue 4, pp. 1462 - 1467
Journal Article