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Cell (Cambridge), ISSN 0092-8674, 2018, Volume 172, Issue 5, pp. 897 - 909.e21
X-linked Dystonia-Parkinsonism (XDP) is a Mendelian neurodegenerative disease that is endemic to the Philippines and is associated with a founder haplotype. We... 
DYT3 | XDP | dystonia | transcriptome assembly | retrotransposon | Parkinson’s disease | genome assembly | intron retention | SVA | TAF1 | Parkinson's disease | II ELONGATION RATE | STEM-CELLS | HUMAN-DISEASE | RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTRON RETENTION | GENE-EXPRESSION | INTERFERENCE | SEQUENCING DATA | VARIATION DISCOVERY | CELL BIOLOGY | TATA-Binding Protein Associated Factors - metabolism | Humans | Histone Acetyltransferases - genetics | Nerve Degeneration - genetics | Male | Genetic Loci | Transcription Factor TFIID - metabolism | RNA, Messenger - metabolism | Transcription Factor TFIID - genetics | Haplotypes - genetics | Short Interspersed Nucleotide Elements | Base Sequence | Histone Acetyltransferases - metabolism | Minisatellite Repeats - genetics | Female | Genetic Diseases, X-Linked - genetics | Neurons - metabolism | Alu Elements - genetics | Induced Pluripotent Stem Cells - metabolism | Dystonic Disorders - genetics | Introns - genetics | Alternative Splicing - genetics | RNA, Messenger - genetics | Transcriptome - genetics | TATA-Binding Protein Associated Factors - genetics | CRISPR-Cas Systems - genetics | Nerve Degeneration - pathology | Family | High-Throughput Nucleotide Sequencing | Models, Genetic | Genome, Human | Neural Stem Cells - metabolism | Cohort Studies | Nervous system diseases | Analysis | Genomics | Genetic research | Genetic aspects | Dystonia
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 476, Issue 7360, pp. 298 - 303
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 471, Issue 7337, pp. 189 - 195
B-cell non-Hodgkin's lymphoma comprises biologically and clinically distinct diseases the pathogenesis of which is associated with genetic lesions affecting oncogenes and tumour-suppressor genes... 
CBP | COACTIVATOR | HEMATOPOIESIS | ACETYLATION | P300 | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | CREB-BINDING-PROTEIN | CYCLE ARREST | ACUTE MYELOID-LEUKEMIA | P53 | Histone Acetyltransferases - deficiency | Recurrence | Acetyltransferases - metabolism | Histone Acetyltransferases - chemistry | Humans | E1A-Associated p300 Protein - genetics | Gene Expression Regulation, Neoplastic | Histone Acetyltransferases - genetics | CREB-Binding Protein - chemistry | E1A-Associated p300 Protein - metabolism | Lymphoma, B-Cell - genetics | Acetyltransferases - genetics | Mutation, Missense - genetics | CREB-Binding Protein - genetics | DNA-Binding Proteins - metabolism | CREB-Binding Protein - metabolism | Lymphoma, Follicular - genetics | Acetyltransferases - deficiency | Base Sequence | Histone Acetyltransferases - metabolism | Lymphoma, B-Cell - enzymology | HEK293 Cells | Acetylation | CREB-Binding Protein - deficiency | Lymphoma, Large B-Cell, Diffuse - pathology | Lymphoma, Follicular - pathology | Cells, Cultured | E1A-Associated p300 Protein - chemistry | Lymphoma, Large B-Cell, Diffuse - enzymology | Tumor Suppressor Protein p53 - metabolism | Protein Structure, Tertiary - genetics | Mutation - genetics | Acetyl Coenzyme A - metabolism | Acetyltransferases - chemistry | Animals | Lymphoma, B-Cell - pathology | Polymorphism, Single Nucleotide - genetics | Protein Binding | Lymphoma, Follicular - enzymology | Mice | E1A-Associated p300 Protein - deficiency | Lymphoma, Large B-Cell, Diffuse - genetics | Proto-Oncogene Proteins c-bcl-6 | Sequence Deletion - genetics | Lymphomas | Genetic aspects | B cells | Gene mutations | Health aspects | Abnormalities | Proteins | Congenital diseases | Pathogenesis | Genes | Cell cycle | Genomes | Genetic engineering | Mutation | Binding sites
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2004, Volume 116, Issue 1, pp. 75 - 86
Gene expression is a coordinated multistep process that begins with transcription and RNA processing in the nucleus followed by mRNA export to the cytoplasm... 
HNRNP-LIKE PROTEINS | YEAST | COACTIVATOR | POLY(A)(+) RNA | INTERACTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | COUPLING TRANSCRIPTION | YRA1P | SACCHAROMYCES-CEREVISIAE | NUCLEOCYTOPLASMIC TRANSPORT | CELL BIOLOGY | Nucleocytoplasmic Transport Proteins | RNA-Binding Proteins - genetics | Yeasts | Acetyltransferases - metabolism | Transcriptional Activation - genetics | Histone Acetyltransferases | Nuclear Proteins - isolation & purification | Active Transport, Cell Nucleus - physiology | DNA, Complementary - genetics | Molecular Sequence Data | Amino Acid Sequence - genetics | RNA, Messenger - metabolism | RNA-Binding Proteins - isolation & purification | Acetyltransferases - genetics | Promoter Regions, Genetic - genetics | Porins | Genes, Regulator - genetics | Cell Nucleus - metabolism | Nuclear Proteins - deficiency | Ribonucleoproteins - genetics | Saccharomyces cerevisiae Proteins - isolation & purification | Gene Expression Regulation, Fungal - genetics | Fungal Proteins - isolation & purification | Nuclear Proteins - genetics | DNA, Complementary - analysis | Base Sequence - genetics | RNA, Messenger - genetics | Nuclear Pore - genetics | Nuclear Proteins - metabolism | Ribonucleoproteins - metabolism | Fungal Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Nuclear Pore - metabolism | Genes, Lethal - genetics | Saccharomyces cerevisiae Proteins - metabolism | RNA-Binding Proteins - metabolism | Fungal Proteins - metabolism | Histones | Genetic research | Messenger RNA | Genetic transcription | Research
Journal Article
Journal Article
Cell (Cambridge), ISSN 0092-8674, 2005, Volume 123, Issue 4, pp. 593 - 605
.... Biochemical, genetic, and gene-expression analyses show that Rpd3 exists in two distinct complexes... 
RNA-POLYMERASE-II | CHROMATIN REMODELING COMPLEX | TRANSCRIPTION ELONGATION-FACTORS | REGULATES H3 METHYLATION | TARGETED RECRUITMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | IN-VIVO | GENE-EXPRESSION | DEACETYLASE COMPLEX | SACCHAROMYCES-CEREVISIAE | H2A VARIANT HTZ1 | CELL BIOLOGY | Acetyltransferases - metabolism | Oligonucleotide Array Sequence Analysis | Saccharomyces cerevisiae - genetics | Methyltransferases - metabolism | Methyltransferases - genetics | Molecular Sequence Data | RNA Polymerase II - metabolism | Acetyltransferases - genetics | Silent Information Regulator Proteins, Saccharomyces cerevisiae - genetics | Saccharomyces cerevisiae - metabolism | Sirtuin 2 | Gene Deletion | Lysine - metabolism | Acetylation | Cyclin-Dependent Kinases - genetics | Sirtuins - genetics | Repressor Proteins - metabolism | Gene Expression Regulation, Fungal | Amino Acid Sequence | Histone Deacetylases - genetics | Silent Information Regulator Proteins, Saccharomyces cerevisiae - metabolism | Repressor Proteins - genetics | Histone Deacetylases - metabolism | Saccharomyces cerevisiae Proteins - genetics | Transcription Factors - genetics | Mutation - genetics | Down-Regulation - genetics | Sequence Homology, Amino Acid | Transcription Factors - metabolism | Epistasis, Genetic | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Histones - metabolism | Methylation | Sirtuins - metabolism | Cluster Analysis | Suppression, Genetic | Medical colleges | Methyltransferases | RNA | Lysine | Medical genetics | Histones | Nucleosomes
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 11/2011, Volume 89, Issue 5, pp. 675 - 681
Journal Article
BMC Genomics, ISSN 1471-2164, 04/2006, Volume 7, Issue 1, pp. 90 - 90
Background: Post-translational modification of histones resulting in chromatin remodelling plays a key role in the regulation of gene expression. Here we... 
BREAST-CANCER | CBP | METHYLATION | INHIBITION | BOOTSTRAP | ACETYLATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENETICS & HEREDITY | PATTERNS | MUTATIONS | REPRODUCIBILITY | PROGRESSION | Neoplasms - metabolism | Protein Methyltransferases | Pancreatic Neoplasms - metabolism | Colorectal Neoplasms - genetics | Histone Acetyltransferases - biosynthesis | Humans | Lung Neoplasms - metabolism | Protein Processing, Post-Translational - genetics | DNA, Complementary - genetics | Gene Expression Regulation, Neoplastic | Histone Acetyltransferases - genetics | Male | Histone-Lysine N-Methyltransferase - biosynthesis | Breast Neoplasms - metabolism | Ovarian Neoplasms - genetics | Polymorphism, Single-Stranded Conformational | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | Polymerase Chain Reaction | Female | Ovarian Neoplasms - metabolism | Neoplasm Proteins - genetics | Colorectal Neoplasms - metabolism | Lung Neoplasms - genetics | Histone-Lysine N-Methyltransferase - genetics | Histone Deacetylases - genetics | Neoplasm Proteins - biosynthesis | Linear Models | Pancreatic Neoplasms - genetics | Gene Expression Regulation, Enzymologic | Breast Neoplasms - genetics | Carcinoma - genetics | Carcinoma - metabolism | DNA, Neoplasm - genetics | Histones - metabolism | Histone Code - genetics | Cluster Analysis
Journal Article
European journal of human genetics : EJHG, ISSN 1018-4813, 09/2015, Volume 23, Issue 9, pp. 1165 - 1170
...  European Journal of Human Genetics (2015) 23, 11651170& 2015 Macmillan Publishers Limited All rights reserved 1018-4813/15 http://www.nature.com/ejhg Web End... 
BLEPHAROPHIMOSIS | OHDO SYNDROME | DE-NOVO MUTATIONS | MENTAL-RETARDATION | HISTONE ACETYLTRANSFERASE KAT6B | CAUSE GENITOPATELLAR SYNDROME | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | Scrotum - abnormalities | Kidney - pathology | Exons | Humans | Joint Instability - genetics | Child, Preschool | Histone Acetyltransferases - genetics | Joint Instability - pathology | Blepharophimosis - pathology | Male | Intellectual Disability - genetics | Exome | Blepharophimosis - genetics | Heart Defects, Congenital - genetics | Psychomotor Disorders - genetics | Congenital Hypothyroidism - diagnosis | DNA Mutational Analysis | Blepharophimosis - diagnosis | Congenital Hypothyroidism - genetics | Facies | Patella - abnormalities | Craniofacial Abnormalities - pathology | Female | Scrotum - pathology | Craniofacial Abnormalities - genetics | Severity of Illness Index | Diagnosis, Differential | Gene Expression | Joint Instability - diagnosis | Genetic Association Studies | Urogenital Abnormalities - diagnosis | Heart Defects, Congenital - pathology | Intellectual Disability - pathology | Psychomotor Disorders - pathology | Genotype | Patella - pathology | Phenotype | Urogenital Abnormalities - pathology | Craniofacial Abnormalities - diagnosis | Kidney - abnormalities | Intellectual Disability - diagnosis | Psychomotor Disorders - diagnosis | Congenital Hypothyroidism - pathology | Heart Defects, Congenital - diagnosis | Mutation | Urogenital Abnormalities - genetics | Pediatrics | Phenotypes | Congenital diseases | Statistical analysis | Splicing | Intellectual disabilities | Thyroid gland | Blepharophimosis | Gene deletion | Defects | Haploinsufficiency | Medicine | Genotype & phenotype | Hospitals | Molecular modelling | Clonal deletion | Genetics | Genotypes | Thyroid | Life Sciences | Human genetics
Journal Article
Genome research, ISSN 1088-9051, 2012, Volume 22, Issue 4, pp. 735 - 745
Journal Article