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Journal of Biological Chemistry, ISSN 0021-9258, 01/2016, Volume 291, Issue 5, pp. 2422 - 2434
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2011, Volume 17, Issue 1, pp. 55 - 63
Journal Article
Journal Article
BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 12/2013, Volume 1831, Issue 12, pp. 1657 - 1664
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2013, Volume 123, Issue 10, pp. 4344 - 4358
Escape of prostate cancer (PCa) cells from ionizing radiation-induced (IR-induced) killing leads to disease progression and cancer relapse. The influence of... 
MEDICINE, RESEARCH & EXPERIMENTAL | SPHINGOLIPID BIOSYNTHESIS | INDUCED APOPTOSIS | RAT EMBRYO CELLS | DOWN-REGULATION | GENE-EXPRESSION | RANDOMIZED CONTROLLED-TRIAL | C-JUN | IONIZING-RADIATION | HUMAN GLIOMA-CELLS | ADENOCARCINOMA CELL-LINE | Prostatic Neoplasms - radiotherapy | Acid Ceramidase - antagonists & inhibitors | Humans | Radiation Tolerance | Male | Neoplasm Recurrence, Local - enzymology | Transcription Factor AP-1 - metabolism | Radiation-Sensitizing Agents - administration & dosage | Acid Ceramidase - metabolism | Amides - pharmacology | Promoter Regions, Genetic | Prostatic Neoplasms - pathology | Gene Expression | Acid Ceramidase - genetics | Neoplasm Recurrence, Local - prevention & control | Radiation-Sensitizing Agents - pharmacology | Transcriptional Activation - radiation effects | Injections, Intraperitoneal | Sphingolipids - metabolism | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Proto-Oncogene Proteins c-jun - metabolism | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Protein Binding | Gene Expression Regulation, Neoplastic - radiation effects | Mice | Propanolamines - administration & dosage | Propanolamines - pharmacology | Amides - administration & dosage | Enzyme Induction - radiation effects | Enzymes | Care and treatment | Ionizing radiation | Hydrolases | Genetic aspects | Research | Properties | Radiotherapy | Prostate cancer | Proteins | Studies | Cell culture | Radiation therapy | Kinases | Gene expression | Cancer therapies | Tumors | Index Medicus | Abridged Index Medicus
Journal Article
Oncology Reports, ISSN 1021-335X, 10/2017, Volume 38, Issue 4, pp. 1932 - 1940
Journal Article
European Journal of Cancer, ISSN 0959-8049, 2015, Volume 52, pp. 163 - 172
Abstract Background Acid ceramidase (AC), a key enzyme in ceramide metabolism, plays a role in cancer progression and resistance to therapy. However, the role... 
Hematology, Oncology and Palliative Medicine | Ceramide | Head and neck cancer | Acid ceramidase | Cell death | Cisplatin | APOPTOSIS | CHEMOTHERAPY | INVASION | INHIBITION | ONCOLOGY | PROSTATE-CANCER | RESISTANCE | MELANOMA-CELLS | UP-REGULATION | EXPRESSION | FASL GENE-THERAPY | Acid Ceramidase - antagonists & inhibitors | Apoptosis - drug effects | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Gene Expression Regulation, Neoplastic | Male | RNA, Messenger - metabolism | Dose-Response Relationship, Drug | Squamous Cell Carcinoma of Head and Neck | Transfection | RNA Interference | Time Factors | Antineoplastic Agents - pharmacology | Head and Neck Neoplasms - enzymology | Acid Ceramidase - metabolism | Cell Survival - drug effects | Carcinoma, Squamous Cell - enzymology | Acid Ceramidase - genetics | Ceramides - metabolism | Enzyme Inhibitors - pharmacology | Head and Neck Neoplasms - drug therapy | Cisplatin - pharmacology | Head and Neck Neoplasms - pathology | Xenograft Model Antitumor Assays | Animals | Carcinoma, Squamous Cell - drug therapy | Mice, Nude | Cell Line, Tumor | Head and Neck Neoplasms - genetics | Mice, Inbred BALB C | RNAi Therapeutics | Cell Cycle - drug effects | Antimitotic agents | Enzymes | Chemotherapy | Physiological aspects | Development and progression | Antineoplastic agents | Cancer | Index Medicus
Journal Article