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Journal Article
Journal of Neuroscience, ISSN 0270-6474, 10/2012, Volume 32, Issue 43, pp. 15148 - 15157
Several behavioral effects of nicotine are mediated by changes in serotonin (5-HT) release in brain areas that receive serotonergic afferents from the dorsal... 
Electric Stimulation | Rats, Wistar | Dihydro-beta-Erythroidine - pharmacology | Male | Nicotinic Antagonists - pharmacology | Raphe Nuclei - cytology | Excitatory Postsynaptic Potentials - drug effects | Nicotine - pharmacology | Excitatory Postsynaptic Potentials - physiology | Muscarinic Antagonists - pharmacology | Egtazic Acid - analogs & derivatives | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Tetrodotoxin - pharmacology | Cadmium Chloride - pharmacology | Cholinergic Agonists - pharmacology | Ryanodine - pharmacology | Animals, Newborn | Serotonergic Neurons - physiology | Presynaptic Terminals - drug effects | Acetylcholine - pharmacology | Enzyme Inhibitors - pharmacology | Glutamic Acid - physiology | Rats | Atropine - pharmacology | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Chelating Agents - pharmacology | Aconitine - pharmacology | GABA Antagonists - pharmacology | Physostigmine - pharmacology | Patch-Clamp Techniques | Animals | Egtazic Acid - pharmacology | Receptors, Nicotinic - physiology | Nicotine - analogs & derivatives | Serotonin - metabolism | In Vitro Techniques | Serotonergic Neurons - cytology | Index Medicus
Journal Article
Psychopharmacology, ISSN 0033-3158, 5/2014, Volume 231, Issue 9, pp. 1975 - 1985
Neuronal nicotinic acetylcholine receptors (nAChRs) play a modulatory role in cognition, and zebrafish provide a preclinical model to study learning and... 
Neurosciences | α-Conotoxin | Scopolamine | Neuronal nicotinic receptors | Zebrafish | Cholinergic system | Methyllycaconitine | Mecamylamine | Biomedicine | Dihydro-β-erythroidine | Pharmacology/Toxicology | T-maze | Psychiatry | Spatial memory | Dihydro-beta-erythroidine | DANIO-RERIO | TASK | CHOLINERGIC CHANNEL ACTIVATOR | PSYCHIATRY | BEHAVIOR | INVOLVEMENT | Spatialmemory | SYNAPTIC PLASTICITY | NEUROSCIENCES | COGNITIVE FUNCTION | SELECTIVE STIMULATION | PARTIAL AGONIST | PHARMACOLOGY & PHARMACY | alpha-Conotoxin | WORKING-MEMORY | Memory - drug effects | Cholinergic Agents - pharmacology | Dihydro-beta-Erythroidine - pharmacology | Nicotinic Antagonists - pharmacology | Nicotine - pharmacology | Dose-Response Relationship, Drug | Scopolamine Hydrobromide - pharmacology | Muscarinic Antagonists - pharmacology | Mecamylamine - pharmacology | Neurons - physiology | Swimming | Neurons - drug effects | Nicotinic Agonists - pharmacology | Azocines - chemistry | Receptors, Nicotinic - metabolism | Alkaloids - pharmacology | Maze Learning - physiology | Zebrafish Proteins - metabolism | Quinolizines - pharmacology | Aconitine - analogs & derivatives | Aconitine - pharmacology | Maze Learning - drug effects | Conotoxins - pharmacology | Animals | Nicotinic Antagonists - chemistry | Zebrafish - physiology | Azocines - pharmacology | Alkaloids - chemistry | Quinolizines - chemistry | Memory - physiology | Learning | Receptors | Memory | Zebra fish | Physiological aspects | Genetic aspects | Acetylcholine | Research | Fish | Psychopharmacology | Animal memory | Index Medicus
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2005, Volume 315, Issue 3, pp. 1346 - 1353
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/1997, Volume 17, Issue 2, pp. 576 - 585
Presynaptic nicotinic acetylcholine receptors (nAChRs) are present in many regions of the brain and potentially serve as targets for the pharmacological action... 
GABA | calcium | facilitation | thalamus (sensory nuclei) | nicotinic acetylcholine receptors | presynaptic | ADRENAL CHROMAFFIN CELLS | INTERPEDUNCULAR NUCLEUS | FROG NEUROMUSCULAR-JUNCTION | OPTIC-NERVE TERMINALS | RAT CENTRAL NEURONS | NEUROSCIENCES | LATERAL GENICULATE-NUCLEUS | ACETYLCHOLINE-RECEPTORS | SUBUNIT MESSENGER-RNAS | CHOLINERGIC RECEPTORS | EXCITATORY SYNAPTIC TRANSMISSION | Thalamic Nuclei - metabolism | Dihydro-beta-Erythroidine - pharmacology | Lobeline - pharmacology | Nicotinic Antagonists - pharmacology | Pyridazines - pharmacology | Cations, Divalent - pharmacology | Nicotine - pharmacology | Quinolizines | Calcium Channels - physiology | Calcium - physiology | Receptors, Nicotinic - chemistry | Receptors, GABA-A - drug effects | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Receptors, Nicotinic - deficiency | Dimethylphenylpiperazinium Iodide - pharmacology | Ion Transport | gamma-Aminobutyric Acid - secretion | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Microcystins | Alkaloids - pharmacology | Mice, Inbred C57BL | Atropine - pharmacology | Aconitine - analogs & derivatives | Marine Toxins - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Neurons, Afferent - physiology | GABA Antagonists - pharmacology | Mice, Knockout | Carbachol - pharmacology | Arousal - physiology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Patch-Clamp Techniques | Animals | Azocines | Receptors, Nicotinic - physiology | Bacterial Toxins - pharmacology | Thalamic Nuclei - secretion | Mice | Pyridines - pharmacology | Receptors, Nicotinic - genetics | Index Medicus
Journal Article
Journal of Neurophysiology, ISSN 0022-3077, 12/2005, Volume 94, Issue 6, pp. 4131 - 4144
The effects of pregnenolone sulfate (PREGS), a putative neurosteroid, on the transmission of perforant path–granule cell synapses were investigated with an... 
TRANSMITTER RELEASE | PHYSIOLOGY | GLUTAMATE RELEASE | CALCIUM-CHANNELS | LINKED-IMMUNOSORBENT-ASSAY | NICOTINIC ACETYLCHOLINE-RECEPTOR | INCREASES HIPPOCAMPAL ACETYLCHOLINE | RAT-BRAIN | ALPHA-BUNGAROTOXIN | AGED RATS | NEUROSCIENCES | METHYL-D-ASPARTATE | Excitatory Postsynaptic Potentials - radiation effects | Synaptic Transmission - physiology | Rats, Wistar | Calcium - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Kainic Acid - analogs & derivatives | Male | Nicotinic Antagonists - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Diagnostic Imaging - methods | Dose-Response Relationship, Drug | Drug Interactions | Time Factors | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Pregnenolone - pharmacology | Tetrodotoxin - pharmacology | Neurons - drug effects | Electric Stimulation - methods | Haloperidol - pharmacology | Nicotinic Agonists - pharmacology | Calcium - pharmacology | Presynaptic Terminals - drug effects | Kainic Acid - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Aconitine - analogs & derivatives | Bicuculline - pharmacology | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Hippocampus - cytology | Ethylenediamines - pharmacology | GABA Antagonists - pharmacology | Animals | Benzylidene Compounds - pharmacology | Analysis of Variance | Dopamine Antagonists - pharmacology | Pyridines - pharmacology | In Vitro Techniques | Bungarotoxins - pharmacology | Index Medicus
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 09/2003, Volume 18, Issue 5, pp. 1155 - 1168
Tonic impulse flow in the septohippocampal GABAergic pathway is essential for normal cognitive functioning and is sustained, in part, by acetylcholine (ACh)... 
Learning and memory | Septum | Metabotropic | Cognition | Theta rhythm | Glutamate | DIAGONAL BAND COMPLEX | PARVALBUMIN | CA1 INTERNEURONS | cognition | ALZHEIMERS-DISEASE | IMPULSE FLOW | metabotropic | NEUROSCIENCES | septum | theta rhythm | ACETYLCHOLINE-RECEPTORS | learning and memory | MEDIAL SEPTAL AREA | CENTRAL-NERVOUS-SYSTEM | BASAL FOREBRAIN | RAT HIPPOCAMPUS | glutamate | Muscarinic Agonists - pharmacology | gamma-Aminobutyric Acid - metabolism | Cell Count | Septum of Brain - physiology | Parvalbumins - metabolism | Male | Nicotinic Antagonists - pharmacology | Drug Interactions | Neuroprotective Agents - pharmacology | Septum of Brain - ultrastructure | Vesicular Glutamate Transport Protein 2 | Muscarinic Antagonists - pharmacology | Hippocampus - ultrastructure | Tetrodotoxin - pharmacology | Chromones - pharmacology | Animals, Newborn | Membrane Potentials - drug effects | Drug Administration Routes | Acyclovir - pharmacology | Rats | Atropine - pharmacology | Synapses - ultrastructure | Excitatory Amino Acid Antagonists - pharmacology | Bicuculline - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Immunohistochemistry - methods | Glycine - pharmacology | Microscopy, Electron - methods | Muscarine - pharmacology | Glycine - analogs & derivatives | Electric Conductivity | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Nicotine - pharmacology | Dose-Response Relationship, Drug | Resorcinols - pharmacology | Cycloleucine - pharmacology | Tubocurarine - pharmacology | Synapses - metabolism | Neurons - physiology | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Neurons - drug effects | Nicotinic Agonists - pharmacology | Vesicular Transport Proteins | Acyclovir - analogs & derivatives | Valine - analogs & derivatives | Aconitine - analogs & derivatives | Aconitine - pharmacology | Hippocampus - cytology | Membrane Potentials - physiology | Animals | Carrier Proteins - metabolism | Membrane Transport Proteins | Choline - pharmacology | Microscopy, Electron - instrumentation | Valine - pharmacology | In Vitro Techniques | Cycloleucine - analogs & derivatives | Bungarotoxins - pharmacology | Index Medicus
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2006, Volume 540, Issue 1, pp. 96 - 106
Male Wistar rats were trained to discriminate (−)-nicotine (0.4 mg/kg) from saline under a two-lever, fixed-ratio 10 schedule of water reinforcement. During... 
Drug discrimination | Rat | Nicotinic acetylcholine receptor | Cannabinoid system | Nicotine | nicotine | DIHYDRO-BETA-ERYTHROIDINE | rat | ANTAGONIST SR141716A | BEHAVIOR | PLACE PREFERENCES | ANANDAMIDE TRANSPORT | drug discrimination | AFFINITY | PHARMACOLOGY & PHARMACY | cannabinoid system | MEDIATED RESPONSES | XENOPUS OOCYTES | BRAIN | nicotinic acetylcholine receptor | AGONIST | Receptor, Cannabinoid, CB2 - physiology | Rats, Wistar | Cannabinoid Receptor Antagonists | Dihydro-beta-Erythroidine - pharmacology | Bornanes - pharmacology | Receptors, Cannabinoid - physiology | Male | Nicotinic Antagonists - pharmacology | Azetidines - pharmacology | Benzoxazines | Receptor, Cannabinoid, CB2 - antagonists & inhibitors | Receptor, Cannabinoid, CB1 - physiology | Nicotine - pharmacology | Dose-Response Relationship, Drug | Discrimination Learning - drug effects | Mecamylamine - pharmacology | Benzamides - pharmacology | Cyclohexanols - pharmacology | Endocannabinoids | Nicotinic Agonists - pharmacology | Carbamates - pharmacology | Pyrazoles - pharmacology | Morpholines - pharmacology | Rats | Aconitine - analogs & derivatives | Aconitine - pharmacology | Arachidonic Acids - pharmacology | Discrimination Learning - physiology | Naphthalenes - pharmacology | Drug Synergism | Animals | Receptors, Nicotinic - physiology | Polyunsaturated Alkamides - pharmacology | Pyridines - pharmacology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Enzymes | Pyridine | Hydrolases | Drug therapy, Combination | Cyclohexanol | Fatty acids | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 02/2011, Volume 31, Issue 7, pp. 2537 - 2548
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 07/2000, Volume 12, Issue 7, pp. 2475 - 2485
Nicotinic acetylcholine receptors (nAChRs) are expressed in the midbrain ascending dopaminergic system, a target of many addictive drugs. Here we assessed the... 
choline | nicotine | mesencephalon | dopaminergic neurons | Dopaminergic neurons | Mesencephalon | Choline | Nicotine | CA2+ CHANNELS | RELEASE | RAT STRIATAL SYNAPTOSOMES | NEUROSCIENCES | MIDBRAIN DOPAMINERGIC-NEURONS | IMMUNOCYTOCHEMICAL LOCALIZATION | MESSENGER-RNA | Ca2 | CENTRAL-NERVOUS-SYSTEM | DIVERSITY | BRAIN | SUBUNIT | Glycine - analogs & derivatives | Calcium - metabolism | Dihydro-beta-Erythroidine - pharmacology | 2-Amino-5-phosphonovalerate - pharmacology | Endoplasmic Reticulum - metabolism | Substantia Nigra - cytology | Nicotine - pharmacology | Mice, Mutant Strains | 6-Cyano-7-nitroquinoxaline-2,3-dione - pharmacology | Indoles - pharmacology | Fura-2 | Tetrodotoxin - pharmacology | Action Potentials - drug effects | Nicotinic Agonists - pharmacology | Insecticides - pharmacology | Nifedipine - pharmacology | Receptors, Nicotinic - metabolism | Neurons - chemistry | Presynaptic Terminals - chemistry | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Tyrosine 3-Monooxygenase - analysis | Aconitine - analogs & derivatives | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Action Potentials - physiology | Patch-Clamp Techniques | Polyamines - pharmacology | Animals | Glycine - pharmacology | Neurons - enzymology | Choline - pharmacology | Benzoates - pharmacology | Mice | In Vitro Techniques | Receptors, Nicotinic - genetics | Substantia Nigra - physiology | Fluorescent Dyes | Nootropic Agents - pharmacology | Bungarotoxins - pharmacology | Index Medicus
Journal Article
Journal of Neurochemistry, ISSN 0022-3042, 2001, Volume 79, Issue 3, pp. 489 - 498
We have investigated mechanisms of nicotine-induced phosphorylation of extracellular signal-regulated protein kinase (p42/44 MAP kinase, ERK) and cAMP response... 
Nicotinic | Mitogen-activated protein kinase | Acetylcholine receptor | PC12 cells | cAMP response element binding protein | Nicotine | nicotine | nicotinic | C-FOS | TYROSINE-HYDROXYLASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-BUNGAROTOXIN | NEUROSCIENCES | NERVE GROWTH-FACTOR | mitogen-activated protein kinase | acetylcholine receptor | TRANSMITTER RELEASE | ACETYLCHOLINE-RECEPTORS | MESSENGER-RNA | SYNAPTIC TRANSMISSION | IMMEDIATE-EARLY GENES | MAP Kinase Signaling System - physiology | Phosphorylation | Calcium - metabolism | ras Proteins - metabolism | Neurons - cytology | Nicotinic Antagonists - pharmacology | PC12 Cells | Nicotine - pharmacology | Hexamethonium - pharmacology | Tubocurarine - pharmacology | Neurons - metabolism | Bungarotoxins - metabolism | Nicotinic Agonists - pharmacology | Insecticides - pharmacology | Nifedipine - pharmacology | Receptors, Nicotinic - metabolism | Enzyme Inhibitors - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Nerve Growth Factor - pharmacology | Rats | Aconitine - analogs & derivatives | Aconitine - pharmacology | Calcium Channel Blockers - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Potassium - pharmacology | Sulfonamides - pharmacology | Animals | MAP Kinase Signaling System - drug effects | Cyclic AMP Response Element-Binding Protein - metabolism | Benzylamines - pharmacology | Calmodulin - antagonists & inhibitors | Bungarotoxins - pharmacology | Mitogen-Activated Protein Kinases - metabolism | extracellular signal-regulated kinase | Index Medicus
Journal Article
The Journal of Physiology, ISSN 0022-3751, 01/2009, Volume 587, Issue 2, pp. 345 - 361
Journal Article
Behavioral Neuroscience, ISSN 0735-7044, 10/2012, Volume 126, Issue 5, pp. 720 - 728
Journal Article