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1. Cinnamaldehyde Analogues as Potential Therapeutic Agents
by Chen, Bang-Jiao and Chen, Bang-Jiao and Fu, Chun-Sheng and Fu, Chun-Sheng and Li, Guo-Hui and Li, Guo-Hui and Wang, Xiao-Ning and Wang, Xiao-Ning and Lou, Hong-Xiang and Lou, Hong-Xiang and Ren, Dong-Mei and Ren, Dong-Mei and Shen, Tao and Shen, Tao
Mini reviews in medicinal chemistry, ISSN 1389-5575, 2017, Volume 17, Issue 1, pp. 33 - 43
Phytochemisty | Cinnamoyl | Cinnamaldehyde | Pharmacology | Synthesis | Cinnamaldehyde analogue | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Hypoglycemic Agents - therapeutic use | Neuroprotective Agents - therapeutic use | Acrolein - analogs & derivatives | Neuroprotective Agents - chemistry | Antineoplastic Agents - chemical synthesis | Humans | Anti-Infective Agents - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Antineoplastic Agents - therapeutic use | Hypoglycemic Agents - chemistry | Antineoplastic Agents - chemistry | Anti-Infective Agents - chemical synthesis | Acrolein - chemical synthesis | Neoplasms - drug therapy | Neuroprotective Agents - chemical synthesis | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Anti-Infective Agents - chemistry | Hypoglycemic Agents - chemical synthesis | Acrolein - therapeutic use | Molecular Structure | Acrolein - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis
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2. Full Text Synthesis and structure–activity relationship of N-(cinnamyl) chitosan analogs as antimicrobial agents
by Badawy, Mohamed E.I and Rabea, Entsar I
International journal of biological macromolecules, ISSN 0141-8130, 06/2013, Volume 57, pp. 185 - 192
Antifungal activity | N-(cinnamyl) chitosans | Antibacterial activity | Spore germination | NMR spectroscopy | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Applied | Polymer Science | Science & Technology | Acrolein - analogs & derivatives | Anti-Infective Agents - pharmacology | Spores, Fungal - growth & development | Anti-Infective Agents - chemical synthesis | Agrobacterium tumefaciens - growth & development | Chitosan - chemistry | Anti-Infective Agents - chemistry | Fungi - physiology | Mycelium - growth & development | Chitosan - pharmacology | Pectobacterium carotovorum - growth & development | Acrolein - chemistry | Chitosan - analogs & derivatives | Chitosan - chemical synthesis | Fungi | Schiff bases | Nuclear magnetic resonance spectroscopy | Chemical properties | Index Medicus
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3. Full Text Structure–activity analysis of 2′-modified cinnamaldehyde analogues as potential anticancer agents
by Gan, Fei Fei and Chua, Yee Shin and Scarmagnani, Silvia and Palaniappan, Puvithira and Franks, Mark and Poobalasingam, Thurka and Bradshaw, Tracey D and Westwell, Andrew D and Hagen, Thilo
Biochemical and biophysical research communications, ISSN 0006-291X, 2009, Volume 387, Issue 4, pp. 741 - 747
Anticancer drugs | Structure–activity analysis | Cinnamaldehydes | Michael acceptors | Apoptosis | Structure-activity analysis | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Acrolein - analogs & derivatives | Acrolein - pharmacology | Apoptosis - drug effects | Benzoates - chemistry | Humans | Antineoplastic Agents, Phytogenic - chemistry | Cell Line, Tumor - drug effects | Structure-Activity Relationship | Autophagy | Cinnamates - pharmacology | Proteasome Endopeptidase Complex - drug effects | Drug Design | Benzoates - pharmacology | Cinnamates - chemistry | Proteasome Endopeptidase Complex - metabolism | Acrolein - chemistry | Antineoplastic Agents, Phytogenic - pharmacology | Antimitotic agents | Cell research | Care and treatment | Heterocyclic compounds | Cell death | Pharmacy | Analysis | Antineoplastic agents | Cancer | Index Medicus
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4. Full Text Relationship between antimold activity and molecular structure of cinnamaldehyde analogues
by Zhang, Yuanyuan and Li, Shujun and Kong, Xianchao
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 03/2013, Volume 23, Issue 5, pp. 1358 - 1364
Cinnamaldehyde | Paecilomyces variotii | Antimold activity | Aspergillus niger | QSAR molding | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Acrolein - analogs & derivatives | Acrolein - pharmacology | Aspergillus niger - drug effects | Molecular Structure | Paecilomyces - drug effects | Acrolein - chemistry | Fungicides, Industrial - chemical synthesis | Fungicides, Industrial - chemistry | Fungicides, Industrial - pharmacology | Quantitative Structure-Activity Relationship | Acrolein - chemical synthesis | Forest management | Aldehydes | Heterocyclic compounds | Analysis | Index Medicus
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5. Full Text North American contact dermatitis group patch test results: 2011-2012
by Warshaw, Erin M and Maibach, Howard I and Taylor, James S and Sasseville, Denis and DeKoven, Joel G and Zirwas, Matthew J and Fransway, Anthony F and Mathias, Toby and Zug, Kathryn A and DeLeo, Vincent A and Fowler, Joseph F and Marks, James G and Pratt, Melanie D and Storrs, Frances J and Belsito, Donald V
Dermatitis, ISSN 1710-3568, 01/2015, Volume 26, Issue 1, pp. 49 - 59
Life Sciences & Biomedicine | Dermatology | Science & Technology | Acrolein - analogs & derivatives | Allergens - adverse effects | Prevalence | Humans | Middle Aged | Child, Preschool | Formaldehyde - adverse effects | Male | Thiazoles - adverse effects | Dermatitis, Occupational - etiology | Young Adult | Glutaral - adverse effects | Propylene Glycols - adverse effects | Methenamine - analogs & derivatives | Urea - analogs & derivatives | Aged, 80 and over | Adult | Female | Parabens - adverse effects | Child | Patch Tests | Lanolin - adverse effects | Hydantoins - adverse effects | Lanolin - analogs & derivatives | Dermatitis, Occupational - epidemiology | Dermatitis, Allergic Contact - epidemiology | Dermatitis, Allergic Contact - diagnosis | Dermatitis, Allergic Contact - etiology | Acrolein - adverse effects | Adolescent | Urea - adverse effects | Perfume - adverse effects | Aged | Methenamine - adverse effects | North America - epidemiology | Index Medicus
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6. Full Text Curcumin analog 1, 5-bis (2-trifluoromethylphenyl)-1, 4-pentadien-3-one exhibits enhanced ability on Nrf2 activation and protection against acrolein-induced ARPE-19 cell toxicity
by Li, Yuan and Zou, Xuan and Cao, Ke and Xu, Jie and Yue, Tingting and Dai, Fang and Zhou, Bo and Lu, Wuyuan and Feng, Zhihui and Liu, Jiankang
Toxicology and applied pharmacology, ISSN 0041-008X, 11/2013, Volume 272, Issue 3, pp. 726 - 735
Oxidative stress | Reactive oxygen species | Age-related macular degeneration | Mitochondrial membrane potential | Glutathione | Pharmacology & Pharmacy | Toxicology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Ophthalmology | Retinopathies | Cell Line | Cell Survival - drug effects | Retinal Pigment Epithelium - metabolism | Curcumin - analogs & derivatives | Humans | Oxidative Stress - physiology | Curcumin - pharmacology | Antioxidants - pharmacology | Cytoprotection - physiology | Dose-Response Relationship, Drug | NF-E2-Related Factor 2 - metabolism | Acrolein - toxicity | Cytoprotection - drug effects | Oxidative Stress - drug effects | Acrolein - antagonists & inhibitors | Cell Survival - physiology | Retinal Pigment Epithelium - drug effects | Macular degeneration | Eye diseases | Genetic transcription | Analysis | Cells | Index Medicus | OXIDATION | TRANSLOCATION | ANTIOXIDANTS | ACROLEIN | CURCUMIN | MITOCHONDRIA | BIOLOGICAL AVAILABILITY | TOXICITY | 60 APPLIED LIFE SCIENCES | TOBACCO SMOKES | DISEASES | GLUTATHIONE | ENZYMES | INFLAMMATION | RHODOPSIN | RETINA | ENZYME INDUCTION
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7. Full Text Structure based modification of chalcone analogue activates Nrf2 in the human retinal pigment epithelial cell line ARPE-19
by Cui, Yuting and Li, Yuan and Huang, Na and Xiong, Yue and Cao, Ruijun and Meng, Lingjie and Liu, Jiankang and Feng, Zhihui
Free radical biology & medicine, ISSN 0891-5849, 02/2020, Volume 148, pp. 52 - 59
Macular degeneration | Oxidative stress | Acrolein | Mitochondrial dysfunction | Nrf2 | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Index Medicus
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8. Full Text Identification of a role for a mouse sperm surface aldo‐keto reductase (AKR1B7) and its human analogue in the detoxification of the reactive aldehyde, acrolein
by Jagoe, W. N and Howe, K and O'Brien, S. C and Carroll, J
Andrologia, ISSN 0303-4569, 10/2013, Volume 45, Issue 5, pp. 326 - 331
Acrolein | MVDP | aldo‐keto reductase | detoxification | AKR1B7 | Aldo-keto reductase | Detoxification | Andrology | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Aldo-Keto Reductases | Inactivation, Metabolic | Animals | Acrolein - pharmacokinetics | Humans | Spermine - metabolism | Spermine - toxicity | Alcohol Oxidoreductases - metabolism | Aldehyde Reductase - metabolism | Male | Mice | Acrolein - metabolism | Spermatozoa | Index Medicus
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9. Full Text Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
by Macpherson, Lindsey J and Dubin, Adrienne E and Evans, Michael J and Marr, Felix and Schultz, Peter G and Cravatt, Benjamin F and Patapoutian, Ardem
Nature (London), ISSN 0028-0836, 02/2007, Volume 445, Issue 7127, pp. 541 - 545
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: nervous system and sense organs | Biological and medical sciences | Somesthesis and somesthetic pathways (proprioception, exteroception, nociception); interoception; electrolocation. Sensory receptors | Disulfides - metabolism | Acrolein - analogs & derivatives | Noxae - metabolism | Humans | Electric Conductivity | Pain - chemically induced | Acrolein - metabolism | Disulfides - chemistry | Noxae - pharmacology | Cysteine - metabolism | Transient Receptor Potential Channels - metabolism | Noxae - chemistry | Dithiothreitol - pharmacology | Acrolein - pharmacology | Plant Oils - pharmacology | Transient Receptor Potential Channels - chemistry | Ethyl Methanesulfonate - chemistry | Ethyl Methanesulfonate - metabolism | Cysteine - chemistry | Transient Receptor Potential Channels - agonists | Ethyl Methanesulfonate - analogs & derivatives | Mustard Plant - chemistry | Animals | Pain - physiopathology | Ethyl Methanesulfonate - pharmacology | Plant Oils - metabolism | Mice | Acrolein - chemistry | Mustard Plant - metabolism | Plant Oils - chemistry | Ion Channel Gating - drug effects | Neurology | Chemistry | Rodents | Spectrum analysis | Ions | Chemical reactions | Binding sites | Index Medicus
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10. Full Text Urinary biomarkers of oxidative status
by Il'yasova, Dora and Scarbrough, Peter and Spasojevic, Ivan
Clinica chimica acta, ISSN 0009-8981, 10/2012, Volume 413, Issue 19-20, pp. 1446 - 1453
F2-Isoprostanes | Oxidative stress | Allantoin | Dityrosine | Malondialdehyde | 8-oxodG | Life Sciences & Biomedicine | Medical Laboratory Technology | Science & Technology | F2-Isoprostanes - urine | Biomarkers - urine | Reactive Oxygen Species - metabolism | Uric Acid - metabolism | Deoxyguanosine - urine | Oxidation-Reduction | Oxidative Stress | Humans | Tyrosine - analogs & derivatives | Glycation End Products, Advanced - urine | Tyrosine - urine | DNA Damage | Lipid Peroxidation | Allantoin - urine | Deoxyguanosine - analogs & derivatives | Physiological aspects | Uric acid | Biological markers | Analysis | Index Medicus | Urine | Acrolein | Reactive Oxygen Species | Biomarkers
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