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Neuroscience Letters, ISSN 0304-3940, 02/2013, Volume 535, Issue 1, pp. 146 - 151
► CA/CAPE attenuated acrolein-induced neurotoxicity and neuronal damage. ► CA/CAPE improved ROS, GSH and MAPKs damaged by acrolein. ► CA/CAPE modulated key... 
Acrolein | Oxidative stress | Alzheimer's disease | Caffeic acid | ALZHEIMERS-DISEASE BRAIN | INHIBITION | LIPID-PEROXIDATION | MECHANISM | TOXICITY | MILD COGNITIVE IMPAIRMENT | EXPRESSION | NEUROSCIENCES | Reactive Oxygen Species - metabolism | Oxidative Stress | Glutathione - metabolism | Phenylethyl Alcohol - analogs & derivatives | Caffeic Acids - pharmacology | Glycogen Synthase Kinase 3 beta | Neurons - cytology | Hippocampus - drug effects | Neuroprotective Agents - pharmacology | Acrolein - toxicity | Membrane Proteins - metabolism | Neurons - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | Cell Survival - drug effects | ADAM10 Protein | Antioxidants - pharmacology | Glycogen Synthase Kinase 3 - metabolism | Hippocampus - cytology | Phenylethyl Alcohol - pharmacology | ADAM Proteins - metabolism | Amyloid Precursor Protein Secretases - metabolism | Animals | MAP Kinase Signaling System - drug effects | Aspartic Acid Endopeptidases - metabolism | Mice | Enzymes | Synthesis | Peptides | Glycogen | Amyloid beta-protein | Medicine, Chinese | Protein kinases | Index Medicus | Acrolein/toxicity | Hippocampus/cytology | Phenylethyl Alcohol/analogs & derivatives | Neurons and Cognition | Neurobiology | Neurons/drug effects | Proto-Oncogene Proteins c-akt/metabolism | Cell Survival/drug effects | Aspartic Acid Endopeptidases/metabolism | Glycogen Synthase Kinase 3/metabolism | Life Sciences | Secretases/metabolism | Hippocampus/drug effects | ADAM Proteins/mCetabolismCell Line | Reactive Oxygen Species/metabolism | Amyloid Precursor Protein | Antioxidants/pharmacology | Neurons/cytology | Neuroprotective Agents/pharmacology | Glutathione/metabolism | MAP Kinase Signaling System/drug effects | Membrane Proteins/metabolism | Caffeic Acids/pharmacology
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 2010, Volume 21, Issue 11, pp. 1089 - 1098
Journal Article
Gastroenterology, ISSN 0016-5085, 2011, Volume 141, Issue 2, pp. 565 - 575.e4
Background & Aims Transient receptor potential ankyrin (TRPA) 1, an excitatory ion channel expressed by sensory neurons, mediates somatic and visceral pain in... 
Gastroenterology and Hepatology | TRP Channels | Enteric Nervous System | Motility | OXIDATIVE STRESS | ACTIVATION | PROTEIN | TRPA1 | ENTERIC NERVOUS-SYSTEM | SENSORY NEURONS | EXPERIMENTAL COLITIS | CHANNEL | INFLAMMATORY PAIN | GASTROENTEROLOGY & HEPATOLOGY | PROSTAGLANDIN D-2 | Ganglia - metabolism | Colon - drug effects | Ileum - metabolism | Colon - innervation | Male | RNA, Messenger - metabolism | Muscle, Smooth - drug effects | Ileum - drug effects | Duodenum - metabolism | Muscle, Smooth - physiology | Stomach - innervation | Transient Receptor Potential Channels - metabolism | Isothiocyanates - pharmacology | Ileum - innervation | Neurons, Afferent - drug effects | Muscle, Smooth - innervation | Duodenum - physiology | Reverse Transcriptase Polymerase Chain Reaction | Cecum - drug effects | Colon - metabolism | Mice, Knockout | Motor Neurons - metabolism | Interneurons - metabolism | Muscle Contraction - drug effects | Muscle Contraction - physiology | Mice | Neurons, Afferent - metabolism | Duodenum - innervation | Acrolein - analogs & derivatives | Intestinal Mucosa - metabolism | Epithelial Cells - metabolism | Colon - physiology | Gastrointestinal Motility - drug effects | Gastrointestinal Motility - physiology | Stomach - physiology | Substance P - pharmacology | Stomach - metabolism | Cecum - physiology | Cecum - metabolism | Aldehydes - pharmacology | Cecum - innervation | Female | Transient Receptor Potential Channels - physiology | Stomach - drug effects | Motor Neurons - drug effects | Acrolein - pharmacology | Mice, Inbred C57BL | Interneurons - drug effects | Transient Receptor Potential Channels - agonists | Carbachol - pharmacology | Animals | TRPA1 Cation Channel | Fluorescent Antibody Technique | Gastric Emptying - physiology | Ileum - physiology | Duodenum - drug effects | Physiological aspects | Neurons | Gastrointestinal diseases | Nitric oxide | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 07/2007, Volume 117, Issue 7, pp. 1979 - 1987
Journal Article
Nature, ISSN 0028-0836, 02/2007, Volume 445, Issue 7127, pp. 541 - 545
Journal Article
Diabetes, ISSN 0012-1797, 11/2011, Volume 60, Issue 11, pp. 3055 - 3066
OBJECTIVE-To determine whether dietary compounds targeting NFE2-related factor 2 (Nrf2) activation can be used to attenuate renal damage and preserve renal... 
PERFORMANCE LIQUID-CHROMATOGRAPHY | GROWTH-FACTOR-BETA | OXIDATIVE STRESS | TGF-BETA | GLOMERULAR HYPERTROPHY | CELLS IN-VITRO | BARDOXOLONE METHYL | KIDNEY-FUNCTION | ENDOCRINOLOGY & METABOLISM | SULFORAPHANE PROTECTS | HIGH-DOSE THIAMINE | Acrolein - analogs & derivatives | Reactive Oxygen Species - metabolism | Kidney - pathology | Humans | Transforming Growth Factor beta1 - metabolism | NF-E2-Related Factor 2 - agonists | Mesangial Cells - drug effects | Dose-Response Relationship, Drug | Diabetic Nephropathies - physiopathology | RNA Interference | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Thiocyanates - pharmacology | NF-E2-Related Factor 2 - genetics | Thiocyanates - administration & dosage | Diabetic Nephropathies - prevention & control | Isothiocyanates | Extracellular Matrix Proteins - metabolism | Kidney - physiopathology | Acrolein - pharmacology | Thiocyanates - therapeutic use | Diabetic Nephropathies - pathology | Kidney - drug effects | Acrolein - administration & dosage | Diabetic Nephropathies - metabolism | Mice, Inbred C57BL | Cells, Cultured | Mesangial Cells - metabolism | Random Allocation | Mice, Knockout | Animals | NF-E2-Related Factor 2 - metabolism | Mesangial Cells - pathology | Acrolein - therapeutic use | Cell Proliferation - drug effects | Mice | RNA, Small Interfering | Oxidative Stress - drug effects | Care and treatment | Streptozocin | Diabetic nephropathies | Weight loss | Development and progression | Research | Health aspects | Risk factors | Index Medicus | Abridged Index Medicus | Pharmacology and Therapeutics
Journal Article
Experimental Biology and Medicine, ISSN 1535-3702, 4/2008, Volume 233, Issue 4, pp. 463 - 474
Journal Article