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Nature Immunology, ISSN 1529-2908, 11/2012, Volume 13, Issue 11, pp. 1072 - 1082
Hematopoietic stem and progenitor cells (HSPCs) are regulated by various bone marrow stromal cell types. Here we identified rare activated bone marrow... 
PROGENITOR CELLS | OXIDATIVE STRESS | MICROENVIRONMENT | MYELOPOIESIS | RECEPTOR LIGANDS | NICHE | STEM-CELL | IMMUNOLOGY | STROMAL CELLS | RECONSTITUTION | PROSTAGLANDIN-E2 | Cell Communication - immunology | Gamma Rays | Bone Marrow - immunology | Mesenchymal Stromal Cells - radiation effects | Reactive Oxygen Species - metabolism | Dinoprostone - biosynthesis | Monocytes - cytology | Monocytes - radiation effects | Cell Survival - genetics | Bone Marrow - radiation effects | Monocytes - immunology | Actins - immunology | Dinoprostone - immunology | Cell Movement - genetics | Proto-Oncogene Proteins c-akt - genetics | Actins - genetics | Mesenchymal Stromal Cells - immunology | Cell Movement - immunology | Signal Transduction - immunology | Hematopoietic Stem Cells - immunology | Mesenchymal Stromal Cells - cytology | Chemokine CXCL12 - genetics | Cyclooxygenase 2 - genetics | Reactive Oxygen Species - immunology | Bone Marrow - metabolism | Macrophages - radiation effects | Signal Transduction - radiation effects | Cyclooxygenase 2 - immunology | Hematopoietic Stem Cells - radiation effects | Chemokine CXCL12 - immunology | Macrophages - immunology | Gene Expression Regulation - immunology | Signal Transduction - genetics | Cell Communication - genetics | Macrophages - cytology | Cell Survival - immunology | Cell Survival - radiation effects | Animals | Proto-Oncogene Proteins c-akt - immunology | Hematopoietic Stem Cells - cytology | Gene Expression Regulation - radiation effects | Mice
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 10/2013, Volume 15, Issue 5, pp. R168 - R168
Introduction: B lymphocytes might play a pathogenic role in dermal fibrosis in systemic sclerosis (SSc). B-cell activating factor (BAFF), a key cytokine for... 
BAFF | ADHESION | SCLERODERMA | TIMP-1 | AUTOIMMUNITY | SKIN FIBROSIS | DEPLETION | MECHANISMS | RHEUMATOLOGY | INTERLEUKIN-6 | IL-6 | Gene Expression - drug effects | Chemokine CCL2 - immunology | Skin - metabolism | Antibodies, Anti-Idiotypic - pharmacology | Coculture Techniques | Humans | Transforming Growth Factor beta1 - metabolism | Actins - metabolism | Matrix Metalloproteinase 9 - immunology | Fibrosis - metabolism | Actins - immunology | Immunoglobulin M - immunology | Actins - genetics | Transforming Growth Factor beta1 - immunology | Matrix Metalloproteinase 9 - genetics | Fibrosis - immunology | Gene Expression - immunology | B-Cell Activating Factor - immunology | Chemokine CCL2 - metabolism | Collagen - genetics | Interleukin-6 - metabolism | B-Lymphocytes - metabolism | Skin - pathology | Fibroblasts - metabolism | Skin - immunology | B-Lymphocytes - cytology | Fibrosis - genetics | Enzyme-Linked Immunosorbent Assay | Collagen - immunology | Scleroderma, Systemic - metabolism | Cells, Cultured | Scleroderma, Systemic - genetics | Antibodies, Anti-Idiotypic - immunology | Scleroderma, Systemic - immunology | Fibroblasts - pathology | Reverse Transcriptase Polymerase Chain Reaction | Muscle, Smooth - chemistry | Collagen - metabolism | Tissue Inhibitor of Metalloproteinase-1 - genetics | B-Cell Activating Factor - metabolism | B-Lymphocytes - immunology | Interleukin-6 - immunology | Fibroblasts - immunology | B-Cell Activating Factor - pharmacology | Tissue Inhibitor of Metalloproteinase-1 - immunology | Computer software industry | Cytokines | RNA | Systemic scleroderma | Scleroderma (Disease) | Fibroblasts | Bone morphogenetic proteins | B cells | Transforming growth factors | Blood donors | Life Sciences | Human health and pathology | Rhumatology and musculoskeletal system
Journal Article
Immunity, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 461 - 474
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e48854
Cell-mediated transmission and dissemination of sexually-acquired human immunodeficiency virus 1 (HIV-1) in the host involves the migration of immature... 
SLIT | PROTEIN | REPELLENT | HIV | ANGIOGENESIS | CHEMOTAXIS | MULTIDISCIPLINARY SCIENCES | GUIDANCE | RECEPTORS | ROBO | MIDLINE | Paxillin - metabolism | Proto-Oncogene Proteins pp60(c-src) - immunology | Pseudopodia - immunology | Human Umbilical Vein Endothelial Cells - metabolism | Dendritic Cells - immunology | Humans | Actins - metabolism | Human Umbilical Vein Endothelial Cells - immunology | cdc42 GTP-Binding Protein - metabolism | Paxillin - immunology | Actins - immunology | HIV Envelope Protein gp120 - metabolism | Cell Movement - immunology | HIV Envelope Protein gp120 - immunology | Intercellular Signaling Peptides and Proteins - metabolism | Signal Transduction - immunology | rac1 GTP-Binding Protein - immunology | Actin-Related Protein 2-3 Complex - metabolism | Focal Adhesion Kinase 2 - metabolism | RNA Interference | cdc42 GTP-Binding Protein - immunology | Wiskott-Aldrich Syndrome Protein - metabolism | Microfilament Proteins - metabolism | Receptors, Immunologic - immunology | Microfilament Proteins - genetics | Dendritic Cells - metabolism | Nerve Tissue Proteins - immunology | Cells, Cultured | Protein Binding - immunology | Blotting, Western | Actin-Related Protein 2-3 Complex - immunology | Nerve Tissue Proteins - metabolism | Microscopy, Confocal | Wiskott-Aldrich Syndrome Protein - immunology | Proto-Oncogene Proteins pp60(c-src) - metabolism | Microfilament Proteins - immunology | Intercellular Signaling Peptides and Proteins - immunology | Receptors, Immunologic - metabolism | rac1 GTP-Binding Protein - metabolism | Focal Adhesion Kinase 2 - immunology | Dendritic cells | HIV (Viruses) | Muscle proteins | Actin | Protein binding | Cdc42 protein | Motility | Leukocyte migration | Mucosa | Viruses | Smooth muscle | Kinases | Tissues | Medical schools | Cell adhesion & migration | Proteins | Angiogenesis | Sexually transmitted diseases | Human immunodeficiency virus--HIV | Inhibition | Sequestering | Localization | Wiskott-Aldrich syndrome | LSP1 protein | Glycoprotein | Envelope protein | Rac1 protein | White blood cells | Medicine | Actin-related protein 2 | Signaling | Disease transmission | Ligands | Paxillin | Glycoprotein gp120 | Cell migration | Human immunodeficiency virus
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2007, Volume 179, Issue 10, pp. 6456 - 6467
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 12, pp. 2165 - 2182
DNAM-1 (CD226) is an activating receptor expressed on natural killer (NK) cells, CD8(+) T cells, and other immune cells. Upon recognition of its ligands, CD155... 
HEMATOPOIETIC-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | NATURAL-KILLER-CELLS | ADHESION MOLECULE | GRANULE POLARIZATION | RECEPTOR | GRB2 | IMMUNOLOGY | PROTEINS | CYTOTOXICITY | ADAPTER SAP | SH3 DOMAIN | GRB2 Adaptor Protein - immunology | Calcium - metabolism | Humans | Actins - metabolism | Calcium - immunology | Cell Survival - genetics | Immunoblotting | Extracellular Signal-Regulated MAP Kinases - metabolism | Actins - immunology | Enzyme Activation - immunology | Extracellular Signal-Regulated MAP Kinases - immunology | Signal Transduction - immunology | Lymphocyte Activation - genetics | Lymphocyte Activation - immunology | RNA Interference | GRB2 Adaptor Protein - genetics | Killer Cells, Natural - immunology | Proto-Oncogene Proteins c-akt - metabolism | Cytokines - immunology | Cell Line | Antigens, Differentiation, T-Lymphocyte - immunology | Cytokines - metabolism | Mice, Inbred C57BL | Antigens, Differentiation, T-Lymphocyte - metabolism | Polymerization | Signal Transduction - genetics | Cell Survival - immunology | Protein Binding - immunology | Mice, Knockout | Microscopy, Confocal | Animals | Proto-Oncogene Proteins c-akt - immunology | Amino Acid Motifs - immunology | Antigens, Differentiation, T-Lymphocyte - genetics | Cell Line, Tumor | Killer Cells, Natural - metabolism | Amino Acid Motifs - genetics | GRB2 Adaptor Protein - metabolism
Journal Article
Blood, ISSN 0006-4971, 05/2007, Volume 109, Issue 9, pp. 3776 - 3785
Natural killer (NK) cells directly lyse tumor or viral-infected cells but also an important role for NK cell cytotoxicity in regulating the extent of immune... 
MEDIATED CYTOLYSIS | DENDRITIC CELLS | CYTOTOXICITY RECEPTORS | NK-CELL | ACTIVATING RECEPTORS | NKG2D RECEPTOR | IMMUNOLOGICAL SYNAPSE | HEMATOLOGY | UL16-BINDING PROTEIN | HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS | T-CELLS | Antigens, CD - immunology | Cell Communication - immunology | Membrane Glycoproteins - metabolism | Natural Cytotoxicity Triggering Receptor 3 | Coculture Techniques | Humans | Actins - metabolism | Intracellular Signaling Peptides and Proteins - immunology | Intracellular Signaling Peptides and Proteins - metabolism | Actins - immunology | Antigens, CD - metabolism | Histocompatibility Antigens Class I - metabolism | Lymphocyte Activation - immunology | Immunity, Cellular - drug effects | Receptors, Immunologic - biosynthesis | Receptors, Natural Killer Cell | Killer Cells, Natural - immunology | Membrane Glycoproteins - immunology | Receptors, Immunologic - immunology | Macrophages - immunology | Cytokines - immunology | NK Cell Lectin-Like Receptor Subfamily K | Cells, Cultured | Cytokines - secretion | Histocompatibility Antigens Class I - immunology | Membrane Proteins - immunology | Signaling Lymphocytic Activation Molecule Family | Macrophages - metabolism | Membrane Proteins - biosynthesis | Lymphocyte Activation - drug effects | Cell Communication - drug effects | Lipopolysaccharides - pharmacology | Ligands | Cell Proliferation - drug effects | Killer Cells, Natural - metabolism | Receptors, Immunologic - metabolism | Killer Cells, Natural | Cell Proliferation | Cytokines | Lymphocyte Activation | Histocompatibility Antigens Class I | Actins | Intracellular Signaling Peptides and Proteins | Cell Communication | Macrophages | Lipopolysaccharides | Membrane Proteins | Life Sciences | Immunology | Receptors, Immunologic | Membrane Glycoproteins | Immunity, Cellular | Antigens, CD
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2017, Volume 114, Issue 44, pp. E9338 - E9345
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2008, Volume 181, Issue 8, pp. 5587 - 5597
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2013, Volume 110, Issue 43, pp. 17253 - 17258
Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue microenvironment. Although much is known about how soluble factors... 
Phenotypes | Cell growth | Cytokines | Stem cells | Cell lines | Actins | Physiological regulation | Macrophages | Endothelial cells | Cells | FIBER | MATRIX | ACTIVATION | ACTIN | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DIFFERENTIATION | SCAFFOLDS | CULTURE | MESENCHYMAL STEM-CELLS | Mannose-Binding Lectins - metabolism | Arginase - metabolism | Lectins, C-Type - immunology | Cell Shape - immunology | Myosin-Light-Chain Kinase - antagonists & inhibitors | Cytochalasin D - pharmacology | Lectins, C-Type - metabolism | Arginase - immunology | Interleukin-4 - pharmacology | Flow Cytometry | Doxorubicin - analogs & derivatives | Inflammation Mediators - metabolism | Female | Immunophenotyping - methods | Cell Polarity - drug effects | Doxorubicin - metabolism | Macrophages - immunology | Cytokines - immunology | Amides - pharmacology | Biomarkers - metabolism | Inflammation Mediators - immunology | Cell Polarity - immunology | Cytokines - metabolism | Myosin-Light-Chain Kinase - metabolism | Mice, Inbred C57BL | Biomarkers - analysis | Cells, Cultured | Receptors, Cell Surface - metabolism | Macrophages - cytology | Interleukin-13 - pharmacology | Receptors, Cell Surface - immunology | Azepines - pharmacology | Cell Shape - drug effects | Macrophages - metabolism | Animals | Mannose-Binding Lectins - immunology | Lipopolysaccharides - pharmacology | Mice | Pyridines - pharmacology | Doxorubicin - immunology | Interferon-gamma - pharmacology | Microscopy, Fluorescence | Physiological aspects | Microbial genetics | Phenotype | Genetic aspects | Research | Geometry | Genotype & phenotype | Morphology | Biological Sciences | Physical Sciences
Journal Article