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02/2014
Objective: Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by reduced serum level of IgG, IgA or IgM and recurrent bacterial... 
Activation-Induced Cytidine Deaminase | Common Variable Immunodeficiency | AICDA Protein | Class Switching
Web Resource
Nature Immunology, ISSN 1529-2908, 01/2011, Volume 12, Issue 1, pp. 62 - 69
Journal Article
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 11/2015, Volume 43, Issue 5, pp. 884 - 895
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2008, Volume 3, Issue 8, p. e3033
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2015, Volume 112, Issue 18, pp. 5791 - 5796
Activation-induced cytidine deaminase (AID) is essential for antibody class switch recombination (CSR) and somatic hypermutation (SHM). AID originally was... 
Activation-induced cytidine deaminase | B cell | Somatic hypermutation | Class switch recombination | IgH | APOBEC-1 COMPLEMENTATION FACTOR | activation-induced cytidine deaminase | MULTIDISCIPLINARY SCIENCES | B MESSENGER-RNA | EDITING ENZYME | BINDING PROTEIN | class switch recombination | somatic hypermutation | C-TERMINAL REGION | KH DOMAINS | CLASS-SWITCH RECOMBINATION | MOLECULAR-CLONING | AID | Protein Structure, Tertiary | Somatic Hypermutation, Immunoglobulin | Cell Separation | Humans | Heterogeneous-Nuclear Ribonucleoprotein L - chemistry | Immunoglobulin Heavy Chains - chemistry | Heterogeneous-Nuclear Ribonucleoprotein K - chemistry | Genetic Complementation Test | DNA - chemistry | Flow Cytometry | APOBEC-1 Deaminase | Recombination, Genetic | Cytidine Deaminase - metabolism | Heterogeneous-Nuclear Ribonucleoproteins - chemistry | HEK293 Cells | Cell Line, Tumor | Protein Binding | Mutation | Cytidine Deaminase - chemistry | Immunoglobulin Class Switching | Proto-Oncogene Proteins c-bcl-2 - genetics | RNA-Binding Proteins - metabolism | Immunoglobulin A - chemistry | RNA, Small Interfering - metabolism | Physiological aspects | Messenger RNA | Observations | Genetic recombination | DNA damage | Enzymes | Immunoglobulins | Polypeptides | Ribonucleic acid--RNA | Apolipoproteins | Deoxyribonucleic acid--DNA | Biological Sciences
Journal Article
mBio, ISSN 2150-7511, 08/2019, Volume 10, Issue 4
Complex human-pathogenic retroviruses cause high morbidity and mortality worldwide, but resist antiviral drugs and vaccine development due to evasion of the... 
IMMUNOGLOBULIN SOMATIC HYPERMUTATION | activation-induced cytidine deaminase | mouse mammary tumor virus | REVERSE TRANSCRIPTION | ENZYME APOBEC3G | MICROBIOLOGY | GERMINAL CENTER | Apobec3 | retroviruses | MAMMARY-TUMOR VIRUS | B LEUKEMOGENIC VIRUS | VIF PROTEIN | IN-VIVO | STRAND DNA BREAKS | AID | AID inhibitor
Journal Article