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1. Full Text Treatment of human embryos with the TGF  inhibitor SB431542 increases epiblast proliferation and permits successful human embryonic stem cell derivation
by Van der Jeught, M and Heindryckx, B and O'Leary, T and Duggal, G and Ghimire, S and Lierman, S and Van Roy, N and Chuva de Sousa Lopes, S. M and Deroo, T and Deforce, D and De Sutter, P
Human reproduction (Oxford), ISSN 0268-1161, 01/2014, Volume 29, Issue 1, pp. 41 - 48
Activin
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2. Full Text New insights into the mechanisms of activin action and inhibition
by Walton, Kelly L and Makanji, Yogeshwar and Harrison, Craig A
Molecular and cellular endocrinology, ISSN 0303-7207, 08/2012, Volume 359, Issue 1-2, pp. 2 - 12
Prodomain | Follistatin | Activin | Betaglycan | Transforming growth factor-β | Inhibin | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Protein Structure, Tertiary | Activin Receptors, Type II - metabolism | Signal Transduction | Humans | Activins - physiology | Proteoglycans - metabolism | Activin Receptors, Type I - metabolism | Activins - metabolism | Receptors, Transforming Growth Factor beta - physiology | Amino Acid Motifs | Protein Precursors - metabolism | Animals | Inhibins - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Protein Precursors - physiology | Proteoglycans - physiology | Protein Binding | Activin Receptors, Type I - physiology | Activin Receptors, Type II - physiology | Activin Receptors, Type II - chemistry | Inhibins - physiology | Activins - chemistry | Index Medicus | Binding | Cellular | Receptors | Proteoglycans | Precursors | Kinases | Sulfates | Knots
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3. Full Text MicroRNA-145 suppresses mouse granulosa cell proliferation by targeting activin receptor IB
by Yan, Guijun and Zhang, Lianxiao and Fang, Ting and Zhang, Qun and Wu, Shaogen and Jiang, Yue and Sun, Haixiang and Hu, Yali
FEBS letters, ISSN 0014-5793, 09/2012, Volume 586, Issue 19, pp. 3263 - 3270
Activin receptor IB | Granulosa cell | Smad | Proliferation | MicroRNA-145 | 3′-untranslated region | activin receptor typeIIA | estrogen receptor-α | premature ovarian failure | OCT4 | CCND2 | integrin, beta-8 | octamer-binding transcription factor-4 | TGF-β | ITGB8 | FSH | activin receptor typeIA | activin receptor typeIB | SOX9 | bone morphogenetic proteins | Sma and Mad related family | follicle-stimulating hormone | POF | 3′-UTR | ACVRIIB | luteinizing hormone | mouse granulosa cells | ACVRIIA | BMPs | SRY-related high mobility group-box gene-9 | activin receptor typeIIB | ACVRIB | growth differentiation factor-9 | transforming growth factor-β | ACVRIA | mGCs | cyclin D2 | LH | GDF-9 | ER-alpha | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cyclin D2 - genetics | Cyclin D2 - metabolism | Phosphorylation | Humans | Activins - metabolism | MicroRNAs - metabolism | RNA, Messenger - metabolism | Granulosa Cells - drug effects | Granulosa Cells - metabolism | Base Sequence | HEK293 Cells | Female | 3' Untranslated Regions | Signal Transduction | RNA, Messenger - genetics | Cells, Cultured | Smad2 Protein - metabolism | Activin Receptors, Type I - metabolism | Activin Receptors, Type I - genetics | Mice, Inbred ICR | Animals | Activins - pharmacology | Cell Proliferation - drug effects | Mice | MicroRNAs - genetics | Granulosa Cells - cytology | Follicle-stimulating hormone | MicroRNA | Genes | Luteinizing hormone | Bone morphogenetic proteins | Genetic transcription | Transforming growth factors | Integrins | Index Medicus
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4. Full Text Transforming growth factor-β family ligands can function as antagonists by competing for type II receptor binding
by Aykul, Senem and Martinez-Hackert, Erik
The Journal of biological chemistry, ISSN 0021-9258, 05/2016, Volume 291, Issue 20, pp. 10792 - 10804
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Binding, Competitive | Recombinant Proteins - metabolism | Activin Receptors, Type II - metabolism | Humans | Activins - antagonists & inhibitors | Activin Receptors, Type II - antagonists & inhibitors | Activins - metabolism | Bone Morphogenetic Protein Receptors, Type II - metabolism | Hep G2 Cells | Bone Morphogenetic Proteins - metabolism | Growth Differentiation Factors - metabolism | Activins - pharmacology | Signal Transduction - drug effects | Bone Morphogenetic Protein 2 - metabolism | Follistatin - pharmacology | Bone Morphogenetic Protein 7 - metabolism | Cell Line, Tumor | Bone Morphogenetic Protein Receptors, Type II - antagonists & inhibitors | Ligands | Growth Differentiation Factor 2 | Transforming Growth Factor beta - metabolism | Index Medicus | inhibition mechanism | signaling | Signal Transduction | activin | transforming growth factor β (TGF-B) | bone morphogenetic protein (BMP) | receptor tyrosine kinase
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5. Full Text Insight into Molecular Mechanism for Activin A-Induced Bone Morphogenetic Protein Signaling
by Xie, Chen and Jiang, Wenjuan and Lacroix, Jerome J and Luo, Yun and Hao, Jijun
International journal of molecular sciences, ISSN 1422-0067, 09/2020, Volume 21, Issue 18, p. 6498
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Activin Receptors, Type II - metabolism | Cell Line | Phosphorylation | Bone Morphogenetic Protein Receptors, Type II - genetics | Bone Morphogenetic Proteins - physiology | Gene Expression Regulation - genetics | Humans | Activins - physiology | Bone Morphogenetic Protein Receptors, Type I - genetics | Activin Receptors, Type I - metabolism | Activins - metabolism | Signal Transduction - genetics | Activin Receptors, Type I - genetics | Hep G2 Cells | Bone Morphogenetic Proteins - metabolism | Animals | Activin Receptors, Type II - genetics | HEK293 Cells | Signal Transduction - physiology | Mice | Ossification, Heterotopic - genetics | Cell Differentiation - physiology | Transforming Growth Factor beta - metabolism | Proteins | Signaling | Signal transduction | Bone morphogenetic protein 4 | Receptors | Ligands | Bone morphogenetic proteins | Mutation | Myositis ossificans | Kinases | Activin | Index Medicus | BMP | ALK2 | Fibrodysplasia Ossificans Progressiva | activin A | FKBP12
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6. Full Text The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva
by Alessi Wolken, Dana M and Idone, Vincent and Hatsell, Sarah J and Yu, Paul B and Economides, Aris N
Bone (New York, N.Y.), ISSN 8756-3282, 2017, Volume 109, pp. 210 - 217
Orthopedics | ACVR1 | Activin A | Anti-Activin antibody | Progenitor cells | Fibrodysplasia Ossificans Progressiva | Heterotopic Ossification | Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Myositis Ossificans - metabolism | Humans | Activin Receptors, Type I - metabolism | Activins - metabolism | Signal Transduction - genetics | Stem Cells - cytology | Mutation - genetics | Stem Cells - metabolism | Activin Receptors, Type I - genetics | Ossification, Heterotopic - metabolism | Myositis Ossificans - genetics | Signal Transduction - physiology | Activins - genetics | Ossification, Heterotopic - genetics | Monoclonal antibodies | Muscles | Index Medicus
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7. Full Text Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-alpha-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2
by Mitrofan, Claudia-Gabriela and Appleby, Sarah L and Nash, Gerard B and Mallat, Ziad and Chilvers, Edwin R and Upton, Paul D and Morrell, Nicholas W
The Journal of biological chemistry, ISSN 0021-9258, 08/2017, Volume 292, Issue 33, pp. 13714 - 13726
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Activin Receptors, Type I - antagonists & inhibitors | Endothelium, Vascular - cytology | Tumor Necrosis Factor-alpha - metabolism | Activin Receptors, Type II - metabolism | Monocytes - cytology | Humans | Activin Receptors, Type II - antagonists & inhibitors | Endothelium, Vascular - drug effects | Monocytes - metabolism | Monocytes - immunology | Tumor Necrosis Factor-alpha - agonists | Bone Morphogenetic Proteins - metabolism | Protein Processing, Post-Translational - drug effects | RNA Interference | E-Selectin - genetics | Aorta | Vascular Cell Adhesion Molecule-1 - genetics | Phosphorylation - drug effects | Growth Differentiation Factor 2 | Endothelium, Vascular - immunology | Pyrazoles - pharmacology | Cells, Cultured | Activin Receptors, Type I - metabolism | E-Selectin - metabolism | Pyrimidines - pharmacology | Cell Adhesion - drug effects | Activin Receptors, Type I - genetics | Vascular Cell Adhesion Molecule-1 - chemistry | Monocytes - drug effects | Up-Regulation - drug effects | Growth Differentiation Factors - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Intercellular Adhesion Molecule-1 - chemistry | Signal Transduction - drug effects | Endothelium, Vascular - metabolism | Intercellular Adhesion Molecule-1 - genetics | Activin Receptors, Type II - genetics | E-Selectin - chemistry | Protein Kinase Inhibitors - pharmacology | Kinetics | Vascular Cell Adhesion Molecule-1 - metabolism | Index Medicus | atherosclerosis | monocyte | SMAD transcription factor | bone morphogenetic protein (BMP) | endothelial cell | Cell Biology
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8. Full Text Ulipristal Acetate Modulates the Expression and Functions of Activin A in Leiomyoma Cells
by Ciarmela, Pasquapina and Carrarelli, Patrizia and Islam, Md Soriful and Janjusevic, Milijana and Zupi, Errico and Tosti, Claudia and Castellucci, Mario and Petraglia, Felice
Reproductive sciences (Thousand Oaks, Calif.), ISSN 1933-7191, 9/2014, Volume 21, Issue 9, pp. 1120 - 1125
ulipristal acetate | activin | fibronectin | follistatin | activin receptors | uterine fibroids | VEGF-A | uterine leiomyoma | Life Sciences & Biomedicine | Obstetrics & Gynecology | Reproductive Biology | Science & Technology | Uterine Neoplasms - metabolism | Norpregnadienes - therapeutic use | Humans | Middle Aged | Activins - antagonists & inhibitors | Activins - physiology | Gene Expression Regulation, Neoplastic | Leiomyoma - metabolism | Norpregnadienes - pharmacology | Leiomyoma - drug therapy | Uterine Neoplasms - drug therapy | Activins - biosynthesis | Adult | Female | Tumor Cells, Cultured | Index Medicus
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