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The Journal of clinical investigation, ISSN 0021-9738, 2013, Volume 123, Issue 9, pp. 4023 - 4035
Journal Article
Journal Article
Kidney international, ISSN 0085-2538, 2012, Volume 81, Issue 10, pp. 942 - 948
Despite the availability of renal replacement therapy, acute kidney injury (AKI) is associated with high mortality and morbidity... 
acute kidney injury | extrarenal complications | inflammation | pathophysiology | Inflammation | Pathophysiology | Extrarenal complications | Acute kidney injury | ISCHEMIA/REPERFUSION INJURY | MECHANICAL VENTILATION | ACUTE LUNG INJURY | ACUTE-RENAL-FAILURE | BILATERAL-NEPHRECTOMY | INTENSIVE-CARE | RESPIRATORY-DISTRESS-SYNDROME | ISCHEMIA-REPERFUSION INJURY | UROLOGY & NEPHROLOGY | CONGESTIVE-HEART-FAILURE | CRITICALLY-ILL PATIENTS | Brain Diseases - metabolism | Liver - pathology | Lung Diseases - metabolism | Reactive Oxygen Species - metabolism | Heart Diseases - metabolism | Kidney - pathology | Oxidative Stress | Humans | Liver Diseases - pathology | Liver - physiopathology | Brain Diseases - physiopathology | Lung Diseases - etiology | Brain - metabolism | Kidney - metabolism | Acute Kidney Injury - complications | Liver Diseases - etiology | Myocardium - metabolism | Inflammation Mediators - metabolism | Lung - metabolism | Brain Diseases - etiology | Kidney - physiopathology | Lung - pathology | Signal Transduction | Acute Kidney Injury - pathology | Heart Diseases - physiopathology | Brain - physiopathology | Liver - metabolism | Myocardium - pathology | Lung - physiopathology | Acute Kidney Injury - physiopathology | Heart Diseases - etiology | Animals | Brain Diseases - pathology | Brain - pathology | Lung Diseases - physiopathology | Liver Diseases - physiopathology | Lung Diseases - pathology | Acute Kidney Injury - metabolism | Liver Diseases - metabolism | Heart Diseases - pathology | Apoptosis
Journal Article
American Journal of Pathology, ISSN 0002-9440, 05/2009, Volume 174, Issue 5, pp. 1663 - 1674
Hypoxia-inducible transcription factors (HIFs) play important roles in the response of the kidney to systemic and regional hypoxia... 
OXYGEN | CELLS | DOMAIN PROTEINS | ERYTHROPOIETIN | MESSENGER-RNA | HYPOXIA-INDUCIBLE-FACTOR | ACUTE-RENAL-FAILURE | INDUCTION | PATHOLOGY | UP-REGULATION | FACTOR-ALPHA | Fibroblasts - enzymology | Prognosis | Homeodomain Proteins - metabolism | Kidney - enzymology | Podocytes - enzymology | Male | Gene Expression Regulation, Enzymologic - physiology | RNA, Messenger - metabolism | Immunoenzyme Techniques | Oxygen - metabolism | Antineoplastic Agents - toxicity | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Immediate-Early Proteins - metabolism | Contrast Media - pharmacology | Cisplatin - toxicity | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Kidney Tubules, Collecting - enzymology | Ischemia - pathology | Kidney Tubules, Collecting - drug effects | Kidney - drug effects | Kidney Medulla - enzymology | Kidney Tubules - drug effects | Kidney Medulla - drug effects | Mice, Inbred C57BL | RNA, Messenger - genetics | Ischemia - metabolism | Rats | Hypoxia-Inducible Factor-Proline Dioxygenases | Acute Kidney Injury - enzymology | DNA-Binding Proteins - genetics | Kidney - injuries | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Blotting, Western | Homeodomain Proteins - genetics | Animals | Immediate-Early Proteins - genetics | Podocytes - drug effects | Procollagen-Proline Dioxygenase - genetics | Kidney Tubules - enzymology | Fibroblasts - drug effects | Mice | Index Medicus | Abridged Index Medicus | Regular
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 50, Issue 1, pp. 56 - 66
Abstract Renal resident mesenchymal stem cells (MSCs) are important regulators of kidney homeostasis, repair or regeneration... 
Advanced Basic Science | Dentistry | Paracrine | Nestin | MSCs | Acute kidney injury | VEGF | PROGENITOR CELLS | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | RENAL ISCHEMIA | BONE-MARROW | ADULT | PARACRINE MECHANISMS | ACUTE TUBULAR INJURY | GROWTH-FACTOR | UP-REGULATION | EXPRESSION | MARROW STROMAL CELLS | Kidney - blood supply | Kidney - pathology | Recovery of Function - drug effects | Protective Agents - metabolism | Culture Media, Conditioned - pharmacology | Gene Expression Profiling | Vascular Endothelial Growth Factor A - metabolism | Kidney Function Tests | Kidney - metabolism | Mesenchymal Stromal Cells - cytology | Multipotent Stem Cells - drug effects | Time Factors | Ischemia - complications | Acute Kidney Injury - complications | Clone Cells | Colony-Forming Units Assay | Ischemia - pathology | Kidney - physiopathology | Fibroblasts - metabolism | Animals, Newborn | Green Fluorescent Proteins - metabolism | Mesenchymal Stromal Cells - drug effects | Acute Kidney Injury - pathology | Cell Separation | Mice, Inbred C57BL | Ischemia - therapy | Mesenchymal Stromal Cells - metabolism | Mice, Transgenic | Ischemia - physiopathology | Fibroblasts - pathology | Acute Kidney Injury - physiopathology | Nestin - metabolism | Animals | Cell Differentiation - drug effects | Multipotent Stem Cells - cytology | Fibroblasts - drug effects | Acute Kidney Injury - therapy | Cell Proliferation - drug effects | Mesenchymal Stem Cell Transplantation | Biomedical materials | Kidneys | Injury prevention | Stem cells | Markers | Repair | Injuries | Failure
Journal Article
American journal of kidney diseases, ISSN 0272-6386, 2016, Volume 67, Issue 3, pp. 431 - 438
Background Adenine phosphoribosyltransferase (APRT) deficiency is a purine metabolism disorder causing kidney stones and chronic kidney disease (CKD... 
Nephrology | End-stage renal disease | acute kidney injury (AKI) | kidney failure | purine metabolism disorder | disease progression | renal replacement therapy (RRT) | chronic kidney disease (CKD) | adenine phosphoribosyltransferase (APRT) deficiency | crystal nephropathy | kidney stone | estimated glomerular filtration rate (eGFR) | nephrolithiasis | renal function | EFFICACY | SAFETY | NEPHROPATHY | ALLOPURINOL | INFLAMMATION | RENAL-FAILURE | UROLOGY & NEPHROLOGY | EQUATION | Early Medical Intervention - methods | Iceland - epidemiology | Kidney Calculi - etiology | Prevalence | Follow-Up Studies | Humans | Renal Replacement Therapy - methods | Male | Metabolism, Inborn Errors - epidemiology | Kidney Function Tests | Adenine Phosphoribosyltransferase - metabolism | Kidney - metabolism | Early Medical Intervention - statistics & numerical data | Adenine Phosphoribosyltransferase - deficiency | Adult | Female | Renal Replacement Therapy - statistics & numerical data | Acute Kidney Injury - etiology | Kidney - physiopathology | Glomerular Filtration Rate | Kidney Failure, Chronic - diagnosis | Urolithiasis - complications | Metabolism, Inborn Errors - metabolism | Disease Progression | Kidney Calculi - diagnosis | Metabolism, Inborn Errors - diagnosis | Kidney Failure, Chronic - epidemiology | Urolithiasis - epidemiology | Urolithiasis - metabolism | Acute Kidney Injury - diagnosis | Kidney Calculi - epidemiology | Acute Kidney Injury - epidemiology | Urolithiasis - diagnosis | Kidney Calculi - prevention & control | Metabolism, Inborn Errors - complications | Kidney Failure, Chronic - etiology | end-stage kidney disease | Adenine phosphoribosyltransferase (APRT) deficiency | acute kidney injury (AKI), disease progression
Journal Article
PloS one, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, p. e0180934
Free heme, a pro-oxidant released from myoglobin, is thought to contribute to the pathogenesis of rhabdomyolysis-associated acute kidney injury (RM-AKI... 
HEMORRHAGIC-SHOCK | MESSENGER-RNA | PROTECTIVE ROLE | MULTIDISCIPLINARY SCIENCES | DELTA-AMINOLEVULINATE SYNTHASE | HEPATOMA-CELLS | NUCLEAR EXPORT | HEME OXYGENASE-1 GENE | INDUCTION | OXIDATIVE STRESS-RESPONSE | ERYTHROID-DIFFERENTIATION | Basic-Leucine Zipper Transcription Factors - metabolism | Heme - metabolism | Glycerol - adverse effects | Humans | Gene Expression Regulation | Rats | Repressor Proteins - genetics | Rhabdomyolysis - complications | Male | Acute Kidney Injury - genetics | Basic-Leucine Zipper Transcription Factors - genetics | Rhabdomyolysis - metabolism | Animals | Rhabdomyolysis - genetics | 5-Aminolevulinate Synthetase - genetics | Rhabdomyolysis - chemically induced | Cytosol - metabolism | 5-Aminolevulinate Synthetase - metabolism | Acute Kidney Injury - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Heme Oxygenase (Decyclizing) - genetics | Repressor Proteins - metabolism | Disease Models, Animal | Genetic aspects | Research | Rhabdomyolysis | Gene expression | Acute renal failure | Myoglobin | Pathogenesis | Body weight | Homology | Cytosol | Renal tubules | Computer numerical control | Nuclei | Medical schools | Antioxidants | Elevation | Rodents | Heme | Physiology | Damage | Creatinine | Limbs | Enzymes | Kidneys | Glycerol | Heme oxygenase (decyclizing) | Protein biosynthesis | Injection | Metabolism | Nitrogen | Oxygenase | Urea | Protein synthesis | Catabolism | Aspartate aminotransferase | Anesthesiology
Journal Article
Kidney international, ISSN 0085-2538, 2017, Volume 91, Issue 2, pp. 375 - 386
Journal Article
Journal Article