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Journal Article
Intensive Care Medicine, ISSN 0342-4642, 3/2010, Volume 36, Issue 3, pp. 392 - 411
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 03/2016, Volume 315, Issue 9, pp. 877 - 888
IMPORTANCE: Statins affect several mechanisms underlying acute kidney injury (AKI). OBJECTIVE: To test the hypothesis that short-term high-dose perioperative atorvastatin would reduce AKI following cardiac surgery... 
MEDICINE, GENERAL & INTERNAL | PERCUTANEOUS CORONARY INTERVENTION | ARTERY-BYPASS SURGERY | IMPROVES OUTCOMES | COA REDUCTASE INHIBITORS | PREOPERATIVE STATIN THERAPY | ACUTE DIALYSIS | RISK | ACUTE-RENAL-FAILURE | DYSFUNCTION | HEART-SURGERY | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Medication Adherence - statistics & numerical data | Glomerular Filtration Rate | Double-Blind Method | Drug Administration Schedule | Acute Kidney Injury - blood | Atorvastatin Calcium - administration & dosage | Humans | Middle Aged | Male | Cardiac Surgical Procedures - adverse effects | Renal Insufficiency, Chronic - complications | Acute Kidney Injury - prevention & control | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Aspartate Aminotransferases - blood | Aged, 80 and over | Creatinine - blood | Female | Aged | Postoperative Complications | Acute Kidney Injury - etiology | Atorvastatin Calcium - adverse effects | Prevention | Heart | Usage | Perioperative care | Kidney failure | Surgery | Clinical trials | Management | Risk factors | Kidney diseases | Drug therapy | Heart surgery | Statins | kidney | atrial fibrillation | statin | pneumonia | renal function | cardiac surgery | kidney injury | atorvastatin | CKD | delirium | AKI | surgery
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2014, Volume 63, Issue 1, pp. 62 - 70
Objectives This study sought to evaluate the safety and efficacy of rosuvastatin in preventing contrast-induced acute kidney injury (CI-AKI... 
Cardiovascular | Internal Medicine | kidney | diabetes mellitus | contrast medium | statins | angiography | C-REACTIVE PROTEIN | CARDIAC & CARDIOVASCULAR SYSTEMS | EFFICACY | CARDIOTHORACIC SURGERY | INDUCED NEPHROPATHY | RISK | ATORVASTATIN | SERUM CREATININE | PERCUTANEOUS CORONARY INTERVENTION | PRETREATMENT | STATIN THERAPY | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Renal Insufficiency, Chronic - diagnostic imaging | Male | Fluorobenzenes - administration & dosage | Renal Insufficiency, Chronic - complications | Diabetes Mellitus, Type 2 - diagnostic imaging | Dose-Response Relationship, Drug | Contrast Media - adverse effects | Time Factors | Angiography - methods | Female | Acute Kidney Injury - chemically induced | Diabetes Mellitus, Type 2 - complications | Pyrimidines - administration & dosage | Rosuvastatin Calcium | Treatment Outcome | Acute Kidney Injury - prevention & control | Angiography - adverse effects | Sulfonamides - therapeutic use | Pyrimidines - therapeutic use | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Fluorobenzenes - therapeutic use | Sulfonamides - administration & dosage | Prevention | Diabetics | Medical colleges | Care and treatment | Chronic kidney failure | Rosuvastatin | Diabetes | Diabetes therapy | Antilipemic agents | Heart failure | Oxidative stress | Heart attacks | Medical imaging | Statistical analysis | Hydration | Clinical trials | Kidney diseases | Drug therapy | Acute coronary syndromes | Cholesterol
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2009, Volume 361, Issue 1, pp. 62 - 72
.... Acute kidney injury is a dangerous complication of severe rhabdomyolysis. This review summarizes current views on the pathogenesis of myoglobin-induced kidney injury as well as on its prevention and treatment... 
Hyperkalemia - therapy | Kidney - pathology | Humans | Rhabdomyolysis - complications | Rhabdomyolysis - pathology | Rhabdomyolysis - physiopathology | Acute Kidney Injury - therapy | Acute Kidney Injury - etiology | Acute Kidney Injury - prevention & control | Kidney - physiopathology | Myoglobinuria - complications | Hyperkalemia - etiology | Prevention | Causes of | Care and treatment | Diagnosis | Rhabdomyolysis | Acute renal failure
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2019, Volume 380, Issue 22, pp. 2146 - 2155
Journal Article
Kidney international, ISSN 0085-2538, 2012, Volume 82, Issue 12, pp. 1271 - 1283
Autophagy is induced in renal tubular cells during acute kidney injury; however, whether this is protective or injurious remains controversial... 
acute kidney injury | autophagy | Atg7 | cisplatin | ischemia–reperfusion | Ischemia-reperfusion | APOPTOSIS | ACTIVATION | ACUTE-RENAL-FAILURE | PATHOLOGICAL ROLE | ischemia-reperfusion | CISPLATIN NEPHROTOXICITY | CELL-DEATH | PATHOPHYSIOLOGY | UROLOGY & NEPHROLOGY | MICE | BODY FORMATION | SELF-DIGESTION | Microtubule-Associated Proteins - genetics | Blood Urea Nitrogen | JNK Mitogen-Activated Protein Kinases - metabolism | Acute Kidney Injury - genetics | Autophagy - drug effects | Reperfusion Injury - blood | Chloroquine - pharmacology | Time Factors | Reperfusion Injury - chemically induced | Acute Kidney Injury - chemically induced | Microtubule-Associated Proteins - deficiency | Reperfusion Injury - genetics | Cytoprotection | Disease Models, Animal | Kidney Tubules, Proximal - pathology | Reperfusion Injury - pathology | Signal Transduction | Acute Kidney Injury - pathology | Acute Kidney Injury - blood | Mice, Inbred C57BL | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Biomarkers - blood | Sirolimus - pharmacology | Acute Kidney Injury - prevention & control | Cisplatin | Mice, Knockout | Autophagy-Related Protein 7 | Animals | Reperfusion Injury - prevention & control | Kidney Tubules, Proximal - metabolism | Creatinine - blood | Mice | Enzyme Activation | Apoptosis | Kidney Tubules, Proximal - drug effects
Journal Article