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1. Full Text Ketamine in Pain Therapy
by Bell, RF and Kalso, EA
SCHMERZ, ISSN 0932-433X, 04/2019, Volume 33, Issue 2, pp. 156 - 164
PERIOPERATIVE KETAMINE | SUBCUTANEOUS KETAMINE | INTRAVENOUS KETAMINE | MANAGEMENT | PATIENT-CONTROLLED ANALGESIA | MORPHINE-TOLERANCE | ACUTE POSTOPERATIVE PAIN | DOUBLE-BLIND | ANESTHESIOLOGY | LAPAROSCOPIC CHOLECYSTECTOMY | INTRATHECAL KETAMINE | CLINICAL NEUROLOGY
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2. Ketamine: A Review of Clinical Pharmacokinetics and Pharmacodynamics in Anesthesia and Pain Therapy
by Peltoniemi, Marko A and Hagelberg, Nora M and Olkkola, Klaus T and Saari, Teijo I
Clinical Pharmacokinetics, ISSN 0312-5963, 09/2016, Volume 55, Issue 9, pp. 1059 - 1077
Ketamine is a phencyclidine derivative, which functions primarily as an antagonist of the N-methyl-d-aspartate receptor. It has no affinity for... 
ORAL S-KETAMINE | PERIOPERATIVE KETAMINE | COMPARATIVE PHARMACOLOGY | POPULATION PHARMACOKINETICS | LOW-DOSE KETAMINE | SUBANESTHETIC KETAMINE | ACUTE POSTOPERATIVE PAIN | PHARMACOLOGY & PHARMACY | HEALTHY-VOLUNTEERS | CEREBRAL-BLOOD-FLOW | NORKETAMINE PLASMA-CONCENTRATIONS | Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors | Anesthesia - methods | Humans | Receptors, N-Methyl-D-Aspartate - metabolism | Cytochrome P-450 Enzyme System - metabolism | Biological Availability | Analgesics - pharmacokinetics | Cytochrome P-450 CYP2B6 - metabolism | Ketamine - administration & dosage | Dose-Response Relationship, Drug | Ketamine - adverse effects | Ketamine - analogs & derivatives | Pain - drug therapy | Analgesics - blood | Child | Analgesics - adverse effects | Ketamine - blood | Drug Administration Routes | Receptors, N-Methyl-D-Aspartate - drug effects | Pain - prevention & control | Analgesics - administration & dosage | Animals | Cytochrome P-450 CYP3A - metabolism | Ketamine - pharmacokinetics | Central Nervous System - drug effects
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3. Full Text The inflammasome as a target for pain therapy
by Zhang, H and Li, F and Li, W.-W and Stary, C and Clark, J.D and Xu, S and Xiong, X
British Journal of Anaesthesia, ISSN 0007-0912, 12/2016, Volume 117, Issue 6, pp. 693 - 707
The interleukin-1 family of cytokines are potent inducers of inflammation and pain. Proteolytic activation of this family of cytokines is under the control of... 
NOD-like receptor | caspase 1 | pain | inflammasomes | inflammation | interleukins | RHEUMATOID-ARTHRITIS | OXIDATIVE STRESS | NLRP3 INFLAMMASOME | NALP3 INFLAMMASOME | MONOSODIUM URATE CRYSTALS | NEUROPATHIC PAIN | NOD-LIKE RECEPTORS | ANESTHESIOLOGY | SPINAL-CORD-INJURY | PLACEBO-CONTROLLED TRIAL | ACUTE GOUTY-ARTHRITIS | Review
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4. Acute Pain Therapy in Appendectomy
by Freys, Stephan M
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 05/2017, Volume 52, Issue 5, p. 367
The acute pain therapy in the setting of conventional or laparoscopic appendectomy has to be initiated by the surgeon. The success of acute pain therapy holds... 
Abdominal Pain - diagnosis | Appendectomy - adverse effects | Abdominal Pain - etiology | Abdominal Pain - therapy | Humans | Treatment Outcome | Acute Pain - diagnosis | Acute Pain - etiology | Evidence-Based Medicine - standards | Acute Pain - therapy | Patient Participation - methods | Informed Consent - standards | Appendectomy - standards | Germany | Pain Management - standards | Practice Guidelines as Topic
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5. Placebo Effects in Acute Pain Therapy
by Haaga, Roland and Schnabel, Alexander
Anasthesiologie Intensivmedizin Notfallmedizin Schmerztherapie, ISSN 0939-2661, 2018, Volume 53, Issue 9, pp. 579 - 590
nocebo effect | clinical implications | placebo effect | acute pain
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6. Placebo Effects in Acute Pain Therapy
by Haaga, Roland and Schnabel, Alexander
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 09/2018, Volume 53, Issue 9, p. 579
Placebo and nocebo effects are currently within the focus of clinical and experimental pain research. Neurophysiological and psychophysiological mechanisms... 
Chronic Pain - therapy | Acute Pain - therapy | Nocebo Effect | Placebo Effect | Humans | Pain Management - methods | Hyperalgesia
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7. Full Text Postoperative pain therapy in Germany. Status quo
by Pogatzki-Zahn, EM and Meissner, W
SCHMERZ, ISSN 0932-433X, 10/2015, Volume 29, Issue 5, pp. 503 - 509
A great deal of progress has been made in the field of postoperative pain therapy in the last 20 years. Beginning from clinical trials on the effectiveness of... 
SURGERY | MANAGEMENT | METAANALYSIS | Acute pain service | Pain research | EFFICACY | Incisional pain | QUALITY IMPROVEMENT | SAFETY | Anesthesia, regional | CLINICAL NEUROLOGY | IMPACT | INTRAOPERATIVE DEXMEDETOMIDINE | Registries, acute pain | ANESTHESIOLOGY | HYPERALGESIA | CONSUMPTION | Pain, Postoperative - etiology | Analgesia, Patient-Controlled | Pain, Postoperative - therapy | Humans | Intersectoral Collaboration | Translational Medical Research | Analgesia, Epidural | Evidence-Based Medicine | Interdisciplinary Communication | Animals | Guideline Adherence | Pain, Postoperative - diagnosis | Germany | Disease Models, Animal
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8. Full Text Noninvasive treatments for acute, subacute, and chronic low back pain: A clinical practice guideline from the American College of Physicians
by Qaseem, Amir and Wilt, Timothy J and McLean, Robert M and Forciea, Mary Ann and Amer Coll Phys and Clinical Guidelines Committee of the American College of Physicians and for the Clinical Guidelines Committee of the American College of Physicians
Annals of Internal Medicine, ISSN 0003-4819, 04/2017, Volume 166, Issue 7, pp. 514 - 530
Description: The American College of Physicians (ACP) developed this guideline to present the evidence and provide clinical recommendations on noninvasive... 
RANDOMIZED-CONTROLLED-TRIAL | MEDICINE, GENERAL & INTERNAL | BUPRENORPHINE TRANSDERMAL SYSTEM | DOUBLE-BLIND | MIND-BODY PROGRAM | CONTROLLED-RELEASE OXYCODONE | PLACEBO-CONTROLLED TRIAL | LEVEL HEATWRAP THERAPY | OPIOID-NAIVE PATIENTS | QUALITY-OF-LIFE | SELF-CARE BOOK | Analgesics - therapeutic use | Chronic Pain - therapy | Hot Temperature - therapeutic use | Acute Pain - drug therapy | Chronic Pain - drug therapy | Humans | Laser Therapy | Psychotherapy | Acupuncture Therapy | Low Back Pain - therapy | Low Back Pain - drug therapy | Acute Pain - therapy | Physical Therapy Modalities | Mind-Body Therapies | Analgesics - adverse effects | Practice guidelines (Medicine) | Care and treatment | Pain | Research | Low back pain
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9. Full Text Multimodal pain therapy - Principles and indications
by Arnold, B and Brinkschmidt, T and Casser, HR and Gralow, I and Irnich, D and Klimczyk, K and Muller, G and Nagel, B and Pfingsten, M and Schiltenwolf, M and Sittl, R and Sollner, W
SCHMERZ, ISSN 0932-433X, 04/2009, Volume 23, Issue 2, pp. 112 - 112
Multimodal pain therapy describes an integrated multidisciplinary treatment in small groups with a closely coordinated therapeutical approach. Somatic and... 
Acute treatment | POPULATION | MUSCULOSKELETAL PAIN | RISK-FACTORS | LOW-BACK-PAIN | Indication | FOLLOW-UP | CHRONICITY | Chronic pain | CLINICAL NEUROLOGY | COMORBIDITY | INTERVENTIONS | Multimodal pain therapy | FIBROMYALGIA | ANESTHESIOLOGY | HEALTH | Chronification | Behavior Therapy | Recurrence | Humans | Analgesics - administration & dosage | Cooperative Behavior | Patient Care Team | Combined Modality Therapy | Pain - rehabilitation | Insurance Coverage - legislation & jurisprudence | Relaxation Therapy | National Health Programs - legislation & jurisprudence | Interdisciplinary Communication | Physical Therapy Modalities | Chronic Disease | Germany
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10. Full Text Improving postoperative pain management in children by providing regular training and an updated pain therapy concept
by Heinrich, M and Mechea, A and Hoffmann, F
European Journal of Pain, ISSN 1090-3801, 04/2016, Volume 20, Issue 4, pp. 586 - 593
Background In recent years, children's hospitals have increasingly implemented postoperative pain management protocols to reduce postoperative pain and improve... 
IMPLEMENTATION | ANESTHESIOLOGY | NONPHARMACOLOGICAL METHODS | OUTCOMES | INTERVENTION | NEUROSCIENCES | CLINICAL NEUROLOGY | Pain, Postoperative - etiology | Prospective Studies | Pain, Postoperative - therapy | Humans | Middle Aged | Pain Management | Clinical Protocols | Parents | Child, Preschool | Infant | Male | Postoperative Care - education | Acute Pain - etiology | Patient Satisfaction | Young Adult | Acute Pain - therapy | Health Personnel | Adult | Female | Surveys and Questionnaires | Child | Analgesics - therapeutic use | Acute Pain - diagnosis | Pain, Postoperative - diagnosis | Adolescent | Education, Nursing, Continuing | Pain Measurement
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11. Full Text Recent advances in postoperative pain therapy
by Power, I
British Journal of Anaesthesia, ISSN 0007-0912, 07/2005, Volume 95, Issue 1, pp. 43 - 51
analgesic techniques, i.v | therapy, non-pharmacological | enzymes, cyclooxygenase 2, inhibitors | analgesics non-opioid, nitroxyparacetamol | pain, neuropathic | pain, acute, postoperative | analgesics opioid, peripheral | analgesics non-opioid, acetaminophen | Therapy, non-pharmacological | Analgesics opioid, peripheral | Analgesics non-opioid, acetaminophen | Enzymes, cyclooxygenase 2, inhibitors | Pain, neuropathic | Analgesic techniques, i.v | Analgesics non-opioid, nitroxyparacetamol | Pain, acute, postoperative | GASTROINTESTINAL TOXICITY | NCX-701 NITROPARACETAMOL | OPIOID RECEPTOR AGONIST | INTRAVENOUS PROPACETAMOL | PERIPHERAL MORPHINE ANALGESIA | ANTINOCICEPTIVE ACTIVITY | DENTAL SURGERY | acetaminophen | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | analgesics non-opioid | ANESTHESIOLOGY | INFLAMMATORY PAIN | ASPIRIN-INDUCED ASTHMA | Acute Disease | Injections, Intravenous | Pain, Postoperative - drug therapy | Pain, Postoperative - therapy | Analgesia - methods | Humans | Acetaminophen - administration & dosage | Kidney Diseases - chemically induced | Narcotics - therapeutic use | Prostaglandin Antagonists - therapeutic use | Cyclooxygenase Inhibitors - therapeutic use | Gastrointestinal Diseases - chemically induced
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12. Full Text Recent advances in acute pain management: understanding the mechanisms of acute pain, the prescription of opioids, and the role of multimodal pain therapy [version 1; peer review: 3 approved]
by Wardhan, Richa and Chelly, Jacques
F1000Research, ISSN 2046-1402, 2017, Volume 6, p. 2065
In this review, we discuss advances in acute pain management, including the recent report of the joint American Pain Society and American Academy of Pain... 
Health Service Delivery & Management of Anesthesia | Neuropharmacology & Psychopharmacology | Pain Management: Chronic Clinical | Musculoskeletal Pain & Analgesia | Substance Abuse | Pain Management: Acute Clinical | Anesthetic Mechanisms | Pain: Basic Science | Pharmacogenetics | Multimodal therapy | Acute pain | Psychosocial factors | Pain perception | Narcotics | Physicians | Research & development--R&D | Genes | Joint surgery | Management | Addictions | Primary care | Prescription drugs | Analgesia | Analgesics | Anxieties | Pain management | Opioids | Surgeons | Anesthesia | Anesthesiology | Nonsteroidal anti-inflammatory drugs | Rehabilitation
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13. Full Text What's new in pediatric acute pain therapy?
by Schultz-Machata, Anette-Marie and Weiss, Markus and Becke, Karin
Current Opinion in Anaesthesiology, ISSN 0952-7907, 2014, Volume 27, Issue 3, pp. 316 - 322
Purpose of reviewThis review highlights the current trends of efficient and safe perioperative pediatric pain therapy in the context of a multimodal pain... 
Analgesia | pain | pediatric anesthesia | pain therapy | pediatrics | regional anesthesia | opioids | NEONATAL CIRCUMCISION | QUALITY IMPROVEMENT | FENTANYL ANESTHESIA | ABDOMINIS PLANE BLOCK | analgesia | RESPIRATORY DEPRESSION | STRESS-RESPONSE | RANDOMIZED-TRIAL | ANESTHESIOLOGY | PRETERM BABIES | POSTOPERATIVE PAIN | Pediatrics - trends | Analgesics - therapeutic use | Anesthesia, Conduction | Acute Pain - drug therapy | Pain, Postoperative - drug therapy | Pain, Postoperative - therapy | Humans | Child, Preschool | Infant | Acute Pain - therapy | Adolescent | Pain Management - trends | Pain Measurement | Child | Infant, Newborn
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14. Full Text Prevalence and Predictors of Patient Nonadherence to Pharmacological Acute Pain Therapy at Home After Day Surgery: A Prospective Cohort Study
by Stessel, Björn and Theunissen, Maurice and Marcus, Marco A and Joosten, Elbert A and van Kuijk, Sander M. J and Fiddelers, Auey A. A and Peters, Madelon L and Hoofwijk, Daisy M. N and Buhre, Wolfgang F. F. A and Gramke, Hans-Fritz
Pain Practice, ISSN 1530-7085, 02/2018, Volume 18, Issue 2, pp. 194 - 204
Background Good adherence to prescribed analgesics can be crucial to suppress or even prevent acute postoperative pain after day surgery. The aim of this study... 
postoperative | pain assessment | pain | analgesia | OXYCODONE | POSTSURGICAL PAIN | MEDICATION NONADHERENCE | ADHERENCE | CLINICAL NEUROLOGY | INDIVIDUALS | RECOVERY | CHRONIC NONMALIGNANT PAIN | AMBULATORY SURGERY | ANESTHESIOLOGY | SEVERITY | POSTOPERATIVE PAIN | Analgesics - therapeutic use | Acute Pain - drug therapy | Prevalence | Prospective Studies | Pain, Postoperative - drug therapy | Humans | Middle Aged | Pain Management - methods | Male | Patient Compliance - statistics & numerical data | Time Factors | Adult | Female | Surveys and Questionnaires | Aged | Ambulatory Surgical Procedures - adverse effects | Surgical clinics | Patient compliance | Analysis
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15. Full Text Regionally selective activation of ERK and JNK in morphine paradoxical hyperalgesia: A step toward improving opioid pain therapy
by Sanna, Maria Domenica and Ghelardini, Carla and Galeotti, Nicoletta
Neuropharmacology, ISSN 0028-3908, 11/2014, Volume 86, pp. 67 - 77
In addition to analgesia, opioid agonists may increase pain sensitivity under different conditions varying dose and administration pattern. While opioid... 
Morphine | Protein kinase C | Pain | MAPK | Hyperalgesia | PERSISTENT PAIN | DOSE MORPHINE | RATS | NEUROSCIENCES | NEUROPATHIC PAIN | SIGNAL-REGULATED KINASES | PATHWAY | ACUTE THERMAL HYPERALGESIA | NEURONS | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | HYPERSENSITIVITY |