Annals of the Academy of Medicine, Singapore, ISSN 0304-4602, 02/2018, Volume 47, Issue 2, pp. 82 - 84
MORTALITY | DEFINITION | MEDICINE, GENERAL & INTERNAL | Acute Disease | Emergency Service, Hospital | Blood Coagulation Disorders - epidemiology | Prevalence | Prognosis | Singapore | Blood Coagulation Disorders - etiology | Humans | Risk Factors | Wounds and Injuries - complications | Male | Female | Blood Coagulation Disorders - diagnosis | Retrospective Studies
Journal Article
Current Opinion in Critical Care, ISSN 1070-5295, 12/2007, Volume 13, Issue 6, pp. 680 - 685
Purpose of review Acute coagulopathy of trauma has only been described relatively recently. Developing early in the postinjury phase, it is associated with...
Shock | Massive transfusion | Protein C | Trauma | Coagulopathy | trauma | ACTIVATED PROTEIN-C | shock | ACIDOSIS | coagulopathy | PLASMINOGEN-ACTIVATOR | TRANSFUSION | MULTIPLE TRAUMA | protein C | COAGULATION ABNORMALITIES | INJURY SEVERITY | massive transfusion | SEVERE SEPSIS | FACTOR-VIIA | RESUSCITATION | CRITICAL CARE MEDICINE | Acute Disease | Blood Coagulation Disorders - etiology | Humans | Risk Factors | Wounds and Injuries - complications | Fibrinolysis | Injury Severity Score | Blood Transfusion | Blood Coagulation | Blood Coagulation Tests | Blood Coagulation Disorders - diagnosis | Shock - complications | Blood Coagulation Disorders - physiopathology
Shock | Massive transfusion | Protein C | Trauma | Coagulopathy | trauma | ACTIVATED PROTEIN-C | shock | ACIDOSIS | coagulopathy | PLASMINOGEN-ACTIVATOR | TRANSFUSION | MULTIPLE TRAUMA | protein C | COAGULATION ABNORMALITIES | INJURY SEVERITY | massive transfusion | SEVERE SEPSIS | FACTOR-VIIA | RESUSCITATION | CRITICAL CARE MEDICINE | Acute Disease | Blood Coagulation Disorders - etiology | Humans | Risk Factors | Wounds and Injuries - complications | Fibrinolysis | Injury Severity Score | Blood Transfusion | Blood Coagulation | Blood Coagulation Tests | Blood Coagulation Disorders - diagnosis | Shock - complications | Blood Coagulation Disorders - physiopathology
Journal Article
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Primary fibrinolysis is integral in the pathogenesis of the acute coagulopathy of Trauma
Annals of Surgery, ISSN 0003-4932, 2010, Volume 252, Issue 3, pp. 434 - 442
Background: The existence of primary fibrinolysis (PF) and a defined mechanistic link to the "Acute Coagulopathy of Trauma" is controversial. Rapid...
MULTIPLE INJURIES | SURGERY | LIFE-THREATENING COAGULOPATHY | ROTATION THROMBELASTOGRAPHY | PATIENT HYPOTHERMIA | CARDIAC-SURGERY | POSTINJURY COAGULOPATHY | RED-BLOOD-CELLS | CARDIOPULMONARY BYPASS | PROTEIN-C PATHWAY | FRESH-FROZEN PLASMA | Acute Disease | Prospective Studies | Thrombelastography | Blood Coagulation Disorders - etiology | Humans | Wounds and Injuries - complications | Logistic Models | Male | Blood Transfusion - statistics & numerical data | Chi-Square Distribution | Injury Severity Score | Wounds and Injuries - therapy | Point-of-Care Systems | Time Factors | Statistics, Nonparametric | Adult | Female | Blood Coagulation Disorders - diagnosis | Fibrinolysis - physiology | Blood Coagulation Disorders - physiopathology
MULTIPLE INJURIES | SURGERY | LIFE-THREATENING COAGULOPATHY | ROTATION THROMBELASTOGRAPHY | PATIENT HYPOTHERMIA | CARDIAC-SURGERY | POSTINJURY COAGULOPATHY | RED-BLOOD-CELLS | CARDIOPULMONARY BYPASS | PROTEIN-C PATHWAY | FRESH-FROZEN PLASMA | Acute Disease | Prospective Studies | Thrombelastography | Blood Coagulation Disorders - etiology | Humans | Wounds and Injuries - complications | Logistic Models | Male | Blood Transfusion - statistics & numerical data | Chi-Square Distribution | Injury Severity Score | Wounds and Injuries - therapy | Point-of-Care Systems | Time Factors | Statistics, Nonparametric | Adult | Female | Blood Coagulation Disorders - diagnosis | Fibrinolysis - physiology | Blood Coagulation Disorders - physiopathology
Journal Article
Shock, ISSN 1073-2322, 11/2012, Volume 38, Issue 5, pp. 450 - 458
Trauma remains the leading cause of death, with bleeding as the primary cause of preventable mortality. When death occurs, it happens quickly, typically within...
scoring | coagulopathy | stratification | mechanisms | Trauma | GLOBAL BURDEN | MORTALITY | SURGERY | FACTOR VIIA | MASSIVE TRANSFUSION | FRESH WHOLE-BLOOD | PERIPHERAL VASCULAR DISEASE | RED-BLOOD-CELLS | SCORING SYSTEM | HEMATOLOGY | EARLY PREDICTION | LIFE-THREATENING HEMORRHAGE | CLOT STRENGTH | CRITICAL CARE MEDICINE | Acute Disease | Humans | Disseminated Intravascular Coagulation - mortality | Wounds and Injuries - physiopathology | Wounds and Injuries - mortality | Animals | Blood Transfusion | Wounds and Injuries - therapy | Time Factors | Models, Biological | Disseminated Intravascular Coagulation - physiopathology | Hemodynamics | Disseminated Intravascular Coagulation - therapy
scoring | coagulopathy | stratification | mechanisms | Trauma | GLOBAL BURDEN | MORTALITY | SURGERY | FACTOR VIIA | MASSIVE TRANSFUSION | FRESH WHOLE-BLOOD | PERIPHERAL VASCULAR DISEASE | RED-BLOOD-CELLS | SCORING SYSTEM | HEMATOLOGY | EARLY PREDICTION | LIFE-THREATENING HEMORRHAGE | CLOT STRENGTH | CRITICAL CARE MEDICINE | Acute Disease | Humans | Disseminated Intravascular Coagulation - mortality | Wounds and Injuries - physiopathology | Wounds and Injuries - mortality | Animals | Blood Transfusion | Wounds and Injuries - therapy | Time Factors | Models, Biological | Disseminated Intravascular Coagulation - physiopathology | Hemodynamics | Disseminated Intravascular Coagulation - therapy
Journal Article
Seminars in Hematology, ISSN 0037-1963, 07/2013, Volume 50, Issue 3, pp. 259 - 269
Trauma is a leading cause of death and disability. Hemorrhage is the major mechanism responsible for death during the first 24 hours following trauma. One...
RECEIVING MASSIVE TRANSFUSIONS | DAMAGE CONTROL RESUSCITATION | ENDOTHELIAL GLYCOCALYX DEGRADATION | PROTEIN-C RECEPTOR | RECOMBINANT-FACTOR-VIIA | HYDROXYETHYL STARCH | RED-BLOOD-CELLS | HEMATOLOGY | FRESH-FROZEN PLASMA | ACTIVATED FACTOR-VII | FLUID RESUSCITATION | Acute Disease | Blood Coagulation Disorders - etiology | Humans | Wounds and Injuries - complications | Blood Coagulation Disorders - blood | Anticoagulants - therapeutic use | Blood Coagulation Disorders - physiopathology | Blood Coagulation Disorders - therapy
RECEIVING MASSIVE TRANSFUSIONS | DAMAGE CONTROL RESUSCITATION | ENDOTHELIAL GLYCOCALYX DEGRADATION | PROTEIN-C RECEPTOR | RECOMBINANT-FACTOR-VIIA | HYDROXYETHYL STARCH | RED-BLOOD-CELLS | HEMATOLOGY | FRESH-FROZEN PLASMA | ACTIVATED FACTOR-VII | FLUID RESUSCITATION | Acute Disease | Blood Coagulation Disorders - etiology | Humans | Wounds and Injuries - complications | Blood Coagulation Disorders - blood | Anticoagulants - therapeutic use | Blood Coagulation Disorders - physiopathology | Blood Coagulation Disorders - therapy
Journal Article
Critical Care, ISSN 1364-8535, 11/2014, Volume 18, Issue 6, p. 648
Introduction: Identifying patients who need damage control resuscitation (DCR) early after trauma is pivotal for adequate management of their critical...
SURVIVAL | IMPACT | PLASMA | DAMAGE CONTROL RESUSCITATION | TRANSFUSION | HEMORRHAGE | MAJOR TRAUMA | RISK | EARLY PREDICTION | EPIDEMIOLOGY | CRITICAL CARE MEDICINE | Severity of Illness Index | Acute Disease | Prospective Studies | Hemorrhage - therapy | Humans | Middle Aged | Multiple Trauma - therapy | Male | Hemorrhage - blood | Multiple Trauma - blood | Blood Coagulation Disorders - therapy | Hemorrhage - diagnosis | Multiple Trauma - diagnosis | Young Adult | Blood Coagulation | Blood Coagulation Disorders - blood | Adult | Female | Blood Coagulation Disorders - diagnosis | Emergency Medical Services - methods | Blood | Medical examination | Research
SURVIVAL | IMPACT | PLASMA | DAMAGE CONTROL RESUSCITATION | TRANSFUSION | HEMORRHAGE | MAJOR TRAUMA | RISK | EARLY PREDICTION | EPIDEMIOLOGY | CRITICAL CARE MEDICINE | Severity of Illness Index | Acute Disease | Prospective Studies | Hemorrhage - therapy | Humans | Middle Aged | Multiple Trauma - therapy | Male | Hemorrhage - blood | Multiple Trauma - blood | Blood Coagulation Disorders - therapy | Hemorrhage - diagnosis | Multiple Trauma - diagnosis | Young Adult | Blood Coagulation | Blood Coagulation Disorders - blood | Adult | Female | Blood Coagulation Disorders - diagnosis | Emergency Medical Services - methods | Blood | Medical examination | Research
Journal Article
Journal of Intensive Care, ISSN 2052-0492, 01/2017, Volume 5, Issue 1
Hemorrhage is the most important contributing factor of acute-phase mortality in trauma patients. Previously, traumatologists and investigators identified...
Trauma-induced coagulopathy | Acute traumatic coagulopathy | Disseminated intravascular coagulation | Traumatic shock | Research | Critical care | Metabolism | Trauma | Surgery | Mortality
Trauma-induced coagulopathy | Acute traumatic coagulopathy | Disseminated intravascular coagulation | Traumatic shock | Research | Critical care | Metabolism | Trauma | Surgery | Mortality
Journal Article
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, ISSN 1939-5094, 07/2018, Volume 10, Issue 4, pp. e1418 - n/a
Trauma with hypovolemic shock is an extreme pathological state that challenges the body to maintain blood pressure and oxygenation in the face of hemorrhagic...
hemorrhagic shock | platelet | thrombin | hemostasis | fibrin | PLATELET DEPOSITION | MEDICINE, RESEARCH & EXPERIMENTAL | NETWORK | BLOOD-COAGULATION | ARTERIAL TREE | SIMULATION | ACUTE CARDIOVASCULAR-RESPONSE | FLOW | THROMBIN GENERATION | MATHEMATICAL-MODEL | ISOCAPNIC HYPOXIA | Shock, Hemorrhagic - pathology | Blood Platelets - cytology | Blood Platelets - metabolism | Models, Biological | Humans | Blood Coagulation - physiology | Hemodynamics | Hemorrhage | Shock, Hemorrhagic - blood | Therapy | Transfusion | Biology | Bleeding | Blood | Clotting | Biological effects | Hemostasis | Surgery | Blood pressure | Hemostatics | Thromboembolism | Resuscitation | Computer simulation | Trauma | Thrombosis | Molecular chains | Blood circulation | Perfusion | Computation | Computer applications | Biological computing | Oxygenation
hemorrhagic shock | platelet | thrombin | hemostasis | fibrin | PLATELET DEPOSITION | MEDICINE, RESEARCH & EXPERIMENTAL | NETWORK | BLOOD-COAGULATION | ARTERIAL TREE | SIMULATION | ACUTE CARDIOVASCULAR-RESPONSE | FLOW | THROMBIN GENERATION | MATHEMATICAL-MODEL | ISOCAPNIC HYPOXIA | Shock, Hemorrhagic - pathology | Blood Platelets - cytology | Blood Platelets - metabolism | Models, Biological | Humans | Blood Coagulation - physiology | Hemodynamics | Hemorrhage | Shock, Hemorrhagic - blood | Therapy | Transfusion | Biology | Bleeding | Blood | Clotting | Biological effects | Hemostasis | Surgery | Blood pressure | Hemostatics | Thromboembolism | Resuscitation | Computer simulation | Trauma | Thrombosis | Molecular chains | Blood circulation | Perfusion | Computation | Computer applications | Biological computing | Oxygenation
Journal Article
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, ISSN 1757-7241, 10/2016, Volume 24, Issue 1, p. 114
Introduction: Viscoelastic assays have been promoted as an improvement over traditional coagulation tests in the management of trauma patients. Rotational...
Thromboelastometry | Transfusion | Bleeding | Acute trauma coagulopathy | Threshold | COAGULATION MANAGEMENT | REQUIREMENTS | HEMORRHAGE | MASSIVE TRANSFUSION | CARE | HYPERFIBRINOLYSIS | THERAPY | EMERGENCY MEDICINE | CARDIAC-SURGERY | MAJOR TRAUMA | Survival Rate - trends | Global Health | Hemostasis - physiology | Thrombelastography - methods | Wounds and Injuries - blood | Humans | Blood Coagulation Disorders - therapy | Wounds and Injuries - mortality | Wounds and Injuries - therapy | Blood Coagulation Disorders - blood | Blood Coagulation Tests | Blood Transfusion - standards | Blood Coagulation Disorders - diagnosis | Practice Guidelines as Topic | Practice guidelines (Medicine) | Physiological aspects | Evaluation | Diagnosis | Blood diseases | Wounds and injuries
Thromboelastometry | Transfusion | Bleeding | Acute trauma coagulopathy | Threshold | COAGULATION MANAGEMENT | REQUIREMENTS | HEMORRHAGE | MASSIVE TRANSFUSION | CARE | HYPERFIBRINOLYSIS | THERAPY | EMERGENCY MEDICINE | CARDIAC-SURGERY | MAJOR TRAUMA | Survival Rate - trends | Global Health | Hemostasis - physiology | Thrombelastography - methods | Wounds and Injuries - blood | Humans | Blood Coagulation Disorders - therapy | Wounds and Injuries - mortality | Wounds and Injuries - therapy | Blood Coagulation Disorders - blood | Blood Coagulation Tests | Blood Transfusion - standards | Blood Coagulation Disorders - diagnosis | Practice Guidelines as Topic | Practice guidelines (Medicine) | Physiological aspects | Evaluation | Diagnosis | Blood diseases | Wounds and injuries
Journal Article
Journal of the Royal Army Medical Corps, ISSN 0035-8665, 2009, Volume 155, Issue 4, pp. 320 - 322
Journal Article
Surgeon, The, ISSN 1479-666X, 2009, Volume 8, Issue 3, pp. 159 - 163
Abstract Recent observational studies have identified an acute coagulopathy in trauma victims that is present on arrival in the emergency room. It has been...
Surgery | Shock | Plasma | Activated Protein C | Transfusion | Trauma | Coagulopathy | MORTALITY | SURVIVAL | SURGERY | HYPOTHERMIA | PREDICTS | EXSANGUINATION PROTOCOL | MASSIVE TRANSFUSION | DAMAGE CONTROL HEMATOLOGY | BLOOD-PRODUCT UTILIZATION | INJURY SEVERITY | FRESH-FROZEN PLASMA | Acute Disease | Prognosis | Blood Coagulation Disorders - etiology | Humans | Blood Coagulation | Blood Coagulation Disorders - blood | Protein C - metabolism | Shock, Traumatic - complications
Surgery | Shock | Plasma | Activated Protein C | Transfusion | Trauma | Coagulopathy | MORTALITY | SURVIVAL | SURGERY | HYPOTHERMIA | PREDICTS | EXSANGUINATION PROTOCOL | MASSIVE TRANSFUSION | DAMAGE CONTROL HEMATOLOGY | BLOOD-PRODUCT UTILIZATION | INJURY SEVERITY | FRESH-FROZEN PLASMA | Acute Disease | Prognosis | Blood Coagulation Disorders - etiology | Humans | Blood Coagulation | Blood Coagulation Disorders - blood | Protein C - metabolism | Shock, Traumatic - complications
Journal Article
Shock, ISSN 1073-2322, 03/2015, Volume 43, Issue 3, pp. 261 - 267
Background: There are two opposing possibilities for the main pathogenesis of trauma-induced coagulopathy: an acute coagulopathy of trauma shock and...
Fibrinolytic phenotype | Thrombin | Fibrinolysis | Fibrinogenolysis | Procoagulant | SURGERY | thrombin | TIC trauma-induced coagulopathy | F factor | MARKERS | INJURY | FDP fibrinogen | MULTIPLE ORGAN DYSFUNCTION | PERIPHERAL VASCULAR DISEASE | DIC disseminated intravascular coagulation | HEMATOLOGY | TISSUE FACTOR | PROCOAGULANT ACTIVITY | CRITICAL CARE MEDICINE | fibrinolytic phenotype | fibrinogenolysis | fibrin degradation products | FgDP fibrinogen degradation products | INCREASES | ACoTS acute coagulopathy of trauma-shock | ETP endogenous thrombin potential | tPA tissue-type plasminogen activator | procoagulant | SEVERITY | Rats, Wistar | Fibrin Fibrinogen Degradation Products - metabolism | Blood Coagulation Disorders - etiology | Rats | Male | Disseminated Intravascular Coagulation - blood | Tissue Plasminogen Activator - blood | Phenotype | Animals | Thrombin - biosynthesis | Disseminated Intravascular Coagulation - etiology | Blood Coagulation Disorders - blood | Shock, Traumatic - blood | Shock, Traumatic - complications | Disease Models, Animal
Fibrinolytic phenotype | Thrombin | Fibrinolysis | Fibrinogenolysis | Procoagulant | SURGERY | thrombin | TIC trauma-induced coagulopathy | F factor | MARKERS | INJURY | FDP fibrinogen | MULTIPLE ORGAN DYSFUNCTION | PERIPHERAL VASCULAR DISEASE | DIC disseminated intravascular coagulation | HEMATOLOGY | TISSUE FACTOR | PROCOAGULANT ACTIVITY | CRITICAL CARE MEDICINE | fibrinolytic phenotype | fibrinogenolysis | fibrin degradation products | FgDP fibrinogen degradation products | INCREASES | ACoTS acute coagulopathy of trauma-shock | ETP endogenous thrombin potential | tPA tissue-type plasminogen activator | procoagulant | SEVERITY | Rats, Wistar | Fibrin Fibrinogen Degradation Products - metabolism | Blood Coagulation Disorders - etiology | Rats | Male | Disseminated Intravascular Coagulation - blood | Tissue Plasminogen Activator - blood | Phenotype | Animals | Thrombin - biosynthesis | Disseminated Intravascular Coagulation - etiology | Blood Coagulation Disorders - blood | Shock, Traumatic - blood | Shock, Traumatic - complications | Disease Models, Animal
Journal Article
Expert Review of Hematology, ISSN 1747-4086, 12/2018, Volume 11, Issue 12, pp. 987 - 995
Introduction: Despite advances in the treatment of severely injured patients that have resulted in overall improved outcomes, uncontrolled hemorrhage still...
Trauma-induced coagulopathy | damage control resuscitation (DCR) | directed coagulation therapy | coagulation management in trauma | hemostatic control in acute trauma | RECEIVING MASSIVE TRANSFUSIONS | COAGULATION COMPETENCE | SEVERELY INJURED PATIENTS | ACTIVATED FACTOR-VII | PRACTICE MANAGEMENT | TRANEXAMIC ACID | DAMAGE-CONTROL RESUSCITATION | BLOOD-TRANSFUSION | HEMATOLOGY | VASCULAR OCCLUSIVE EVENTS | THROMBOELASTOMETRY ROTEM(R)
Trauma-induced coagulopathy | damage control resuscitation (DCR) | directed coagulation therapy | coagulation management in trauma | hemostatic control in acute trauma | RECEIVING MASSIVE TRANSFUSIONS | COAGULATION COMPETENCE | SEVERELY INJURED PATIENTS | ACTIVATED FACTOR-VII | PRACTICE MANAGEMENT | TRANEXAMIC ACID | DAMAGE-CONTROL RESUSCITATION | BLOOD-TRANSFUSION | HEMATOLOGY | VASCULAR OCCLUSIVE EVENTS | THROMBOELASTOMETRY ROTEM(R)
Journal Article
Current Opinion in Pediatrics, ISSN 1040-8703, 2014, Volume 26, Issue 3, pp. 343 - 349
Purpose of reviewTo summarize our current understanding of the pathophysiology, diagnosis, and management of acute traumatic coagulopathy in children.Recent...
trauma | resuscitation | transfusion | Coagulopathy | thromboelastography | MORTALITY | RECOMBINANT FACTOR VIIA | coagulopathy | PROTEIN-C | ACTIVATED FACTOR-VII | HEMORRHAGIC-SHOCK | PLATELET DYSFUNCTION | COAGULATION TESTS | ADMISSION RAPID THROMBELASTOGRAPHY | PEDIATRICS | Acute Disease | Prospective Studies | Shock, Hemorrhagic - etiology | Thrombelastography | Humans | Risk Factors | Wounds and Injuries - complications | Child, Preschool | Shock, Hemorrhagic - therapy | Wounds and Injuries - physiopathology | Blood Coagulation Disorders - therapy | Injury Severity Score | Wounds and Injuries - therapy | Shock, Hemorrhagic - physiopathology | Blood Coagulation Tests - methods | Blood Coagulation Disorders - diagnosis | Child | Blood Coagulation Disorders - physiopathology | Resuscitation | Blood Transfusion - methods | Practice Guidelines as Topic
trauma | resuscitation | transfusion | Coagulopathy | thromboelastography | MORTALITY | RECOMBINANT FACTOR VIIA | coagulopathy | PROTEIN-C | ACTIVATED FACTOR-VII | HEMORRHAGIC-SHOCK | PLATELET DYSFUNCTION | COAGULATION TESTS | ADMISSION RAPID THROMBELASTOGRAPHY | PEDIATRICS | Acute Disease | Prospective Studies | Shock, Hemorrhagic - etiology | Thrombelastography | Humans | Risk Factors | Wounds and Injuries - complications | Child, Preschool | Shock, Hemorrhagic - therapy | Wounds and Injuries - physiopathology | Blood Coagulation Disorders - therapy | Injury Severity Score | Wounds and Injuries - therapy | Shock, Hemorrhagic - physiopathology | Blood Coagulation Tests - methods | Blood Coagulation Disorders - diagnosis | Child | Blood Coagulation Disorders - physiopathology | Resuscitation | Blood Transfusion - methods | Practice Guidelines as Topic
Journal Article
Annals of Surgery, ISSN 0003-4932, 2014, Volume 260, Issue 2, pp. 378 - 382
Objective: To determine whether prehospital nonsteroidal anti-inflammatory drug (NSAID) use may lead to a reduced incidence of trauma-induced coagulopathy...
Acute coagulopathy of trauma | Inflammation | Glue Grant | Trauma | NSAID | trauma | SCALE COLLABORATIVE PROJECT | SURGERY | PREINJURY STATIN USE | MULTIPLE-ORGAN-FAILURE | ACTIVATED PROTEIN-C | acute coagulopathy of trauma | STANDARD OPERATING PROCEDURES | CLINICAL CARE | INJURY | ORIENTED RESEARCH CORE | HOST RESPONSE | inflammation | IN-HOSPITAL SURVIVAL | Blood Coagulation Disorders - epidemiology | Risk Assessment | Comorbidity | Blood Coagulation Disorders - etiology | Humans | Middle Aged | Risk Factors | Wounds and Injuries - complications | Male | Blood Transfusion - statistics & numerical data | Trauma Severity Indices | Incidence | International Normalized Ratio | Wounds and Injuries - therapy | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Adult | Female
Acute coagulopathy of trauma | Inflammation | Glue Grant | Trauma | NSAID | trauma | SCALE COLLABORATIVE PROJECT | SURGERY | PREINJURY STATIN USE | MULTIPLE-ORGAN-FAILURE | ACTIVATED PROTEIN-C | acute coagulopathy of trauma | STANDARD OPERATING PROCEDURES | CLINICAL CARE | INJURY | ORIENTED RESEARCH CORE | HOST RESPONSE | inflammation | IN-HOSPITAL SURVIVAL | Blood Coagulation Disorders - epidemiology | Risk Assessment | Comorbidity | Blood Coagulation Disorders - etiology | Humans | Middle Aged | Risk Factors | Wounds and Injuries - complications | Male | Blood Transfusion - statistics & numerical data | Trauma Severity Indices | Incidence | International Normalized Ratio | Wounds and Injuries - therapy | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Adult | Female
Journal Article
Surgery: Official Journal of the Society of University Surgeons, Central Surgical Association, and the American Association of Endocrine Surgeons, ISSN 0039-6060, 2013, Volume 154, Issue 1, pp. 48 - 57
Background We tested the hypotheses that an increase in systemic thrombin activity occurs in both disseminated intravascular coagulation (DIC) with the...
Surgery | DEFINITION | CRITERIA | SURGERY | MULTIPLE ORGAN DYSFUNCTION | ACTIVATED PROTEIN-C | PATHWAY | SOLUBLE THROMBOMODULIN ANTIGEN | HEMOSTASIS | FAILURE | TISSUE FACTOR | SOCIETY | Acute Disease | Prospective Studies | Humans | Middle Aged | Male | Disseminated Intravascular Coagulation - blood | Thrombin - biosynthesis | Antithrombins - blood |
Surgery | DEFINITION | CRITERIA | SURGERY | MULTIPLE ORGAN DYSFUNCTION | ACTIVATED PROTEIN-C | PATHWAY | SOLUBLE THROMBOMODULIN ANTIGEN | HEMOSTASIS | FAILURE | TISSUE FACTOR | SOCIETY | Acute Disease | Prospective Studies | Humans | Middle Aged | Male | Disseminated Intravascular Coagulation - blood | Thrombin - biosynthesis | Antithrombins - blood |