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Immunity, ISSN 1074-7613, 09/2015, Volume 43, Issue 3, pp. 475 - 487
Interleukin-17 (IL-17) induces pathology in autoimmunity and infections; therefore, constraint of this pathway is an essential component of its regulation. We... 
negative regulation | Regnase-1 | fungal immunity | autoimmunity | signal transduction | IL-17 | Autoimmunity | Signal transduction | Fungal immunity | Negative regulation | EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS | IL-17 RECEPTOR | TARGET GENES | CANDIDA-ALBICANS | C/EBP-BETA | GENE-EXPRESSION | HOST-DEFENSE | NECROSIS-FACTOR-ALPHA | MESSENGER-RNA STABILITY | T-CELL | IMMUNOLOGY | Candidiasis - genetics | Oncogene Proteins - genetics | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Immunoblotting | Male | Receptors, Interleukin-17 - genetics | Ribonucleases - metabolism | Host-Pathogen Interactions - immunology | Inflammation - metabolism | Lipocalins - genetics | Adaptor Proteins, Signal Transducing - immunology | Pneumonia - immunology | Candida albicans - physiology | Encephalomyelitis, Autoimmune, Experimental - genetics | Receptors, Interleukin-17 - metabolism | Interleukin-6 - metabolism | Pneumonia - genetics | Interleukin-6 - genetics | Oncogene Proteins - metabolism | Signal Transduction - genetics | Candida albicans - immunology | Reverse Transcriptase Polymerase Chain Reaction | Mice, Knockout | Interleukin-17 - metabolism | Lipocalin-2 | Lipocalins - immunology | Interleukin-6 - immunology | Pneumonia - metabolism | Ribonucleases - genetics | Encephalomyelitis, Autoimmune, Experimental - metabolism | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | Acute-Phase Proteins - genetics | Candidiasis - microbiology | Signal Transduction - immunology | HEK293 Cells | Female | Candidiasis - immunology | Nuclear Proteins - genetics | Oncogene Proteins - immunology | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Nuclear Proteins - metabolism | Inflammation - immunology | Nuclear Proteins - immunology | Animals | Ribonucleases - immunology | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | Adaptor Proteins, Signal Transducing - metabolism | Acute-Phase Proteins - immunology | Medical colleges | Nucleases | Interleukins | RNA | Cellular signal transduction | Inflammation | Proteins | Cytokines | Rodents | Fibroblasts | Infections | Kinases | Laboratory animals | Gene expression | Experiments
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2006, Volume 281, Issue 34, pp. 24138 - 24148
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue 6, pp. 1123 - 1132
BackgroundDysbiosis has been recently demonstrated in patients with ankylosing spondylitis (AS) but its implications in the modulation of intestinal immune... 
Ankylosing Spondylitis | Infections | Inflammation | INTESTINAL INFLAMMATION | RESPONSES | CELLS | INFLAMMATORY-BOWEL-DISEASE | COLITIS | MACROPHAGES | HLA-B27 TRANSGENIC RATS | MICROBIOTA | RHEUMATOLOGY | ARTHRITIS | EXPRESSION | Human Umbilical Vein Endothelial Cells | Ileitis - blood | Up-Regulation | Cholera Toxin - blood | Intestinal Mucosa - metabolism | Junctional Adhesion Molecule A - genetics | Tight Junctions - genetics | Humans | Monocytes - immunology | Dysbiosis - microbiology | Ileum - immunology | RNA, Messenger - metabolism | Antigens, CD - genetics | Interleukin-8 | Case-Control Studies | Spondylitis, Ankylosing - immunology | Dysbiosis - immunology | Lipopolysaccharides - blood | Intestinal Mucosa - immunology | Fatty Acid-Binding Proteins - blood | Cadherins - genetics | Tight Junctions - drug effects | Adherens Junctions - genetics | Caco-2 Cells | Carrier Proteins - blood | Acute Disease | Gene Expression | Rats, Transgenic | Acute-Phase Proteins | Membrane Proteins - genetics | Membrane Glycoproteins - blood | Rats | Intestinal Mucosa - microbiology | Permeability | Carrier Proteins - genetics | Bacteria - isolation & purification | Animals | Endothelium - metabolism | Cholera Toxin - genetics | Ileitis - immunology | Anti-Bacterial Agents - pharmacology | Chronic Disease | Ileum - microbiology | HLA-B27 Antigen - genetics | Proteins | Immune response | Analysis | Research | Ankylosing spondylitis | Cells
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2013, Volume 190, Issue 9, pp. 4692 - 4706
Lipocalin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore... 
LISTERIA-MONOCYTOGENES | IMMUNE-RESPONSE | ACUTE-PHASE PROTEIN | CANDIDA-ALBICANS | LIPOCALIN 24P3 | HOST-DEFENSE | RESISTANCE | MONOCLONAL-ANTIBODY | IRON | DEFICIENT MICE | IMMUNOLOGY | NIH 3T3 Cells | Oncogene Proteins - genetics | Cytoskeletal Proteins - genetics | Cytoskeleton - immunology | Acute-Phase Proteins - genetics | Phagocytosis - genetics | Respiratory Burst - immunology | Bacterial Infections - genetics | Disease Susceptibility - immunology | Bacterial Infections - immunology | Lipocalins - genetics | Cytoskeletal Proteins - metabolism | rho GTP-Binding Proteins - immunology | Chemotaxis - immunology | Neutrophils - metabolism | Oncogene Proteins - immunology | Chemokines - immunology | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Siderophores - metabolism | rho GTP-Binding Proteins - genetics | Mice, Inbred C57BL | Cytoskeleton - genetics | Neutrophils - immunology | Oncogene Proteins - metabolism | Phagocytosis - immunology | Chemokines - genetics | Chemotaxis - genetics | Mice, Knockout | Animals | Cytoskeletal Proteins - immunology | Lipocalin-2 | Lipocalins - immunology | rho GTP-Binding Proteins - metabolism | Cytoskeleton - metabolism | Chemokines - metabolism | Mice | MicroRNAs - genetics | Respiratory Burst - genetics | Siderophores - immunology | Acute-Phase Proteins - immunology | Bacterial Infections - metabolism | Candida albicans | Listeria monocytogenes | neutrophils | Lipocalin 24p3 | Staphylococcus aureus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, p. e54600
Background and Aim: Assessment of serum concentration of lipopolysaccharide (LPS)-binding protein (LBP) has been suggested as a useful biomarker to indicate... 
INCREASED INTESTINAL PERMEABILITY | THE-159C/T POLYMORPHISM | PLASMA-LEVELS | HIGH-DENSITY | MULTIDISCIPLINARY SCIENCES | GAMMA-GLUTAMYL-TRANSFERASE | PROMOTER REGION | ALCOHOL-CONSUMPTION | POTENTIAL ROLE | BACTERIAL-ENDOTOXIN | INCREASING PROTEIN | Age Factors | Obesity - immunology | Humans | Middle Aged | Male | Acute-Phase Proteins - genetics | Obesity - blood | Obesity - genetics | Inflammation - blood | Metabolic Syndrome - blood | Adult | Female | Metabolic Syndrome - immunology | Carrier Proteins - blood | Genetic Association Studies | Membrane Glycoproteins - blood | Toll-Like Receptor 4 - genetics | Inflammation - immunology | Immunity, Innate | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Metabolic Syndrome - genetics | Adolescent | Inflammation - genetics | Lipopolysaccharide Receptors - genetics | Polymorphism, Single Nucleotide | Obesity | Blood cholesterol | Liver | Genetic aspects | Research | Mitogens | Genetic polymorphisms | Protein binding | Immunoassay | Demography | Low concentrations | Genes | Body weight | Source studies | Alcohol | Cardiovascular disease | Males | Metabolic syndrome | CD14 antigen | Lipopolysaccharides | Interleukin 6 | Proteins | Demographics | Microorganisms | Rodents | Toll-like receptors | Measurement methods | Population | Bioindicators | Lipoproteins (high density) | Interleukin 8 | Age | Immune system | Consumption | Lipopolysaccharide-binding protein | Immune response | Cytokines | Internal medicine | Abnormalities | Glycoproteins | Inflammation | TLR4 protein | Cholesterol | Serum levels | Lipoproteins | Biomarkers | Sepsis | Adults | Lifestyles | Metabolic disorders | Smoking
Journal Article
Nature Communications, ISSN 2041-1723, 01/2016, Volume 7, Issue 1, pp. 10330 - 10330
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2008, Volume 283, Issue 36, pp. 24748 - 24759
The generation of reactive oxygen species is a central feature of inflammation that results in the oxidation of host phospholipids. Oxidized phospholipids,... 
ACTIVATION | ESCHERICHIA-COLI LIPOPOLYSACCHARIDE | INDUCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | LIPID RAFTS | ENDOTHELIAL-CELLS | LOW-DENSITY-LIPOPROTEIN | HEME OXYGENASE-1 | MONOCYTE CHEMOTACTIC PROTEIN-1 | OXIDATION-PRODUCTS | T-LYMPHOCYTES | Phosphatidylcholines - immunology | Reactive Oxygen Species - metabolism | Toll-Like Receptor 2 - genetics | Membrane Glycoproteins - metabolism | Lymphocyte Antigen 96 - metabolism | Humans | Tumor Necrosis Factor-alpha - genetics | Macrophages, Peritoneal - cytology | Flagellin - pharmacology | Lymphocyte Antigen 96 - agonists | Oxidation-Reduction - drug effects | Tumor Necrosis Factor-alpha - immunology | Toll-Like Receptor 4 - agonists | p38 Mitogen-Activated Protein Kinases - metabolism | Phosphorylation - drug effects | Carrier Proteins - immunology | Guanosine - analogs & derivatives | Poly I-C - pharmacology | Macrophages, Peritoneal - immunology | Toll-Like Receptor 4 - genetics | Lipopolysaccharide Receptors - immunology | Toll-Like Receptor 4 - immunology | p38 Mitogen-Activated Protein Kinases - immunology | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 4 - metabolism | Signal Transduction - drug effects | Lipopolysaccharides - pharmacology | Toll-Like Receptor 2 - immunology | I-kappa B Kinase - immunology | Mice | Mice, Inbred BALB C | Macrophages, Peritoneal - metabolism | Oligodeoxyribonucleotides - pharmacology | Immunologic Factors - pharmacology | Lymphocyte Antigen 96 - immunology | Tumor Necrosis Factor-alpha - metabolism | Toll-Like Receptor 2 - agonists | Acute-Phase Proteins - genetics | Lipopolysaccharide Receptors - metabolism | Lymphocyte Antigen 96 - genetics | Carrier Proteins - agonists | I-kappa B Kinase - metabolism | Reactive Oxygen Species - immunology | Female | Membrane Glycoproteins - immunology | Cell Line | Acute-Phase Proteins - metabolism | Phosphatidylcholines - pharmacology | Membrane Glycoproteins - agonists | p38 Mitogen-Activated Protein Kinases - genetics | I-kappa B Kinase - genetics | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Phosphatidylcholines - genetics | Animals | Carrier Proteins - metabolism | RNA - pharmacology | Guanosine - pharmacology | Lipopolysaccharide Receptors - genetics | Signal Transduction - physiology | Acute-Phase Proteins - agonists | Acute-Phase Proteins - immunology | Lipids and Lipoproteins | Metabolism, Regulation, and Signaling
Journal Article
Journal Article
BBA - Reviews on Cancer, ISSN 0304-419X, 08/2012, Volume 1826, Issue 1, pp. 129 - 169
Neutrophil gelatinase associated lipocalin (NGAL), also known as oncogene 24p3, uterocalin, siderocalin or lipocalin 2, is a 24 kDa secreted glycoprotein... 
NGAL | Lipocalin 2 | 24p3 | Prognosis | Diagnosis | Uterocalin | ACUTE KIDNEY INJURY | URINARY BIOMARKERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION PROFILES | INITIATE LIFESAVING TREATMENT | FACTOR-KAPPA-B | ACUTE HEART-FAILURE | BIOPHYSICS | ONCOLOGY | CONTRAST-INDUCED NEPHROPATHY | GROWTH-FACTOR | RENAL REPLACEMENT THERAPY | CRITICALLY-ILL PATIENTS | Lipocalins - metabolism | Neoplasms - metabolism | Proto-Oncogene Proteins - metabolism | Oncogene Proteins - genetics | Acute-Phase Proteins - metabolism | Humans | Oncogene Proteins - metabolism | Proto-Oncogene Proteins - genetics | Acute-Phase Proteins - genetics | Inflammation - metabolism | Animals | Neoplasms - genetics | Lipocalin-2 | Lipocalins - genetics | Inflammation - genetics | Immunohistochemistry | Oxidases | Lung diseases, Obstructive | Endothelial growth factors | Leukemia | HLA histocompatibility antigens | Estrogen | Estradiol | Proteins | Liver cancer | Epidermal growth factor | Physiological aspects | Fibroblast growth factors | Vascular endothelial growth factor | Antigens | Corticosteroids | Bacterial infections | Cytochrome oxidase | Calpain | Inflammation | Crohn's disease | Transforming growth factors | Coronary heart disease | Cytochrome c | Histocompatibility antigens | Thyroid cancer | Chronic kidney failure | Analysis | Pancreatic cancer | Stem cells | Hormones, Sex | Kidney diseases | Cancer
Journal Article