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1. Full Text A Novel Role for Coenzyme A during Hydride Transfer in 3‑Hydroxy-3-methylglutaryl-coenzyme A Reductase
by Steussy, C. Nicklaus and Critchelow, Chandra J and Schmidt, Tim and Min, Jung-Ki and Wrensford, Louise V and Burgner, John W and Rodwell, Victor W and Stauffacher, Cynthia V and Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Biochemistry (Easton), ISSN 0006-2960, 08/2013, Volume 52, Issue 31, pp. 5195 - 5205
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Catalytic Domain | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Coenzyme A - chemistry | Models, Molecular | Acyl Coenzyme A - genetics | Coenzyme A - metabolism | Acyl Coenzyme A - chemistry | Pseudomonas - enzymology | Bacterial Proteins - metabolism | Catalysis | Kinetics | Acyl Coenzyme A - metabolism | Pseudomonas - chemistry | Pseudomonas - genetics | Index Medicus
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2. Full Text Crystal structure of human stearoyl-coenzyme A desaturase in complex with substrate
by Wang, Hui and Klein, Michael G and Zou, Hua and Lane, Weston and Snell, Gyorgy and Levin, Irena and Li, Ke and Sang, Bi-Ching and Argonne National Lab. (ANL), Argonne, IL (United States)
Nature structural & molecular biology, ISSN 1545-9993, 07/2015, Volume 22, Issue 7, pp. 581 - 585
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Metals - metabolism | Stearoyl-CoA Desaturase - chemistry | Humans | Models, Molecular | Stearoyl-CoA Desaturase - metabolism | Crystallography, X-Ray | Protein Conformation | Acyl Coenzyme A - metabolism | Binding Sites | Acyl Coenzyme A - chemistry | Molecular biology | Enzymes | Crystal structure | Index Medicus
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3. Full Text The 1.75 Å Crystal Structure of Acetyl-CoA Synthetase Bound to Adenosine-5‘-propylphosphate and Coenzyme A
by Gulick, Andrew M and Starai, Vincent J and Horswill, Alexander R and Homick, Kristen M and Escalante-Semerena, Jorge C
Biochemistry (Easton), ISSN 0006-2960, 03/2003, Volume 42, Issue 10, pp. 2866 - 2873
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Binding, Competitive | Acetate-CoA Ligase - isolation & purification | Amino Acid Sequence | Acetate-CoA Ligase - chemistry | Adenosine Monophosphate - chemistry | Bacterial Proteins - chemistry | Crystallization | Coenzyme A - chemistry | Coenzyme A Ligases - antagonists & inhibitors | Molecular Sequence Data | Crystallography, X-Ray | Acyl Coenzyme A - chemistry | Coenzyme A Ligases - chemistry | Enzyme Inhibitors - chemistry | Salmonella enterica - enzymology | Protein Conformation | Acetylation | Bacterial Proteins - isolation & purification | Binding Sites | Index Medicus
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4. Full Text The AibR-isovaleryl coenzyme A regulator and its DNA binding site – a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus
by Bock, Tobias and Volz, Carsten and Hering, Vanessa and Scrima, Andrea and Müller, Rolf and Blankenfeldt, Wulf
Nucleic acids research, ISSN 0305-1048, 2017, Volume 45, Issue 4, pp. 2166 - 2178
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Promoter Regions, Genetic | Transcription Factors - chemistry | Operon | Molecular Conformation | Bacterial Proteins - genetics | Myxococcus xanthus - genetics | Models, Molecular | Acyl Coenzyme A - genetics | Myxococcus xanthus - metabolism | Acyl Coenzyme A - chemistry | Transcription Factors - metabolism | Base Sequence | Bacterial Proteins - metabolism | Gene Expression Regulation, Bacterial | Acyl Coenzyme A - metabolism | Binding Sites | Index Medicus | Structural Biology
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5. Full Text LC-MS/MS-based analysis of coenzyme A and short-chain acyl-coenzyme A thioesters
by Neubauer, Stefan and Chu, Dinh Binh and Marx, Hans and Sauer, Michael and Hann, Stephan and Koellensperger, Gunda
Analytical and bioanalytical chemistry, ISSN 1618-2642, 9/2015, Volume 407, Issue 22, pp. 6681 - 6688
Biochemistry, general | Food Science | Stability | Metabolite profiling | Short-chain acyl-coenzyme A | Laboratory Medicine | LC-MS/MS | Chemistry | Analytical Chemistry | Characterization and Evaluation of Materials | Coenzyme A | Megasphaera elsdenii | Environmental Monitoring/Analysis | Biochemistry & Molecular Biology | Physical Sciences | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Science & Technology | Reproducibility of Results | Coenzyme A - analysis | Sensitivity and Specificity | Megasphaera - metabolism | Chromatography, Liquid - methods | Coenzyme A - metabolism | Tandem Mass Spectrometry - methods | Liquid chromatography | Chemical properties | Mass spectrometry | Analysis | Index Medicus | Coenzymes | Thioesters | Yeast | Mathematical analysis | Derivatives | Figure of merit | Standards
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6. Full Text Acyl-coenzyme A synthetases in metabolic control
by Ellis, Jessica M and Frahm, Jennifer L and Li, Lei O and Coleman, Rosalind A
Current opinion in lipidology, ISSN 0957-9672, 06/2010, Volume 21, Issue 3, pp. 212 - 217
β-oxidation | Acyl-CoA synthetase | Glycerolipid synthesis | Fatty acid | AMP-activated kinase | Fatty acid transport protein | Biochemistry & Molecular Biology | Endocrinology & Metabolism | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | AMP-Activated Protein Kinases - metabolism | Animals | Coenzyme A Ligases - chemistry | Biological Transport | Disease | Humans | Fatty Acids - metabolism | Coenzyme A Ligases - metabolism | Index Medicus | acyl-CoA synthetase | fatty acid | glycerolipid synthesis | fatty acid transport protein
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7. Full Text Thermophilic Coenzyme B12-Dependent Acyl Coenzyme A (CoA) Mutase from Kyrpidia tusciae DSM 2912 Preferentially Catalyzes Isomerization of (R)-3-Hydroxybutyryl-CoA and 2-Hydroxyisobutyryl-CoA
by Weichler, Maria-Teresa and Kurteva-Yaneva, Nadya and Przybylski, Denise and Schuster, Judith and Müller, Roland H and Harms, Hauke and Rohwerder, Thore
Applied and environmental microbiology, ISSN 0099-2240, 07/2015, Volume 81, Issue 14, pp. 4564 - 4572
Cobamides - metabolism | Intramolecular Transferases - genetics | Stereoisomerism | Bacillales - chemistry | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Enzyme Stability | Substrate Specificity | Acyl Coenzyme A - chemistry | Intramolecular Transferases - metabolism | Bacillales - enzymology | Bacillales - genetics | Bacillales - metabolism | Bacterial Proteins - metabolism | Catalysis | Intramolecular Transferases - chemistry | Acyl Coenzyme A - metabolism | Index Medicus | Biotechnology
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8. Full Text Coupled Ferredoxin and Crotonyl Coenzyme A (CoA) Reduction with NADH Catalyzed by the Butyryl-CoA Dehydrogenase/Etf Complex from Clostridium kluyveri
by Fuli Li and Julia Hinderberger and Henning Seedorf and Jin Zhang and Wolfgang Buckel and Rudolf K. Thauer
Journal of Bacteriology, ISSN 0021-9193, 02/2008, Volume 190, Issue 3, pp. 843 - 850
Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Metabolism. Enzymes | Bacteriology | Electron-Transferring Flavoproteins - chemistry | Oxidation-Reduction | Ferredoxins - metabolism | Electron-Transferring Flavoproteins - isolation & purification | Clostridium kluyveri - enzymology | Butyryl-CoA Dehydrogenase - chemistry | Electron-Transferring Flavoproteins - metabolism | Butyryl-CoA Dehydrogenase - metabolism | Clostridium kluyveri - growth & development | Butyryl-CoA Dehydrogenase - isolation & purification | Catalysis | Acyl Coenzyme A - metabolism | Hydrogen - metabolism | NAD - metabolism | Clostridium | Physiological aspects | Research | Enzymes | Bacteria | Chemical reactions | Biochemistry | Index Medicus | Physiology and Metabolism
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9. Full Text One-Step Transformation of Coenzyme A into Analogues by Transamidation
by Sanichar, Randy and Vederas, John C
Organic letters, ISSN 1523-7060, 04/2017, Volume 19, Issue 8, pp. 1950 - 1953
Water | Acyl Carrier Protein - chemistry | Polyketide Synthases - chemistry | Temperature | Boric Acids - chemistry | Peptide Synthases - chemistry | Cysteamine - chemistry | Coenzyme A - chemistry | Molecular Structure | Time | Catalysis | Fatty Acid Synthases - chemistry | Index Medicus
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10. Full Text Conformational flexibility of coenzyme A and its impact on the post‐translational modification of acyl carrier proteins by 4′‐phosphopantetheinyl transferases
by Nguyen, Minh Chau and Saurel, Olivier and Carivenc, Coralie and Gavalda, Sabine and Saitta, Stéphane and Tran, Mai Phuong and Milon, Alain and Chalut, Christian and Guilhot, Christophe and Mourey, Lionel and Pedelacq, Jean‐Denis
The FEBS journal, ISSN 1742-464X, 11/2020, Volume 287, Issue 21, pp. 4729 - 4746
modular PKS | PPTase | ACP | complex | protein dynamics | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Translation | Biosynthesis | pH effects | Fatty acids | Flexibility | Proteins | Domains | Natural products | Acyl carrier protein | Coenzyme A | Physiology | Protein structure | Metal ions | Structure-function relationships | Index Medicus | Life Sciences | Biomolecules | Biochemistry, Molecular Biology
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11. Full Text Directed Evolution and Structural Analysis of NADPH-Dependent Acetoacetyl Coenzyme A (Acetoacetyl-CoA) Reductase from Ralstonia eutropha Reveals Two Mutations Responsible for Enhanced Kinetics
by Ken'ichiro Matsumoto and Yoshikazu Tanaka and Tsuyoshi Watanabe and Ren Motohashi and Koji Ikeda and Kota Tobitani and Min Yao and Isao Tanaka and Seiichi Taguchi
Applied and Environmental Microbiology, ISSN 0099-2240, 10/2013, Volume 79, Issue 19, pp. 6134 - 6139
Life Sciences & Biomedicine | Microbiology | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biotechnology | Protein engineering | Biological and medical sciences | Methods. Procedures. Technologies | Gene Expression | Corynebacterium glutamicum - genetics | Models, Molecular | Alcohol Oxidoreductases - metabolism | Crystallography, X-Ray | Directed Molecular Evolution | Mutation, Missense | NADP - chemistry | Acyl Coenzyme A - chemistry | Alcohol Oxidoreductases - genetics | Coenzymes - metabolism | Corynebacterium glutamicum - metabolism | Polyesters - metabolism | Alcohol Oxidoreductases - chemistry | DNA Mutational Analysis | Escherichia coli - genetics | Escherichia coli - metabolism | Polymerase Chain Reaction | Protein Conformation | Cupriavidus necator - enzymology | Kinetics | NADP - metabolism | Hydroxybutyrates - metabolism | Acyl Coenzyme A - metabolism | Gene mutations | Physiological aspects | Coenzyme A | Evolution | Influence | Genetic aspects | Research | Gram-negative bacteria | Structure | Polymerase chain reaction | Enzymes | Mutagenesis | E coli | Mutation | Crystal structure | Index Medicus | Enzymology and Protein Engineering
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12. Full Text Stable isotope dilution liquid chromatography/mass spectrometry analysis of cellular and tissue medium‐ and long‐chain acyl‐coenzyme A thioesters
by Snyder, Nathaniel W and Basu, Sankha S and Zhou, Zinan and Worth, Andrew J and Blair, Ian A
Rapid communications in mass spectrometry, ISSN 0951-4198, 08/2014, Volume 28, Issue 16, pp. 1840 - 1848
Cell Line | Fatty Acids - chemistry | Humans | Mice, Inbred C57BL | Pantothenic Acid - chemistry | Fatty Acids - analysis | Liver - chemistry | Acyl Coenzyme A - chemistry | Isotope Labeling - methods | Animals | Acyl Coenzyme A - analysis | Esters - chemistry | Cell Line, Tumor | Mice | Chromatography, Liquid - methods | Mass Spectrometry - methods | Enzymes | Colon cancer | Thiols | Analysis | Physiological aspects | Liquid chromatography | Chemical synthesis | Fatty acids | Mass spectrometry | Index Medicus | Biotechnology | Dilution | Thioesters | Colon | Isotopes | Standards
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