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Journal Article
Nature Communications, ISSN 2041-1723, 05/2016, Volume 7, Issue 1, pp. 11671 - 11671
Less than half of patients suffering from major depressive disorder, a leading cause of disability worldwide, achieve remission with current antidepressants,... 
DOPAMINE NEURONS | PATHWAY | SOCIAL DEFEAT | PHARMACOLOGY | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | NEUROBIOLOGY | STRESS | RETIGABINE | KV7 K+ CHANNELS | Adaptation, Psychological - physiology | Phenylenediamines - therapeutic use | Depressive Disorder, Major - metabolism | Humans | Male | Resilience, Psychological - drug effects | Ventral Tegmental Area - cytology | Ventral Tegmental Area - physiology | Stress, Psychological - psychology | Dopaminergic Neurons - metabolism | Membrane Transport Modulators - pharmacology | Stress, Psychological - metabolism | Dopaminergic Neurons - drug effects | Behavior, Animal - drug effects | Antidepressive Agents - pharmacology | Carbamates - pharmacology | Depressive Disorder, Major - drug therapy | Disease Models, Animal | Depressive Disorder, Major - physiopathology | Ventral Tegmental Area - drug effects | KCNQ3 Potassium Channel - metabolism | Stress, Psychological - drug therapy | Adaptation, Psychological - drug effects | Mice, Inbred C57BL | Behavior, Animal - physiology | Antidepressive Agents - therapeutic use | Depressive Disorder, Major - psychology | Animals | Ventral Tegmental Area - metabolism | Membrane Transport Modulators - therapeutic use | Phenylenediamines - pharmacology | Mice | Electrophysiological Phenomena | Carbamates - therapeutic use | Potentiation | Ventral tegmentum | Signs and symptoms | Dopamine | Target recognition | Hyperactivity | Potassium channels | Mental depression | Channels | Resilience | Infusion | Social interactions | Antidepressants | Remission | Potassium channels (voltage-gated) | Potassium | Dopamine receptors | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 2010, Volume 67, Issue 4, pp. 656 - 666
The central nucleus of the amygdala (CeA) serves as a major output of this structure and plays a critical role in the expression of conditioned fear. By... 
PHARMACOLOGICAL MRI | EXTENDED AMYGDALA | RAT | CENTRAL NUCLEUS | FUNCTIONAL CONNECTIVITY | VASOPRESSIN | OXYTOCIN | BINDING-SITES | AMYGDALOID COMPLEX | NEUROSCIENCES | BRAIN | Adaptation, Psychological - physiology | Serotonin 5-HT1 Receptor Agonists | Amygdala - drug effects | Neural Pathways - drug effects | Blood Volume - drug effects | Fear - drug effects | Male | Fear - physiology | Brain - physiology | Freezing Reaction, Cataleptic - drug effects | Neural Pathways - physiology | Oxytocin - metabolism | Brain - blood supply | Neurons - physiology | Mice, Inbred CBA | Amygdala - blood supply | Neurons - drug effects | Action Potentials - drug effects | Receptor, Serotonin, 5-HT1A - metabolism | Neural Pathways - blood supply | Conditioning, Classical - drug effects | Cerebrovascular Circulation - drug effects | Adaptation, Psychological - drug effects | Mice, Inbred C57BL | Mice, Transgenic | Conditioning, Classical - physiology | Action Potentials - physiology | Brain - drug effects | Magnetic Resonance Imaging | Animals | Freezing Reaction, Cataleptic - physiology | Mice | Models, Neurological | In Vitro Techniques | Amygdala - physiology | Serotonin 5-HT1 Receptor Antagonists | Neurons | Neurosciences | Parasympatholytic agents | Studies | Brain | Correlation analysis | Transgenic animals | Rodents | Behavior | Experiments | Index Medicus | Amygdala
Journal Article
Neuroscience, ISSN 0306-4522, 2010, Volume 167, Issue 3, pp. 741 - 749
Abstract The estrogen-mimicking endocrine disrupter bisphenol A (BPA) which is used in the manufacture of plastic and epoxy resins, is one of the world's most... 
Neurology | glucocorticoid receptors | hippocampus | endocrine disrupters | Y-maze | Endocrine disrupters | Glucocorticoid receptors | Hippocampus | BEHAVIOR | RECEPTOR EXPRESSION | CHRONIC STRESS | NEUROSCIENCES | HORMONE RECEPTORS | FEMALE RATS | GENE-EXPRESSION | SPATIAL MEMORY | SEX-DIFFERENCES | PITUITARY-ADRENAL AXIS | Adaptation, Psychological - physiology | Memory Disorders - physiopathology | Receptors, Steroid - metabolism | Rats, Wistar | Phenols - toxicity | Memory Disorders - metabolism | Male | Hippocampus - drug effects | Brain - metabolism | Dose-Response Relationship, Drug | Exploratory Behavior - physiology | Exploratory Behavior - drug effects | Neurosecretory Systems - metabolism | Female | Anxiety - metabolism | Hypothalamo-Hypophyseal System - physiopathology | Neurosecretory Systems - physiopathology | Hypothalamo-Hypophyseal System - drug effects | Pituitary-Adrenal System - physiopathology | Benzhydryl Compounds | Maze Learning - physiology | Pituitary-Adrenal System - drug effects | Adaptation, Psychological - drug effects | Brain - physiopathology | Anxiety - physiopathology | Rats | Receptors, Steroid - drug effects | Prenatal Exposure Delayed Effects - physiopathology | Sex Characteristics | Maze Learning - drug effects | Prenatal Exposure Delayed Effects - metabolism | Endocrine Disruptors - toxicity | Brain - drug effects | Environmental Exposure - adverse effects | Pregnancy | Hippocampus - metabolism | Animals | Estrogens, Non-Steroidal - toxicity | Neurosecretory Systems - drug effects | Anxiety - chemically induced | Corticosterone - metabolism | Corticosterone - agonists | Hippocampus - physiopathology | Prenatal Exposure Delayed Effects - chemically induced | Memory Disorders - chemically induced | Index Medicus
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 09/2013, Volume 38, Issue 10, pp. 2057 - 2067
Coping is defined as the behavioral and physiological effort made to master stressful situations. The ability to cope with stress leads either to healthy or to... 
disconnection | GABA | serotonin | corticolimbic | coping | SEROTONIN TRANSPORTER | RAT BASOLATERAL AMYGDALA | PSYCHIATRY | FOS EXPRESSION | MAJOR DEPRESSION | CONDITIONED FEAR | SYNAPTIC PLASTICITY | NEUROSCIENCES | RESTRAINT STRESS | CORTICOTROPIN-RELEASING-FACTOR | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | DORSAL RAPHE NUCLEUS | Adaptation, Psychological - physiology | Immobility Response, Tonic - physiology | Amygdala - drug effects | Neural Pathways - drug effects | gamma-Aminobutyric Acid - metabolism | Male | Stress, Psychological - psychology | Allylglycine - pharmacology | Neural Pathways - physiology | Allylglycine - administration & dosage | Brain - metabolism | Prefrontal Cortex - drug effects | 5,7-Dihydroxytryptamine - administration & dosage | Stress, Psychological - metabolism | Immobility Response, Tonic - drug effects | Dopamine - metabolism | Microinjections | Adaptation, Psychological - drug effects | Amygdala - metabolism | 5,7-Dihydroxytryptamine - pharmacology | GABA Antagonists - pharmacology | Brain - drug effects | Animals | Norepinephrine - metabolism | Serotonin - metabolism | Prefrontal Cortex - metabolism | Neural Pathways - metabolism | Mice | Amygdala - physiology | Prefrontal Cortex - physiology | Stress, Psychological - physiopathology | Index Medicus | anxiety | behavioral science | mood | stress disorders | Original
Journal Article
Psychopharmacology, ISSN 0033-3158, 9/2015, Volume 232, Issue 17, pp. 3123 - 3133
Journal Article
Molecular Psychiatry, ISSN 1359-4184, 11/2008, Volume 13, Issue 11, pp. 1028 - 1042
Hypersecretion of central corticotropin-releasing hormone (CRH) has been implicated in the pathophysiology of affective disorders. Both, basic and clinical... 
Depression | ROSA26 | HPA axis | Forced swim test | Corticotropin-releasing hormone | DMP696 | NERVOUS-SYSTEM | corticotropin-releasing hormone | PSYCHIATRY | BIOCHEMISTRY & MOLECULAR BIOLOGY | FORCED SWIMMING TEST | ANXIETY-LIKE BEHAVIOR | NEUROSCIENCES | MICE LACKING | REDUCED ANXIETY | MESSENGER-RNAS | PARAVENTRICULAR NUCLEUS | CRF1 RECEPTOR ANTAGONIST | LOCUS-COERULEUS | depression | forced swim test | Adaptation, Psychological - physiology | Brain Chemistry - drug effects | Nestin | Central Nervous System - metabolism | Receptors, Corticotropin-Releasing Hormone - metabolism | Fenclonine - administration & dosage | Fenclonine - analogs & derivatives | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Methyltyrosines - administration & dosage | Central Nervous System - anatomy & histology | Mice, Mutant Strains | Intermediate Filament Proteins - genetics | Corticotropin-Releasing Hormone - antagonists & inhibitors | Female | Corticotropin-Releasing Hormone - genetics | Swimming | Pyrazoles - pharmacology | Exploratory Behavior | Hypothalamo-Hypophyseal System - drug effects | Triazines - pharmacology | Pituitary-Adrenal System - drug effects | Pituitary-Adrenal System - metabolism | Stress, Physiological - genetics | Stress, Psychological - drug therapy | Adaptation, Psychological - drug effects | Mice, Inbred C57BL | RNA, Untranslated | Mice, Transgenic | Hindlimb Suspension | Nerve Tissue Proteins - genetics | Corticotropin-Releasing Hormone - metabolism | Hypothalamo-Hypophyseal System - metabolism | Proteins - genetics | Stress, Psychological - genetics | Animals | Analysis of Variance | Central Nervous System - drug effects | Mice | Radioimmunoassay - methods | Stress, Psychological - etiology | Corticotropin releasing hormone | Psychological aspects | Care and treatment | Genetic aspects | Research | Depression, Mental | Index Medicus
Journal Article
Journal of Psychiatric Research, ISSN 0022-3956, 2014, Volume 53, Issue 1, pp. 1 - 7
Abstract Stressful life events during childhood and adolescence are important risk factors for the development of psychopathologies later in life. The... 
Psychiatry | Corticotropin releasing hormone | Anxiety-like behavior | Stress-coping behavior | Social behavior | NBI30775 | Peripuberty stress | DEPRESSION | ANTAGONIST R121919 | PSYCHIATRY | BASOLATERAL AMYGDALA | HPA AXIS GENES | HORMONE-RECEPTOR 1 | CHILDHOOD TRAUMA | CORTICOTROPIN-RELEASING-FACTOR | ANXIETY-RELATED BEHAVIOR | FACTOR SYSTEMS | NEURAL CIRCUITS | Adaptation, Psychological - physiology | Amygdala - drug effects | Receptors, Corticotropin-Releasing Hormone - metabolism | Age Factors | Rats, Wistar | Receptors, Corticotropin-Releasing Hormone - genetics | Male | Hippocampus - drug effects | Social Behavior Disorders - drug therapy | Swimming - psychology | Disease Models, Animal | Gene Expression Regulation, Developmental - physiology | Animals, Newborn | Maze Learning - physiology | Stress, Psychological - drug therapy | Adaptation, Psychological - drug effects | Amygdala - metabolism | Gene Expression Regulation, Developmental - drug effects | Rats | Pyrimidines - pharmacology | Maze Learning - drug effects | Hormone Antagonists - pharmacology | Stress, Psychological - pathology | Hippocampus - metabolism | Stress, Psychological - genetics | Animals | Pyrimidines - therapeutic use | Social Behavior Disorders - etiology | Hormone Antagonists - therapeutic use | In Vitro Techniques | Stress, Psychological - complications | Puberty | Adolescence | Behavior genetics | Animal behavior | Neurohormones | Stress management | ACTH | Stress (Psychology) | Risk factors | Index Medicus
Journal Article