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Methods, ISSN 1046-2023, 02/2017, Volume 115, pp. 80 - 90
We present TrackMate, an open source Fiji plugin for the automated, semi-automated, and manual tracking of single-particles. It offers a versatile and modular... 
Phototoxicity | Open-source software | Image analysis | Single-particle tracking | Microscopy | Clathin-mediated endocytosis | SYSTEM | CLATHRIN-MEDIATED ENDOCYTOSIS | TPLATE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | TRANSPORT | DYNAMICS | ARABIDOPSIS | CELL | EMBRYOGENESIS | Image Processing, Computer-Assisted - statistics & numerical data | Plant Cells - metabolism | Adaptor Proteins, Vesicular Transport - genetics | Cell Tracking - methods | Embryo, Nonmammalian - metabolism | Arabidopsis - ultrastructure | Clathrin - genetics | Adaptor Proteins, Vesicular Transport - metabolism | Fibroblasts - ultrastructure | Cell Tracking - statistics & numerical data | Clathrin - metabolism | Arabidopsis - metabolism | Caenorhabditis elegans | Endocytosis | Algorithms | Animals | Light Signal Transduction | Single-Cell Analysis - statistics & numerical data | Single-Cell Analysis - methods | Embryo, Nonmammalian - ultrastructure | Plant Cells - ultrastructure | Gene Expression Regulation, Plant | Software | Fibroblasts - metabolism | Index Medicus | Single-Cell Analysis/methods | Arabidopsis/metabolism | Embryo, Nonmammalian/ultrastructure | Cellular Biology | Life Sciences | Clathrin/genetics | Fibroblasts/metabolism | Cell Tracking/methods | Plant Cells/metabolism | Cell Tracking/statistics & numerical data | Arabidopsis/ultrastructure | Image Processing, Computer-Assisted/statistics & numerical data | Embryo, Nonmammalian/metabolism | Adaptor Proteins, Vesicular Transport/genetics | Clathrin/metabolism | Plant Cells/ultrastructure | Single-Cell Analysis/statistics & numerical data | Fibroblasts/ultrastructure | Adaptor Proteins, Vesicular Transport/metabolism
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 2009, Volume 35, Issue 5, pp. 563 - 573
The target of rapamycin complex 1 (TORC1) is a central regulator of eukaryotic cell growth that is activated by a variety of hormones (e.g., insulin) and... 
CELLBIO | PROTEINS | SIGNALING | YEAST SACCHAROMYCES-CEREVISIAE | CELL-GROWTH CONTROL | SIGNALING PATHWAYS | FUNCTIONAL HOMOLOG | RAG GTPASES | VACUOLE FUSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMINO-ACID PERMEASE | COMPONENT | GTP-BINDING PROTEINS | GAP1 PERMEASE | CELL BIOLOGY | Vacuoles - enzymology | Intracellular Membranes - enzymology | Saccharomyces cerevisiae - genetics | Multiprotein Complexes | Adaptor Proteins, Vesicular Transport - genetics | Saccharomyces cerevisiae - drug effects | Guanosine Triphosphate - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Vacuoles - drug effects | DNA-Binding Proteins - metabolism | Amino Acids - metabolism | Time Factors | Guanine Nucleotide Exchange Factors - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Guanosine Diphosphate - metabolism | Protein Synthesis Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Saccharomyces cerevisiae Proteins - antagonists & inhibitors | Monomeric GTP-Binding Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Amino Acid Transport Systems - metabolism | Sirolimus - pharmacology | Cycloheximide - pharmacology | Protein Transport | Transcription Factors - metabolism | Monomeric GTP-Binding Proteins - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Saccharomyces cerevisiae - enzymology | Endosomes - enzymology | Intracellular Membranes - drug effects | Mutation | Saccharomyces cerevisiae - growth & development | Proteins | Purines | Amino acids | Gross domestic product | Guanosine | Index Medicus
Journal Article
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2010, Volume 466, Issue 7307, pp. 714 - 719
Recent genome-wide association studies (GWASs) have identified a locus on chromosome 1p13 strongly associated with both plasma low-density lipoprotein... 
POPULATION | DENSITY-LIPOPROTEIN CHOLESTEROL | TRANSPORT | DESIGN | PROTEIN | GENE | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | SORTILIN | CORONARY-ARTERY-DISEASE | GENOME-WIDE ASSOCIATION | Myocardial Infarction - blood | Myocardial Infarction - genetics | Adaptor Proteins, Vesicular Transport - biosynthesis | Humans | Adaptor Proteins, Vesicular Transport - deficiency | Adaptor Proteins, Vesicular Transport - genetics | Hepatocytes - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Coronary Artery Disease - blood | Europe - ethnology | Gene Knockdown Techniques | Haplotypes - genetics | Base Sequence | Lipids - blood | Cholesterol, LDL - blood | Transcription, Genetic | Chromosomes, Human, Pair 1 - genetics | Binding Sites | CCAAT-Enhancer-Binding Proteins - metabolism | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Liver - metabolism | Cells, Cultured | Gene Expression Regulation | Phenotype | Animals | Lipoproteins, VLDL - blood | Lipoproteins, VLDL - metabolism | Coronary Artery Disease - genetics | Cholesterol, LDL - metabolism | Polymorphism, Single Nucleotide - genetics | Liver - cytology | Mice | Cohort Studies | Genetic aspects | Genetic variation | Health aspects | Heart attack | Cholesterol | Proteins | Haplotypes | Studies | Plasma | Lipoproteins | Genetics | Cardiovascular disease | Artificial chromosomes | Gene expression | Statins | Index Medicus
Journal Article
Molecular Biology of the Cell, ISSN 1059-1524, 12/2008, Volume 19, Issue 12, pp. 5360 - 5372
Class III phosphatidylinositol 3-kinase (PI3-kinase) regulates multiple membrane trafficking. In yeast, two distinct PI3-kinase complexes are known: complex I... 
PRE-AUTOPHAGOSOMAL STRUCTURE | LATE ENDOSOMES | MOLECULAR MACHINERY | PROTEIN-KINASE | TRANS-GOLGI NETWORK | TUMOR-SUPPRESSOR | VPS34 PTDINS 3-KINASE | SACCHAROMYCES-CEREVISIAE | SELECTIVE AUTOPHAGY | SELF-DIGESTION | CELL BIOLOGY | Autophagy-Related Proteins | Adaptor Proteins, Vesicular Transport - classification | Humans | Adaptor Proteins, Vesicular Transport - genetics | Molecular Sequence Data | rab GTP-Binding Proteins - genetics | Autophagy - physiology | Phosphatidylinositol 3-Kinases - metabolism | Phylogeny | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Adaptor Proteins, Vesicular Transport - metabolism | Recombinant Fusion Proteins - metabolism | Multiprotein Complexes - metabolism | RNA Interference | Tumor Suppressor Proteins - genetics | Apoptosis Regulatory Proteins - genetics | Phagosomes - ultrastructure | Cell Membrane - metabolism | Membrane Proteins - metabolism | Androstadienes - metabolism | Beclin-1 | rab GTP-Binding Proteins - metabolism | Amino Acid Sequence | Cell Line | Tumor Suppressor Proteins - metabolism | Membrane Proteins - genetics | Phagosomes - metabolism | Apoptosis Regulatory Proteins - metabolism | Endocytosis - physiology | Phosphatidylinositol 3-Kinases - genetics | Multiprotein Complexes - chemistry | Sequence Alignment | Animals | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Mice | Index Medicus
Journal Article
Science, ISSN 0036-8075, 03/2015, Volume 347, Issue 6227, pp. 1217 - U17
Journal Article
Autophagy, ISSN 1554-8627, 03/2016, Volume 12, Issue 3, pp. 547 - 564
Journal Article
Neuron, ISSN 0896-6273, 02/2013, Volume 77, Issue 3, pp. 485 - 502
Journal Article
Science, ISSN 0036-8075, 11/2012, Volume 338, Issue 6108, pp. 810 - 814
Fluorescent proteins (FPs) are widely used as optical sensors, whereas other light-absorbing domains have been used for optical control of protein localization...