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Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 329, Issue 5996, pp. 1168 - 1174
The Centre for the AIDS Program of Research in South Africa (CAPRISA) 004 trial assessed the effectiveness and safety of a 1% vaginal gel formulation of... 
Human sexual behavior | HIV infections | Antiinfectives | Gels | HIV | RESEARCH ARTICLES | Placebos | Experimentation | AIDS | Infections | Condoms | VAGINAL GEL | INDIVIDUALS | SOUTH-AFRICA | PROPHYLAXIS | IN-VITRO | TRANSMISSION | MULTIDISCIPLINARY SCIENCES | CLINICAL-TRIALS | MALE CIRCUMCISION | RANDOMIZED CONTROLLED-TRIAL | CHALLENGES | HIV Infections - prevention & control | Anti-Infective Agents, Local - therapeutic use | Urban Population - statistics & numerical data | HIV Infections - epidemiology | Humans | Anti-Infective Agents, Local - adverse effects | Drug Resistance, Viral | Administration, Intravaginal | Viral Load | Incidence | Anti-HIV Agents - administration & dosage | Tenofovir | Young Adult | Adenine - adverse effects | HIV-1 - physiology | Adenine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Vaginal Creams, Foams, and Jellies | Rural Population - statistics & numerical data | Sexual Behavior | Adenine - analogs & derivatives | Double-Blind Method | Organophosphonates - therapeutic use | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | South Africa - epidemiology | Organophosphonates - adverse effects | Adenine - administration & dosage | Pregnancy | Organophosphonates - administration & dosage | Anti-Infective Agents, Local - administration & dosage | Adolescent | Patient Compliance | Pregnancy Outcome | Prevention | Anti-infective agents | Research | HIV infection
Journal Article
Annals of neurology, ISSN 1531-8249, 2009, Volume 66, Issue 3, pp. 378 - 389
Journal Article
Journal of acquired immune deficiency syndromes (1999), ISSN 1525-4135, 2013, Volume 63, Issue 4, pp. 449 - 455
Journal Article
Pediatric nephrology (Berlin, West), ISSN 1432-198X, 2018, Volume 34, Issue 3, pp. 435 - 442
Adenine phosphoribosyltransferase (APRT) deficiency is a hereditary purine metabolism disorder that causes kidney stones and chronic kidney disease (CKD). The... 
Pediatrics | Nephrology | Kidney failure | Medicine & Public Health | Allopurinol | Chronic kidney disease | Nephrolithiasis | Children | Urology | Kidney stones | Crystal nephropathy | Kidney transplantation | KIDNEY-DISEASE | ADENINE PHOSPHORIBOSYLTRANSFERASE DEFICIENCY | URINARY 2,8-DIHYDROXYADENINE | UROLOGY & NEPHROLOGY | PEDIATRICS | EQUATION | Xanthine Dehydrogenase - metabolism | Kidney Calculi - etiology | Recurrence | Follow-Up Studies | Renal Insufficiency, Chronic - etiology | Xanthine Dehydrogenase - antagonists & inhibitors | Humans | Child, Preschool | Infant | Male | Adenine - chemistry | Glomerular Filtration Rate - physiology | Renal Insufficiency, Chronic - epidemiology | Young Adult | Adenine Phosphoribosyltransferase - metabolism | Registries - statistics & numerical data | Adenine Phosphoribosyltransferase - deficiency | Adult | Female | Kidney Calculi - chemistry | Child | Acute Kidney Injury - etiology | Kidney - physiopathology | Adenine - analogs & derivatives | Adenine Phosphoribosyltransferase - genetics | Urolithiasis - drug therapy | Urolithiasis - complications | Metabolism, Inborn Errors - metabolism | Acute Kidney Injury - physiopathology | Metabolism, Inborn Errors - genetics | Renal Insufficiency, Chronic - physiopathology | Disease Progression | Allopurinol - therapeutic use | Kidney Calculi - diagnosis | Urolithiasis - metabolism | Adolescent | Kidney Calculi - epidemiology | Adenine - metabolism | Acute Kidney Injury - epidemiology | Metabolism, Inborn Errors - drug therapy | Urolithiasis - genetics | Metabolism, Inborn Errors - complications | Complications and side effects | Prognosis | Chronic kidney failure | Adenine | Physiological aspects | Metabolic diseases | Research | Risk factors | Kidneys | Epidermal growth factor receptors | Patients | Glomerular filtration rate | Calculi | Lithiasis | Phosphoribosyltransferase | Kidney diseases | Adenine phosphoribosyltransferase | Drug therapy | Age
Journal Article
Protein science, ISSN 0961-8368, 2009, Volume 11, Issue 9, pp. 2125 - 2137
A computational comparison of 102 high‐resolution (≤1.90 Å) enzyme‐dinucleotide (NAD, NADP, FAD) complexes was performed to investigate the role of solvent in... 
NAD, nicotinamide adenine dinucleotide | RMSD, root‐mean‐square deviation | Rn, nicotinamide ribose | CNS, crystallography and NMR system | A, adenine | NMN, nicotinamide adenine mononucleotide | NADP, nicotinamide adenine dinucleotide phosphate | GDP, Guanosine diphosphate | NADP | dTDP, deoxythymidine diphosphate | structurally conserved water molecule | ADH, alcohol dehydrogenase | GAPDH, d‐glyceraldehyde‐3‐phosphate dehydrogenase | FAD, flavin adenine dinucleotide | P, pyrophosphate | PDB, Protein Data Bank | UDP‐galactose, uridine 5′‐diphosphate galactose | FAD | Ra, adenine ribose | N, nicotinamide | CoA, coenzyme A | NAD | dh, dehydrogenase | rd, reductase | Rossmann fold | molecular recognition | ACP, acyl carrier protein | dinucleotide‐protein interactions | EBI‐MSD, European Bioinformatics Institute Macromolecular Structure Database | Structurally conserved water molecule | Dinucleotide-protein interactions | Molecular recognition | 1.9 ANGSTROM RESOLUTION | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-RAY STRUCTURE | UDP-GALACTOSE 4-EPIMERASE | NICOTINAMIDE ADENINE-DINUCLEOTIDE | CARRIER PROTEIN REDUCTASE | dinucleotide-protein interactions | TRYPANOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE | LIVER ALCOHOL-DEHYDROGENASE | ALBICANS DIHYDROFOLATE-REDUCTASE | AMINO-ACID-RESIDUES | REFINED CRYSTAL-STRUCTURE | Flavin-Adenine Dinucleotide - chemistry | Fungal Proteins - chemistry | Solvents - chemistry | Humans | Bacterial Proteins - chemistry | Models, Molecular | NADP - chemistry | Protein Folding | NAD - chemistry | Animals | Glycine - chemistry | Hydrogen Bonding | Plant Proteins - chemistry | Water - chemistry | Protein Binding | Protein Conformation | Protozoan Proteins - chemistry | Molecular Structure | Binding Sites
Journal Article