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1. Full Text Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3, non-inferiority trial
by DeJesus, Edwin and Rockstroh, Jürgen K, MD and Henry, Keith, MD and Molina, Jean-Michel, MD and Gathe, Joseph, MD and Ramanathan, Srinivasan, PhD and Wei, Xuelian, PhD and Yale, Kitty, MSc and Szwarcberg, Javier, MD and White, Kirsten, Prof and Cheng, Andrew K, MD and Kearney, Brian P, Prof and GS-236-0103 Study Team
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 379, Issue 9835, pp. 2429 - 2438
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antiviral agents | General aspects | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Antibiotics. Antiinfectious agents. Antiparasitic agents | HIV-1 | Humans | Middle Aged | Male | Thiazoles - administration & dosage | Carbamates - administration & dosage | Anti-HIV Agents - administration & dosage | Tenofovir | Atazanavir Sulfate | Adult | Female | Emtricitabine | Adenine - analogs & derivatives | Pyridines - administration & dosage | Double-Blind Method | Ritonavir - administration & dosage | Deoxycytidine - administration & dosage | Adenine - administration & dosage | Organophosphonates - administration & dosage | Quinolones - administration & dosage | HIV Infections - drug therapy | Oligopeptides - administration & dosage | Cobicistat | Deoxycytidine - analogs & derivatives | Drug Combinations | Patient outcomes | Dosage and administration | Research | Comparative analysis | Drug therapy | HIV infection | Anti-HIV agents | Antiretroviral drugs | Bone density | Pharmaceutical industry | Human immunodeficiency virus--HIV | Pneumonia | Laboratories | Ritonavir | Liver | Infections | Drug resistance | Evidence-based medicine | Hepatitis | Randomization | All terrain vehicles | Creatinine | Integrase | Data processing | Proteinase inhibitors | Behavior disorders | Ribonucleic acid--RNA | Patients | Cholesterol | Glomerular filtration rate | Protease inhibitors | Interactive systems | Index Medicus | Abridged Index Medicus
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2. Full Text Effectiveness and Safety of Tenofovir Gel, an Antiretroviral Microbicide, for the Prevention of HIV Infection in Women
by Quarraisha Abdool Karim and Salim S. Abdool Karim and Janet A. Frohlich and Anneke C. Grobler and Cheryl Baxter and Leila E. Mansoor and Ayesha B. M. Kharsany and Sengeziwe Sibeko and Koleka P. Mlisana and Zaheen Omar and Tanuja N. Gengiah and Silvia Maarschalk and Natasha Arulappan and Mukelisiwe Mlotshwa and Lynn Morris and Douglas Taylor and CAPRISA 004 Trial Grp and CAPRISA 004 Trial Group and on behalf of the CAPRISA 004 Trial Group
Science (American Association for the Advancement of Science), ISSN 0036-8075, 9/2010, Volume 329, Issue 5996, pp. 1168 - 1174
Human sexual behavior | HIV infections | Antiinfectives | Gels | HIV | RESEARCH ARTICLES | Placebos | Experimentation | AIDS | Infections | Condoms | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Infectious diseases | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Tropical medicine | Medical sciences | Human viral diseases | HIV Infections - prevention & control | Anti-Infective Agents, Local - therapeutic use | Urban Population - statistics & numerical data | HIV Infections - epidemiology | Humans | Anti-Infective Agents, Local - adverse effects | Drug Resistance, Viral | Administration, Intravaginal | Viral Load | Incidence | Anti-HIV Agents - administration & dosage | Tenofovir | Young Adult | Adenine - adverse effects | HIV-1 - physiology | Adenine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Vaginal Creams, Foams, and Jellies | Rural Population - statistics & numerical data | Sexual Behavior | Adenine - analogs & derivatives | Double-Blind Method | Organophosphonates - therapeutic use | HIV-1 - drug effects | Anti-HIV Agents - adverse effects | South Africa - epidemiology | Organophosphonates - adverse effects | Adenine - administration & dosage | Pregnancy | Organophosphonates - administration & dosage | Anti-Infective Agents, Local - administration & dosage | Adolescent | Patient Compliance | Pregnancy Outcome | Prevention | Anti-infective agents | Research | HIV infection | Index Medicus
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3. Full Text Cobicistat Versus Ritonavir as a Pharmacoenhancer of Atazanavir Plus Emtricitabine/Tenofovir Disoproxil Fumarate in Treatment-Naive HIV Type 1—Infected Patients: Week 48 Results
by Joel E. Gallant and Ellen Koenig and Jaime Andrade-Villanueva and Ploenchan Chetchotisakd and Edwin DeJesus and Francisco Antunes and Keikawus Arastéh and Graeme Moyle and Giuliano Rizzardini and Jan Fehr and Yapei Liu and Lijie Zhong and Christian Callebaut and Javier Szwarcberg and Martin S. Rhee and Andrew K. Cheng
The Journal of infectious diseases, ISSN 0022-1899, 7/2013, Volume 208, Issue 1, pp. 32 - 39
T lymphocytes | HIV/AIDS | Antiretrovirals | Infectious diseases | RNA | HIV | Drug evaluation | AIDS | Photographs | HIV 1 | Virology | cobicistat | pharmacoenhancer | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Humans | Male | Thiazoles - administration & dosage | Carbamates - administration & dosage | Thiazoles - therapeutic use | Oligopeptides - therapeutic use | Anti-HIV Agents - administration & dosage | Tenofovir | Deoxycytidine - therapeutic use | Adenine - therapeutic use | Atazanavir Sulfate | Ritonavir - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Female | Drug Therapy, Combination | Pyridines - therapeutic use | Emtricitabine | Adenine - analogs & derivatives | Pyridines - administration & dosage | Double-Blind Method | Organophosphonates - therapeutic use | Ritonavir - administration & dosage | HIV-1 - drug effects | Deoxycytidine - administration & dosage | Treatment Outcome | HIV Protease Inhibitors - administration & dosage | HIV Protease Inhibitors - therapeutic use | Adenine - administration & dosage | Organophosphonates - administration & dosage | HIV Infections - drug therapy | Oligopeptides - administration & dosage | Carbamates - therapeutic use | Viral Load - drug effects | Cobicistat | Deoxycytidine - analogs & derivatives | Research | Drug therapy | HIV infection | Patient outcomes | Index Medicus | Abridged Index Medicus
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4. Full Text Antiretroviral drug exposure in the female genital tract: Implications for oral pre- and post-exposure prophylaxis
by Dumond, Julie B and Yeh, Rosa F and Patterson, Kristine B and Corbett, Amanda H and Jung, Byung Hwa and Rezk, Naser L and Bridges, Arlene S and Stewart, Paul W and Cohen, Myron S and Kashuba, Angela D.M
AIDS (London), ISSN 0269-9370, 09/2007, Volume 21, Issue 14, pp. 1899 - 1907
Women | Genital tract | HIV | Prophylaxis | Sexual transmission | Pharmacokinetics | Antiretroviral therapy | Infectious Diseases | Immunology | Life Sciences & Biomedicine | Science & Technology | Virology | Antiviral agents | General aspects | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Antibiotics. Antiinfectious agents. Antiparasitic agents | Epidemiology. Vaccinations | Lamivudine - administration & dosage | Humans | Deoxycytidine - blood | Zidovudine - administration & dosage | Tenofovir | Deoxycytidine - pharmacokinetics | HIV Protease Inhibitors - pharmacokinetics | Atazanavir Sulfate | Genitalia, Female - metabolism | Emtricitabine | HIV Infections - blood | HIV Protease Inhibitors - blood | Adenine - analogs & derivatives | Pyridines - administration & dosage | Benzoxazines - administration & dosage | Administration, Oral | Anti-Retroviral Agents - pharmacokinetics | Deoxycytidine - administration & dosage | Lopinavir | HIV Protease Inhibitors - administration & dosage | Adenine - pharmacokinetics | Pyrimidinones - blood | Anti-Retroviral Agents - administration & dosage | Oligopeptides - administration & dosage | Pyrimidinones - administration & dosage | Zidovudine - blood | Deoxycytidine - analogs & derivatives | Reverse Transcriptase Inhibitors - blood | Zidovudine - pharmacokinetics | Pyridines - pharmacokinetics | Reverse Transcriptase Inhibitors - administration & dosage | Adenine - blood | Reverse Transcriptase Inhibitors - pharmacokinetics | Benzoxazines - pharmacokinetics | Adult | Benzoxazines - blood | Female | Organophosphonates - blood | Anti-Retroviral Agents - blood | Drug Therapy, Combination | Oligopeptides - blood | Oligopeptides - pharmacokinetics | Lamivudine - blood | Lamivudine - pharmacokinetics | Adenine - administration & dosage | Organophosphonates - pharmacokinetics | Organophosphonates - administration & dosage | Pyridines - blood | Pyrimidinones - pharmacokinetics | HIV Infections - drug therapy | Index Medicus | AIDS/HIV | genital tract | sexual transmission | antiretroviral therapy | pharmacokinetics | prophylaxis | women
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5. Full Text Rilpivirine versus efavirenz with tenofovir and emtricitabine in treatment-naive adults infected with HIV-1 (ECHO): a phase 3 randomised double-blind active-controlled trial
by Molina, Jean-Michel, Dr, Prof and Cahn, Pedro, MD and Grinsztejn, Beatriz, MD and Lazzarin, Adriano, Prof and Mills, Anthony, MD and Saag, Michael, Prof and Supparatpinyo, Khuanchai, Prof and Walmsley, Sharon, Prof and Crauwels, Herta, PhD and Rimsky, Laurence T, PhD and Vanveggel, Simon, MSc and Boven, Katia, MD and on behalf of the ECHO study group and ECHO Study Grp and ECHO study group
The Lancet (British edition), ISSN 0140-6736, 2011, Volume 378, Issue 9787, pp. 238 - 246
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antiviral agents | General aspects | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Antibiotics. Antiinfectious agents. Antiparasitic agents | Rilpivirine | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | Middle Aged | Male | Anti-HIV Agents - administration & dosage | Nitriles - administration & dosage | Tenofovir | Deoxycytidine - therapeutic use | Adenine - adverse effects | Adenine - therapeutic use | Adult | Anti-HIV Agents - therapeutic use | Deoxycytidine - adverse effects | Female | Reverse Transcriptase Inhibitors - therapeutic use | Acquired Immunodeficiency Syndrome - virology | Acquired Immunodeficiency Syndrome - ethnology | Emtricitabine | Adenine - analogs & derivatives | Benzoxazines - administration & dosage | Double-Blind Method | Drug Administration Schedule | Organophosphonates - therapeutic use | HIV-1 - drug effects | Pyrimidines - administration & dosage | Anti-HIV Agents - adverse effects | Deoxycytidine - administration & dosage | Organophosphonates - adverse effects | Benzoxazines - adverse effects | Treatment Outcome | HIV-1 - genetics | Acquired Immunodeficiency Syndrome - drug therapy | Adenine - administration & dosage | Benzoxazines - therapeutic use | Organophosphonates - administration & dosage | Pyrimidines - therapeutic use | Pyrimidines - adverse effects | Aged | Mutation | Nitriles - adverse effects | Viral Load - drug effects | Deoxycytidine - analogs & derivatives | Nitriles - therapeutic use | Dosage and administration | Efavirenz | Patient outcomes | Clinical trials | Antiretroviral drugs | Drug therapy | Human immunodeficiency virus--HIV | Index Medicus | Abridged Index Medicus
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6. Full Text Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women
by Marrazzo, Jeanne M and Ramjee, Gita and Richardson, Barbra A and Gomez, Kailazarid and Mgodi, Nyaradzo and Nair, Gonasagrie and Palanee, Thesla and Nakabiito, Clemensia and van der Straten, Ariane and Noguchi, Lisa and Hendrix, Craig W and Dai, James Y and Ganesh, Shayhana and Mkhize, Baningi and Taljaard, Marthinette and Parikh, Urvi M and Piper, Jeanna and Mâsse, Benoît and Grossman, Cynthia and Rooney, James and Schwartz, Jill L and Watts, Heather and Marzinke, Mark A and Hillier, Sharon L and McGowan, Ian M and Chirenje, Z. Mike and VOICE Study Team
The New England journal of medicine, ISSN 0028-4793, 02/2015, Volume 372, Issue 6, pp. 509 - 518
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | HIV Infections - prevention & control | Humans | Middle Aged | Drug Resistance, Viral | Administration, Intravaginal | Deoxycytidine - blood | Adenine - blood | Tenofovir | Young Adult | Adenine - adverse effects | Adult | Deoxycytidine - adverse effects | Female | Organophosphonates - blood | Surveys and Questionnaires | Anti-Retroviral Agents - blood | Drug Therapy, Combination | Emtricitabine | Adenine - analogs & derivatives | HIV Seropositivity | Administration, Oral | HIV-1 - drug effects | Deoxycytidine - administration & dosage | Anti-Retroviral Agents - adverse effects | Organophosphonates - adverse effects | Africa South of the Sahara | Adenine - administration & dosage | Pre-Exposure Prophylaxis | Organophosphonates - administration & dosage | Medication Adherence | Anti-Retroviral Agents - administration & dosage | Adolescent | HIV Infections - complications | Deoxycytidine - analogs & derivatives | Women | Care and treatment | HIV infection in women | Dosage and administration | HIV infection | Health aspects | Risk factors | Intervention | Creatinine | Antiretroviral drugs | Motivation | Human immunodeficiency virus--HIV | Prophylaxis | Vagina | Infections | Preventive medicine | Index Medicus | Abridged Index Medicus
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7. Full Text Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3 trial, analysis of results after 48 weeks
by Sax, Paul E, Dr and DeJesus, Edwin, MD and Mills, Anthony, MD and Zolopa, Andrew, Prof and Cohen, Calvin, MD and Wohl, David, MD and Gallant, Joel E, Prof and Liu, Hui C, PhD and Zhong, Lijie, PhD and Yale, Kitty, BA and White, Kirsten, PhD and Kearney, Brian P, Pharm D and Szwarcberg, Javier, MD and Quirk, Erin, MD and Cheng, Andrew K, MD and GS-US-236-0102 Study Team and GS-US-236-0102 study team
The Lancet (British edition), ISSN 0140-6736, 2012, Volume 379, Issue 9835, pp. 2439 - 2448
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Antiviral agents | General aspects | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Antibiotics. Antiinfectious agents. Antiparasitic agents | Emtricitabine | HIV-1 | Adenine - analogs & derivatives | Benzoxazines - administration & dosage | Double-Blind Method | Deoxycytidine - administration & dosage | Humans | Middle Aged | Male | Thiazoles - administration & dosage | Carbamates - administration & dosage | Adenine - administration & dosage | Anti-HIV Agents - administration & dosage | Tenofovir | Organophosphonates - administration & dosage | Quinolones - administration & dosage | Adult | Female | HIV Infections - drug therapy | Cobicistat | Deoxycytidine - analogs & derivatives | Drug Combinations | Patient outcomes | Dosage and administration | Research | Comparative analysis | Drug therapy | HIV infection | Anti-HIV agents | Clinical trials | Antiretroviral drugs | Pharmaceutical industry | Human immunodeficiency virus--HIV | Creatinine | Integrase | Laboratories | Data processing | Infections | Nausea | Ribonucleic acid--RNA | Patients | Efavirenz | Evidence-based medicine | Dreams | Sleep disorders | Hepatitis | Dyspnea | Inhibitors | Protease inhibitors | Insomnia | Suicides & suicide attempts | Index Medicus | Abridged Index Medicus
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8. Full Text Standardized Comparison of the Relative Impacts of HIV-1 Reverse Transcriptase (RT) Mutations on Nucleoside RT Inhibitor Susceptibility
by George L. Melikian and Soo-Yon Rhee and Jonathan Taylor and W. Jeffrey Fessel and David Kaufman and William Towner and Paolo V. Troia-Cancio and Andrew Zolopa and Gregory K. Robbins and Ron Kagan and Dennis Israelski and Robert W. Shafer
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 05/2012, Volume 56, Issue 5, pp. 2305 - 2313
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Immunopathology | Infectious diseases | Pharmacology. Drug treatments | Viral diseases | Viral diseases of the lymphoid tissue and the blood. Aids | Biological and medical sciences | Medical sciences | Human viral diseases | Immunodeficiencies. Immunoglobulinopathies | Immunodeficiencies | Antibiotics. Antiinfectious agents. Antiparasitic agents | Genomics | HIV Reverse Transcriptase - antagonists & inhibitors | Humans | HIV Reverse Transcriptase - genetics | Reverse Transcriptase Inhibitors - administration & dosage | Thymidine - therapeutic use | Zidovudine - administration & dosage | Anti-HIV Agents - administration & dosage | Tenofovir | Thymidine - administration & dosage | Adenine - therapeutic use | HIV-1 - isolation & purification | Anti-HIV Agents - therapeutic use | Dideoxynucleosides - therapeutic use | Nucleosides - genetics | Reverse Transcriptase Inhibitors - therapeutic use | Dideoxynucleosides - administration & dosage | Drug Resistance, Multiple, Viral - drug effects | Adenine - analogs & derivatives | Drug Resistance, Multiple, Viral - genetics | Organophosphonates - therapeutic use | HIV-1 - drug effects | HIV Infections - virology | Genotype | HIV-1 - genetics | Adenine - administration & dosage | Organophosphonates - administration & dosage | Phenotype | Algorithms | Least-Squares Analysis | HIV Infections - drug therapy | Zidovudine - therapeutic use | Mutation | Index Medicus | nucleosides | RNA-directed DNA polymerase | tenofovir | Abacavir | Data processing | Thymidine | Drug resistance | Statistics | Antiviral Agents
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