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Nature communications, ISSN 2041-1723, 2015, Volume 6, Issue 1, p. 6377
Tyrosine kinase inhibitors are effective treatments for non-small-cell lung cancers (NSCLCs... 
GEFITINIB | AMPLIFICATION | GENE | FACTOR RECEPTOR MUTATIONS | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | INHIBITORS | CHEMOTHERAPY | Lung Neoplasms - drug therapy | Recurrence | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Humans | Lung Neoplasms - metabolism | ErbB Receptors - genetics | Gene Expression Regulation, Neoplastic | bcl-X Protein - genetics | Lung Neoplasms - pathology | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | Proto-Oncogene Proteins c-bcl-2 - metabolism | Adenocarcinoma - metabolism | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Lung - metabolism | Gefitinib | ErbB Receptors - deficiency | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | Aniline Compounds - pharmacology | ErbB Receptors - antagonists & inhibitors | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Retinoblastoma Protein - deficiency | Small Cell Lung Carcinoma - genetics | Sulfonamides - pharmacology | Adenocarcinoma - drug therapy | Disease Progression | Drug Resistance, Neoplasm - genetics | Small Cell Lung Carcinoma - pathology | Afatinib | Retinoblastoma Protein - genetics | Erlotinib Hydrochloride - pharmacology | Lung - drug effects | Cell Line, Tumor | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Quinazolines - pharmacology | bcl-X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - genetics | Drug Resistance, Neoplasm - drug effects
Journal Article
Clinical cancer research, ISSN 1078-0432, 03/2018, Volume 24, Issue 5, pp. 1038 - 1047
Journal Article
Journal Article
Nature reviews. Cancer, ISSN 1474-1768, 2007, Volume 7, Issue 10, pp. 778 - 790
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e20351
Background: Squamous cell lung carcinomas account for approximately 25% of new lung carcinoma cases and 40,000 deaths per year in the United States... 
MULTIPLE-MYELOMA | GEFITINIB | GENE | TRASTUZUMAB | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | RESISTANCE | CARCINOMAS | RECEPTOR | OVARIAN-CANCER | ACTIVATING MUTATIONS | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Cell Survival - drug effects | Lung Neoplasms - enzymology | Carcinoma, Non-Small-Cell Lung - genetics | Humans | Genetic Loci - genetics | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | 3' Untranslated Regions - genetics | Lung Neoplasms - pathology | Open Reading Frames - genetics | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Gene Knockdown Techniques | Gene Amplification - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Protein Kinase Inhibitors - pharmacology | Carcinoma, Non-Small-Cell Lung - enzymology | RNA, Small Interfering - metabolism | Care and treatment | Analysis | Oncology, Experimental | Lung cancer, Small cell | Research | Lung cancer, Non-small cell | Health aspects | Cancer | Adenocarcinoma | Lung cancer | Oncology | Single-nucleotide polymorphism | Kinases | Medical schools | Clinical outcomes | Ovarian cancer | Rodents | Fibroblasts | Fibroblast growth factor receptor 1 | Growth factors | Squamous cell carcinoma | Small cell lung carcinoma | Non-small cell lung carcinoma | Lung carcinoma | Bladder cancer | Patients | Esophagus | Amplification | Chromosome 8 | Mutation | Fibroblast growth factor receptors | Tumors
Journal Article
The lancet oncology, ISSN 1470-2045, 2015, Volume 16, Issue 2, pp. 141 - 151
Journal Article
International journal of radiation oncology, biology, physics, ISSN 0360-3016, 2014, Volume 89, Issue 5, pp. 1084 - 1091
.... We sought to investigate the mechanisms underlying radiation-induced lymphopenia and its associations with patient outcomes in non-small cell lung cancer (NSCLC... 
Radiology | Hematology, Oncology and Palliative Medicine | SURVIVAL | IMMUNE | CTLA-4 BLOCKADE | MELANOMA | ONCOLOGY | MARKER | LOCAL RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | IN-SITU VACCINATION | T-CELLS | Carcinoma, Non-Small-Cell Lung - radiotherapy | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Lung Neoplasms - mortality | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Lung Neoplasms - radiotherapy | Lung Neoplasms - pathology | Male | Carcinoma, Squamous Cell - radiotherapy | Lymphopenia - etiology | Lymphopenia - mortality | Carcinoma, Squamous Cell - mortality | Aged, 80 and over | Adult | Female | Lung - radiation effects | Adenocarcinoma - radiotherapy | Lymphopenia - diagnosis | Carcinoma, Non-Small-Cell Lung - pathology | Radiotherapy Dosage | Lung - pathology | Treatment Outcome | Tumor Burden | Adenocarcinoma - drug therapy | Carcinoma, Non-Small-Cell Lung - mortality | Carcinoma, Non-Small-Cell Lung - immunology | Disease-Free Survival | Regression Analysis | Lung Neoplasms - immunology | Carcinoma, Squamous Cell - drug therapy | Aged | Carcinoma, Non-Small-Cell Lung - drug therapy | Adenocarcinoma - mortality | Care and treatment | Patient outcomes | Immunotherapy | Lung cancer, Small cell | Lung cancer, Non-small cell | Lymphocytopenia | Tumors | Chemotherapy | Lymphocytes | Analysis | Radiation | Cancer | PATIENTS | LYMPHOPENIA | NEOPLASMS | LUNGS | MONOCYTES | NEUTROPHILS | CORRELATIONS | RADIATION DOSES | CHEMOTHERAPY | MULTIVARIATE ANALYSIS | RADIOLOGY AND NUCLEAR MEDICINE | RADIOTHERAPY | LYMPHOCYTES
Journal Article
PloS one, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e59314
Background: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKI), gefitinib and erlotinib have been tested as maintenance therapy in patients with advanced non-small-cell lung cancer... 
PHASE-III TRIAL | 1ST-LINE TREATMENT | PLACEBO | MULTICENTER | CARBOPLATIN | CISPLATIN | MULTIDISCIPLINARY SCIENCES | DOUBLE-BLIND | OPEN-LABEL | CHEMOTHERAPY | GEMCITABINE | Erlotinib Hydrochloride | Lung Neoplasms - drug therapy | Adenocarcinoma - pathology | Prognosis | Lung Neoplasms - mortality | Humans | Middle Aged | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Lung - enzymology | Carcinoma, Non-Small-Cell Lung - pathology | Lung - pathology | Lung Neoplasms - enzymology | Adenocarcinoma - enzymology | Adenocarcinoma - drug therapy | Carcinoma, Non-Small-Cell Lung - mortality | Randomized Controlled Trials as Topic | Protein Kinase Inhibitors - therapeutic use | Quinazolines - therapeutic use | Lung - drug effects | Survival Analysis | Carcinoma, Non-Small-Cell Lung - drug therapy | Carcinoma, Non-Small-Cell Lung - enzymology | Neoplasm Staging | Adenocarcinoma - mortality | Tyrosine | Complications and side effects | Care and treatment | Chemotherapy | Erlotinib | Analysis | Oncology, Experimental | Lung cancer, Small cell | Research | Lung cancer, Non-small cell | Gefitinib | Cancer | Adenocarcinoma | Toxicity | Lung cancer | Clinical trials | Oncology | Population studies | Systematic review | Statistical methods | Cancer therapies | Subgroups | Confidence intervals | Epidermal growth factor | Protein-tyrosine kinase | Statistical analysis | Small cell lung carcinoma | Epidermal growth factor receptors | Oral administration | Non-small cell lung carcinoma | Histology | Maintenance | Minority & ethnic groups | Patients | Survival | Studies | Hospitals | Mutation | Smoking
Journal Article