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Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2724 - 13
Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that... 
TGF-BETA | MELANOMA | THERAPY | MEMORY | CANCER REGRESSION | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | PD-1 | EXPRESSION | EXHAUSTION | ANTIGEN | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Adenocarcinoma of Lung - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Squamous Cell Carcinoma of Head and Neck - pathology | Ovarian Neoplasms - pathology | Transcriptome | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Squamous Cell Carcinoma of Head and Neck - mortality | Ovarian Neoplasms - mortality | Antigens, CD - genetics | Squamous Cell Carcinoma of Head and Neck - immunology | Ovarian Neoplasms - genetics | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Carcinoma, Squamous Cell - mortality | Melanoma - genetics | Integrin alpha Chains - immunology | Female | Adenocarcinoma of Lung - immunology | Apyrase - immunology | Immunophenotyping | Melanoma - pathology | Carcinoma, Squamous Cell - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | CD8 Antigens - immunology | Squamous Cell Carcinoma of Head and Neck - genetics | Lymphocytes, Tumor-Infiltrating - pathology | Melanoma - immunology | Apyrase - genetics | CD8 Antigens - genetics | Survival Analysis | CD8-Positive T-Lymphocytes - immunology | Integrin alpha Chains - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Melanoma - mortality | Ovarian Neoplasms - immunology | Head | Phenotypes | Tumor cells | CD8 antigen | T cell receptors | Lymphocytes T | Patients | Metastases | T-cell receptor | CD103 antigen | Major histocompatibility complex | Lymphocytes | Immunotherapy | Head and neck cancer | Neck | Solid tumors | Cancer | Tumors | BASIC BIOLOGICAL SCIENCES
Journal Article
Cell Metabolism, ISSN 1550-4131, 04/2018, Volume 27, Issue 4, pp. 935 - 943.e4
Journal Article
Clinical Immunology, ISSN 1521-6616, 02/2018, Volume 187, pp. 37 - 45
Journal Article
Anticancer Research, ISSN 0250-7005, 04/2019, Volume 39, Issue 4, pp. 1923 - 1926
Case Report: Case 1 of an investigator-initiated study using oral single agent mifepristone to halt stage IV non-small cell lung cancer whose tumor was devoid... 
Mifepristone | Check-point inhibitor | Progesterone induced blocking factor | Programmed death factor-ligand 1 | Progesterone receptor modulator | Non-small cell lung cancer | check-point inhibitor | SURVIVAL | EFFICACY | mifepristone | PROGESTERONE-RECEPTOR ANTAGONIST | INDUCED BLOCKING FACTOR | THERAPY | ONCOLOGY | progesterone receptor modulator | IMMUNOTHERAPY | AGENT MIFEPRISTONE | programmed death factor-ligand 1 | BLOCKADE | progesterone induced blocking factor | PD-1 | TREATMENT IMPROVES LENGTH | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - drug therapy | Adenocarcinoma of Lung - pathology | Humans | Lung Neoplasms - pathology | Nivolumab - therapeutic use | Treatment Outcome | B7-H1 Antigen - immunology | Disease Progression | Carcinoma, Non-Small-Cell Lung - immunology | Lung Neoplasms - immunology | B7-H1 Antigen - antagonists & inhibitors | Time Factors | Antineoplastic Agents, Immunological - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adenocarcinoma of Lung - drug therapy | Quality of Life | Female | Aged | Adenocarcinoma of Lung - immunology | Carcinoma, Non-Small-Cell Lung - drug therapy | Neoplasm Staging | Mifepristone - therapeutic use | Multiagent systems | Lung cancer | Lung diseases | Non-small cell lung carcinoma | Cancer therapies | Quality of life | Metastases | Chemotherapy | Inhibitors | PD-L1 protein | Obstructive lung disease | Chronic obstructive pulmonary disease | Tumors | Apoptosis
Journal Article
International Journal of Cancer, ISSN 0020-7136, 08/2018, Volume 143, Issue 4, pp. 931 - 943
IFN‐γ plays a crucial role in anti‐tumor responses and also induces expression of PD‐L1, a well‐established inhibitor of anti‐tumor immune function.... 
IFNG | PI3K | STAT1 | lung adenocarcinoma | PD‐L1 | PD-L1 | TARGET | CELLS | ACTIVATION | PHOSPHORYLATION | TUMOR-DEVELOPMENT | EGFR | THERAPY | INTERFERON-GAMMA | ONCOLOGY | PATHWAY | RESISTANCE | Phosphorylation | Prognosis | Adenocarcinoma of Lung - pathology | Humans | Lung Neoplasms - metabolism | Transcriptome | Tumor Microenvironment | Lung Neoplasms - pathology | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | STAT1 Transcription Factor - metabolism | Adenocarcinoma of Lung - genetics | Janus Kinase 2 - metabolism | Transcription, Genetic | Adenocarcinoma of Lung - immunology | Proto-Oncogene Proteins c-akt - metabolism | STAT3 Transcription Factor - metabolism | Lung Neoplasms - genetics | T-Lymphocytes, Cytotoxic - immunology | Signal Transduction | Interferon-gamma - physiology | B7-H1 Antigen - metabolism | Lung Neoplasms - immunology | Cell Line, Tumor | Adenocarcinoma of Lung - metabolism | Adenocarcinoma | Lung cancer | Crosstalk | Cytotoxicity | AKT protein | Lymphocytes T | Signal transduction | Pathways | Lymphocytes | Immunotherapy | Janus kinase 2 | Cell cycle | Bioindicators | Inhibition | Stat1 protein | Sensitivity analysis | Immune response | Tumor cells | Gene expression | Patients | Molecular chains | 1-Phosphatidylinositol 3-kinase | Signaling | Biomarkers | Interferon | Combinatorial analysis | Cancer | Tumors
Journal Article
BMC Genomics, ISSN 1471-2164, 08/2018, Volume 19, Issue 1, pp. 582 - 9
Journal Article