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Human Pathology, ISSN 0046-8177, 09/2018, Volume 79, pp. 188 - 198
The presence of tumor-infiltrating lymphocytes (TILs) positively impacts the outcome of non–small cell lung cancer (NSCLC) patients. Most previous studies have... 
Prognosis | TILs | Tumor-infiltrating lymphocytes | NSCLC | Lung cancer | Immunoscore | REVISION | CLASSIFICATION | PATHOLOGY | DENSITY | TNM STAGE GROUPINGS | PROPOSALS | RECOMMENDATIONS | RECURRENCE | EDITION | Staining and Labeling - methods | Predictive Value of Tests | Adenocarcinoma of Lung - pathology | Lung Neoplasms - mortality | Stromal Cells - pathology | Carcinoma, Squamous Cell - pathology | Coloring Agents | Humans | Middle Aged | Carcinoma, Squamous Cell - surgery | Lung Neoplasms - pathology | Male | Pneumonectomy | Adenocarcinoma of Lung - mortality | Carcinoma, Squamous Cell - mortality | Time Factors | Hematoxylin | Female | Retrospective Studies | Adenocarcinoma of Lung - immunology | Carcinoma, Non-Small-Cell Lung - pathology | Reproducibility of Results | Carcinoma, Non-Small-Cell Lung - surgery | Risk Factors | Stromal Cells - immunology | Adenocarcinoma of Lung - surgery | Carcinoma, Non-Small-Cell Lung - mortality | Carcinoma, Squamous Cell - immunology | Carcinoma, Non-Small-Cell Lung - immunology | Disease-Free Survival | Lung Neoplasms - immunology | Lymphocytes, Tumor-Infiltrating - pathology | Lung Neoplasms - surgery | Aged | Neoplasm Staging | Observer Variation | Eosine Yellowish-(YS) | Lymphocytes, Tumor-Infiltrating - immunology | Medical research | Squamous cell carcinoma | Lymphocytes | Patient outcomes | Analysis | Medicine, Experimental | Lung cancer, Small cell | Lung cancer, Non-small cell | Tumors | Studies | Chemotherapy | Medical prognosis | Classification | Breast cancer | Patients
Journal Article
Cell, ISSN 0092-8674, 02/2018, Volume 172, Issue 4, pp. 857 - 868.e15
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2018, Volume 13, Issue 6, p. e0198634
In this study, we present the clinicopathological features associated with PD-L1 protein and mRNA expression in a large Asian cohort of patients with non-small... 
PEMBROLIZUMAB | METAANALYSIS | SAFETY | PD-L1 EXPRESSION | MULTIDISCIPLINARY SCIENCES | ANTIBODY | PULMONARY ADENOCARCINOMA | NIVOLUMAB | DOCETAXEL | DRIVER MUTATIONS | IMMUNOHISTOCHEMISTRY | Prognosis | Follow-Up Studies | Adenocarcinoma of Lung - pathology | Lung Neoplasms - mortality | Proto-Oncogene Proteins p21(ras) - genetics | Tissue Array Analysis | Humans | Middle Aged | Asian Continental Ancestry Group - genetics | ErbB Receptors - genetics | Lung Neoplasms - pathology | Male | RNA, Messenger - metabolism | Anaplastic Lymphoma Kinase - genetics | Young Adult | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Aged, 80 and over | Adult | Female | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | Carcinoma, Non-Small-Cell Lung - genetics | B7-H1 Antigen - genetics | Carcinoma, Non-Small-Cell Lung - mortality | B7-H1 Antigen - metabolism | Gene Rearrangement | Survival Analysis | Aged | Mutation | Messenger RNA | Genetic aspects | Research | Gene expression | Lung cancer, Non-small cell | Apoptosis | Adenocarcinoma | Immunohistochemistry | Lung cancer | Clinical trials | Cancer therapies | Subgroups | Proteins | Medical research | Squamous cell carcinoma | Immunoglobulins | Epidermal growth factor receptors | Tumor cells | Non-small cell lung carcinoma | L1 protein | Histology | Ribonucleic acid--RNA | Studies | Pathology | Hospitals | Cell death | MicroRNAs | PD-L1 protein | Biomarkers | Ligands | Cancer | Tumors | RNA | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2018, Volume 13, Issue 7, p. e0200633
Purpose Lung cancer is the deadliest known cancer in the world, with the highest number of mutations in proto-oncogenes and tumor suppressor genes. Therefore,... 
MOLECULAR-PATHOLOGY | POLYMERASE-CHAIN-REACTION | METAANALYSIS | JOINT-CONSENSUS-RECOMMENDATION | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | SQUAMOUS-CELL CARCINOMA | SEQUENCE VARIANTS | ASSOCIATION | EXPRESSION | P53 | Adenocarcinoma of Lung - pathology | Proto-Oncogene Proteins p21(ras) - genetics | Carcinoma, Large Cell - pathology | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Tumor Suppressor Protein p53 - genetics | Adenocarcinoma of Lung - genetics | Iran | DNA Mutational Analysis | Aged, 80 and over | Adult | Female | Carcinoma, Large Cell - genetics | Discoidin Domain Receptor 2 - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Lung - pathology | Carcinoma, Non-Small-Cell Lung - genetics | Exons - genetics | Small Cell Lung Carcinoma - genetics | Small Cell Lung Carcinoma - pathology | Aged | Mutation | Care and treatment | Cancer patients | Gene mutations | Analysis | Genetic research | Genetic aspects | Research | Lung cancer, Non-small cell | Health aspects | Cancer | Adenocarcinoma | Exons | p53 Protein | Genes | Lung cancer | Oncology | Kinases | Cancer therapies | Gene sequencing | Cell growth | Cell cycle | Medical research | Squamous cell carcinoma | Non-small cell lung carcinoma | Gene expression | Patients | Medicine | Experimental design | Medical prognosis | Stem cells | Tumor suppressor genes | Molecular biology | Variation | Design of experiments | Apoptosis | Proto-oncogenes
Journal Article
by Zhang, J and Deng, H and Wu, CC and Wang, ZY and Zhao, DH and Wei, B and Zhang, JY and Tong, XJ and Gao, J and Pan, L and Xue, XY
MEDICINE, ISSN 0025-7974, 04/2019, Volume 98, Issue 14, p. e15031
Journal Article
Cancer Research, ISSN 0008-5472, 06/2018, Volume 78, Issue 12, pp. 3207 - 3219
The long noncoding RNA (lncRNA) MIR22HG has previously been identified as a prognostic marker in hepatocellular carcinoma. Here, we performed a comprehensive... 
YB-1 | ONCOLOGY | LANDSCAPE | BOX-BINDING PROTEIN-1 | POOR-PROGNOSIS | GENE-EXPRESSION | PROGNOSTIC MARKER | SENESCENCE | PROLIFERATION | INHIBITORS | PROGRESSION | Proto-Oncogene Proteins c-met - metabolism | Follow-Up Studies | Adenocarcinoma of Lung - pathology | Lung Neoplasms - mortality | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Cell Survival - genetics | Lung Neoplasms - pathology | Male | MicroRNAs - metabolism | Pneumonectomy | Gene Knockdown Techniques | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Y-Box-Binding Protein 1 - genetics | Lung Neoplasms - genetics | Lung - pathology | Datasets as Topic | Down-Regulation | Signal Transduction - genetics | Adenocarcinoma of Lung - surgery | Y-Box-Binding Protein 1 - metabolism | Survival Analysis | Cell Line, Tumor | Lung Neoplasms - surgery | Aged | MicroRNAs - genetics | Lung - surgery | Apoptosis | Cell proliferation | Cell survival | Therapeutic applications | RNA-mediated interference | Lung cancer | Hepatocellular carcinoma | Tumor cell lines | Gene expression | Ribonucleic acid--RNA | Survival | c-Met protein | Proteins | Signaling | Cyclin-dependent kinase inhibitor p21 | Cell death | Cell lines | Cell cycle | Tumor suppressor genes | Diagnostic systems | Cancer | Tumors
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 2724 - 13
Identifying tumor antigen-specific T cells from cancer patients has important implications for immunotherapy diagnostics and therapeutics. Here, we show that... 
TGF-BETA | MELANOMA | THERAPY | MEMORY | CANCER REGRESSION | INFILTRATING LYMPHOCYTES | MULTIDISCIPLINARY SCIENCES | PD-1 | EXPRESSION | EXHAUSTION | ANTIGEN | Antigens, CD - immunology | CD8-Positive T-Lymphocytes - pathology | Adenocarcinoma of Lung - pathology | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Squamous Cell Carcinoma of Head and Neck - pathology | Ovarian Neoplasms - pathology | Transcriptome | Male | Receptors, Antigen, T-Cell, alpha-beta - immunology | Squamous Cell Carcinoma of Head and Neck - mortality | Ovarian Neoplasms - mortality | Antigens, CD - genetics | Squamous Cell Carcinoma of Head and Neck - immunology | Ovarian Neoplasms - genetics | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Carcinoma, Squamous Cell - mortality | Melanoma - genetics | Integrin alpha Chains - immunology | Female | Adenocarcinoma of Lung - immunology | Apyrase - immunology | Immunophenotyping | Melanoma - pathology | Carcinoma, Squamous Cell - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | CD8 Antigens - immunology | Squamous Cell Carcinoma of Head and Neck - genetics | Lymphocytes, Tumor-Infiltrating - pathology | Melanoma - immunology | Apyrase - genetics | CD8 Antigens - genetics | Survival Analysis | CD8-Positive T-Lymphocytes - immunology | Integrin alpha Chains - genetics | Lymphocytes, Tumor-Infiltrating - immunology | Melanoma - mortality | Ovarian Neoplasms - immunology | Head | Phenotypes | Tumor cells | CD8 antigen | T cell receptors | Lymphocytes T | Patients | Metastases | T-cell receptor | CD103 antigen | Major histocompatibility complex | Lymphocytes | Immunotherapy | Head and neck cancer | Solid tumors | Cancer | Tumors | BASIC BIOLOGICAL SCIENCES
Journal Article
Journal Article
International Journal of Cancer, ISSN 0020-7136, 06/2018, Volume 142, Issue 12, pp. 2589 - 2598
Journal Article
The Annals of Thoracic Surgery, ISSN 0003-4975, 07/2018, Volume 106, Issue 1, pp. 214 - 220
Journal Article
Cancer, ISSN 0008-543X, 06/2018, Volume 124, Issue 11, pp. 2399 - 2406
BACKGROUND Two or more different epidermal growth factor receptor (EGFR) mutations can be detected within a single tumor sample, which represents complex... 
tyrosine kinase inhibitors | non–small cell lung cancer | epidermal growth factor receptor | complex mutations | lung adenocarcinoma | non-small cell lung cancer | MULTICENTER | RARE | GEFITINIB TREATMENT | SOMATIC MUTATIONS | CHEMOTHERAPY | GENE | ONCOLOGY | UNCOMMON EGFR MUTATIONS | CANCER STATISTICS | PATIENT | ERLOTINIB | Lung Neoplasms - drug therapy | Follow-Up Studies | Adenocarcinoma of Lung - pathology | Lung Neoplasms - mortality | Humans | Middle Aged | ErbB Receptors - genetics | Lung Neoplasms - pathology | Male | Response Evaluation Criteria in Solid Tumors | Tomography, X-Ray Computed | Antineoplastic Agents - therapeutic use | Lung - diagnostic imaging | Adenocarcinoma of Lung - mortality | Adenocarcinoma of Lung - genetics | Adenocarcinoma of Lung - drug therapy | Adult | Female | Antineoplastic Agents - pharmacology | Retrospective Studies | Lung Neoplasms - genetics | Lung - pathology | ErbB Receptors - antagonists & inhibitors | Kaplan-Meier Estimate | Exons - genetics | Drug Resistance, Neoplasm - genetics | Biopsy | Protein Kinase Inhibitors - therapeutic use | Progression-Free Survival | Aged | Protein Kinase Inhibitors - pharmacology | Mutation | Adenocarcinoma | Tyrosine | Care and treatment | Usage | Research | Prevalence studies (Epidemiology) | Confidence intervals | Epidermal growth factor | Epidermal growth factor receptors | Lungs | Patients | Protein-tyrosine kinase | Cancer
Journal Article