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Clinical Cancer Research, ISSN 1078-0432, 02/2003, Volume 9, Issue 2, pp. 802 - 811
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65158
Cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) are defined as a small population of cancer cells that have high tumorigenicity. Furthermore,... 
POPULATION | ALDEHYDE DEHYDROGENASE | MARKER | MULTIDISCIPLINARY SCIENCES | CARCINOMAS | CD133 EXPRESSION | DEFINES | DRUG-RESISTANCE | IDENTIFICATION | TUMORIGENESIS | TUMOR-INITIATING CELLS | Prognosis | Humans | Middle Aged | Retinal Dehydrogenase - metabolism | Ovarian Neoplasms - pathology | Cystadenocarcinoma, Serous - genetics | Cystadenocarcinoma, Serous - pathology | Ovarian Neoplasms - genetics | Neoplastic Stem Cells - metabolism | Isoenzymes - metabolism | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Adult | Female | Gene Expression | Isoenzymes - genetics | Ovarian Neoplasms - diagnosis | Adenocarcinoma, Clear Cell - diagnosis | Retinal Dehydrogenase - genetics | Organ Specificity | Ovarian Neoplasms - enzymology | Cystadenocarcinoma, Serous - enzymology | Cell Line, Tumor | Adenocarcinoma, Clear Cell - pathology | Aged | Biomarkers, Tumor - genetics | Cystadenocarcinoma, Serous - diagnosis | Primary Cell Culture | Neoplasm Staging | Adenocarcinoma, Clear Cell - enzymology | Adenocarcinoma, Clear Cell - genetics | Adenocarcinoma | Immunohistochemistry | Medical colleges | Relapse | Oncology, Experimental | Development and progression | Research | Ovarian cancer | Diseases | Chemotherapy | Analysis | Cancer | Biotechnology | Ovarian carcinoma | Colorectal cancer | Metastasis | Aldehyde dehydrogenase | Metastases | Population | Invasiveness | Mortality | Gynecology | Tumorigenicity | Tumor cell lines | Gene expression | Obstetrics | Medicine | Studies | Pathology | Hospitals | Cell lines | Stem cells | Biomarkers
Journal Article
Biochemical Journal, ISSN 0264-6021, 08/2004, Volume 381, Issue 3, pp. 761 - 767
An important regulator involved in oxygen-dependent gene expression is the transcription factor HIF (hypoxia-inducible factor), which is composed of an... 
Post-translational modification | Hypoxia-inducible factor | Protein degradation | Oxygen sensing | Prolyl hydroxylation | Von-Hippel-Lindau protein | TRANSCRIPTIONAL ACTIVITY | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA | hypoxia-inducible factor | oxygen sensing | post-translational modification | von-Hippel-Lindau protein | FAMILY | OXYGEN | FACTOR-1-ALPHA | GENE-EXPRESSION | HIF-1-ALPHA | VHL | protein degradation | prolyl hydroxylation | Humans | Half-Life | Kidney Neoplasms - metabolism | Ubiquitin-Protein Ligases - physiology | Bone Neoplasms - pathology | Hypoxia-Inducible Factor 1, alpha Subunit | RNA, Messenger - biosynthesis | Liver Neoplasms - pathology | Liver Neoplasms - enzymology | Kidney Tubules, Proximal - cytology | DNA-Binding Proteins - physiology | Hypoxia - enzymology | Hydroxylation | Hypoxia-Inducible Factor 1 | Immediate-Early Proteins - biosynthesis | Carcinoma, Hepatocellular - enzymology | Tumor Suppressor Proteins - physiology | Epithelial Cells - enzymology | Liver Neoplasms - metabolism | Cell Line, Tumor | Von Hippel-Lindau Tumor Suppressor Protein | Enzyme Induction - physiology | Osteosarcoma - pathology | Carcinoma, Hepatocellular - metabolism | Epithelial Cells - metabolism | Gene Expression Regulation, Enzymologic - physiology | Oxygen - metabolism | Procollagen-Proline Dioxygenase - biosynthesis | Bone Neoplasms - metabolism | Procollagen-Proline Dioxygenase - metabolism | DNA-Binding Proteins - metabolism | Kidney Tubules, Proximal - enzymology | Gene Expression Regulation, Neoplastic - physiology | Osteosarcoma - metabolism | Cell Line | Transcription Factors - physiology | Bone Neoplasms - enzymology | Osteosarcoma - enzymology | Adenocarcinoma, Clear Cell - metabolism | Nuclear Proteins - metabolism | Hypoxia-Inducible Factor-Proline Dioxygenases | Dioxygenases | Transcription Factors - metabolism | Kidney Neoplasms - enzymology | Carcinoma, Hepatocellular - pathology | Kidney Tubules, Proximal - metabolism | Kidney Neoplasms - pathology | Adenocarcinoma, Clear Cell - pathology | Nuclear Proteins - physiology | Adenocarcinoma, Clear Cell - enzymology | DNA-Binding Proteins - biosynthesis | ODD, oxygen-dependent degradation domain | aRP, acidic ribosomal protein | RNAi, RNA interference | pVHL, von-Hippel-Lindau protein | EGLN, egg-laying deficient nine-like protein | HIF, hypoxia-inducible factor | siRNA, small interfering RNA | IVTT, in vitro transcription | PHD, prolyl hydroxylase domain containing protein | translation | RT, reverse transcriptase | RPTEC, human renal proximal tubular epithelial cells
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 04/2009, Volume 15, Issue 7, pp. 2269 - 2280
Journal Article
Cancer Research, ISSN 0008-5472, 08/2008, Volume 68, Issue 16, pp. 6541 - 6549
Journal Article
The Journal of Pathology, ISSN 0022-3417, 03/2014, Volume 232, Issue 4, pp. 473 - 481
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 07/2018, Volume 119, Issue 7, pp. 6008 - 6015
Journal Article
Journal Article
International Journal of Gynecologic Cancer, ISSN 1048-891X, 10/2017, Volume 27, Issue 8, pp. 1666 - 1674
ObjectiveThis study aims to clarify the incidence of Aurora kinase A (Aurora-A) protein expression and its correlation with clinical parameters in ovarian... 
Clear cell | Tissue microarray | Aurora-A | Targeted therapy | Ovarian cancer | targeted therapy | ENMD-2076 | ovarian cancer | tissue microarray | clear cell | CANCER | CHEMOTHERAPY | OBSTETRICS & GYNECOLOGY | OVEREXPRESSION | AMPLIFICATION | GENE | MODELS | ONCOLOGY | POOR-PROGNOSIS | CHEMORESISTANCE | Immunohistochemistry | Paclitaxel - pharmacology | Prognosis | Apoptosis - drug effects | Tissue Array Analysis | Humans | Middle Aged | Aurora Kinase A - antagonists & inhibitors | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cisplatin - administration & dosage | G2 Phase Cell Cycle Checkpoints - drug effects | Adult | Camptothecin - administration & dosage | Female | Biomarkers, Tumor - antagonists & inhibitors | Paclitaxel - administration & dosage | Ovarian Neoplasms - drug therapy | Camptothecin - analogs & derivatives | Doxorubicin - administration & dosage | Pyrazoles - pharmacology | M Phase Cell Cycle Checkpoints - drug effects | Cisplatin - pharmacology | Pyrimidines - pharmacology | Ovarian Neoplasms - enzymology | Drug Synergism | Protein Kinase Inhibitors - administration & dosage | Aurora Kinase A - biosynthesis | Cell Line, Tumor | Ki-67 Antigen - biosynthesis | Aged | Protein Kinase Inhibitors - pharmacology | Adenocarcinoma, Clear Cell - enzymology | Camptothecin - pharmacology | Biomarkers, Tumor - biosynthesis | Doxorubicin - pharmacology | Adenocarcinoma, Clear Cell - drug therapy
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 12/2009, Volume 33, Issue 12, pp. 1869 - 1877
Endometrial carcinomas (ECs) in Young women (<= 40 y) are Usually managed conservatively in selected patients. Whether oophorectomy with total hysterectomy is... 
HNPCC/Lynch syndrome | Endometrial carcinoma | Young patients | SURGERY | FERTILITY-PRESERVING TREATMENT | LYNCH-SYNDROME | NONPOLYPOSIS COLORECTAL-CANCER | SYNCHRONOUS PRIMARY CANCERS | PROGESTERONE-RECEPTORS | PROMOTER METHYLATION | MICROSATELLITE INSTABILITY | endometrial carcinoma | CLINICAL-FEATURES | OVARIAN-CANCER | PATHOLOGY | ESTROGEN-RECEPTOR-ALPHA | Immunohistochemistry | MutL Protein Homolog 1 | Nuclear Proteins - analysis | Age Factors | Endometrial Neoplasms - mortality | Adenocarcinoma, Clear Cell - mortality | Humans | Ovarian Neoplasms - pathology | DNA-Binding Proteins - analysis | Neoplasms, Multiple Primary | Ovarian Neoplasms - mortality | Carcinoma, Endometrioid - therapy | Patient Selection | Ovarian Neoplasms - genetics | Young Adult | Endometrial Neoplasms - genetics | Time Factors | Adenosine Triphosphatases - analysis | DNA Mismatch Repair | Adult | Female | Mismatch Repair Endonuclease PMS2 | Carcinoma, Endometrioid - genetics | Endometrial Neoplasms - enzymology | Carcinoma, Endometrioid - enzymology | Risk Assessment | Down-Regulation | Risk Factors | Treatment Outcome | DNA Repair Enzymes - analysis | Ovarian Neoplasms - enzymology | Adaptor Proteins, Signal Transducing - analysis | Biopsy | Carcinoma, Endometrioid - mortality | Adenocarcinoma, Clear Cell - therapy | Endometrial Neoplasms - therapy | Ovarian Neoplasms - therapy | Endometrial Neoplasms - pathology | Adenocarcinoma, Clear Cell - pathology | MutS Homolog 2 Protein - analysis | Neoplasm Staging | Adenocarcinoma, Clear Cell - enzymology | Adenocarcinoma, Clear Cell - genetics | Carcinoma, Endometrioid - pathology
Journal Article