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Journal Article
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 08/2006, Volume 46, Issue 8, pp. 876 - 886
Journal Article
Journal of Bacteriology, ISSN 0021-9193, 07/2007, Volume 189, Issue 14, pp. 5049 - 5059
Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
ORAL STREPTOCOCCI | METABOLISM | TAGATOSE 6-PHOSPHATE PATHWAY | GLUCOSE | ENZYME-II | SUCROSE | GENE-EXPRESSION | MICROBIOLOGY | PHOSPHOTRANSFERASE SYSTEM | PHOSPHOENOLPYRUVATE | NUCLEOTIDE-SEQUENCE | Raffinose - pharmacokinetics | Galactose - metabolism | Phosphoenolpyruvate Sugar Phosphotransferase System - physiology | Carbohydrates - pharmacokinetics | Gene Expression Profiling | Streptococcus mutans - genetics | Sucrose - pharmacokinetics | ATP-Binding Cassette Transporters - physiology | Fructose - metabolism | Mannose - metabolism | Lactose - metabolism | ATP-Binding Cassette Transporters - genetics | Sucrose - metabolism | ATP-Binding Cassette Transporters - metabolism | Transcription, Genetic | Biological Transport - genetics | Trisaccharides - metabolism | Phosphoenolpyruvate Sugar Phosphotransferase System - genetics | Oligosaccharides - pharmacokinetics | Galactose - pharmacokinetics | Lactose - pharmacokinetics | Maltose - metabolism | Streptococcus mutans - metabolism | Fructose - pharmacokinetics | Oligonucleotide Array Sequence Analysis - methods | Cellobiose - metabolism | Oligosaccharides - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Cellobiose - pharmacokinetics | Maltose - pharmacokinetics | Mannose - pharmacokinetics | Glucose - pharmacokinetics | Phosphoenolpyruvate Sugar Phosphotransferase System - metabolism | Glucose - metabolism | Trisaccharides - pharmacokinetics | Gene Expression Regulation, Bacterial | Raffinose - metabolism | Genetic aspects | Adenosine triphosphatase genes | Research | Genetic transcription | Phosphotransferases | Streptococcus mutans | Genetics and Molecular Biology
Journal Article
Clinical Therapeutics, ISSN 0149-2918, 02/2018, Volume 40, Issue 2, pp. 309 - 319
Journal Article
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 02/2019, Volume 83, Issue 2, pp. 319 - 328
PurposeVeliparib is an oral inhibitor of poly(ADP-ribose) polymerase enzyme. Combination of veliparib and temozolomide was well-tolerated and demonstrated... 
Pharmacometrics | Exposure-response | Temozolomide | Veliparib | CANCER | PARP INHIBITOR | PREDICTION | TRIAL | POLYMERASE INHIBITOR ABT-888 | DNA-DAMAGING AGENTS | ONCOLOGY | OCT2 | TOPOTECAN | MASS | PHARMACOLOGY & PHARMACY | DRUG-DRUG INTERACTIONS | Prognosis | Follow-Up Studies | Temozolomide - pharmacokinetics | Humans | Middle Aged | Male | Antineoplastic Agents, Alkylating - administration & dosage | Incidence | Tissue Distribution | Young Adult | Benzimidazoles - administration & dosage | Aged, 80 and over | Leukemia, Myeloid, Acute - drug therapy | Adult | Female | Mucositis - epidemiology | Drug Therapy, Combination | Maryland - epidemiology | Leukemia, Myeloid, Acute - pathology | Poly(ADP-ribose) Polymerase Inhibitors - pharmacokinetics | Benzimidazoles - pharmacokinetics | Antineoplastic Agents, Alkylating - pharmacokinetics | Models, Statistical | Mucositis - chemically induced | Poly(ADP-ribose) Polymerase Inhibitors - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Temozolomide - administration & dosage | Aged | Antimitotic agents | Enzymes | Medical research | Analysis | Medicine, Experimental | Antineoplastic agents | Sugars | Monosaccharides | Creatinine | Mucositis | Toxicity | Myeloid leukemia | Leukemia | Body weight | Oral administration | Poly(ADP-ribose) | Poly(ADP-ribose) polymerase | Adenosine diphosphate | Pharmacology | Exposure | Dosage | Survival | Patients | Optimization | Polymerase | Body mass | Ribose | Safety engineering | Safety | Pharmacokinetics | Acute myeloid leukemia | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 08/2003, Volume 9, Issue 9, pp. 3246 - 3253
Purpose: The purpose was to explore the relationships between irinotecan disposition and allelic variants of genes coding for adenosine triphosphate binding... 
P-Glycoprotein/genetics | Multidrug Resistance-Associated Proteins/genetics | Cytochrome P-450 Enzyme System/genetics | Humans | Male | Carboxylesterase/genetics | Glucuronic Acids/chemistry | Middle aged | Neoplasm Proteins/genetics | Adult | Female | Gene Frequency | Genotype | Membrane Transport Proteins/genetics | Polymorphism, Genetic | Homozygote | Phenotype | DNA-Binding Proteins/genetics | Models, Biological | Alleles | Adenosine Triphosphate/genetics | Cell Line, Tumor | Protein Binding | ATP-Binding Cassette Transporters/genetics | Camptothecin/analogs & derivatives/pharmacokinetics/pharmacology | Aged | Research Support, U.S. Gov't, P.H.S | Glucuronosyltransferase/genetics | GILBERTS-SYNDROME | 7-ETHYL-10-HYDROXYCAMPTOTHECIN SN-38 | CANCER-PATIENTS | UDP-GLUCURONOSYLTRANSFERASE GENE | CPT-11 | METABOLISM | ONCOLOGY | IN-VIVO | RESISTANCE | PHARMACOGENETICS | CLINICAL PHARMACOKINETICS | Cytochrome P-450 CYP3A | Middle Aged | Adenosine Triphosphate - genetics | Glucuronosyltransferase - genetics | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | Multidrug Resistance-Associated Proteins - genetics | Glucuronates - chemistry | Neoplasm Proteins - genetics | Camptothecin - analogs & derivatives | Camptothecin - pharmacokinetics | ATP Binding Cassette Transporter, Subfamily G, Member 2 | DNA-Binding Proteins - genetics | ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics | Irinotecan | Carboxylesterase - genetics | Cytochrome P-450 Enzyme System - genetics | X-ray Repair Cross Complementing Protein 1 | Camptothecin - pharmacology | Research Support; U.S. Gov't; P.H.S | Medical and Health Sciences | Medicin och hälsovetenskap | MEDICINE | Polymorphism; Genetic | Models; Biological | MEDICIN | Cell Line; Tumor
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 04/2008, Volume 48, Issue 4, pp. 475 - 484
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 02/2020, Volume 60, Issue 2, pp. 218 - 228
Journal Article
European Journal of Clinical Pharmacology, ISSN 0031-6970, 3/2013, Volume 69, Issue 3, pp. 477 - 487
Interactions between ticagrelor and atorvastatin or simvastatin were investigated in two-way crossover studies.Both studies were open-label for statin; the... 
Co-administration | AZD6140 | Biomedicine | Simvastatin | Atorvastatin | Pharmacology/Toxicology | Ticagrelor | Pharmacokinetics | COA REDUCTASE INHIBITORS | SLCO1B1 POLYMORPHISM | ACUTE CORONARY SYNDROMES | CLINICAL PHARMACOKINETICS | STATINS | RECEPTOR ANTAGONIST | SERUM CONCENTRATIONS | TASK-FORCE | PHARMACOLOGY & PHARMACY | P2Y RECEPTOR | Hydroxymethylglutaryl-CoA Reductase Inhibitors - administration & dosage | Adenosine - pharmacokinetics | Purinergic P2Y Receptor Antagonists - administration & dosage | Pyrroles - pharmacokinetics | Simvastatin - adverse effects | Area Under Curve | Heptanoic Acids - pharmacokinetics | Humans | Hydroxymethylglutaryl-CoA Reductase Inhibitors - blood | Half-Life | Male | Metabolic Clearance Rate | Heptanoic Acids - adverse effects | Simvastatin - blood | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Purinergic P2Y Receptor Antagonists - adverse effects | Drug Interactions | Pyrroles - administration & dosage | Adenosine - adverse effects | Biotransformation | Platelet Aggregation Inhibitors - administration & dosage | Heptanoic Acids - administration & dosage | Pyrroles - adverse effects | Adult | Female | Platelet Aggregation Inhibitors - pharmacokinetics | Drug Therapy, Combination | Platelet Aggregation Inhibitors - adverse effects | Drug Administration Schedule | Simvastatin - administration & dosage | Purinergic P2Y Receptor Antagonists - pharmacokinetics | Linear Models | Pyrroles - blood | Simvastatin - pharmacokinetics | Adenosine - administration & dosage | Cross-Over Studies | Atorvastatin Calcium | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Adenosine - analogs & derivatives | Least-Squares Analysis | Heptanoic Acids - blood | Dosage and administration | Metabolites | Drug interactions | Antilipemic agents | Drug therapy | Pharmacology | Kinetics
Journal Article