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American Journal of Physiology - Endocrinology and Metabolism, ISSN 0193-1849, 11/2016, Volume 311, Issue 5, pp. E859 - E868
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 01/2010, Volume 30, Issue 2, pp. 545 - 555
Marijuana is a widely used drug that impairs memory through interaction between its psychoactive constituent, Delta-9-tetrahydrocannabinol (Delta(9)-THC), and... 
CA1 Region, Hippocampal - cytology | Receptor, Adenosine A1 - physiology | Neurons - cytology | Xanthines - pharmacology | Excitatory Postsynaptic Potentials - drug effects | Patch-Clamp Techniques - methods | Receptor, Cannabinoid, CB1 - physiology | Excitatory Postsynaptic Potentials - physiology | Quinoxalines - pharmacology | Neural Inhibition - physiology | Receptor, Cannabinoid, CB1 - agonists | Piperidines - pharmacology | Caffeine - pharmacology | Dronabinol - pharmacology | Electric Stimulation - methods | Pyrazoles - pharmacology | Presynaptic Terminals - drug effects | Mice, Inbred C57BL | Morpholines - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Biophysics | Calcium Channel Blockers - pharmacology | GABA Antagonists - pharmacology | Mice, Knockout | Naphthalenes - pharmacology | Methoxyhydroxyphenylglycol - analogs & derivatives | Methoxyhydroxyphenylglycol - pharmacology | Animals | Analysis of Variance | Phosphinic Acids - pharmacology | Benzoxazines - pharmacology | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Adenosine - metabolism | Picrotoxin - pharmacology | Presynaptic Terminals - metabolism | Glutamic Acid - metabolism | Mice | Receptor, Cannabinoid, CB1 - deficiency | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | In Vitro Techniques | Propanolamines - pharmacology | Neural Inhibition - drug effects
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 01/2013, Volume 304, Issue 1, pp. R23 - R32
The interaction between adenosine and soluble epoxide hydrolase (sEH) in vascular response is not known. Therefore, we hypothesized that lack of sEH in mice... 
Relaxation | CYP2J5-epoxgenase;ω-hydroxylase | receptor | Soluble epoxide hydrolase | Contraction | Adenosine A | Epoxide Hydrolases - physiology | Adenosine-5'-(N-ethylcarboxamide) - pharmacology | Butyrates - pharmacology | Male | Receptor, Adenosine A2A - physiology | Lauric Acids - pharmacology | Vasodilation - genetics | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Adenosine A2 Receptor Agonists - pharmacology | Urea - analogs & derivatives | Female | Benzamides - pharmacology | Oxygenases - physiology | Vasodilation - physiology | 8,11,14-Eicosatrienoic Acid - pharmacology | Adamantane - analogs & derivatives | NG-Nitroarginine Methyl Ester - pharmacology | Adamantane - pharmacology | Triazines - pharmacology | Phenethylamines - pharmacology | Vasodilator Agents - pharmacology | Enzyme Inhibitors - pharmacology | Gene Silencing | Adenosine - pharmacology | Pyrimidines - pharmacology | Epoxide Hydrolases - genetics | Triazoles - pharmacology | Adenosine A2 Receptor Antagonists - pharmacology | PPAR gamma - physiology | Animals | Adenosine - analogs & derivatives | Benzoates - pharmacology | Mice | Phenylurea Compounds - pharmacology | Pyridines - pharmacology | Vasodilation - drug effects | Urea - pharmacology | adenosine A2a receptor | CYP2J5-epoxgenase | ω-hydroxylase | relaxation | contraction | Cardiovascular and Renal Integration | soluble epoxide hydrolase | adenosine A1 receptor
Journal Article
Current Medicinal Chemistry, ISSN 0929-8673, 01/2012, Volume 19, Issue 2, pp. 239 - 280
Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole ring are readily able to bind with a variety of enzymes and receptors in... 
Triazole | Antifungal | Antidiabetic | Triazolium | Anticonvulsant | Antibacterial | Antihistaminic | Antitubercular | Analgesic | Anti-obesitic | Antiparasitic | Antiviral | Anticancer | Anti-inflammatory | Anti-neuropathic | A ADENOSINE RECEPTOR | analgesic | antibacterial | anticancer | triazole | CLICK CHEMISTRY APPROACH | antihistaminic | ANTIBACTERIAL ACTIVITY | anti-inflammatory | BIOLOGICAL EVALUATION | PHARMACOLOGY & PHARMACY | anti-neuropathic | CHEMISTRY, MEDICINAL | INOSINE MONOPHOSPHATE DEHYDROGENASE | anticonvulsant | BIOCHEMISTRY & MOLECULAR BIOLOGY | EFFICIENT SYNTHESIS | PHARMACOLOGICAL IN-VITRO | AZOLE ANTIFUNGAL AGENTS | antitubercular | anti-obesitic | triazolium | antiviral | antiparasitic | antidiabetic | HISTONE DEACETYLASE INHIBITORS | ANTIMICROBIAL ACTIVITY | Antifungal Agents - pharmacology | Analgesics - pharmacology | Antiviral Agents - pharmacology | Antitubercular Agents - chemistry | Anti-Inflammatory Agents - pharmacology | Triazoles - chemistry | Antitubercular Agents - pharmacology | Antifungal Agents - chemistry | Hypoglycemic Agents - chemistry | Antineoplastic Agents - chemistry | Anticonvulsants - pharmacology | Hypoglycemic Agents - pharmacology | Triazoles - pharmacology | Anti-Inflammatory Agents - chemistry | Analgesics - chemistry | Antiviral Agents - chemistry | Anti-Bacterial Agents - chemistry | Anticonvulsants - chemistry | Antiparasitic Agents - pharmacology | Anti-Bacterial Agents - pharmacology | Antineoplastic Agents - pharmacology | Antiparasitic Agents - chemistry
Journal Article
The Journal of physiology, ISSN 0022-3751, 2010, Volume 588, Issue 14, pp. 2605 - 2619
In vertebrate retina, melatonin regulates various physiological functions. In this work we investigated the mechanisms underlying melatonin‐induced... 
CIRCADIAN CLOCK | PROTEIN-KINASE-C | ACTIVATION | PHYSIOLOGY | PHOSPHOLIPASE-C | VISUAL PATHWAY | FUNCTIONAL-ROLE | RECEPTOR | MT2 MELATONIN | EXPRESSION | NEUROSCIENCES | MODULATION | Cyclic GMP - pharmacology | Receptor, Melatonin, MT2 - antagonists & inhibitors | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Male | Calcium - analysis | Melatonin - physiology | Type C Phospholipases - antagonists & inhibitors | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclic GMP-Dependent Protein Kinases - physiology | Isoquinolines - pharmacology | Cyclic GMP - analogs & derivatives | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Bridged-Ring Compounds - pharmacology | Egtazic Acid - analogs & derivatives | Indoles - pharmacology | Guanosine Diphosphate - pharmacology | Pertussis Toxin - pharmacology | Retinal Ganglion Cells - physiology | Protein Kinase C - physiology | Retinal Ganglion Cells - enzymology | 8-Bromo Cyclic Adenosine Monophosphate - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Receptor, Melatonin, MT2 - physiology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Animals | Egtazic Acid - pharmacology | Glycine - physiology | Guanosine Diphosphate - analogs & derivatives | Signal Transduction - drug effects | Tetrahydronaphthalenes - pharmacology | Thiones - pharmacology | Carbazoles - pharmacology | Type C Phospholipases - physiology | Melatonin | Phospholipids | Glycine | Ganglion | Gross domestic product | Protein kinases | Kinases | Retina | Physiology | Neuroscience
Journal Article
Journal of neurochemistry, ISSN 0022-3042, 2011, Volume 118, Issue 5, pp. 826 - 840
J. Neurochem. (2011) 118, 826–840. Inflammation contributes to neurodegeneration in post‐ischemic brain, diabetes, and Alzheimer’s disease. Participants in... 
gap junctions | Alzheimer’s disease | amyloid β‐peptide | cytokines | diabetes mellitus | pannexin | stroke | connexin | amyloid β-peptide | Alzheimer's disease | BRAIN-INJURY | GAP JUNCTIONAL COMMUNICATION | ALZHEIMERS-DISEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMYLOID PLAQUES | ASTROCYTES | NEUROTOXICITY | NEUROSCIENCES | BETA | IN-VIVO | CHANNELS | RECEPTORS | amyloid beta-peptide | Tumor Necrosis Factor-alpha - metabolism | Oxygen - pharmacology | Cell Hypoxia - physiology | Amyloid beta-Peptides - pharmacology | Microtubule-Associated Proteins - pharmacology | Culture Media, Conditioned - pharmacology | Lanthanum - pharmacology | Peptide Fragments - pharmacology | Cerebral Cortex - cytology | Adenosine Triphosphate - pharmacology | Time Factors | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Neuropeptides - pharmacology | Nerve Tissue Proteins - pharmacology | Neurons - physiology | Astrocytes - chemistry | Female | Cell Death - drug effects | Connexins - pharmacology | Neurons - drug effects | Animals, Newborn | Astrocytes - drug effects | Cell Hypoxia - drug effects | Connexin 43 - metabolism | Glutamic Acid - pharmacology | Cells, Cultured | Fluoresceins | Coculture Techniques - methods | Connexin 43 - deficiency | Connexins - metabolism | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Biotinylation - methods | Glutamic Acid - metabolism | Mice | Astrocytes - metabolism | Methyl aspartate | Neurosciences | Peptides | Neurons | Diabetes | Glucose | Glutamate | Dextrose | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 09/2012, Volume 32, Issue 38, pp. 13100 - 13110
Astrocytes contribute to many neuronal functions, including synaptogenesis, but their role in the development of synaptic plasticity remains unclear.... 
NEUROPATHIC PAIN | PYRAMIDAL CELLS | PROTEIN-KINASE | NECROSIS-FACTOR-ALPHA | SILENT SYNAPSES | ANTIEPILEPTIC DRUGS | GABAPENTIN | DIFFERENTIAL REGULATION | NEUROSCIENCES | CALCIUM-CHANNEL | GLIAL TNF-ALPHA | Electric Stimulation | Coculture Techniques | Culture Media, Conditioned - chemistry | Neuronal Plasticity - drug effects | Culture Media, Conditioned - pharmacology | Male | Excitatory Postsynaptic Potentials - drug effects | N-Methylaspartate - pharmacology | Thrombospondins - pharmacology | Quinoxalines - pharmacology | CREB-Binding Protein - metabolism | Cyclic AMP - analogs & derivatives | Potassium Chloride - pharmacology | Statistics, Nonparametric | Female | Phosphorylation - drug effects | Hippocampus - growth & development | Organ Culture Techniques | Receptors, AMPA - metabolism | Animals, Newborn | Synapses - drug effects | Presynaptic Terminals - drug effects | Vesicular Glutamate Transport Protein 1 - metabolism | Valine - analogs & derivatives | Rats | gamma-Aminobutyric Acid - pharmacology | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Adenosine - pharmacology | Biophysics | Thionucleotides - pharmacology | Hippocampus - cytology | Rats, Sprague-Dawley | Cyclic AMP - pharmacology | Nerve Tissue Proteins - metabolism | Astrocytes - physiology | Patch-Clamp Techniques | Animals | Cyclohexanecarboxylic Acids - pharmacology | Adenosine - analogs & derivatives | Dynamin I - metabolism | Protein Kinase Inhibitors - pharmacology | Valine - pharmacology | Amines - pharmacology | Thrombospondins - metabolism
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2006, Volume 26, Issue 11, pp. 2862 - 2870
Neuronal activity evokes localized changes in blood flow. Although this response, termed neurovascular coupling, is widely used to monitor human brain function... 
Arachidonic acid metabolites | Retina | Calcium | Glia | ATP | Blood flow | arachidonic acid metabolites | 20-HETE | calcium | RAT | ASTROCYTE-MEDIATED CONTROL | CALCIUM WAVES | EPOXYGENASE | ARACHIDONIC-ACID | RELEASE | glia | NEUROSCIENCES | HEMODYNAMIC-RESPONSE | retina | NITRIC-OXIDE | blood flow | BRAIN | Arterioles - physiology | Cytochrome P-450 Enzyme Inhibitors | Rats, Long-Evans | Arterioles - enzymology | Nitric Oxide Synthase - physiology | Male | Vasodilation - radiation effects | Retinal Vessels - enzymology | Retinal Vessels - physiology | Hydroxyeicosatetraenoic Acids - biosynthesis | Vasoconstriction - radiation effects | Photolysis | Cyclic N-Oxides - pharmacology | Inositol 1,4,5-Trisphosphate - analogs & derivatives | Eye Proteins - antagonists & inhibitors | Purinergic Antagonists | Signal Transduction - radiation effects | Cytochrome P-450 Enzyme System - physiology | Hydrazines - pharmacology | Rats | Imidazoles - pharmacology | Retinal Vessels - drug effects | Arterioles - drug effects | Vasoconstriction - drug effects | Cytochrome P-450 CYP4A - physiology | Signal Transduction - drug effects | Miconazole - pharmacology | Eye Proteins - physiology | Retinal Vessels - radiation effects | Vasodilation - drug effects | Arterioles - radiation effects | Nitric Oxide - pharmacology | Caproates - pharmacology | Vasomotor System - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Inositol 1,4,5-Trisphosphate - pharmacology | Adenosine Triphosphate - pharmacology | Vasoconstriction - physiology | 8,11,14-Eicosatrienoic Acid - analogs & derivatives | Proadifen - pharmacology | Nitric Oxide Donors - pharmacology | Vasodilation - physiology | 8,11,14-Eicosatrienoic Acid - pharmacology | NG-Nitroarginine Methyl Ester - pharmacology | Calcium Signaling - radiation effects | Cytochrome P-450 CYP4A - antagonists & inhibitors | Neuroglia - physiology | Nitric Oxide - physiology | Vasomotor System - radiation effects | Animals | Vasomotor System - physiology | Amidines - pharmacology | In Vitro Techniques
Journal Article
Nature neuroscience, ISSN 1546-1726, 2011, Volume 14, Issue 7, pp. 881 - 888
Striatal spiny neurons (SPNs) associate a diverse array of cortically processed information to regulate action selection. But how this is done by SPNs is... 
CALCIUM-CHANNELS | BASAL GANGLIA | IN-VIVO | RECEPTOR ACTIVATION | INTRACELLULAR-RECORDINGS | PROJECTION NEURONS | LONG-TERM POTENTIATION | NEOSTRIATAL NEURONS | NEUROSCIENCES | DOPAMINERGIC CONTROL | CA1 PYRAMIDAL NEURONS | Electric Stimulation | Calcium - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Neurons - cytology | Green Fluorescent Proteins - genetics | Spider Venoms - pharmacology | Corpus Striatum - cytology | Excitatory Postsynaptic Potentials - drug effects | Nerve Net - physiology | Anesthetics, Local - pharmacology | N-Methylaspartate - pharmacology | Excitatory Postsynaptic Potentials - physiology | Neurons - ultrastructure | Adenosine A2 Receptor Agonists - pharmacology | Time Factors | Dopamine Agents - pharmacology | Dendrites - physiology | Tetrodotoxin - pharmacology | Nickel - pharmacology | Animals, Newborn | Dendrites - drug effects | Mibefradil - pharmacology | Phenethylamines - pharmacology | Synapses - physiology | Mice, Transgenic | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Adenosine - pharmacology | Biophysics | Membrane Potentials - physiology | Calcium Channel Blockers | Microscopy, Confocal | Patch-Clamp Techniques | Animals | Adenosine - analogs & derivatives | Mice | Models, Neurological | In Vitro Techniques | Physiological aspects | Neural receptors | Dendrites | Research | Glutamate
Journal Article
Circulation Research, ISSN 0009-7330, 10/2004, Volume 95, Issue 7, pp. 726 - 733
Altered gap junction coupling of cardiac myocytes during ischemia may contribute to development of lethal arrhythmias. The phosphoprotein connexin 43 (Cx43) is... 
Ischemia | Gap junctions | Glycolysis | Okadaic acid | Protein phosphatases | Connexin43 | Protein phosphorylation | AMP kinase | gap junctions | PROTEIN-KINASE-C | CARDIAC & CARDIOVASCULAR SYSTEMS | connexin43 | PHOSPHORYLATION | GAP JUNCTIONAL COMMUNICATION | glycolysis | ACTIN GENE | protein phosphorylation | okadaic acid | ischemia | INTERCELLULAR COMMUNICATION | IN-VIVO | CONDUCTION | PERIPHERAL VASCULAR DISEASE | JUN KINASE | protein phosphatases | HEMATOLOGY | EXPRESSION | ADRENERGIC REGULATION | Okadaic Acid - pharmacology | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Recombinant Fusion Proteins - physiology | Myocardial Contraction - drug effects | Brefeldin A - pharmacology | Phenanthridines - pharmacology | Antimycin A - pharmacology | Aminoimidazole Carboxamide - pharmacology | Cell Hypoxia | Ribonucleotides - pharmacology | Alkaloids | Protein Processing, Post-Translational - drug effects | Adenosine Triphosphate - metabolism | Deoxyglucose - pharmacology | Tacrolimus - pharmacology | Indoles - pharmacology | Flavonoids - pharmacology | Potassium Cyanide - pharmacology | JNK Mitogen-Activated Protein Kinases - genetics | Phosphorylation - drug effects | Ouabain - pharmacology | Cells, Cultured - drug effects | Connexin 43 - metabolism | Rats | Imidazoles - pharmacology | Cycloheximide - pharmacology | Pyrroles - pharmacology | Animals | Myocytes, Cardiac - drug effects | Aminoimidazole Carboxamide - analogs & derivatives | Benzophenanthridines | JNK Mitogen-Activated Protein Kinases - physiology | Myocytes, Cardiac - metabolism | Cells, Cultured - metabolism | Pyridines - pharmacology | Carbazoles - pharmacology | Staurosporine - pharmacology
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 04/2011, Volume 31, Issue 14, pp. 5235 - 5243
R-type calcium channels in postsynaptic spines signal through functional calcium microdomains to regulate a calcium/calmodulin-sensitive potassium channel that... 
DENDRITIC SPINES | TRANSMITTER RELEASE | MUTANT MICE | I ADENYLYL-CYCLASE | CA2+ CHANNELS | EXCITATORY SYNAPSES | CEREBELLAR SYNAPSE | MAMMALIAN BRAIN SLICE | SYNAPTIC PLASTICITY | NEUROSCIENCES | GRANULE CELL | Neural Pathways - drug effects | Calcium - metabolism | Membrane Microdomains - metabolism | Adenosine A1 Receptor Antagonists - pharmacology | Spider Venoms - pharmacology | Xanthines - pharmacology | Neural Pathways - physiology | Patch-Clamp Techniques - methods | Purkinje Cells - physiology | Dose-Response Relationship, Drug | Quinoxalines - pharmacology | omega-Conotoxin GVIA - pharmacology | Long-Term Potentiation - drug effects | Piperidines - pharmacology | Purkinje Cells - cytology | omega-Agatoxin IVA - pharmacology | Long-Term Potentiation - physiology | Tetrodotoxin - pharmacology | Nickel - pharmacology | Electric Stimulation - methods | Pyrazoles - pharmacology | Animals, Newborn | Presynaptic Terminals - drug effects | Rats | Sodium Channel Blockers - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Calcium Channel Blockers - pharmacology | Rats, Sprague-Dawley | GABA Antagonists - pharmacology | Animals | Analysis of Variance | Calcium Signaling - drug effects | Membrane Microdomains - drug effects | Phosphinic Acids - pharmacology | Cerebellum - cytology | In Vitro Techniques | Propanolamines - pharmacology | Calcium Channels, R-Type - metabolism
Journal Article