X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4523) 4523
Publication (601) 601
Book Review (57) 57
Book Chapter (37) 37
Book / eBook (29) 29
Dissertation (7) 7
Conference Proceeding (5) 5
Newspaper Article (4) 4
Reference (2) 2
Newsletter (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (3206) 3206
humans (1784) 1784
index medicus (1629) 1629
male (1581) 1581
adenosine (1456) 1456
rats (1403) 1403
adenosine - pharmacology (1161) 1161
adenosine - analogs & derivatives (953) 953
mice (767) 767
neurosciences (748) 748
pharmacology & pharmacy (651) 651
female (624) 624
adenosine - metabolism (596) 596
in vitro techniques (531) 531
dose-response relationship, drug (498) 498
cells, cultured (485) 485
physiology (485) 485
rats, sprague-dawley (458) 458
biochemistry & molecular biology (457) 457
receptor, adenosine a2a - metabolism (456) 456
receptors (436) 436
cell biology (433) 433
activation (413) 413
adenosine receptors (400) 400
calcium - metabolism (377) 377
rats, wistar (370) 370
cyclic amp - metabolism (363) 363
adenosine triphosphate - pharmacology (351) 351
signal transduction (349) 349
receptor (335) 335
phenethylamines - pharmacology (329) 329
adenosine triphosphate - metabolism (328) 328
receptors, purinergic p1 - metabolism (306) 306
xanthines - pharmacology (284) 284
inflammation (283) 283
platelet aggregation - drug effects (272) 272
atp (271) 271
physiological aspects (258) 258
purinergic p1 receptor antagonists (257) 257
article (254) 254
hematology (254) 254
time factors (254) 254
blood platelets - metabolism (251) 251
adenosine diphosphate - pharmacology (250) 250
adenosine a2 receptor agonists (249) 249
mice, inbred c57bl (249) 249
disease models, animal (247) 247
adenosine a2 receptor antagonists (244) 244
adenosine a2 receptor agonists - pharmacology (234) 234
inhibition (234) 234
rodents (233) 233
brain (231) 231
cells (231) 231
peripheral vascular disease (230) 230
proteins (229) 229
kinetics (227) 227
adenosine receptor (224) 224
blood platelets - drug effects (224) 224
purinergic p1 receptor agonists (224) 224
theophylline - pharmacology (221) 221
cell line (219) 219
adenosine-5'- (218) 218
research (218) 218
phosphorylation (215) 215
release (215) 215
signal transduction - drug effects (215) 215
expression (211) 211
biomedicine (209) 209
enzyme inhibitors - pharmacology (209) 209
rat (207) 207
receptors, purinergic p1 - physiology (207) 207
adenosine - physiology (205) 205
adenosine a (203) 203
caffeine (200) 200
adult (197) 197
a receptors (196) 196
triazoles - pharmacology (196) 196
adenosine a2 receptor antagonists - pharmacology (195) 195
analysis (194) 194
receptors, purinergic - metabolism (194) 194
research article (192) 192
immunology (182) 182
brain - metabolism (181) 181
mice, knockout (178) 178
platelet aggregation inhibitors - pharmacology (178) 178
neurology (177) 177
cardiac & cardiovascular systems (176) 176
middle aged (176) 176
medicine (170) 170
pharmacology (169) 169
receptor, adenosine a1 - metabolism (169) 169
calcium (168) 168
neurons (168) 168
caffeine - pharmacology (167) 167
rabbits (167) 167
ligands (163) 163
ischemia (161) 161
signal transduction - physiology (161) 161
metabolism (160) 160
receptors, purinergic - drug effects (160) 160
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (20) 20
Chemistry (A D Allen) - Stacks (1) 1
Collection Dvlpm't (Acquisitions) - Closed Orders (1) 1
Earth Sciences (Noranda) - Stacks (1) 1
Online Resources - Online (1) 1
UTL at Downsview - May be requested (1) 1
UofT at Mississauga - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4569) 4569
Japanese (31) 31
French (3) 3
Korean (3) 3
Chinese (2) 2
Russian (2) 2
Polish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Science, ISSN 0036-8075, 7/2012, Volume 337, Issue 6091, pp. 232 - 236
Pharmacological responses of G protein-coupled receptors (GPCRs) can be fine-tuned by allosteric modulators. Structural studies of such effects have been... 
Molecules | Receptors | Sodium | Molecular structure | REPORTS | Lipids | Ligands | Cell membranes | Cholesterols | Water channels | Crystal structure | ANGSTROM CRYSTAL-STRUCTURE | COMPLEX | ANTAGONIST | OPIOID RECEPTOR | MULTIDISCIPLINARY SCIENCES | RHODOPSIN | PROTEIN-COUPLED RECEPTORS | ADENOSINE A(2A) RECEPTOR | ALPHA-2-ADRENERGIC RECEPTORS | MODULATION | MUSCARINIC ACETYLCHOLINE-RECEPTOR | Allosteric Regulation | Humans | Crystallography, X-Ray | Adenosine A2 Receptor Agonists - metabolism | Recombinant Fusion Proteins - metabolism | Cholesterol - chemistry | Adenosine A2 Receptor Antagonists - metabolism | Lipids - chemistry | Lipid Bilayers | Sodium - analysis | HEK293 Cells | Protein Engineering | Water - chemistry | Triazines - metabolism | Protein Structure, Secondary | Models, Molecular | Receptor, Adenosine A2A - metabolism | Recombinant Fusion Proteins - chemistry | Triazoles - metabolism | Hydrogen Bonding | Receptor, Adenosine A2A - chemistry | Protein Conformation | Cytochrome b Group - chemistry | Escherichia coli Proteins - chemistry | Chemistry | G proteins | Chemical properties | Research | Receptor-mediated endocytosis | Proteins | Ions | Adenosine | Pharmacology | Binding | Control | Stabilization | Strategy | Channels | BASIC BIOLOGICAL SCIENCES | STABILIZATION | CLATHRATES | RESOLUTION | ADENOSINE | REGULATIONS | 60 APPLIED LIFE SCIENCES | RESIDUES | SODIUM IONS | LIPIDS | WATER
Journal Article
Purinergic Signalling, ISSN 1573-9538, 9/2015, Volume 11, Issue 3, pp. 389 - 407
Adenosine receptors (ARs) have emerged as new drug targets. The majority of data on affinity/potency and selectivity of AR ligands described in the literature... 
Neurosciences | Agonist | Biomedicine | Human Physiology | Cancer Research | Selectivity | Potency | Antagonist | Pharmacology/Toxicology | Species differences | Biomedicine general | XANTHINE DERIVATIVES | NEUROSCIENCES | STRIATAL MEMBRANES | PROTEIN-COUPLED ADENOSINE | P2Y RECEPTORS | A(2B) RECEPTORS | INTERNATIONAL UNION | LIGANDS | A(2A) RECEPTOR | HIGHLY POTENT | PARKINSONS-DISEASE | Cricetulus | Species Specificity | Humans | DNA, Complementary - genetics | Adenosine A1 Receptor Antagonists - pharmacology | Adenosine A2 Receptor Agonists - metabolism | Receptor, Adenosine A2B - genetics | Structure-Activity Relationship | Adenosine A1 Receptor Antagonists - metabolism | Adenosine A2 Receptor Antagonists - metabolism | Adenosine A2 Receptor Agonists - pharmacology | Adenosine A3 Receptor Agonists - pharmacology | Adenosine A1 Receptor Agonists - pharmacology | Receptor, Adenosine A2B - drug effects | Receptor, Adenosine A2A - genetics | Adenosine A3 Receptor Antagonists - pharmacology | Cell Membrane - metabolism | Adenosine A3 Receptor Agonists - metabolism | Cyclic AMP - metabolism | Arrestin - metabolism | Cell Membrane - drug effects | DNA, Complementary - drug effects | CHO Cells | Cricetinae | Receptors, Purinergic P1 - genetics | Rats | Receptor, Adenosine A2A - metabolism | Receptor, Adenosine A2B - metabolism | Receptor, Adenosine A2A - drug effects | Binding, Competitive - drug effects | Adenosine A2 Receptor Antagonists - pharmacology | Animals | Adenosine A1 Receptor Agonists - metabolism | Adenosine A3 Receptor Antagonists - metabolism | Mice | Receptors, Purinergic P1 - metabolism | Receptors, Purinergic P1 - drug effects | Adenosine | Original
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2014, Volume 9, Issue 10, pp. e108492 - e108492
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 10/2016, Volume 117, pp. 46 - 56
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 09/2014, Volume 229, Issue 9, pp. 1292 - 1300
The plasma level of the regulatory metabolite adenosine increases during the activation of coagulation and inflammation. Here we investigated the effect of... 
ADHESION | PHYSIOLOGY | ACTIVATED PROTEIN-C | PERMEABILITY | SPECIFICITY | PATHWAY | INFLAMMATION | MECHANISMS | KAPPA-B | RECEPTORS | EXPRESSION | CELL BIOLOGY | Capillary Permeability | Human Umbilical Vein Endothelial Cells - metabolism | Coculture Techniques | Humans | Human Umbilical Vein Endothelial Cells - immunology | NF-kappa B - metabolism | rhoA GTP-Binding Protein - metabolism | Adenosine A2 Receptor Agonists - metabolism | Inflammation - blood | Dose-Response Relationship, Drug | Inflammation - metabolism | Thrombin - pharmacology | Transfection | Adenosine A2 Receptor Agonists - pharmacology | RNA Interference | Inflammation Mediators - metabolism | Receptor, Adenosine A2A - genetics | Cyclic AMP - metabolism | Human Umbilical Vein Endothelial Cells - drug effects | Cells, Cultured | E-Selectin - metabolism | Inflammation - immunology | Adenosine - pharmacology | Receptor, Adenosine A2A - metabolism | Cell Adhesion | Receptor, Adenosine A2B - metabolism | Protein Transport | Adenosine A2 Receptor Antagonists - pharmacology | Intercellular Adhesion Molecule-1 - metabolism | Blood Coagulation - drug effects | Signal Transduction - drug effects | Adenosine - metabolism | Enzyme Activation | Thrombin - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Thrombin | Adenosine | Analysis | Endothelium | Adenosine receptor | Permeability
Journal Article
PLoS Computational Biology, ISSN 1553-734X, 2015, Volume 11, Issue 2, p. e1004044
Journal Article