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Thrombosis and Haemostasis, ISSN 0340-6245, 03/2014, Volume 111, Issue 3, pp. 491 - 507
Journal Article
Molecular medicine reports, ISSN 1791-2997, 09/2015, Volume 12, Issue 3, pp. 4566 - 4571
Purine compounds are known to activate 5'-adenosine monophosphate-activated protein kinase (AMPK... 
5'-adenosine monophosphate-activated protein kinase | ENERGI-F706 | B-cell lymphoma-2-associated X | Caspase | Renal cell carcinoma 786-O | B-cell lymphoma 2 | Apoptosis | Oncology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Plant Extracts - chemistry | AMP-Activated Protein Kinases - metabolism | Caspase 9 - genetics | Caspase 9 - metabolism | Kidney - pathology | Apoptosis - drug effects | Epithelial Cells - drug effects | Humans | Kidney - enzymology | Caspase 3 - metabolism | Gene Expression Regulation, Neoplastic | Purines - isolation & purification | Tumor Suppressor Protein p53 - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Caspase 3 - genetics | bcl-2-Associated X Protein - genetics | Pyrazoles - pharmacology | Cell Line | Kidney - drug effects | Signal Transduction | Purines - pharmacology | Bambusa - chemistry | Tumor Suppressor Protein p53 - metabolism | bcl-2-Associated X Protein - metabolism | Epithelial Cells - pathology | Pyrimidines - pharmacology | Enzyme Activation - drug effects | Organ Specificity | Poly(ADP-ribose) Polymerases - metabolism | Poly(ADP-ribose) Polymerases - genetics | Epithelial Cells - enzymology | Cell Line, Tumor | Antineoplastic Agents, Phytogenic - pharmacology | S Phase Cell Cycle Checkpoints - drug effects | Proto-Oncogene Proteins c-bcl-2 - genetics | AMP-Activated Protein Kinases - genetics | Antineoplastic Agents, Phytogenic - isolation & purification
Journal Article
Life sciences (1973), ISSN 0024-3205, 05/2020, Volume 248, pp. 117477 - 6
A newly emerged Human Coronavirus (HCoV) is reported two months ago in Wuhan, China (COVID-19). Until today >2700 deaths from the 80,000 confirmed cases... 
COVID-19 | Structural bioinformatics | Wuhan coronavirus | Nucleotide inhibitors | RdRp | Docking | Sofosbuvir | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Guanosine Monophosphate - chemistry | Uridine Triphosphate - metabolism | Coronavirus Infections - drug therapy | Humans | Pneumonia, Viral - drug therapy | RNA Replicase - metabolism | Adenosine Monophosphate - chemistry | Betacoronavirus - enzymology | Sofosbuvir - metabolism | Alanine - chemistry | Alphacoronavirus - enzymology | RNA Replicase - antagonists & inhibitors | Guanosine Triphosphate - metabolism | Antiviral Agents - metabolism | Viral Proteins - metabolism | Alanine - analogs & derivatives | Thermodynamics | Alphacoronavirus - genetics | Antiviral Agents - chemistry | Guanosine Monophosphate - analogs & derivatives | Guanosine Triphosphate - chemistry | Protein Interaction Domains and Motifs | Amino Acid Sequence | Protein Conformation, alpha-Helical | Catalytic Domain | Computational Biology - methods | Adenosine Monophosphate - metabolism | Viral Proteins - chemistry | Alanine - metabolism | Viral Proteins - antagonists & inhibitors | Ribavirin - metabolism | Uridine Triphosphate - chemistry | Ribavirin - chemistry | Sequence Homology, Amino Acid | Sequence Alignment | Coronavirus Infections - virology | Protein Conformation, beta-Strand | Guanosine Monophosphate - metabolism | RNA Replicase - chemistry | Adenosine Monophosphate - analogs & derivatives | Drug Repositioning - methods | Protein Binding | Molecular Docking Simulation | Betacoronavirus - genetics | Pneumonia, Viral - virology | Sofosbuvir - chemistry | Drugs | Disease transmission | Nucleotide sequence | Viral diseases | Fatalities | Coronaviruses | RNA polymerase | Nucleotides | DNA-directed RNA polymerase | Ribavirin | Index Medicus
Journal Article
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 01/2012, Volume 307, Issue 3, pp. 265 - 274
Journal Article
PloS one, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, pp. e63102 - e63102
In this study, we investigated inhibition of the phosphorylation of adenosine 5'-monophosphate-activated protein kinase (AMPK... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Gene Expression Regulation, Enzymologic - drug effects | AMP-Activated Protein Kinases - metabolism | Endocrine Glands - drug effects | Molecular Sequence Data | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Aminoimidazole Carboxamide - pharmacology | Dose-Response Relationship, Drug | Ribonucleotides - pharmacology | Bombyx - metabolism | Time Factors | Isoenzymes - metabolism | Larva - drug effects | Larva - genetics | Phosphorylation - drug effects | Chromones - pharmacology | Insect Hormones - pharmacology | Insect Proteins - metabolism | Eukaryotic Initiation Factors - metabolism | Amino Acid Sequence | Ribosomal Protein S6 Kinases, 70-kDa - metabolism | Isoenzymes - genetics | Larva - metabolism | Morpholines - pharmacology | Bombyx - drug effects | Bombyx - genetics | Endocrine Glands - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Sequence Homology, Amino Acid | Ecdysteroids - biosynthesis | Animals | Aminoimidazole Carboxamide - analogs & derivatives | AMP-Activated Protein Kinases - genetics | Viral antibodies | Adenosine | Antibodies | Amino acids | Research | Gene expression | Protein kinases | Protein binding | TOR protein | Larvae | Phosphorylation | Transcription | Zoology | Glands | Homeostasis | Kinases | Western blotting | Proteins | Lysates | Inhibition | AMP | Extracellular signal-regulated kinase | Rapamycin | Museums | Ribosomal protein S6 | Metabolism | 1-Phosphatidylinositol 3-kinase | Ribosomal protein S6 kinase | Signaling | Insects | Protein kinase | Adenosine kinase | Protein synthesis | Initiation factor eIF-4E | Index Medicus
Journal Article
Nature communications, ISSN 2041-1723, 01/2020, Volume 11, Issue 1, pp. 222 - 222
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 05/2020, Volume 368, Issue 6492, pp. 779 - 782
Journal Article