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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 30, pp. 11025 - 11030
ATP binding cassette (ABC) transporters mediate vital transport processes in every living cell. ATP hydrolysis, which fuels transport, displays positive... 
ATP binding cassette transporters | Hydrolysis | Hydrogen bonds | Adenosine triphosphatases | Crystals | Dimers | Nucleotides | Exporters | Binding sites | Crystal structure | X-ray crystallography | Membrane transport | Allosteric communication | allosteric communication | DOMAIN | TRANSPORTER MSBA | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | HYDROLYSIS | ATP-BINDING | P-GLYCOPROTEIN | DIMER | membrane transport | CASSETTE TRANSPORTER | CHLORIDE CHANNEL | MOLECULAR-BASIS | Lactococcus lactis - genetics | Protein Structure, Tertiary | Adenosine Monophosphate - genetics | Protein Structure, Secondary | Adenosine Monophosphate - metabolism | Lactococcus lactis - chemistry | Adenosine Monophosphate - chemistry | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Adenosine Triphosphate - genetics | Lactococcus lactis - metabolism | ATP-Binding Cassette Transporters - chemistry | ATP-Binding Cassette Transporters - genetics | Allosteric Regulation - physiology | Biological Transport, Active - physiology | Adenosine Monophosphate - analogs & derivatives | Adenosine Triphosphate - metabolism | Allosteric Site | ATP-Binding Cassette Transporters - metabolism | Bacterial Proteins - metabolism | Adenosine Triphosphate - chemistry | Protein research | Research | Properties | Protein binding | Membrane proteins | ABC transporters | Mutation | Molecular structure | Adenosine triphosphatase | Cells | Index Medicus | Biological Sciences
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 2017, Volume 45, Issue 1, pp. 206 - 214
The DEAH-box ATP-dependent RHAU helicases specifically unfold RNA and DNA G-quadruplexes (G4s). However, it remains unclear how the RHAU's G4 unfolding... 
TRANSLOCATION | TETRAMOLECULAR QUADRUPLEX G4-DNA | RNA-BINDING | MECHANISM | RECOGNITION | RESOLVASE 1 | DEAH-BOX HELICASE | MAJOR SOURCE | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | UNWINDS | Adenosine Diphosphate - genetics | Adenosine Monophosphate - genetics | Humans | Adenosine Monophosphate - chemistry | Adenosine Triphosphate - genetics | Adenosine Diphosphate - chemistry | Isoenzymes - chemistry | Single Molecule Imaging | Drosophila Proteins - metabolism | RNA - genetics | Drosophila melanogaster - metabolism | Thermodynamics | Isoenzymes - metabolism | Adenosine Triphosphate - metabolism | Cloning, Molecular | Escherichia coli - metabolism | Protein Domains | G-Quadruplexes | Optical Tweezers | DEAD-box RNA Helicases - metabolism | DEAD-box RNA Helicases - chemistry | RNA - metabolism | Recombinant Proteins - metabolism | Gene Expression | Adenosine Monophosphate - metabolism | Isoenzymes - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | DNA - metabolism | Drosophila Proteins - chemistry | RNA - chemistry | DNA - genetics | Hydrolysis | DEAD-box RNA Helicases - genetics | DNA - chemistry | Animals | Drosophila melanogaster - chemistry | Escherichia coli - genetics | Protein Binding | Adenosine Diphosphate - metabolism | Drosophila Proteins - genetics | Kinetics | Magnetic Fields | Adenosine Triphosphate - chemistry | Index Medicus | Genome Integrity, Repair and
Journal Article
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2016, Volume 291, Issue 35, pp. 18072 - 18083
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2013, Volume 110, Issue 13, pp. 5109 - 5114
Toll-like receptors (TLRs) are the central players in innate immunity. In particular, TLR9 initiates inflammatory response by recognizing DNA, imported by... 
Heart | Neurons | DNA | Toll like receptors | Myocardium | Antigen presenting cells | Cellular immunity | Macrophages | Cellular differentiation | Endosomes | SYSTEM | ACTIVATED PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | CARDIAC-HYPERTROPHY | TOLL-LIKE RECEPTORS | INJURY | ISCHEMIA | CASCADE | STRESS | BACTERIAL-DNA | BRAIN | AMP-Activated Protein Kinases - metabolism | Adenosine Monophosphate - genetics | Rats, Wistar | Toll-Like Receptor 9 - genetics | Adenosine Triphosphate - genetics | Neurons - cytology | Protein Transport - physiology | Inflammation - metabolism | Membrane Transport Proteins - genetics | Adenosine Triphosphate - metabolism | Muscle Proteins - metabolism | Membrane Transport Proteins - metabolism | Neurons - metabolism | Energy Metabolism - physiology | Caenorhabditis elegans - metabolism | Myocytes, Cardiac - cytology | Adenosine Monophosphate - metabolism | Caenorhabditis elegans - genetics | Cells, Cultured | Rats | Nerve Tissue Proteins - genetics | Mice, Knockout | Muscle Proteins - genetics | Nerve Tissue Proteins - metabolism | Animals | Inflammation - genetics | Myocytes, Cardiac - metabolism | Signal Transduction - physiology | Mice | Toll-Like Receptor 9 - metabolism | AMP-Activated Protein Kinases - genetics | Physiological aspects | Toll-like receptors | Research | Heart cells | Tissue | Cardiomyocytes | T cell receptors | Kinases | Metabolism | Deoxyribonucleic acid--DNA | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2010, Volume 107, Issue 51, pp. 22243 - 22248
Astrocyte-elevated gene-1 (AEG-1) expression increases in multiple cancers and plays a crucial role in oncogenic transformation and angiogenesis, which are... 
Epithelial cells | Astrocytes | Cell lines | HeLa cells | Infections | Metastasis | Oncogenes | Cancer | Tumors | Apoptosis | PATHWAYS | APOPTOSIS | AMPK/mTOR | METASTASIS | TUMOR PROGRESSION | MECHANISM | MULTIDISCIPLINARY SCIENCES | CELL-SURVIVAL | BREAST-CANCER | DEPRIVATION | CHEMORESISTANCE | doxorubicin | CANCER PROGRESSION | LC3 | Neoplasms - metabolism | Adenosine Monophosphate - genetics | Cell Adhesion Molecules - genetics | Microtubule-Associated Proteins - genetics | TOR Serine-Threonine Kinases - metabolism | Adenosine Monophosphate - metabolism | Microtubule-Associated Proteins - metabolism | Humans | Adenosine Triphosphate - genetics | Drug Resistance, Neoplasm | Male | Pyrimidines - pharmacology | Neoplasm Proteins - metabolism | Autophagy | Cell Adhesion Molecules - metabolism | TOR Serine-Threonine Kinases - genetics | Autophagy-Related Protein 5 | Neoplasms - genetics | Adenosine Triphosphate - metabolism | Adenylate Kinase | Neoplasm Proteins - genetics | Cell Line, Transformed | Pyrazoles - pharmacology | Autophagy (Cytology) | Care and treatment | Physiological aspects | Genetic aspects | Dosage and administration | Research | Gene expression | Doxorubicin | Studies | Angiogenesis | Chemotherapy | Oncology | Drug resistance | Kinases | Index Medicus | Transformation | AMP | Tumor cells | Chemoresistance | chemosensitization | Metabolism | Metastases | ATP | Phagocytosis | mTOR | Biological Sciences | AMPK
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2008, Volume 180, Issue 9, pp. 6288 - 6296
After an inflammatory stimulus, lymphocyte migration into draining lymph nodes increases dramatically to facilitate the encounter of naive T cells with... 
ECTO-5'-NUCLEOTIDASE CD73 | IMMUNE-RESPONSE | L-SELECTIN | HUMAN DENDRITIC CELLS | VASCULAR ADHESION | BARRIER FUNCTION | RECEPTOR | DEFICIENT MICE | IMMUNOLOGY | HIGH ENDOTHELIAL VENULES | T-CELLS | Tumor Necrosis Factor-alpha - metabolism | 5'-Nucleotidase - genetics | Adenosine Monophosphate - genetics | T-Lymphocytes - enzymology | Venules - immunology | Dendritic Cells - immunology | Tumor Necrosis Factor-alpha - genetics | Venules - enzymology | Endothelium, Vascular - enzymology | Cell Movement - genetics | Adenosine - genetics | L-Selectin - metabolism | Cell Movement - immunology | L-Selectin - immunology | Receptor, Adenosine A2B - immunology | 5'-Nucleotidase - immunology | Tumor Necrosis Factor-alpha - immunology | Endothelium, Vascular - immunology | Adenosine - immunology | Adenosine Monophosphate - metabolism | Up-Regulation - genetics | Inflammation - immunology | Adenosine Monophosphate - immunology | Lymph Nodes - immunology | Receptor, Adenosine A2B - metabolism | Adenosine A2 Receptor Agonists | Mice, Knockout | Up-Regulation - drug effects | Cell Movement - drug effects | Animals | Up-Regulation - immunology | Dendritic Cells - enzymology | Aminopyridines - pharmacology | Lipopolysaccharides - pharmacology | Adenosine - metabolism | Inflammation - genetics | T-Lymphocytes - immunology | Mice | 5'-Nucleotidase - metabolism | Inflammation - enzymology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN 0363-6119, 2015, Volume 309, Issue 10, pp. R1215 - R1225
AMPK is an endogenous energy sensor that regulates lipid and carbohydrate metabolism. Nonalcoholic fatty liver disease (NAFLD) is regarded as a hepatic... 
Liver kinase B1 | Nonalcoholic fatty liver disease | AMP | AMP-activated protein kinase | Folic acid | METFORMIN | METABOLIC SYNDROME | PHYSIOLOGY | PROTEIN-KINASE | liver kinase B1 | HMG-COA REDUCTASE | LIVER-DISEASE | LKB1