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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2009, Volume 106, Issue 29, pp. 12067 - 12072
...′-triphosphate to trigger antiviral signaling. Hitherto unavailable chemically synthesized 5′-triphosphate RNA ligands do not trigger RIG-I-dependent IFN production in cells... 
Monocytes | Double stranded RNA | RNA | Dendritic cells | Initial value theorem | Anisotropy | Adenosine triphosphatases | Antivirals | Cell lines | Ligands | Interferon production | Virus infection | Retinoid acid-inducible gene-I-like helicases | Melanoma differentiation-associated protein 5 | Immunostimulatory RNA | DOUBLE-STRANDED-RNA | ACID | RECOGNITION | MULTIDISCIPLINARY SCIENCES | immunostimulatory RNA | POLYMERASE | INDUCTION | melanoma differentiation-associated protein 5 | virus infection | RESPONSES | retinoid acid-inducible gene-I-like helicases | HEPATITIS-C VIRUS | INDUCIBLE GENE-I | interferon production | BOX HELICASES | INNATE IMMUNITY | Cell Line | RNA - immunology | Humans | Protein Multimerization | Adenosine Triphosphatases - metabolism | Receptors, Retinoic Acid - metabolism | Viruses - immunology | RNA - chemistry | Viral Proteins - metabolism | Receptors, Pattern Recognition - metabolism | Signal Transduction - immunology | Animals | Base Pairing | Protein Binding | Transcription, Genetic | Mice | DNA-Directed RNA Polymerases - metabolism | Binding Sites | Virus diseases | Genetic aspects | Research | Immunity | Adenosine triphosphatase | Signal transduction | Immunostimulation | Molecular modelling | Transcription | Adenosinetriphosphatase | Defense mechanisms | Genomes | Interferon | Retinoids | Synergism | Cytoplasm | Biological Sciences
Journal Article
Chemistry : a European journal, ISSN 0947-6539, 03/2015, Volume 21, Issue 13, pp. 4988 - 4999
Journal Article
Molecular cell, ISSN 1097-2765, 2008, Volume 29, Issue 2, pp. 169 - 179
The ATPase RIG-I senses viral RNAs that contain 5′-triphosphates in the cytoplasm... 
RNA | MOLIMMUNO | RESPONSES | HELICASE LGP2 | VIRUS | ACID | REPLICATION | RECOGNITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ANTIVIRAL INNATE IMMUNITY | HOST | IDENTIFICATION | ADAPTER PROTEIN | CELL BIOLOGY | RNA Caps - immunology | RNA Helicases - metabolism | Zinc - metabolism | Humans | rab GTP-Binding Proteins - genetics | Structure-Activity Relationship | RNA Helicases - chemistry | Interferons - immunology | RNA Caps - metabolism | Zinc - chemistry | Adenosine Triphosphatases - immunology | Interferon-Induced Helicase, IFIH1 | RNA, Viral - genetics | Immunity, Innate - physiology | RNA Caps - chemistry | Zinc - immunology | RNA Helicases - genetics | RNA, Viral - metabolism | Interferons - genetics | DEAD-box RNA Helicases - metabolism | DEAD-box RNA Helicases - chemistry | Dimerization | RNA Caps - genetics | rab GTP-Binding Proteins - metabolism | Cell Line | DEAD Box Protein 58 | Adenosine Triphosphatases - metabolism | Protein Structure, Tertiary - genetics | Binding Sites - genetics | Substrate Specificity - genetics | Polyphosphates - metabolism | DEAD-box RNA Helicases - genetics | Animals | RNA, Viral - chemistry | Polyphosphates - immunology | rab GTP-Binding Proteins - immunology | DEAD-box RNA Helicases - immunology | Interferons - metabolism | Adenosine Triphosphatases - chemistry | RNA, Viral - immunology | rab GTP-Binding Proteins - chemistry | Adenosine Triphosphatases - genetics | Structural Homology, Protein | RNA Helicases - immunology | Polyphosphates - chemistry | Sensors | G proteins | Biological response modifiers | Adenosine triphosphatase | Index Medicus
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