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1. Full Text The P2X7 receptor antagonist, oxidized adenosine triphosphate, ameliorates renal ischemia-reperfusion injury by expansion of regulatory T cells
by Koo, Tai Yeon and Lee, Jae-Ghi and Yan, Ji-Jing and Jang, Joon Young and Ju, Kyung Don and Han, Miyeun and Oh, Kook-Hwan and Ahn, Curie and Yang, Jaeseok
Kidney international, ISSN 0085-2538, 08/2017, Volume 92, Issue 2, pp. 415 - 431
ischemia-reperfusion injury | regulatory T cells | purinergic receptor | innate immunity | periodate-oxidized adenosine triphosphate | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Kidney - drug effects | Immunity, Innate - drug effects | Kidney - pathology | Reperfusion Injury - pathology | Acute Kidney Injury - pathology | Mice, Inbred C57BL | Male | Purinergic P2X Receptor Antagonists - pharmacology | Acute Kidney Injury - prevention & control | Adenosine Triphosphate - analogs & derivatives | Genes, RAG-1 | Mice, Knockout | Adenosine Triphosphate - pharmacology | Adenosine Triphosphate - therapeutic use | T-Lymphocytes, Regulatory - drug effects | Animals | Reperfusion Injury - prevention & control | Reperfusion Injury - immunology | Fibrosis | Receptors, Purinergic P2X7 - metabolism | Acute Kidney Injury - immunology | Drug Evaluation, Preclinical | Purinergic P2X Receptor Antagonists - therapeutic use | Index Medicus
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2. Full Text New Insights in Purinergic Therapy: Novel Antagonists for Uridine 5′-Triphosphate-Activated P2Y Receptors from Brazilian Flora
by Ferreira, Natiele Carla da Silva and Soares-Bezerra, Rômulo José and da Silveira, Rebeca Ferreira Couto and da Silva, Clayton Menezes and de Oliveira, Carla Santos and Calheiros, Andrea Surrage and Alves, Tânia Maria and Zani, Carlos Leomar and Alves, Luiz Anastacio
Journal of medicinal food, ISSN 1096-620X, 02/2019, Volume 22, Issue 2, pp. 211 - 224
Full Communications | P2Y4 | natural products | screening | calcium | P2Y2 | Food Science & Technology | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Nutrition & Dietetics | Science & Technology | Ionomycin | Calcium - metabolism | Plant Extracts - pharmacology | Plant Leaves | Uridine Triphosphate - pharmacology | Adenosine Triphosphate | Flowers | Magnoliopsida | Macrophages - metabolism | Animals | Receptors, Purinergic P2 - metabolism | Brazil | Inhibitory Concentration 50 | Uridine | Macrophages - drug effects | Mice | Plants - chemistry | Index Medicus | 식품과학
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3. Full Text Adenosine triphosphate-guided pulmonary vein isolation for atrial fibrillation: The UNmasking dormant electrical reconduction by adenosine triphosphate (UNDER-ATP) trial
by Kobori, Atsushi and Shizuta, Satoshi and Inoue, Koichi and Kaitani, Kazuaki and Morimoto, Takeshi and Nakazawa, Yuko and Ozawa, Tomoya and Kurotobi, Toshiya and Morishima, Itsuro and Miura, Fumiharu and Watanabe, Tetsuya and Masuda, Masaharu and Naito, Masaki and Fujimoto, Hajime and Nishida, Taku and Furukawa, Yoshio and Shirayama, Takeshi and Tanaka, Mariko and Okajima, Katsunori and Yao, Takenori and Egami, Yasuyuki and Satomi, Kazuhiro and Noda, Takashi and Miyamoto, Koji and Haruna, Tetsuya and Kawaji, Tetsuma and Yoshizawa, Takashi and Toyota, Toshiaki and Yahata, Mitsuhiko and Nakai, Kentaro and Sugiyama, Hiroaki and Higashi, Yukei and Ito, Makoto and Horie, Minoru and Kusano, Kengo F and Shimizu, Wataru and Kamakura, Shiro and Kimura, Takeshi and UNDER-ATP Trial Investigators
European heart journal, ISSN 0195-668X, 12/2015, Volume 36, Issue 46, pp. 3276 - 3287
Adenosine | Dormant conduction | Atrial fibrillation | Catheter ablation | Pulmonary vein isolation | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Prospective Studies | Humans | Middle Aged | Male | Treatment Outcome | Secondary Prevention | Adenosine Triphosphate | Atrial Fibrillation - surgery | Catheter Ablation - methods | Young Adult | Adult | Female | Pulmonary Veins - surgery | Tachycardia - prevention & control | Index Medicus
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4. Full Text Effects of zidovudine treatment on heart mRNA expression and mitochondrial DNA copy number associated with alterations in deoxynucleoside triphosphate composition in a neonatal rat model
by Snowdin, Jacob W and Hsiung, Chia-Heng and Kesterson, Daniel G and Kamath, Vasudeva G and McKee, Edward E
Antimicrobial agents and chemotherapy, ISSN 0066-4804, 10/2015, Volume 59, Issue 10, pp. 6328 - 6336
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | DNA, Mitochondrial - antagonists & inhibitors | Reverse Transcriptase Inhibitors - toxicity | Anti-HIV Agents - toxicity | Uridine Triphosphate - antagonists & inhibitors | Uridine Triphosphate - biosynthesis | Mitochondrial Proteins - genetics | Cytidine Triphosphate - biosynthesis | Adenosine Triphosphate - biosynthesis | RNA, Messenger - biosynthesis | Adenosine Triphosphate - antagonists & inhibitors | Mitochondrial Proteins - metabolism | RNA, Messenger - antagonists & inhibitors | DNA Copy Number Variations - drug effects | Female | Phosphorylation - drug effects | DNA, Mitochondrial - biosynthesis | Animals, Newborn | Cytidine Triphosphate - antagonists & inhibitors | Guanosine Triphosphate - biosynthesis | Mitochondrial Proteins - antagonists & inhibitors | RNA, Messenger - genetics | Gene Expression Regulation | Rats | Rats, Sprague-Dawley | Pregnancy | Animals | Zidovudine - toxicity | Heart - drug effects | Guanosine Triphosphate - antagonists & inhibitors | Index Medicus | Antiviral Agents
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5. Full Text Polyoxometalates—a new class of potent ecto-nucleoside triphosphate diphosphohydrolase (NTPDase) inhibitors
by Müller, Christa E and Iqbal, Jamshed and Baqi, Younis and Zimmermann, Herbert and Röllich, Anita and Stephan, Holger
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 2006, Volume 16, Issue 23, pp. 5943 - 5947
NTPDases | P2 receptors | Physical Sciences | Chemistry | Chemistry, Organic | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Chemistry, Medicinal | Science & Technology | Biological and medical sciences | General aspects | Miscellaneous | Medical sciences | Antineoplastic agents | Pharmacology. Drug treatments | Apyrase - antagonists & inhibitors | Apyrase - metabolism | Enzyme Inhibitors - pharmacology | Adenosine Triphosphatases - metabolism | Models, Molecular | Rats | Structure-Activity Relationship | Antigens, CD - metabolism | Pyrophosphatases - antagonists & inhibitors | Pyrophosphatases - metabolism | Adenosine Triphosphatases - antagonists & inhibitors | Animals | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - classification | Molecular Structure | Index Medicus
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6. Full Text Mechanosensitive release of adenosine 5′‐triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head astrocytes: A mechanism for purinergic involvement in chronic strain
by Beckel, Jonathan M and Argall, Arthur J and Lim, Jason C and Xia, Jingsheng and Lu, Wennan and Coffey, Erin E and Macarak, Edward J and Shahidullah, Mohammed and Delamere, Nicholas A and Zode, Gulab S and Sheffield, Val C and Shestopalov, Valery I and Laties, Alan M and Mitchell, Claire H
Glia, ISSN 0894-1491, 09/2014, Volume 62, Issue 9, pp. 1486 - 1501
pannexin | P2X7 receptor | glaucoma | cell swelling | ATP release | mechanosensitive signaling | Glaucoma | Mechanosensitive signaling | Pannexin | Cell swelling | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cytoskeletal Proteins - genetics | Rats, Long-Evans | Glycoproteins - metabolism | Stress, Mechanical | Male | Purinergic P2X Receptor Antagonists - pharmacology | Adenosine Triphosphate - metabolism | Cytoskeletal Proteins - metabolism | Female | Eye Proteins - genetics | Optic Disk - physiology | Glaucoma - physiopathology | Osmotic Pressure - physiology | Disease Models, Animal | Glycoproteins - genetics | Astrocytes - drug effects | Mice, Inbred C57BL | Cells, Cultured | Connexins - genetics | Mice, Transgenic | Nerve Tissue Proteins - genetics | Nucleotide Transport Proteins - metabolism | Connexins - metabolism | Mice, Knockout | Nerve Tissue Proteins - metabolism | Astrocytes - physiology | Animals | Eye Proteins - metabolism | Optic Disk - drug effects | Adenosine triphosphatase | Optic nerve | Index Medicus
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7. Full Text Mechanism of Action of T-705 Ribosyl Triphosphate against Influenza Virus RNA Polymerase
by Hidehiro Sangawa and Takashi Komeno and Hiroshi Nishikawa and Atsushi Yoshida and Kazumi Takahashi and Nobuhiko Nomura and Yousuke Furuta
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 11/2013, Volume 57, Issue 11, pp. 5202 - 5208
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Microbiology | Science & Technology | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Antibiotics. Antiinfectious agents. Antiparasitic agents | Amides - pharmacology | Binding, Competitive | Uridine Triphosphate - metabolism | Antiviral Agents - pharmacology | RNA Replicase - genetics | RNA Replicase - metabolism | RNA, Viral - biosynthesis | Cytidine Triphosphate - metabolism | Viral Proteins - genetics | RNA Replicase - antagonists & inhibitors | Viral Proteins - antagonists & inhibitors | Enzyme Assays | Guanosine Triphosphate - metabolism | Influenza A Virus, H1N1 Subtype - drug effects | Viral Proteins - metabolism | RNA, Viral - antagonists & inhibitors | Animals | Adenosine Triphosphate - metabolism | Dogs | Madin Darby Canine Kidney Cells | Protein Binding | Kinetics | Pyrazines - pharmacology | Influenza A Virus, H1N1 Subtype - genetics | Index Medicus | ATP | Antiviral Agents
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8. Full Text Extracellular Adenosine 5'-Triphosphate in Obstructive Airway Diseases
by Pelleg, Amir, PhD and Schulman, Edward S., MD and Barnes, Peter J., DM, Master FCCP
Chest, ISSN 0012-3692, 2016, Volume 150, Issue 4, pp. 908 - 915
Pulmonary/Respiratory | inflammation | ATP | cough | P2 receptors | COPD | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Asthma - metabolism | Signal Transduction | Cough - drug therapy | Humans | Smoking - metabolism | Bronchoconstriction | Extracellular Space - metabolism | Inflammation - metabolism | Cough - metabolism | Adenosine Triphosphate - metabolism | Lung - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Purinergic P2X Receptor Antagonists - therapeutic use | Index Medicus | Abridged Index Medicus
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9. Full Text The purinergic receptor antagonist oxidized adenosine triphosphate suppresses immune-mediated corneal allograft rejection
by Foulsham, William and Mittal, Sharad K and Nakao, Takeshi and Coco, Giulia and YukakoTaketani and Chauhan, Sunil K and Dana, Reza
Scientific reports, ISSN 2045-2322, 06/2019, Volume 9, Issue 1, pp. 8617 - 8
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Flow cytometry | Cornea | Animal models | CD11b antigen | Transplants & implants | Immunoregulation | Purine receptors | Immunomodulation | Effector cells | Lymphocytes T | Transplantation | Leukocytes | CD45 antigen | Graft rejection | CD4 antigen | Antigen-presenting cells | γ-Interferon | Foxp3 protein | ATP | Adenosine triphosphate | Index Medicus
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10. Full Text Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor
by Iwata, Masaaki and Ota, Kristie T and Li, Xiao-Yuan and Sakaue, Fumika and Li, Nanxin and Dutheil, Sophie and Banasr, Mounira and Duric, Vanja and Yamanashi, Takehiko and Kaneko, Koichi and Rasmussen, Kurt and Glasebrook, Andrew and Koester, Anja and Song, Dekun and Jones, Kenneth A and Zorn, Stevin and Smagin, Gennady and Duman, Ronald S
Biological psychiatry (1969), ISSN 0006-3223, 2016, Volume 80, Issue 1, pp. 12 - 22
Psychiatry | Depression | P2X7 | IL-1β | NLRP3 inflammasome | ATP | Stress | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Inflammasomes - metabolism | Male | Stress, Psychological - immunology | Depression - etiology | Purinergic P2Y Receptor Antagonists - metabolism | Depression - metabolism | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Stress, Psychological - metabolism | Receptors, Purinergic P2Y2 - metabolism | Anhedonia - physiology | Anxiety - metabolism | Disease Models, Animal | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Rats | Behavior, Animal - physiology | Rats, Sprague-Dawley | Mice, Knockout | Anxiety - immunology | Animals | Mice | Purinergic P2Y Receptor Agonists - metabolism | Anxiety - etiology | Stress, Psychological - complications | Depression - immunology | Medical colleges | Adenosine | Interleukins | Depression, Mental | Physiological aspects | Muscle proteins | Stress (Psychology) | Adenosine triphosphate | Index Medicus
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