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Journal of Clinical Investigation, ISSN 0021-9738, 08/2018, Volume 128, Issue 8, pp. 3583 - 3594
T cells must migrate in order to encounter antigen-presenting cells (APCs) and to execute their varied functions in immune defense and inflammation. ATP... 
BRONCHIOLITIS | MEDICINE, RESEARCH & EXPERIMENTAL | LUNG-TRANSPLANT | ACTIVATION | CHEMOKINES | CHEMOATTRACTANT | INFLAMMATION | IMMUNE SYNAPSE | DYNAMICS | NEUTROPHIL CHEMOTAXIS | RELEASE | Jurkat Cells | CD4-Positive T-Lymphocytes - cytology | Humans | Receptors, Purinergic P2X4 - immunology | Adenosine Triphosphate - genetics | Adenosine Triphosphate - immunology | Inflammation - immunology | Mitochondria - immunology | Autocrine Communication - genetics | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Animals | Autocrine Communication - immunology | Mitochondria - genetics | Inflammation - genetics | Mice | Mice, Inbred BALB C | Receptors, Purinergic P2X4 - genetics | Mitochondria | Usage | Analysis | Transplantation of organs, tissues, etc | Research | T cells | Adenosine triphosphate | Cell migration | Chemokines | Transplants & implants | Leukocyte migration | Syngeneic grafts | Purine receptors | Lung transplantation | Lymphocytes T | Calcium influx | Inflammatory diseases | Cell adhesion & migration | Cell activation | Lymphocytes | Xenografts | Autocrine signalling | Immune system | Antigens | Lymphatic system | Immunomodulation | Therapeutic applications | Neutrophils | Inflammation | T cell receptors | SDF-1 protein | Calcium (mitochondrial) | CD4 antigen | Graft rejection | Lungs | Antigen-presenting cells
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2013, Volume 8, Issue 5, p. e63759
It has been established that Adenosine-5'-triphosphate (ATP) can activate the NLRP3 inflammasome. However, the physiological effect of extracellular ATP on... 
EXTRACELLULAR ATP | NUCLEOTIDES | IMMUNITY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | RESISTANCE | LUNG INJURY | RECEPTOR | IL-1-BETA | NEUTROPHIL RECRUITMENT | Inflammasomes - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Caspase 1 - metabolism | Male | Caspase 1 - immunology | Bacterial Infections - immunology | Interleukin-1beta - metabolism | Adenosine Triphosphate - metabolism | Chemokine CXCL2 - metabolism | Neutrophils - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Neutrophil Infiltration - immunology | Peritonitis - metabolism | Neutrophils - immunology | Interleukin-1beta - immunology | Adenosine Triphosphate - immunology | Peritonitis - immunology | Bacterial Infections - prevention & control | Chemokine CXCL2 - immunology | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammasomes - immunology | Mice | Bacterial Infections - metabolism | Infection | Medical research | Adenosine | Bacterial infections | Analysis | Physiological aspects | Medicine, Experimental | Hostages | Health aspects | Physiological effects | Laboratories | Zoology | Infections | Activation | Macrophages | Drug resistance | Caspase-1 | Recruitment | Immunology | Enterprise zones | Rodents | Bone marrow | Bacteria | Five year plans | Peritonitis | Immune system | Immune response | Cytokines | Secretion | Neutrophils | Caspase | Leukocytes (neutrophilic) | Injection | IL-1β | Studies | Antibiotics | Sepsis | ATP | Chemokines | Peritoneum
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 06/2009, Volume 30, Issue 6, pp. 860 - 874
Missense mutations of the gene encoding NLRP3 are associated with autoinflammatory disorders characterized with excessive production of interleukin-1β (IL-1β).... 
MOLIMMUNO | CELLIMMUNO | RHEUMATOID-ARTHRITIS | T(H)17 CELLS | TGF-BETA | IL-17-PRODUCING T-CELLS | INTERLEUKIN-1-BETA SECRETION | CASPASE-1 INFLAMMASOME | CYTOKINE MILIEU | IMMUNOLOGY | CIAS1 MUTATIONS | NEUTROPHIL RECRUITMENT | NALP3 INFLAMMASOME | Interleukin-18 - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Skin - metabolism | Mutation - immunology | CD4-Positive T-Lymphocytes - immunology | T-Lymphocytes, Helper-Inducer - immunology | Adenosine Triphosphate - metabolism | Receptors, Antigen, T-Cell - immunology | Interleukin-1beta - biosynthesis | Carrier Proteins - immunology | Macrophages - immunology | Skin - pathology | Cytokines - immunology | Skin - immunology | Antigen-Presenting Cells - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Cytokines - metabolism | Receptors, Antigen, T-Cell - metabolism | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Interleukin-1beta - immunology | Adenosine Triphosphate - immunology | Inflammation - immunology | Mutation - genetics | Antigen-Presenting Cells - immunology | Carrier Proteins - genetics | Cell Differentiation - immunology | Interleukin-18 - biosynthesis | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Inflammation - genetics | Mice | Analysis | Genetic aspects | Immune response | Studies | Bone marrow | Mutation | Gene expression | Immune system
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2011, Volume 286, Issue 30, pp. 26277 - 26286
ATP released from airway epithelial cells promotes purinergic receptor-regulated mucociliary clearance activities necessary for innate lung defense. Cell... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | CELLS | ACTIVATION | MEMBRANE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SURFACE LIQUID VOLUME | SHEAR-STRESS | FIND-ME SIGNAL | CILIARY ACTIVITY | MUCIN SECRETION | TRPV4 CHANNEL | Phosphorylation - physiology | Epithelial Cells - metabolism | Myosin Light Chains - genetics | rhoA GTP-Binding Protein - immunology | Humans | Adenosine Triphosphate - secretion | Connexins - immunology | rhoA GTP-Binding Protein - metabolism | Mutation, Missense | rhoA GTP-Binding Protein - genetics | Lung - cytology | Gene Knockdown Techniques | TRPV Cation Channels - metabolism | Immunity, Innate - physiology | Myosin Light Chains - immunology | Adenosine Triphosphate - metabolism | Respiratory Mucosa - immunology | Lung - metabolism | rho GTP-Binding Proteins - immunology | Epithelial Cells - cytology | Respiratory Mucosa - cytology | Nerve Tissue Proteins - immunology | TRPV Cation Channels - immunology | rho GTP-Binding Proteins - genetics | Cells, Cultured | Connexins - genetics | Adenosine Triphosphate - immunology | Nerve Tissue Proteins - genetics | TRPV Cation Channels - genetics | Connexins - metabolism | Mice, Knockout | Nerve Tissue Proteins - metabolism | Animals | Epithelial Cells - immunology | rho GTP-Binding Proteins - metabolism | Mice | Myosin Light Chains - metabolism | Respiratory Mucosa - metabolism | Lung - immunology | Purinergic Receptor | Signal Transduction | TRP Channels | Epithelial Cell | Rho | ATP Release | ATP | Airway Epithelia | Pannexin 1
Journal Article
Journal Article