Environmental Science & Technology, ISSN 0013-936X, 02/2013, Volume 47, Issue 4, pp. 1870 - 1878
Sunlight inactivation of poliovirus type 3 (PV3), adenovirus type 2 (HAdV2), and two bacteriophage (MS2 and PRD1) was investigated in an array of coastal...
ENVIRONMENTAL SCIENCES | SOLAR DISINFECTION | ENGINEERING, ENVIRONMENTAL | SIMULATED SUNLIGHT | SALINE WATERS | ORGANIC-MATTER | SINGLET OXYGEN | SOUTHERN CALIFORNIA | HUMIC SUBSTANCES | SURFACE WATERS | MS2 COLIPHAGE | MEDIATED INACTIVATION | Oxygen | Adenoviridae - radiation effects | Poliovirus - radiation effects | Bacteriophage PRD1 - radiation effects | Humans | Sunlight | Levivirus - radiation effects | Water Microbiology | Hydrogen-Ion Concentration | Salinity
ENVIRONMENTAL SCIENCES | SOLAR DISINFECTION | ENGINEERING, ENVIRONMENTAL | SIMULATED SUNLIGHT | SALINE WATERS | ORGANIC-MATTER | SINGLET OXYGEN | SOUTHERN CALIFORNIA | HUMIC SUBSTANCES | SURFACE WATERS | MS2 COLIPHAGE | MEDIATED INACTIVATION | Oxygen | Adenoviridae - radiation effects | Poliovirus - radiation effects | Bacteriophage PRD1 - radiation effects | Humans | Sunlight | Levivirus - radiation effects | Water Microbiology | Hydrogen-Ion Concentration | Salinity
Journal Article
Environmental Science & Technology, ISSN 0013-936X, 01/2015, Volume 49, Issue 1, pp. 334 - 342
Sunlight inactivates waterborne viruses via direct (absorption of sunlight by the virus) and indirect processes (adsorption of sunlight by external...
ENVIRONMENTAL SCIENCES | WASTE STABILIZATION PONDS | SUNLIGHT-MEDIATED INACTIVATION | ENGINEERING, ENVIRONMENTAL | RATE CONSTANTS | SINGLET OXYGEN | FECAL INDICATOR MICROORGANISMS | DISSOLVED ORGANIC-MATTER | ULTRAVIOLET LIGHT | SURFACE WATERS | UV/H2O2 ADVANCED OXIDATION | AQUEOUS-SOLUTION | Models, Theoretical | Virus Inactivation - radiation effects | Adenoviridae - radiation effects | Bacteriophage phi X 174 - radiation effects | Disinfection - methods | Sunlight | Levivirus - radiation effects | Kinetics | Water Microbiology
ENVIRONMENTAL SCIENCES | WASTE STABILIZATION PONDS | SUNLIGHT-MEDIATED INACTIVATION | ENGINEERING, ENVIRONMENTAL | RATE CONSTANTS | SINGLET OXYGEN | FECAL INDICATOR MICROORGANISMS | DISSOLVED ORGANIC-MATTER | ULTRAVIOLET LIGHT | SURFACE WATERS | UV/H2O2 ADVANCED OXIDATION | AQUEOUS-SOLUTION | Models, Theoretical | Virus Inactivation - radiation effects | Adenoviridae - radiation effects | Bacteriophage phi X 174 - radiation effects | Disinfection - methods | Sunlight | Levivirus - radiation effects | Kinetics | Water Microbiology
Journal Article
Cancer, ISSN 0008-543X, 01/2012, Volume 118, Issue 2, pp. 536 - 548
BACKGROUND: Although the promoter of the human telomerase reverse transcriptase (hTERT) gene has been widely used in gene therapy for targeted cancer cells, it...
radiotherapy | gene therapy | human telomerase reverse transcriptase gene promoter | CArG elements | horseradish peroxidase | Horseradish peroxidase | Human telomerase reverse transcriptase gene promoter | Gene therapy | Radiotherapy | SYSTEM | HORSERADISH PEROXIDASE/INDOLE-3-ACETIC ACID | CELLS | TELOMERASE | TRANSCRIPTION | COMBINATION | PEROXIDASE | ONCOLOGY | ENHANCEMENT | GROWTH-FACTOR | IONIZING-RADIATION | Promoter Regions, Genetic - radiation effects | Serum Response Element | Humans | Transplantation, Heterologous | Neoplasms - therapy | Animals | Telomerase - genetics | DNA, Recombinant | Telomerase - radiation effects | Adenoviridae - genetics | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Genetic Vectors | Genetic Therapy - methods | Usage | Care and treatment | Promoters (Genetics) | Research | Telomerase | Cancer | Index Medicus | Abridged Index Medicus
radiotherapy | gene therapy | human telomerase reverse transcriptase gene promoter | CArG elements | horseradish peroxidase | Horseradish peroxidase | Human telomerase reverse transcriptase gene promoter | Gene therapy | Radiotherapy | SYSTEM | HORSERADISH PEROXIDASE/INDOLE-3-ACETIC ACID | CELLS | TELOMERASE | TRANSCRIPTION | COMBINATION | PEROXIDASE | ONCOLOGY | ENHANCEMENT | GROWTH-FACTOR | IONIZING-RADIATION | Promoter Regions, Genetic - radiation effects | Serum Response Element | Humans | Transplantation, Heterologous | Neoplasms - therapy | Animals | Telomerase - genetics | DNA, Recombinant | Telomerase - radiation effects | Adenoviridae - genetics | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Genetic Vectors | Genetic Therapy - methods | Usage | Care and treatment | Promoters (Genetics) | Research | Telomerase | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Food and Environmental Virology, ISSN 1867-0334, 12/2014, Volume 6, Issue 4, pp. 260 - 268
Disinfection by low-pressure monochromatic ultraviolet (UVC) radiation (253.7 nm) became an important technique to sanitize drinking water and also wastewater...
MS2 bacteriophage | JC polyomavirus | UV inactivation | Biomedicine | Food Science | Chemistry/Food Science, general | Adenovirus | qPCR | Virology | INDICATOR BACTERIA | QUANTIFICATION | QUANTITATIVE PCR | MICROBIOLOGY | POLYOMAVIRUSES | ENTERIC VIRUSES | ENTEROVIRUSES | ENVIRONMENTAL SCIENCES | HUMAN ADENOVIRUSES | VIROLOGY | BACTERIOPHAGE-MS2 | MOLECULAR-DETECTION | WASTE-WATER | Polyomaviridae - metabolism | Levivirus - pathogenicity | Virion - pathogenicity | Humans | Radiation Tolerance | JC Virus - metabolism | Levivirus - radiation effects | Adenoviridae - pathogenicity | Virus Inactivation - radiation effects | Adenoviridae - radiation effects | Ultraviolet Rays | Adenoviruses, Human - ultrastructure | JC Virus - radiation effects | RNA, Viral - metabolism | Microbial Viability - radiation effects | Levivirus - ultrastructure | Real-Time Polymerase Chain Reaction | Levivirus - metabolism | Virion - radiation effects | Cell Line | Microscopy, Electron, Transmission | RNA, Viral - radiation effects | DNA, Viral - metabolism | JC Virus - ultrastructure | Adenoviruses, Human - pathogenicity | Reverse Transcriptase Polymerase Chain Reaction | Virion - metabolism | Adenoviruses, Human - radiation effects | Polyomaviridae - pathogenicity | Polyomaviridae - ultrastructure | Polyomaviridae - radiation effects | Disinfection - methods | JC Virus - pathogenicity | Virion - ultrastructure | Adenoviridae - ultrastructure | Adenoviridae - metabolism | Kinetics | RNA Stability - radiation effects | Adenoviruses, Human - metabolism | DNA, Viral - radiation effects | Health aspects | Adenoviruses | Analysis | Green technology
MS2 bacteriophage | JC polyomavirus | UV inactivation | Biomedicine | Food Science | Chemistry/Food Science, general | Adenovirus | qPCR | Virology | INDICATOR BACTERIA | QUANTIFICATION | QUANTITATIVE PCR | MICROBIOLOGY | POLYOMAVIRUSES | ENTERIC VIRUSES | ENTEROVIRUSES | ENVIRONMENTAL SCIENCES | HUMAN ADENOVIRUSES | VIROLOGY | BACTERIOPHAGE-MS2 | MOLECULAR-DETECTION | WASTE-WATER | Polyomaviridae - metabolism | Levivirus - pathogenicity | Virion - pathogenicity | Humans | Radiation Tolerance | JC Virus - metabolism | Levivirus - radiation effects | Adenoviridae - pathogenicity | Virus Inactivation - radiation effects | Adenoviridae - radiation effects | Ultraviolet Rays | Adenoviruses, Human - ultrastructure | JC Virus - radiation effects | RNA, Viral - metabolism | Microbial Viability - radiation effects | Levivirus - ultrastructure | Real-Time Polymerase Chain Reaction | Levivirus - metabolism | Virion - radiation effects | Cell Line | Microscopy, Electron, Transmission | RNA, Viral - radiation effects | DNA, Viral - metabolism | JC Virus - ultrastructure | Adenoviruses, Human - pathogenicity | Reverse Transcriptase Polymerase Chain Reaction | Virion - metabolism | Adenoviruses, Human - radiation effects | Polyomaviridae - pathogenicity | Polyomaviridae - ultrastructure | Polyomaviridae - radiation effects | Disinfection - methods | JC Virus - pathogenicity | Virion - ultrastructure | Adenoviridae - ultrastructure | Adenoviridae - metabolism | Kinetics | RNA Stability - radiation effects | Adenoviruses, Human - metabolism | DNA, Viral - radiation effects | Health aspects | Adenoviruses | Analysis | Green technology
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 2016, Volume 82, Issue 1, pp. 279 - 288
Solar disinfection (SODIS) of drinking water in polyethylene terephthalate (PET) bottles is a simple, efficient point-of-use technique for the inactivation of...
INACTIVATION | HUMAN ADENOVIRUSES | SUNLIGHT | SODIS | BACTERIOPHAGE-MS2 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | QUANTITATIVE PCR | MICROBIOLOGY | RADIATION | MS2 COLIPHAGE | WATER | Coliphages - radiation effects | Temperature | Disinfection - statistics & numerical data | Enterovirus B, Human - radiation effects | Humans | Adenoviridae - physiology | Enterovirus B, Human - physiology | Switzerland | DNA Viruses - radiation effects | Coliphages - physiology | India | Drinking Water - virology | Polyethylene Terephthalates | Adenoviridae - radiation effects | Ultraviolet Rays | Viral Load - radiation effects | Disinfection - methods | Sunlight | Virus Inactivation | Water Purification - methods | Bacteriophages | RNA | Analysis | Disinfection and disinfectants | Physiological aspects | Polyethylene terephthalate | Genetic aspects | Research
INACTIVATION | HUMAN ADENOVIRUSES | SUNLIGHT | SODIS | BACTERIOPHAGE-MS2 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ESCHERICHIA-COLI | QUANTITATIVE PCR | MICROBIOLOGY | RADIATION | MS2 COLIPHAGE | WATER | Coliphages - radiation effects | Temperature | Disinfection - statistics & numerical data | Enterovirus B, Human - radiation effects | Humans | Adenoviridae - physiology | Enterovirus B, Human - physiology | Switzerland | DNA Viruses - radiation effects | Coliphages - physiology | India | Drinking Water - virology | Polyethylene Terephthalates | Adenoviridae - radiation effects | Ultraviolet Rays | Viral Load - radiation effects | Disinfection - methods | Sunlight | Virus Inactivation | Water Purification - methods | Bacteriophages | RNA | Analysis | Disinfection and disinfectants | Physiological aspects | Polyethylene terephthalate | Genetic aspects | Research
Journal Article
International Journal of Radiation Biology, ISSN 0955-3002, 02/2017, Volume 93, Issue 2, pp. 174 - 183
Purpose: Gene therapy combined with radiation has shown promising potential for the treatment of tumors. This paper aimed to clarify the synergistic effect of...
gene therapy | oncolytic adenovirus | Bladder cancer | radiation therapy | MRE11 COMPLEX | DNA-DAMAGE | RECEPTOR | INHIBITION | REPLICATION | NUCLEAR SCIENCE & TECHNOLOGY | PROSTATE-CANCER | BIOLOGY | INFECTION | ATM ACTIVATION | IONIZING-RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ANTITUMOR EFFICACY | Humans | Treatment Outcome | Cell Survival - radiation effects | Urinary Bladder Neoplasms - virology | Oncolytic Virotherapy - methods | Urinary Bladder Neoplasms - therapy | Oncolytic Viruses - physiology | Urinary Bladder Neoplasms - pathology | Adenoviridae - genetics | Cell Line, Tumor | Recombination, Genetic - genetics | Combined Modality Therapy - methods | Radiotherapy, Conformal - methods
gene therapy | oncolytic adenovirus | Bladder cancer | radiation therapy | MRE11 COMPLEX | DNA-DAMAGE | RECEPTOR | INHIBITION | REPLICATION | NUCLEAR SCIENCE & TECHNOLOGY | PROSTATE-CANCER | BIOLOGY | INFECTION | ATM ACTIVATION | IONIZING-RADIATION | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | ANTITUMOR EFFICACY | Humans | Treatment Outcome | Cell Survival - radiation effects | Urinary Bladder Neoplasms - virology | Oncolytic Virotherapy - methods | Urinary Bladder Neoplasms - therapy | Oncolytic Viruses - physiology | Urinary Bladder Neoplasms - pathology | Adenoviridae - genetics | Cell Line, Tumor | Recombination, Genetic - genetics | Combined Modality Therapy - methods | Radiotherapy, Conformal - methods
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2004, Volume 22, Issue 4, pp. 592 - 601
Purpose TNFerade is a replication deficient adenovector that expresses human tumor necrosis factor alpha under control of the radiation-inducible Egr-1...
TRIAL | CANCER-PATIENTS | THERAPY | INTERFERON-GAMMA | ONCOLOGY | SARCOMA | TNF-ALPHA | IONIZING-RADIATION | SOFT-TISSUE | ADENOVIRUS ONYX-015 | INTRAVENOUS-INFUSION | Gene Transfer Techniques | Promoter Regions, Genetic - radiation effects | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Combined Modality Therapy | Antineoplastic Agents - administration & dosage | Radiotherapy | Neoplasms - drug therapy | Dose-Response Relationship, Drug | Tumor Necrosis Factor-alpha - adverse effects | Antineoplastic Agents - adverse effects | Adenoviridae - genetics | Aged, 80 and over | Tumor Necrosis Factor-alpha - administration & dosage | Adult | Female | Aged | Genetic Vectors
TRIAL | CANCER-PATIENTS | THERAPY | INTERFERON-GAMMA | ONCOLOGY | SARCOMA | TNF-ALPHA | IONIZING-RADIATION | SOFT-TISSUE | ADENOVIRUS ONYX-015 | INTRAVENOUS-INFUSION | Gene Transfer Techniques | Promoter Regions, Genetic - radiation effects | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Combined Modality Therapy | Antineoplastic Agents - administration & dosage | Radiotherapy | Neoplasms - drug therapy | Dose-Response Relationship, Drug | Tumor Necrosis Factor-alpha - adverse effects | Antineoplastic Agents - adverse effects | Adenoviridae - genetics | Aged, 80 and over | Tumor Necrosis Factor-alpha - administration & dosage | Adult | Female | Aged | Genetic Vectors
Journal Article
Head & Neck, ISSN 1043-3074, 03/2014, Volume 36, Issue 3, pp. 411 - 418
Background Radioresistance remains a critical issue in the use of radiotherapy for the treatment of head and neck squamous cell carcinoma (HNSCC). This study...
telomerase | virotherapy | OBP‐301 | radiation sensitivity | head and neck squamous cell carcinoma | OBP-301 | Humans | DNA Repair - physiology | DNA Repair - radiation effects | Carcinoma, Squamous Cell - radiotherapy | Squamous Cell Carcinoma of Head and Neck | Telomerase - genetics | Adenoviridae - genetics | Female | Telomerase - metabolism | Disease Models, Animal | Radiation, Ionizing | Radiotherapy Dosage | Head and Neck Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Blotting, Western | Xenograft Model Antitumor Assays | Head and Neck Neoplasms - radiotherapy | Oncolytic Virotherapy - methods | Animals | Mice, Nude | Neoplastic Cells, Circulating | Mice | Mice, Inbred BALB C | Adenoviridae - metabolism | In Vitro Techniques | Squamous cell carcinoma | Nuclear radiation | Telomerase | Analysis | Adenoviruses
telomerase | virotherapy | OBP‐301 | radiation sensitivity | head and neck squamous cell carcinoma | OBP-301 | Humans | DNA Repair - physiology | DNA Repair - radiation effects | Carcinoma, Squamous Cell - radiotherapy | Squamous Cell Carcinoma of Head and Neck | Telomerase - genetics | Adenoviridae - genetics | Female | Telomerase - metabolism | Disease Models, Animal | Radiation, Ionizing | Radiotherapy Dosage | Head and Neck Neoplasms - therapy | Carcinoma, Squamous Cell - therapy | Blotting, Western | Xenograft Model Antitumor Assays | Head and Neck Neoplasms - radiotherapy | Oncolytic Virotherapy - methods | Animals | Mice, Nude | Neoplastic Cells, Circulating | Mice | Mice, Inbred BALB C | Adenoviridae - metabolism | In Vitro Techniques | Squamous cell carcinoma | Nuclear radiation | Telomerase | Analysis | Adenoviruses
Journal Article
Cancer Research, ISSN 0008-5472, 12/2007, Volume 67, Issue 24, pp. 11687 - 11695
Mesenchymal stem cells (MSC) migrate to and proliferate within sites of inflammation and tumors as part of the tissue remodeling process. Radiation increases...
MIGRATION | CAPACITY | CYTOKINES | VEHICLES | ONCOLOGY | CHEMOKINE | MICE | BONE | IONIZING-RADIATION | MARROW STROMAL CELLS | DELIVERY | Mammary Neoplasms, Animal - therapy | Luciferases - analysis | Stem Cells - radiation effects | Luciferases - genetics | Mesoderm - radiation effects | Stem Cell Transplantation | Mammary Neoplasms, Animal - pathology | Mammary Neoplasms, Animal - radiotherapy | Animals | Genetic Engineering | Transfection | Adenoviridae - genetics | Cell Line, Tumor | Mesoderm - physiology | Stem Cells - pathology | Neoplasms - radiotherapy | Stem Cells - physiology | Mice | Mice, Inbred BALB C | Neoplasms - pathology
MIGRATION | CAPACITY | CYTOKINES | VEHICLES | ONCOLOGY | CHEMOKINE | MICE | BONE | IONIZING-RADIATION | MARROW STROMAL CELLS | DELIVERY | Mammary Neoplasms, Animal - therapy | Luciferases - analysis | Stem Cells - radiation effects | Luciferases - genetics | Mesoderm - radiation effects | Stem Cell Transplantation | Mammary Neoplasms, Animal - pathology | Mammary Neoplasms, Animal - radiotherapy | Animals | Genetic Engineering | Transfection | Adenoviridae - genetics | Cell Line, Tumor | Mesoderm - physiology | Stem Cells - pathology | Neoplasms - radiotherapy | Stem Cells - physiology | Mice | Mice, Inbred BALB C | Neoplasms - pathology
Journal Article
Gene Therapy, ISSN 0969-7128, 02/2017, Volume 24, Issue 2, pp. 104 - 112
Forkhead transcription factor 3 (Foxp3) has a critical role in regulatory T cells (Treg). There are an increasing number of researches concerning the functions...
MEDICINE, RESEARCH & EXPERIMENTAL | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | CANCER | IRRADIATION | GROWTH-FACTOR-BETA | THERAPY | INHIBITION | INDUCED PULMONARY-FIBROSIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STEREOTACTIC BODY RADIOTHERAPY | INFLAMMATION | GENETICS & HEREDITY | Genetic Therapy | Epithelial Cells - radiation effects | Radiation Pneumonitis - etiology | Epithelial Cells - metabolism | Pneumonia - etiology | Genetic Vectors - administration & dosage | Mice, Inbred C57BL | Pneumonia - prevention & control | X-Rays - adverse effects | Forkhead Transcription Factors - genetics | Radiation Pneumonitis - prevention & control | T-Lymphocytes, Regulatory - immunology | Animals | Epithelial Cells - immunology | Adenoviridae - genetics | Female | Lung - radiation effects | Lung - metabolism | Mice | Lung - immunology | Transcription factors | Usage | Care and treatment | Pneumonia | Patient outcomes | Bacterial pneumonia | Development and progression | Gene expression | Adenoviruses | Genetic aspects | Gene therapy | Health aspects | Methods | Protein expression | Inflammation | Lung diseases
MEDICINE, RESEARCH & EXPERIMENTAL | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | CANCER | IRRADIATION | GROWTH-FACTOR-BETA | THERAPY | INHIBITION | INDUCED PULMONARY-FIBROSIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | STEREOTACTIC BODY RADIOTHERAPY | INFLAMMATION | GENETICS & HEREDITY | Genetic Therapy | Epithelial Cells - radiation effects | Radiation Pneumonitis - etiology | Epithelial Cells - metabolism | Pneumonia - etiology | Genetic Vectors - administration & dosage | Mice, Inbred C57BL | Pneumonia - prevention & control | X-Rays - adverse effects | Forkhead Transcription Factors - genetics | Radiation Pneumonitis - prevention & control | T-Lymphocytes, Regulatory - immunology | Animals | Epithelial Cells - immunology | Adenoviridae - genetics | Female | Lung - radiation effects | Lung - metabolism | Mice | Lung - immunology | Transcription factors | Usage | Care and treatment | Pneumonia | Patient outcomes | Bacterial pneumonia | Development and progression | Gene expression | Adenoviruses | Genetic aspects | Gene therapy | Health aspects | Methods | Protein expression | Inflammation | Lung diseases
Journal Article
Cancer Research, ISSN 0008-5472, 11/2010, Volume 70, Issue 22, pp. 9339 - 9348
The inability to repair DNA double-strand breaks (DSB) leads to radiosensitization, such that ionizing radiation combined with molecular inhibition of cellular...
MRE11 COMPLEX | ONCOLOGY | REPLICATION-SELECTIVE ADENOVIRUS | E1B 55-KILODALTON PROTEIN | ATM ACTIVATION | ATAXIA-TELANGIECTASIA | UP-REGULATION | HUMAN TUMOR-CELLS | S-PHASE CHECKPOINT | H2AX PHOSPHORYLATION | STRAND BREAKS | Apoptosis - radiation effects | Humans | Cell Survival - genetics | DNA Repair - radiation effects | Apoptosis - genetics | DNA Breaks, Double-Stranded - radiation effects | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Neoplasms - therapy | Flow Cytometry | Telomerase - genetics | Neoplasms - genetics | DNA Repair Enzymes - metabolism | Adenoviridae - genetics | Female | Telomerase - metabolism | Adenovirus E1B Proteins - metabolism | Esophageal Neoplasms - therapy | Radiation, Ionizing | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Combined Modality Therapy | Cell Survival - radiation effects | Blotting, Western | Xenograft Model Antitumor Assays | Oncolytic Virotherapy - methods | Animals | Esophageal Neoplasms - genetics | Mice, Nude | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Adenoviridae - metabolism
MRE11 COMPLEX | ONCOLOGY | REPLICATION-SELECTIVE ADENOVIRUS | E1B 55-KILODALTON PROTEIN | ATM ACTIVATION | ATAXIA-TELANGIECTASIA | UP-REGULATION | HUMAN TUMOR-CELLS | S-PHASE CHECKPOINT | H2AX PHOSPHORYLATION | STRAND BREAKS | Apoptosis - radiation effects | Humans | Cell Survival - genetics | DNA Repair - radiation effects | Apoptosis - genetics | DNA Breaks, Double-Stranded - radiation effects | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Neoplasms - therapy | Flow Cytometry | Telomerase - genetics | Neoplasms - genetics | DNA Repair Enzymes - metabolism | Adenoviridae - genetics | Female | Telomerase - metabolism | Adenovirus E1B Proteins - metabolism | Esophageal Neoplasms - therapy | Radiation, Ionizing | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Combined Modality Therapy | Cell Survival - radiation effects | Blotting, Western | Xenograft Model Antitumor Assays | Oncolytic Virotherapy - methods | Animals | Esophageal Neoplasms - genetics | Mice, Nude | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Adenoviridae - metabolism
Journal Article
Applied and Environmental Microbiology, ISSN 0099-2240, 01/2009, Volume 75, Issue 1, pp. 23 - 28
Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit...
REPAIR | XERODERMA-PIGMENTOSUM | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LIGHT | COMPARATIVE INACTIVATION | CHLORINE | MICROBIOLOGY | CELL-CULTURE | PCR AMPLIFICATION | TYPE-2 | FIBROBLASTS | VIRUSES | Cell Line | Virus Inactivation - radiation effects | Adenoviridae - radiation effects | Ultraviolet Rays | Adenoviridae - growth & development | Humans | Disinfection - methods | Polymerase Chain Reaction | Virus Cultivation | DNA Damage | Microbial Viability | DNA, Viral - radiation effects | Polymerase chain reaction | Usage | Ultraviolet radiation | Adenoviruses | DNA damage | Analysis | Genetic aspects | Public Health Microbiology
REPAIR | XERODERMA-PIGMENTOSUM | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | LIGHT | COMPARATIVE INACTIVATION | CHLORINE | MICROBIOLOGY | CELL-CULTURE | PCR AMPLIFICATION | TYPE-2 | FIBROBLASTS | VIRUSES | Cell Line | Virus Inactivation - radiation effects | Adenoviridae - radiation effects | Ultraviolet Rays | Adenoviridae - growth & development | Humans | Disinfection - methods | Polymerase Chain Reaction | Virus Cultivation | DNA Damage | Microbial Viability | DNA, Viral - radiation effects | Polymerase chain reaction | Usage | Ultraviolet radiation | Adenoviruses | DNA damage | Analysis | Genetic aspects | Public Health Microbiology
Journal Article
Human Gene Therapy, ISSN 1043-0342, 05/2016, Volume 27, Issue 5, pp. 39 - 399
Irreversible hypofunction of salivary glands is common in head and neck cancer survivors treated with radiotherapy and can only be temporarily relieved with...
Research Articles | MEDICINE, RESEARCH & EXPERIMENTAL | SELF-DUPLICATION RATHER | SONIC HEDGEHOG | GLAND HYPOFUNCTION | NECK CANCER | INDUCED SALIVARY HYPOFUNCTION | STEM-CELL DIFFERENTIATION | PARASYMPATHETIC INNERVATION | TRANSIENT ACTIVATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ENDOTHELIAL-CELLS | GENETICS & HEREDITY | PREVENTS RADIATION-DAMAGE | Genetic Therapy | Microvessels - metabolism | Radiation | Hedgehog Proteins - metabolism | Microvessels - pathology | Male | Hedgehog Proteins - genetics | Xerostomia - metabolism | Adenoviridae - genetics | Female | Disease Models, Animal | Microvessels - radiation effects | Gene Transfer Techniques | Transduction, Genetic | Signal Transduction | Submandibular Gland - metabolism | Mice, Transgenic | Submandibular Gland - innervation | Genetic Vectors - genetics | Regeneration | Animals | Submandibular Gland - physiopathology | Xerostomia - therapy | Mice | Xerostomia - etiology | Innervation | Activation | Males | Angiogenesis | Signal transduction | Rodents | Expression vectors | Acinar cells | Gene transfer | Salivary glands | Secretion | Transgenic mice | Feasibility studies | Data processing | Salivary gland | Radiation therapy | Neurotrophic factors | Progenitor cells | Progeny | Signaling | Hedgehog protein | Green fluorescent protein | Stem cells | Cells (biology) | Irradiation | Head and neck cancer | Microvasculature | Saliva | Radiation damage | Parasympathetic nervous system | Cancer
Research Articles | MEDICINE, RESEARCH & EXPERIMENTAL | SELF-DUPLICATION RATHER | SONIC HEDGEHOG | GLAND HYPOFUNCTION | NECK CANCER | INDUCED SALIVARY HYPOFUNCTION | STEM-CELL DIFFERENTIATION | PARASYMPATHETIC INNERVATION | TRANSIENT ACTIVATION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ENDOTHELIAL-CELLS | GENETICS & HEREDITY | PREVENTS RADIATION-DAMAGE | Genetic Therapy | Microvessels - metabolism | Radiation | Hedgehog Proteins - metabolism | Microvessels - pathology | Male | Hedgehog Proteins - genetics | Xerostomia - metabolism | Adenoviridae - genetics | Female | Disease Models, Animal | Microvessels - radiation effects | Gene Transfer Techniques | Transduction, Genetic | Signal Transduction | Submandibular Gland - metabolism | Mice, Transgenic | Submandibular Gland - innervation | Genetic Vectors - genetics | Regeneration | Animals | Submandibular Gland - physiopathology | Xerostomia - therapy | Mice | Xerostomia - etiology | Innervation | Activation | Males | Angiogenesis | Signal transduction | Rodents | Expression vectors | Acinar cells | Gene transfer | Salivary glands | Secretion | Transgenic mice | Feasibility studies | Data processing | Salivary gland | Radiation therapy | Neurotrophic factors | Progenitor cells | Progeny | Signaling | Hedgehog protein | Green fluorescent protein | Stem cells | Cells (biology) | Irradiation | Head and neck cancer | Microvasculature | Saliva | Radiation damage | Parasympathetic nervous system | Cancer
Journal Article
Molecular Oncology, ISSN 1574-7891, 08/2012, Volume 6, Issue 4, pp. 383 - 391
Combinatorial therapy is the current trend of the development of novel cancer treatments due to the high heterogenous nature of solid tumors. In this study, we...
Conditionally replicating adenoviruses | Melanoma | Interleukin-24 | Radiation | Apoptosis | MDA-7/IL-24 | Conditionally | MALIGNANT-MELANOMA | COMBINATION | SUICIDE GENE-THERAPY | BCL-2 | ONCOLOGY | COLORECTAL-CANCER | ENHANCED ANTITUMOR-ACTIVITY | PROSTATE-CANCER | replicating adenoviruses | IONIZING-RADIATION | ONCOLYTIC ADENOVIRUS | Immunohistochemistry | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Up-Regulation - radiation effects | Male | Down-Regulation - radiation effects | Drug Delivery Systems | Adenoviridae - radiation effects | Mitochondria - radiation effects | Interleukins - pharmacology | Cell Survival - drug effects | Virus Replication - drug effects | Interleukins - therapeutic use | Melanoma - radiotherapy | bcl-2-Associated X Protein - metabolism | Adenoviridae - physiology | Combined Modality Therapy | Mitochondria - metabolism | Melanoma - pathology | Mitochondria - drug effects | Down-Regulation - drug effects | Cell Survival - radiation effects | Up-Regulation - drug effects | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Melanoma - drug therapy | Cell Line, Tumor | Virus Replication - radiation effects | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Virus Replication - physiology | Adenoviridae - drug effects | Cell Proliferation - radiation effects | Medical colleges | Oncology, Experimental | Research | Radiotherapy | Antineoplastic agents | Antimitotic agents | Interleukins | Emissions (Pollution) | Adenoviruses | Health aspects | Cancer | Cell proliferation | Immunoglobulins | Bax protein | Cytokines | Caspase | Radiation therapy | Drug resistance | Cancer therapies | Skin cancer | Studies | Proteins | Chemotherapy | Solid tumors | Gene therapy | Papers | Paper
Conditionally replicating adenoviruses | Melanoma | Interleukin-24 | Radiation | Apoptosis | MDA-7/IL-24 | Conditionally | MALIGNANT-MELANOMA | COMBINATION | SUICIDE GENE-THERAPY | BCL-2 | ONCOLOGY | COLORECTAL-CANCER | ENHANCED ANTITUMOR-ACTIVITY | PROSTATE-CANCER | replicating adenoviruses | IONIZING-RADIATION | ONCOLYTIC ADENOVIRUS | Immunohistochemistry | Apoptosis - drug effects | Apoptosis - radiation effects | Humans | Up-Regulation - radiation effects | Male | Down-Regulation - radiation effects | Drug Delivery Systems | Adenoviridae - radiation effects | Mitochondria - radiation effects | Interleukins - pharmacology | Cell Survival - drug effects | Virus Replication - drug effects | Interleukins - therapeutic use | Melanoma - radiotherapy | bcl-2-Associated X Protein - metabolism | Adenoviridae - physiology | Combined Modality Therapy | Mitochondria - metabolism | Melanoma - pathology | Mitochondria - drug effects | Down-Regulation - drug effects | Cell Survival - radiation effects | Up-Regulation - drug effects | Xenograft Model Antitumor Assays | Animals | Mice, Nude | Melanoma - drug therapy | Cell Line, Tumor | Virus Replication - radiation effects | Cell Proliferation - drug effects | Mice | Mice, Inbred BALB C | Virus Replication - physiology | Adenoviridae - drug effects | Cell Proliferation - radiation effects | Medical colleges | Oncology, Experimental | Research | Radiotherapy | Antineoplastic agents | Antimitotic agents | Interleukins | Emissions (Pollution) | Adenoviruses | Health aspects | Cancer | Cell proliferation | Immunoglobulins | Bax protein | Cytokines | Caspase | Radiation therapy | Drug resistance | Cancer therapies | Skin cancer | Studies | Proteins | Chemotherapy | Solid tumors | Gene therapy | Papers | Paper
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e69025
These studies define a new mechanism-based approach to radiosensitize tumor cure by single dose radiotherapy (SDRT). Published evidence indicates that SDRT...
GLIOMA-CELLS | APOPTOSIS | IN-VITRO | ACTIVATION | MULTIDISCIPLINARY SCIENCES | INTENSITY-MODULATED RADIOTHERAPY | FIBROBLAST-GROWTH-FACTOR | BODY RADIATION-THERAPY | GENE-THERAPY | SELECTIVE ENHANCEMENT | VECTOR | Human Umbilical Vein Endothelial Cells | Sphingomyelin Phosphodiesterase - genetics | Melanoma, Experimental - enzymology | Humans | Melanoma, Experimental - radiotherapy | Radiation Tolerance | Radiation-Sensitizing Agents - pharmacology | Neovascularization, Pathologic | Male | Immunoenzyme Techniques | Fibrosarcoma - radiotherapy | Melanoma, Experimental - prevention & control | Animals | Endothelium, Vascular - metabolism | Sphingomyelin Phosphodiesterase - metabolism | Adenoviridae - genetics | Endothelium, Vascular - pathology | Mice | Fibrosarcoma - enzymology | Endothelium, Vascular - radiation effects | Apoptosis | Fibrosarcoma - prevention & control | Medical research | Ionizing radiation | Genes | Adenoviruses | Stem cells | Medicine, Experimental | Gene therapy | Radiotherapy | Health aspects | Tumors | Endothelium | Cycles | Intravenous administration | Laboratories | Radiation | Oncology | Lethality | Tissues | Cancer therapies | Signal transduction | Angiogenesis | Biological effects | Intestine | Pretreatment | Deoxyribonucleic acid--DNA | Translocation | Cures | Radiation therapy | Gene expression | Sphingomyelin phosphodiesterase | Studies | Overexpression | Acids | Biopsy | Crypts | Hypoxia | Microvasculature | Radiation damage | Impact damage | Deoxyribonucleic acid | DNA
GLIOMA-CELLS | APOPTOSIS | IN-VITRO | ACTIVATION | MULTIDISCIPLINARY SCIENCES | INTENSITY-MODULATED RADIOTHERAPY | FIBROBLAST-GROWTH-FACTOR | BODY RADIATION-THERAPY | GENE-THERAPY | SELECTIVE ENHANCEMENT | VECTOR | Human Umbilical Vein Endothelial Cells | Sphingomyelin Phosphodiesterase - genetics | Melanoma, Experimental - enzymology | Humans | Melanoma, Experimental - radiotherapy | Radiation Tolerance | Radiation-Sensitizing Agents - pharmacology | Neovascularization, Pathologic | Male | Immunoenzyme Techniques | Fibrosarcoma - radiotherapy | Melanoma, Experimental - prevention & control | Animals | Endothelium, Vascular - metabolism | Sphingomyelin Phosphodiesterase - metabolism | Adenoviridae - genetics | Endothelium, Vascular - pathology | Mice | Fibrosarcoma - enzymology | Endothelium, Vascular - radiation effects | Apoptosis | Fibrosarcoma - prevention & control | Medical research | Ionizing radiation | Genes | Adenoviruses | Stem cells | Medicine, Experimental | Gene therapy | Radiotherapy | Health aspects | Tumors | Endothelium | Cycles | Intravenous administration | Laboratories | Radiation | Oncology | Lethality | Tissues | Cancer therapies | Signal transduction | Angiogenesis | Biological effects | Intestine | Pretreatment | Deoxyribonucleic acid--DNA | Translocation | Cures | Radiation therapy | Gene expression | Sphingomyelin phosphodiesterase | Studies | Overexpression | Acids | Biopsy | Crypts | Hypoxia | Microvasculature | Radiation damage | Impact damage | Deoxyribonucleic acid | DNA
Journal Article