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Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 11, pp. 1458 - 1463
Highlights ► Piglets orally inoculated with an E. coli strain expressing a holotoxin-like adhesin–toxoid fusion antigen 1FaeG-FedF-LTA2 :5LTB were protected... 
Allergy and Immunology | K88 (F4) | Live attenuated vaccine | Heat-labile toxin (LT) | F18, 987P | Enterotoxigenic E. coli (ETEC) | Diarrhea | Porcine post-weaning diarrhea (PWD) | ANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | HEAT-LABILE ENTEROTOXIN | COLIBACILLOSIS | PREVALENCE | MODEL | IMMUNOLOGY | VIRULENCE GENES | ADHERENCE | FIMBRIAE | CHOLERA-TOXIN | Escherichia coli Infections - prevention & control | Diarrhea - prevention & control | Neutralization Tests | Vaccines, Synthetic - immunology | Antibodies, Bacterial - analysis | Bacterial Toxins - antagonists & inhibitors | Serum - immunology | Adhesins, Bacterial - metabolism | Vaccines, Synthetic - adverse effects | Intestinal Mucosa - immunology | Swine | Vaccines, Attenuated - administration & dosage | Escherichia coli Infections - veterinary | Enterotoxigenic Escherichia coli - genetics | Antibodies, Bacterial - blood | Administration, Oral | Intestine, Small - microbiology | Vaccines, Synthetic - genetics | Bacterial Load | Swine Diseases - prevention & control | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Vaccines, Attenuated - immunology | Animals | Escherichia coli Vaccines - adverse effects | Escherichia coli Vaccines - genetics | Vaccines, Synthetic - administration & dosage | Escherichia coli Vaccines - immunology | Vaccines, Attenuated - adverse effects | Vaccines, Attenuated - genetics | Phosphates | Monoclonal antibodies | Immunization | Biological products | Escherichia coli
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 12, pp. 4555 - 4564
Globally, enterotoxigenic Escherichia coli (ETEC) is a leading cause of childhood and travelers' diarrhea, for which an effective vaccine is needed. Prevalent... 
COLONIZATION FACTOR ANTIGENS | HEAT-LABILE TOXIN | INFECTIOUS DISEASES | IMMUNOGENICITY | TRAVELERS DIARRHEA | DNA VACCINE | CFA/I FIMBRIAE | INFANT MOUSE MODEL | DOUBLE-BLIND | IMMUNOLOGY | VIRULENCE | SUBUNIT | Escherichia coli Infections - mortality | Milk - chemistry | Dose-Response Relationship, Immunologic | Immune Sera - chemistry | Escherichia coli Infections - prevention & control | Immunoglobulin A - biosynthesis | Adhesins, Bacterial - genetics | Escherichia coli Infections - genetics | Antibodies, Bacterial - biosynthesis | Escherichia coli Proteins - administration & dosage | Immunoglobulin G - biosynthesis | Cattle | Female | Mice, Inbred DBA | Escherichia coli Proteins - immunology | Fimbriae, Bacterial - immunology | Milk - immunology | Enterotoxigenic Escherichia coli - genetics | Fimbriae Proteins - immunology | Gene Expression | Adhesins, Bacterial - administration & dosage | Enterotoxigenic Escherichia coli - drug effects | Fimbriae, Bacterial - chemistry | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Pregnancy | Animals | Fimbriae Proteins - genetics | Survival Analysis | Vaccines, Attenuated | Escherichia coli Proteins - genetics | Immunization, Passive | Escherichia coli Infections - immunology | Escherichia coli Vaccines - genetics | Fimbriae Proteins - administration & dosage | Mice | Adhesins, Bacterial - immunology | Escherichia coli Vaccines - immunology | Microbial Immunity and Vaccines
Journal Article
Veterinary Microbiology, ISSN 0378-1135, 08/2014, Volume 172, Issue 1-2, pp. 13 - 22
•We provide an overview APEC's virulence factors.•Critically review attempts to develop a vaccine against APEC.•We analyze the only commercially available... 
IROMPs | Avian pathogenic E. coli (APEC) | Septicemia | Airsacculitis | Fimbriae | Iss | Aerobactin | Chicken | Vaccine | Antimicrobial resistance | Broiler | EXPERIMENTALLY INOCULATED CHICKENS | FIMH-ADHESIN | INVIVO CHARACTERIZATION | MICROBIOLOGY | PASSIVE-IMMUNIZATION | COMPLEMENT RESISTANCE | INACTIVATED VACCINES | LABORATORY TRIALS | VIRULENCE FACTORS | VETERINARY SCIENCES | HEALTHY BIRDS | ANTIBODY-RESPONSES | Virulence Factors - genetics | Age Factors | Escherichia coli Infections - prevention & control | Hydroxamic Acids - immunology | Vaccination - veterinary | Virulence Factors - immunology | Fimbriae, Bacterial - genetics | Escherichia coli - pathogenicity | Escherichia coli - metabolism | Escherichia coli Infections - veterinary | Escherichia coli Proteins - immunology | Fimbriae, Bacterial - immunology | Escherichia coli Vaccines - classification | Bacterial Outer Membrane Proteins - genetics | Gene Expression | Bacterial Outer Membrane Proteins - immunology | Escherichia coli - immunology | Escherichia coli Infections - microbiology | Escherichia coli Vaccines - biosynthesis | Chickens - microbiology | Iron - metabolism | Escherichia coli Vaccines - administration & dosage | Animals | Poultry Diseases - prevention & control | Poultry Diseases - immunology | Poultry Diseases - microbiology | Escherichia coli Proteins - genetics | Escherichia coli Infections - immunology | Escherichia coli Vaccines - immunology | Lung diseases | Analysis | Vaccination | Escherichia coli
Journal Article
Vaccine, ISSN 0264-410X, 2009, Volume 28, Issue 5, pp. 1422 - 1428
Abstract Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is a human pathogen that can cause gastrointestinal disease with potentially fatal consequences as a... 
Allergy and Immunology | Intimin | E. coli O157 | Type III secretion | Tir | Cattle | EspA | ANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | III SECRETED PROTEINS | VACCINATION | O157-H7 INFECTION | SHIGA-TOXIN | IMMUNOLOGY | INTESTINAL COLONIZATION | RESPONSES | CALVES | EFFACING LESIONS | TERMINAL RECTUM | Immunity, Mucosal - immunology | Escherichia coli Infections - prevention & control | Adhesins, Bacterial - genetics | Humans | Antigens, Bacterial - immunology | Male | Escherichia coli Vaccines - pharmacology | Antigens, Bacterial - genetics | Flagellin - pharmacology | Immunity, Mucosal - drug effects | Escherichia coli Infections - genetics | Escherichia coli Proteins - pharmacology | Flagellin - genetics | Escherichia coli Proteins - immunology | Bacterial Adhesion - drug effects | Flagellin - immunology | Escherichia coli O157 - genetics | Bacterial Adhesion - immunology | Antigens, Bacterial - pharmacology | Shiga Toxin - immunology | Receptors, Cell Surface - immunology | Animals | Adhesins, Bacterial - pharmacology | Escherichia coli Proteins - genetics | Antibodies, Bacterial - immunology | Escherichia coli Infections - immunology | Escherichia coli Vaccines - genetics | Adhesins, Bacterial - immunology | Escherichia coli Vaccines - immunology | Escherichia coli O157 - immunology | Receptors, Cell Surface - genetics
Journal Article
Infection and Immunity, ISSN 0019-9567, 07/2007, Volume 75, Issue 7, pp. 3233 - 3244
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
REGULATORY CROSS-TALK | TYPE-1 FIMBRIAE | P-FIMBRIAE | INFECTIOUS DISEASES | CELL-AGGREGATION | OUTER-MEMBRANE PROTEIN | COLONY MORPHOLOGY | BACTERIAL ADHESINS | IMMUNOLOGY | AUTOTRANSPORTER PROTEIN | EXPRESSION | BIOFILM FORMATION | Virulence Factors - genetics | Adhesins, Bacterial - genetics | Humans | Virulence | Biofilms - growth & development | Antigens, Bacterial - genetics | Adhesins, Bacterial - metabolism | Escherichia coli K12 - metabolism | Time Factors | Escherichia coli - pathogenicity | Gene Deletion | Escherichia coli - metabolism | Female | Urinary Tract Infections - microbiology | Urinary Bladder - microbiology | Escherichia coli - growth & development | Bacterial Outer Membrane Proteins - genetics | Escherichia coli K12 - pathogenicity | Adhesins, Escherichia coli | Mice, Inbred C57BL | Escherichia coli Infections - microbiology | Escherichia coli Proteins - metabolism | Bacterial Adhesion | Animals | Bacterial Outer Membrane Proteins - metabolism | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Virulence Factors - metabolism | Mice | Escherichia coli K12 - genetics | Antigens, Bacterial - metabolism | Bacterial Outer Membrane Proteins | Escherichia coli | Antigens, Bacterial | Adhesins, Bacterial | Virulence Factors | Escherichia coli K12 | Life Sciences | Microbiology and Parasitology | Urinary Tract Infections | Biofilms | Escherichia coli Proteins | Escherichia coli Infections | Urinary Bladder | Molecular Pathogenesis
Journal Article
by Yu, M and Qi, R and Chen, C and Yin, J and Ma, S and Shi, W and Wu, Y and Ge, J and Jiang, Y and Tang, L and Xu, Y and Li, Y
Journal of Applied Microbiology, ISSN 1364-5072, 02/2017, Volume 122, Issue 2, pp. 506 - 515
Aims The aims of this study were to develop an effective oral vaccine against enterotoxigenic Escherichia coli (ETEC) infection and to design new and more... 
heat‐labile enterotoxin A subunit | Lactobacillus casei | fimbriae adhesin FaeG | heat‐labile enterotoxin B subunit | immunogenicity | heat-labile enterotoxin A subunit | heat-labile enterotoxin B subunit | VIRUS | PROTECTION | VACCINE | MICROBIOLOGY | MUCOSAL | IMMUNIZATION | EPITOPE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | IMMUNE-RESPONSES | PIGLETS | SUBUNIT | ANTIGEN | Adjuvants, Immunologic - administration & dosage | Escherichia coli Infections - prevention & control | Immunity, Mucosal | Adhesins, Escherichia coli - genetics | Lymphocytes - immunology | Enterotoxins - immunology | Escherichia coli Proteins - administration & dosage | Swine | Adhesins, Escherichia coli - immunology | Female | Escherichia coli Infections - veterinary | Escherichia coli Proteins - immunology | Lactobacillus casei - genetics | Fimbriae, Bacterial | Specific Pathogen-Free Organisms | Administration, Oral | Bacterial Toxins - immunology | Swine Diseases - immunology | Lymphocytes - cytology | Swine Diseases - prevention & control | Enterotoxigenic Escherichia coli - immunology | Escherichia coli Vaccines - administration & dosage | Enterotoxins - administration & dosage | Animals | Bacterial Toxins - administration & dosage | Escherichia coli Infections - immunology | Mice | Mice, Inbred BALB C | Escherichia coli Vaccines - immunology | Enterotoxigenic Escherichia coli - classification | Toxins | Bacterial infections | Vaccines | E coli | Microbiology
Journal Article
Vaccine, ISSN 0264-410X, 2012, Volume 31, Issue 8, pp. 1210 - 1216
Highlights ► We describe the first UTI vaccine formulations based on the FliC or Montanide. ► FliC or Montanide induced strong humoral and cell immune... 
Allergy and Immunology | Flagellin | Urinary tract infection | Adjuvant | Vaccine | Montanide | FimH | MEDICINE, RESEARCH & EXPERIMENTAL | UROPATHOGENIC ESCHERICHIA-COLI | EFFECTIVE ADJUVANT | INNATE | TYPHIMURIUM | COLONIZATION | MUCOSAL | IMMUNOLOGY | IMMUNIZATION | INTRACELLULAR BACTERIAL COMMUNITIES | EXPRESSION | FUSION PROTEINS | Recombinant Fusion Proteins - immunology | Adjuvants, Immunologic - administration & dosage | Immunoglobulin G - blood | Escherichia coli Infections - prevention & control | Molecular Sequence Data | Urinary Tract Infections - prevention & control | Vaccines, Synthetic - immunology | Uropathogenic Escherichia coli - immunology | Adhesins, Escherichia coli - genetics | Vaccination - methods | Adhesins, Escherichia coli - immunology | Female | Escherichia coli Proteins - immunology | Urinary Bladder - microbiology | Antibodies, Bacterial - blood | Fimbriae Proteins - immunology | Disease Models, Animal | Interferon-gamma - secretion | Vaccines, Synthetic - genetics | Uropathogenic Escherichia coli - genetics | Sequence Analysis, DNA | Escherichia coli Vaccines - administration & dosage | Interleukin-4 - secretion | Animals | Fimbriae Proteins - genetics | Escherichia coli Proteins - genetics | Recombinant Fusion Proteins - genetics | Escherichia coli Infections - immunology | T-Lymphocytes - immunology | Escherichia coli Vaccines - genetics | Mice | Mice, Inbred BALB C | Vaccines, Synthetic - administration & dosage | Escherichia coli Vaccines - immunology | Urinary Tract Infections - immunology | Urinary tract infections | Health aspects | Immunoglobulin G | Vaccination | Medical research | Antigens | Candidates | Cytokines | Bladder | Infections | Vaccines | Urinary tract diseases | Proteins | Studies | Cell growth | Urogenital system | Immune system
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2014, Volume 10, Issue 9, p. e1004404
Enteroaggregative Escherichia coli (EAEC) is a leading cause of acute and persistent diarrhea worldwide. A recently emerged Shiga-toxin-producing strain of... 
HEMOLYTIC-UREMIC SYNDROME | PILUS SUBUNITS | MICROBIOLOGY | DISULFIDE BOND | FIBRONECTIN-BINDING | PERSISTENT DIARRHEA | INTESTINAL-CELLS | VIROLOGY | EPITHELIAL-CELLS | YERSINIA-PESTIS | DRIVES FIBER FORMATION | PARASITOLOGY | AFA-3 GENE-CLUSTER | Humans | Molecular Sequence Data | Crystallography, X-Ray | Immunoblotting | Host-Pathogen Interactions - immunology | Adhesins, Escherichia coli - genetics | Intestinal Mucosa - immunology | Escherichia coli - pathogenicity | Adhesins, Escherichia coli - immunology | Escherichia coli Proteins - immunology | Escherichia coli - growth & development | Amino Acid Sequence | Mutagenesis, Site-Directed | Magnetic Resonance Spectroscopy | Bacterial Adhesion - immunology | Escherichia coli - immunology | Escherichia coli Infections - microbiology | Fimbriae, Bacterial - chemistry | Models, Molecular | Escherichia coli Proteins - metabolism | Intestinal Mucosa - microbiology | Mutation - genetics | Fibronectins - metabolism | Sequence Homology, Amino Acid | Escherichia coli - genetics | Escherichia coli Proteins - genetics | Escherichia coli Infections - immunology | Protein Conformation | Escherichia coli Proteins - chemistry | Microscopy, Fluorescence | Intestinal Mucosa - pathology | Mortality | Japan | Escherichia coli | Distribution | Diarrhea | Escherichia coli infections | Maryland | Risk factors | Microbiology | Mikrobiologi | Proteins | E coli | Developing countries | LDCs | Experiments | Crystallography | Bacteriology | Public health | Binding sites
Journal Article
Infection and Immunity, ISSN 0019-9567, 01/2013, Volume 81, Issue 1, pp. 259 - 270
Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit... 
MOLECULAR CHARACTERIZATION | INTESTINAL COLONIZATION | OUTER-MEMBRANE VESICLES | VACCINE CANDIDATES | MURINE MODEL | INFECTIOUS DISEASES | HEAT-LABILE ENTEROTOXIN | TOXIN DELIVERY | IMMUNE-RESPONSES | CYCLIC DI-GMP | IMMUNOLOGY | MAMMALIAN-CELLS | Epithelial Cells - metabolism | Gene Expression - genetics | Adhesins, Bacterial - genetics | Humans | Virulence | Intestines - metabolism | Transcriptome - immunology | Cyclic GMP - immunology | Promoter Regions, Genetic - genetics | Intestines - immunology | Host-Pathogen Interactions - immunology | DNA-Binding Proteins - metabolism | Adhesins, Bacterial - metabolism | Receptors, Cyclic AMP - metabolism | Escherichia coli Infections - genetics | Cyclic GMP - analogs & derivatives | Enterotoxigenic Escherichia coli - pathogenicity | Gene Expression - immunology | Antigens, Surface - metabolism | Escherichia coli Proteins - immunology | Receptors, Cyclic AMP - genetics | Enterotoxigenic Escherichia coli - genetics | Caco-2 Cells | DNA-Binding Proteins - immunology | Antigens, Surface - genetics | Escherichia coli Infections - microbiology | Escherichia coli Proteins - metabolism | Escherichia coli Infections - metabolism | Transcriptome - genetics | DNA-Binding Proteins - genetics | Enterotoxigenic Escherichia coli - immunology | Intestines - microbiology | Cyclic GMP - metabolism | Host-Pathogen Interactions - genetics | Epithelial Cells - immunology | Epithelial Cells - microbiology | Cyclic GMP - genetics | Cell Line, Tumor | Escherichia coli Proteins - genetics | Transcription, Genetic - immunology | Escherichia coli Infections - immunology | Promoter Regions, Genetic - immunology | Transcription, Genetic - genetics | Adhesins, Bacterial - immunology | Receptors, Cyclic AMP - immunology | Antigens, Surface - immunology | Cellular Microbiology | Pathogen-Host Cell Molecular Interactions
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