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by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and Drong, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian’an and Randall, Joshua C and Scherag, André and Vedantam, Sailaja and Wood, Andrew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and Van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Warwick Daw, E and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Friedrich, Nele and Garcia, Melissa E and Giedraitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Nature (London), ISSN 1476-4687, 2015, Volume 518, Issue 7538, pp. 187 - 196
.... To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related... 
ABDOMINAL ADIPOSITY | METAANALYSIS | VARIANTS | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | GLYCEMIC TRAITS | RISK | FALSE DISCOVERY | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Endokrinologi och diabetes | Public Health, Global Health, Social Medicine and Epidemiology | Endocrinology and Diabetes
Journal Article
by Locke, Adam E and Kahali, Bratati and Berndt, Sonja I and Justice, Anne E and Pers, Tune H and Day, Felix R and Powell, Corey and Vedantam, Sailaja and Buchkovich, Martin L and Yang, Jian and Croteau-Chonka, Damien C and Esko, Tonu and Fall, Tove and Ferreira, Teresa and Gustafsson, Stefan and Kutalik, Zoltán and Luan, Jian’an and Mägi, Reedik and Randall, Joshua C and Winkler, Thomas W and Wood, Andrew R and Workalemahu, Tsegaselassie and Faul, Jessica D and Smith, Jennifer A and Hua Zhao, Jing and Zhao, Wei and Chen, Jin and Fehrmann, Rudolf and Hedman, Åsa K and Karjalainen, Juha and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bolton, Jennifer L and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Deng, Guohong and Ehret, Georg B and Feenstra, Bjarke and Feitosa, Mary F and Fischer, Krista and Goel, Anuj and Gong, Jian and Jackson, Anne U and Kanoni, Stavroula and Kleber, Marcus E and Kristiansson, Kati and Lim, Unhee and Lotay, Vaneet and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Medland, Sarah E and Nalls, Michael A and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Shungin, Dmitry and Stančáková, Alena and Strawbridge, Rona J and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and Trompet, Stella and van der Laan, Sander W and van Setten, Jessica and Van Vliet-Ostaptchouk, Jana V and Wang, Zhaoming and Yengo, Loïc and Zhang, Weihua and Isaacs, Aaron and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Attwood, Antony P and Bandinelli, Stefania and Barrett, Amy and Bas, Isabelita N and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blagieva, Roza and Blüher, Matthias and Böhringer, Stefan and Bonnycastle, Lori L and Böttcher, Yvonne and Boyd, Heather A and Bruinenberg, Marcel and Caspersen, Ida H and Ida Chen, Yii-Der and Clarke, Robert and Warwick Daw, E and de Craen, Anton J. M and Delgado, Graciela and Dimitriou, Maria and ... and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GLGC and The GENIE Consortium and The AGEN-BMI Working Group and The MIGen Consortium and The MuTHER Consortium and The LifeLines Cohort Study and ADIPOGen Consortium and PAGE Consortium and LifeLines Cohort Study and MIGen Consortium and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and CKDGen Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and AGEN-BMI Working Grp and GLGC
Nature (London), ISSN 1476-4687, 2015, Volume 518, Issue 7538, pp. 197 - 206
Journal Article
Journal Article
Nature communications, ISSN 2041-1723, 2019, Volume 10, Issue 1, pp. 1260 - 11
Journal Article
Diabetologia, ISSN 0012-186X, 2/2018, Volume 61, Issue 2, pp. 369 - 380
Subcutaneous adipocyte hypertrophy is associated with insulin resistance and increased risk of type 2 diabetes, and predicts its future development independent... 
Human | Pathogenic mechanisms | Transcription factors | Human Physiology | Metabolic Diseases | Internal Medicine | Epigenetic regulation | Basic science | Medicine & Public Health | Insulin sensitivity and resistance | Adipose tissue differentiation | DNA methylation | Weight regulation and obesity | ADIPOCYTE LINEAGE | ZFP423 | TRANSCRIPTIONAL REPRESSION | INSULIN SENSITIVITY | PLURIPOTENT STEM-CELLS | WHITE ADIPOSE-TISSUE | SIGNALING PATHWAY | ENDOCRINOLOGY & METABOLISM | FAT | DIFFERENTIATION | NIH 3T3 Cells | Bone Morphogenetic Protein 4 - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Adipocytes - cytology | Diabetes Mellitus, Type 2 - metabolism | RNA, Messenger - metabolism | Bone Morphogenetic Protein 4 - metabolism | Obesity - genetics | Promoter Regions, Genetic - genetics | Adipogenesis - physiology | DNA-Binding Proteins - metabolism | Cell Differentiation - genetics | DNA Methylation - physiology | Adipogenesis - genetics | Cell Differentiation - physiology | Gene Expression Regulation - genetics | RNA, Messenger - genetics | Gene Expression Regulation - physiology | DNA Methylation - genetics | Transcription Factors - genetics | 3T3-L1 Cells | DNA-Binding Proteins - genetics | Obesity - metabolism | Transcription Factors - metabolism | Animals | Epigenesis, Genetic - genetics | Adipocytes - metabolism | Mice | Type 2 diabetes | Epigenetic inheritance | Obesity | Methyltransferases | Genes | Genetic research | Insulin resistance | DNA binding proteins | Methylation | Azacytidine | Bone morphogenetic protein 4 | Chromatin | Adipose tissue | Diabetes mellitus | Adipocytes | Insulin | Fibroblasts | Epigenetics | Nuclease | Peroxisome proliferator-activated receptors | Zinc finger proteins | Cell size | Deoxyribonucleic acid--DNA | Hypertrophy | Adipogenesis | DNA sequencing | CpG islands | Cell and Molecular Biology | Cell- och molekylärbiologi
Journal Article
Molecular genetics and genomics : MGG, ISSN 1617-4623, 2018, Volume 294, Issue 2, pp. 395 - 408
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2012, Volume 287, Issue 13, pp. 10355 - 10367
Hepatic stellate cells (HSCs) undergo myofibroblastic activation in liver fibrosis and regeneration. This phenotypic switch is mechanistically similar to... 
PREF-1 | HETEROGENEITY | ACTIVATION | RAT HEPATOCYTES | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | EXPERIMENTAL MELANOMA METASTASIS | ADIPOCYTE DIFFERENTIATION | RECEPTOR | ADIPOGENESIS | EXPRESSION | Liver - pathology | Rats, Wistar | Coculture Techniques | Cyclin-Dependent Kinase 4 - genetics | Hepatic Stellate Cells - metabolism | Epithelial-Mesenchymal Transition - drug effects | Hepatocytes - pathology | Male | Cyclin A - genetics | Hepatocytes - metabolism | Epithelial-Mesenchymal Transition - genetics | Wnt Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Wnt Proteins - genetics | Liver Cirrhosis - metabolism | Epigenesis, Genetic - drug effects | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Liver Cirrhosis - genetics | Hepatic Stellate Cells - pathology | PPAR gamma - genetics | Cell Line | Liver Regeneration | Mitogen-Activated Protein Kinase 3 - genetics | Membrane Proteins - genetics | Cyclin A - metabolism | Liver - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Rats | Nuclear Proteins - metabolism | Cyclin-Dependent Kinase 4 - metabolism | Chick Embryo | Nerve Tissue Proteins - genetics | PPAR gamma - biosynthesis | Antibodies - pharmacology | Nerve Tissue Proteins - metabolism | Proto-Oncogene Proteins c-akt | Animals | Wnt Signaling Pathway - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Wnt Signaling Pathway - genetics | Epigenesis, Genetic - genetics | Chickens | Liver Cirrhosis - pathology | Cell Proliferation - drug effects | Mice | Cyclin D - genetics | Cyclin D - metabolism | Wnt Signaling | Regeneration | Partial Hepatectomy | Epigenetics | Pparγ | Peroxisome Proliferator-activated Receptor (PPAR) | Pref-1 | Cell Biology | Adipogenesis | Wnt10b
Journal Article
BioMed research international, ISSN 2314-6141, 2015, Volume 2015, pp. 1 - 14
Journal Article