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Nature medicine, ISSN 1546-170X, 01/2016, Volume 22, Issue 3, pp. 312 - 318
Uncoupling protein 1 (UCP1) is highly expressed in brown adipose tissue, where it generates heat by uncoupling electron transport from ATP production. UCP1 is... 
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Cell Biology | Research & Experimental Medicine | Enkephalins - metabolism | Humans | Middle Aged | Ion Channels - genetics | Male | RNA, Messenger - metabolism | Enkephalins - genetics | Mitochondrial Proteins - metabolism | Diet, High-Fat | Iodide Peroxidase - metabolism | Adipocytes, Brown - transplantation | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Oxygen Consumption | Apoptosis Regulatory Proteins - metabolism | Protein Precursors - metabolism | Mice | Iodide Peroxidase - genetics | Blood Glucose - metabolism | Integrin beta1 - genetics | Adipocytes, White - metabolism | Glucose Intolerance - metabolism | Proprotein Convertase 1 - genetics | Adipocytes, Brown - metabolism | Homeostasis | Mitochondrial Proteins - genetics | DNA-Binding Proteins - metabolism | Polymerase Chain Reaction | Apoptosis Regulatory Proteins - genetics | Adult | Female | Capillaries | Glucose Tolerance Test | Protein Precursors - genetics | Proprotein Convertase 1 - metabolism | Cell Transplantation | Adipocytes, White - transplantation | DNA-Binding Proteins - genetics | Obesity - metabolism | Integrin beta1 - metabolism | Interleukin-33 - genetics | Animals | Ion Channels - metabolism | Receptor, Platelet-Derived Growth Factor alpha - genetics | Adipocytes - metabolism | Fluorescent Antibody Technique | Interleukin-33 - metabolism | Adipocytes - transplantation | Aged | Glucose Clamp Technique | Uncoupling Protein 1 | Neovascularization, Physiologic | Adipose tissues | Physiological aspects | Genetic aspects | Research | Index Medicus | cytokine | human adipocyte | glucose | progenitors | adipokine | capillary | adrenergic | thermogenic adipose tissue | implant
Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 09/2012, Volume 303, Issue 5, pp. 605 - 618
Apelin is an endogenous ligand for the angiotensin-like 1 receptor (APJ) and has beneficial effects against myocardial ischemia-reperfusion injury. Little is... 
Stromal cell-derived factor-1α/C-X-C chemokine receptor-4 | Vascular progenitor cell | Myocardial repair | c-kit | Jagged1/notch3 | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Apoptosis - drug effects | Receptors, Notch - metabolism | Cardiomegaly - pathology | Vascular Endothelial Growth Factor A - metabolism | Antigens, CD - metabolism | Peptides - metabolism | Time Factors | Serrate-Jagged Proteins | Antigens, Ly - metabolism | Myocardial Infarction - physiopathology | Proto-Oncogene Proteins c-akt - metabolism | Apelin | Disease Models, Animal | Jagged-1 Protein | Biomarkers - metabolism | Ventricular Function, Left - drug effects | Cardiomegaly - physiopathology | Cardiotonic Agents - pharmacology | Myocardial Infarction - metabolism | Receptors, CXCR4 - metabolism | Cell Movement - drug effects | Myocytes, Cardiac - pathology | Regeneration - drug effects | Cardiomegaly - prevention & control | Chemokine CXCL12 - metabolism | Myocytes, Cardiac - drug effects | Intercellular Signaling Peptides and Proteins - pharmacology | Fibrosis | Myocytes, Cardiac - metabolism | Stem Cells - pathology | Mice | Myocardial Infarction - genetics | Neovascularization, Physiologic - drug effects | Glycoproteins - metabolism | Proto-Oncogene Proteins c-kit - metabolism | Stem Cells - metabolism | Recovery of Function | Intercellular Signaling Peptides and Proteins - metabolism | Myocardial Infarction - pathology | Membrane Proteins - metabolism | Nitric Oxide Synthase Type III - metabolism | Calcium-Binding Proteins - metabolism | Mice, Inbred C57BL | Cells, Cultured | Adipokines | AC133 Antigen | Animals | Myocardial Infarction - drug therapy | Stem Cells - drug effects | Receptor, Notch3 | Physiological aspects | Care and treatment | Health aspects | Ligands (Biochemistry) | Heart attack | Heart | Angiogenesis | Phosphorylation | T cell receptors | Heart attacks | Rodents | Index Medicus | c-Kit | stromal cell-derived factor-1α | myocardial repair | vascular progenitor cell | notch3 | Integrative Cardiovascular Physiology and Pathophysiology | jagged1 | C-X-C chemokine receptor-4
Journal Article
Journal Article
Annals of the rheumatic diseases, ISSN 0003-4967, 06/2015, Volume 74, Issue 6, pp. 1102 - 1109
Objectives Prediction of radiographic progression (RP) in early rheumatoid arthritis (eRA) would be very useful for optimal choice among available therapies.... 
Life Sciences & Biomedicine | Rheumatology | Science & Technology | Hydroxychloroquine - therapeutic use | Multivariate Analysis | Prognosis | Foot Joints - diagnostic imaging | Humans | Leptin - metabolism | Antibodies, Monoclonal - therapeutic use | Male | Vascular Endothelial Growth Factor A - metabolism | Methotrexate - therapeutic use | Receptors, Tumor Necrosis Factor, Type I - metabolism | Arthritis, Rheumatoid - diagnostic imaging | Chitinase-3-Like Protein 1 | Arthritis, Rheumatoid - metabolism | Lectins - metabolism | C-Reactive Protein - metabolism | Infliximab | Arthritis, Rheumatoid - drug therapy | Hand Joints - diagnostic imaging | Female | Drug Therapy, Combination | Interleukin-6 - metabolism | Antirheumatic Agents - therapeutic use | Biomarkers - metabolism | Severity of Illness Index | Sulfasalazine - therapeutic use | Resistin - metabolism | Serum Amyloid A Protein - metabolism | Epidermal Growth Factor - metabolism | Logistic Models | Matrix Metalloproteinase 3 - metabolism | Treatment Outcome | Adipokines - metabolism | Disease Progression | Radiography | Matrix Metalloproteinase 1 - metabolism | Vascular Cell Adhesion Molecule-1 - metabolism | Clinical trials | Usage | Care and treatment | Rheumatoid arthritis | Risk factors | Index Medicus | Clinical and Epidemiological Research | Rheumatoid Arthritis | Cytokines | Anti-TNF | Disease Activity | Patient perspective | 1506 | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Reumatologi och inflammation
Journal Article
PloS one, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, pp. e35905 - e35905
Hematopoietic progenitor CD133(+)/c-kit(+) cells have been shown to be involved in myocardial healing following myocardial infarction (MI). Previously we... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Up-Regulation | Capillaries - pathology | Receptors, Notch - metabolism | Cardiomegaly - pathology | Angiopoietin-1 - metabolism | Antigens, CD - metabolism | Peptides - metabolism | Serrate-Jagged Proteins | Bone Marrow - metabolism | Myocardium - metabolism | Endomyocardial Fibrosis - complications | Myocardial Infarction - physiopathology | Capillaries - metabolism | Apelin | Jagged-1 Protein | Capillaries - physiopathology | Signal Transduction | Cardiomegaly - physiopathology | Myocardial Infarction - metabolism | Receptors, CXCR4 - metabolism | Chemokine CXCL12 - metabolism | Hematopoietic Stem Cells - cytology | Endomyocardial Fibrosis - metabolism | Mice | Diabetes Mellitus, Type 2 - pathology | Cardiomegaly - metabolism | Cell Movement | Actins - metabolism | Glycoproteins - metabolism | Diabetes Mellitus, Type 2 - metabolism | Proto-Oncogene Proteins c-kit - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Platelet Endothelial Cell Adhesion Molecule-1 - metabolism | Myocardial Infarction - pathology | Endomyocardial Fibrosis - pathology | Membrane Proteins - metabolism | Heart Function Tests | Diabetes Mellitus, Type 2 - complications | Calcium-Binding Proteins - metabolism | Myocardium - pathology | Adipokines | AC133 Antigen | Cardiomegaly - complications | Myocardial Infarction - complications | Animals | Diabetes Mellitus, Type 2 - physiopathology | Bone Marrow - pathology | Receptor, Notch3 | Endomyocardial Fibrosis - physiopathology | Apoptosis | Advertising executives | Vascular endothelial growth factor | Adenoviruses | Heart attack | Myocardial infarction | Heart | Diabetic retinopathy | Heart attacks | Angiopoietin | Recovery of function | Smooth muscle | Cardiovascular disease | Recruitment | Angiogenesis | Toxicology | Cell growth | Ischemia | Data recovery | Rodents | Bone marrow | Repair | Heart diseases | Immunoglobulins | Diabetes mellitus | Coronary artery | Muscles | Pharmacology | c-Kit protein | Hemopoiesis | Studies | Ostomy | Coronary vessels | Fibrosis | Stem cells | Myocardium | Infarction | Diabetes | Laboratory animals | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, pp. e86326 - e86326
Objectives: Intermittent hypoxia (IH), resulted from recurring episodes of upper airway obstruction, is the hallmark feature and the most important... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Tumor Necrosis Factor-alpha - metabolism | Leptin - metabolism | Oxidative Stress - physiology | Tumor Necrosis Factor-alpha - blood | Sleep Apnea, Obstructive - blood | Glucose Transporter Type 1 - metabolism | NF-kappa B - metabolism | Insulin - blood | Oxygen - metabolism | Adipokines - blood | Hypoxia - metabolism | Inflammation - metabolism | Leptin - blood | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Insulin Resistance - physiology | Interleukin-6 - blood | Adiponectin - metabolism | Models, Animal | Interleukin-6 - metabolism | Cytokines - metabolism | Rats | Adipokines - metabolism | Adiponectin - blood | Sleep Apnea, Obstructive - metabolism | Insulin - metabolism | Animals | Adipocytes - metabolism | Blood Glucose - metabolism | Type 2 diabetes | Interleukins | RNA | Blood sugar | Leptin | Insulin resistance | Sleep apnea syndromes | Inflammation | Oxidative stress | Animal models | Transcription | Interleukin | Sleep apnea | Hormones | Adipocytes | Glucose | Metabolic syndrome | Blood | Adiponectin | Interleukin 6 | Respiratory tract | Sleep disorders | Airway management | Apnea | Rodents | Tumor necrosis factor-TNF | Deoxyribonucleic acid--DNA | Binding | Hypoxia-inducible factors | Glucose transporter | Hypertension | Obesity | Medical research | NF-κB protein | Oxygen | Cytokines | Tumor necrosis factor-α | Insulin | Studies | Glucose tolerance | Intolerance | Hospitals | Sleep | Hypoxia | Diabetes | Respiration | Transporter | Endocrinology | Nuclear reactions | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article