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Nature, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 450 - 455
Adipose tissue is a major site of energy storage and has a role in the regulation of metabolism through the release of adipokines. Here we show that mice with... 
CELLS | EXTRACELLULAR VESICLES | RNA | METABOLISM | MEMBRANE-VESICLES | MICRORNA BIOGENESIS | MULTIDISCIPLINARY SCIENCES | EXOSOMES | HUMAN OBESITY | MICROVESICLES | DIFFERENTIATION | Adipose Tissue, White - transplantation | Adipose Tissue, Brown - secretion | 3' Untranslated Regions - genetics | Adipose Tissue, White - metabolism | Fibroblast Growth Factors - genetics | Exosomes - genetics | Male | MicroRNAs - metabolism | Adipose Tissue, White - secretion | Adipose Tissue - metabolism | Organ Specificity - genetics | Transcription, Genetic | Adipose Tissue - secretion | Glucose Tolerance Test | Ribonuclease III - genetics | Paracrine Communication | Liver - metabolism | RNA, Messenger - genetics | Gene Expression Regulation | Genes, Reporter - genetics | Adipokines - metabolism | Ribonuclease III - deficiency | Adipose Tissue, Brown - transplantation | Adipose Tissue, Brown - cytology | Animals | Fibroblast Growth Factors - blood | Models, Biological | Adipose Tissue, Brown - metabolism | Mice | MicroRNAs - blood | MicroRNAs - genetics | Adipose Tissue - transplantation | RNA sequencing | Physiological aspects | MicroRNA | Gene expression | Observations | Methods | Enzymes | Adipocytes | Metabolism | Rodents | MicroRNAs | Index Medicus | Obesity | Brown fat | Lipodystrophy | Tissue crosstalk | Exosomes | Metabolic syndrome | FGF21
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 40, pp. 14466 - 14471
Brown adipocytes and muscle and dorsal dermis descend from precursor cells in the dermomyotome, but the factors that regulate commitment to the brown adipose... 
Cell culture techniques | Cell lines | Stem cells | Brown adipocytes | Brown adipose tissue | Adipocytes | Embryonic cells | Embryonic stem cells | White adipocytes | Cellular differentiation | Beige adipocyte | ADIPOCYTES | MULTIDISCIPLINARY SCIENCES | MOUSE | beige adipocyte | SATELLITE CELLS | ADULT HUMANS | IDENTIFICATION | SKELETAL-MUSCLE | WHITE FAT | OBESITY | brown adipose tissue | IN-VIVO | ADIPOSE-TISSUE | Immunohistochemistry | Adipose Tissue - embryology | Oligonucleotide Array Sequence Analysis | Myogenic Regulatory Factor 5 - genetics | Adipose Tissue, White - embryology | Adipose Tissue - cytology | Adipose Tissue, White - metabolism | Adipocytes - cytology | Gene Expression Profiling | Green Fluorescent Proteins - genetics | Mice, 129 Strain | Embryo, Mammalian - metabolism | Adipose Tissue - metabolism | Adipose Tissue, White - cytology | Flow Cytometry | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gene Expression Regulation, Developmental | Myogenic Regulatory Factor 5 - metabolism | Adipose Tissue, Brown - embryology | Adipogenesis - genetics | Cell Lineage - genetics | Biomarkers - metabolism | Green Fluorescent Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Microscopy, Confocal | Adipose Tissue, Brown - cytology | Animals | Embryo, Mammalian - embryology | Embryo, Mammalian - cytology | Adipocytes - metabolism | Adipose Tissue, Brown - metabolism | Adipose tissues | RNA sequencing | Platelet-derived growth factor | Genetic research | Genetic aspects | Research | Health aspects | Genetic markers | Gene expression | Embryos | Cells | Index Medicus | Biological Sciences
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7716, pp. 102 - 106
Thermogenesis by brown and beige adipose tissue, which requires activation by external stimuli, can counter metabolic disease(1). Thermogenic respiration is... 
ENERGY-EXPENDITURE | NONSHIVERING THERMOGENESIS | METABOLISM | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIA | LACTATE | FAT | UCP1 | DYSFUNCTION | BROWN-ADIPOCYTES | DEFICIENCY | Metabolomics | Reactive Oxygen Species - metabolism | Adipose Tissue, White - metabolism | Adipocytes - enzymology | Male | Adipocytes - drug effects | Thermogenesis - physiology | Adipose Tissue, White - cytology | Oxidation-Reduction - drug effects | Female | Uncoupling Protein 1 - metabolism | Adipose Tissue, Brown - enzymology | Obesity - metabolism | Adipose Tissue, Brown - cytology | Animals | Succinic Acid - pharmacology | Succinic Acid - metabolism | Adipocytes - metabolism | Obesity - prevention & control | Adipose Tissue, White - enzymology | Succinate Dehydrogenase - metabolism | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | Thermogenesis - drug effects | Adipose Tissue, White - drug effects | Adipose tissues | Physiological aspects | Control | Thermogenesis | Succinates | Protein kinase A | Tricarboxylic acid cycle | Reactive oxygen species | Succinate dehydrogenase | Dehydrogenases | Adipose tissue | Body fat | Activation | Adipocytes | Kinases | Dehydrogenase | Accumulation | Proteins | Signal transduction | Energy | Metabolites | Rodents | Oxidation | Adipose tissue (brown) | Oxygen | AMP | Cyclic AMP | Pharmacology | Metabolism | Lipolysis | Glucose tolerance | Signaling | Hypotheses | External stimuli | Respiration | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7656, pp. 107 - 112
Menopause is associated with bone loss and enhanced visceral adiposity. A polyclonal antibody that targets the beta-subunit of the pituitary hormone... 
WHITE | OBESITY | ENERGY-EXPENDITURE | BROWN-FAT | OSTEOCLAST FORMATION | MULTIDISCIPLINARY SCIENCES | FOLLICLE-STIMULATING-HORMONE | RECEPTOR | BONE MASS | MENOPAUSAL TRANSITION | OVARIECTOMIZED MICE | Obesity - drug therapy | Receptors, FSH - genetics | Adipose Tissue, White - metabolism | Diet, High-Fat - adverse effects | Follicle Stimulating Hormone, beta Subunit - antagonists & inhibitors | Male | Osteoporosis - drug therapy | Adipocytes - drug effects | Uncoupling Protein 1 - biosynthesis | Adipose Tissue - metabolism | Antibodies - immunology | Female | Receptors, FSH - metabolism | Adiposity - drug effects | Ovariectomy | Mitochondria - metabolism | Mitochondria - drug effects | Receptors, FSH - antagonists & inhibitors | Haploinsufficiency | Antibodies - pharmacology | Animals | Oxygen Consumption - drug effects | Adipocytes - metabolism | Obesity - prevention & control | Follicle Stimulating Hormone, beta Subunit - immunology | Adipose Tissue, Beige - drug effects | Mice | Thermogenesis - drug effects | Adipose Tissue - drug effects | Adipose Tissue, Beige - metabolism | Adipose Tissue, White - drug effects | Adipose tissues | Physiological aspects | Physiological research | Follicle-stimulating hormone | Thermogenesis | Research | Adipose tissue | Body fat | Menopause | Adipocytes | Hormones | Density | Osteoporosis | Mitochondria | Biomedical materials | Biocompatibility | Bone loss | Adipose tissue (brown) | Binding | Obesity | Immunoglobulins | Pituitary hormones | Blocking | Metabolism | Bone mass | Pituitary | Bone | Index Medicus
Journal Article
Science, ISSN 0036-8075, 5/2010, Volume 328, Issue 5982, pp. 1158 - 1161
Obesity results from chronic energy surplus and excess lipid storage in white adipose tissue (WAT). In contrast brown adipose tissue (BAT) efficiently burns... 
Obesity | Messenger RNA | White adipose tissue | Thermogenesis | REPORTS | Homeostasis | Brown adipose tissue | Brown adipocytes | Lipids | Adipocytes | Progenitor cells | OBESITY | MULTIDISCIPLINARY SCIENCES | PRDM16 | FAT | PPAR-GAMMA | RECEPTOR | IDENTIFICATION | CELECOXIB | ADIPOSE-TISSUE | Body Weight | Male | Mesenchymal Stromal Cells - cytology | Cyclooxygenase 2 - genetics | Adipose Tissue, White - physiology | Dietary Fats - administration & dosage | Dioxoles - pharmacology | Female | Obesity - etiology | Adipose Tissue | Adipogenesis | Signal Transduction | Mice, Inbred C57BL | Oxygen Consumption | Adipose Tissue, Brown - physiology | Adrenergic beta-Agonists - pharmacology | Mice, Transgenic | Receptors, Adrenergic, beta-3 - metabolism | Gene Expression Regulation, Enzymologic | Adipose Tissue, Brown - cytology | Adipocytes, Brown - physiology | Animals | Norepinephrine - metabolism | Energy Metabolism | Obesity - prevention & control | Adipose Tissue, White - enzymology | Cyclooxygenase 2 - metabolism | Mice, Obese | Mice | Adipocytes, Brown - cytology | Adrenergic beta-3 Receptor Agonists | Prostaglandins - metabolism | Physiological aspects | Cyclooxygenases | Energy metabolism | Fat cells | Research | Bioenergetics | Enzymes | Body fat | Cellular biology | Gene expression | Rodents | Index Medicus | Adipose tissues | Expenditures | Burns | Recruitment
Journal Article
2006, ISBN 1402039352, vi, 169
1. Mesenchymal Stem Cell Engineering and Transplantation: An introduction -- F. Aerts, G. Wagemaker 2. Establishment and Transduction of primary human... 
Clinical & internal medicine | Biomedical engineering | Cell culture | Biomedical materials | Stem cells | Life Sciences | Animal Physiology | Hematology | Biomedicine general | Cell Biology | Transplant Surgery
Book
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2013, Volume 110, Issue 9, pp. 3223 - 3224
Expression of bone morphogenetic protein 4 (BMP4) in adipocytes of white adipose tissue (WAT) produces “white adipocytes” with characteristics of brown fat and... 
PNAS PLUS: AUTHOR SUMMARIES | Brown adipose tissue | Mitochondria | Metabolism | Adipocyte terminal differentiation | Adipocytes, Brown - metabolism | Bone Morphogenetic Protein 4 - genetics | Humans | Adipose Tissue, White - metabolism | Adipocytes, White - enzymology | Fatty Acid-Binding Proteins - metabolism | Bone Morphogenetic Protein 4 - metabolism | Mitochondria - ultrastructure | Thinness - metabolism | Thinness - pathology | Adipocytes, White - drug effects | Adipose Tissue, White - ultrastructure | Diet, High-Fat | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Adipose Tissue, Brown - ultrastructure | p38 Mitogen-Activated Protein Kinases - metabolism | Homeostasis - drug effects | Adipocytes, Brown - pathology | Insulin - pharmacology | Adipocytes, Brown - drug effects | Mice, Inbred C57BL | Mice, Transgenic | Mitochondria - metabolism | 3T3-L1 Cells | Activating Transcription Factor 2 - metabolism | Adipose Tissue, Brown - pathology | Gene Expression Regulation - drug effects | Organ Size - drug effects | Phenotype | Adipocytes, White - pathology | Animals | Oxygen Consumption - drug effects | Adipose Tissue, White - enzymology | Glucose - metabolism | Trans-Activators - metabolism | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | Transcription Factors | Adipose Tissue, White - drug effects | Energy Metabolism - drug effects | OBESITY | MULTIDISCIPLINARY SCIENCES | Proteins | Tissue | Rodents | Homeostasis | Glucose | Gene expression | Cells | Index Medicus | Biological Sciences | metabolism | PNAS Plus | adipocyte terminal differentiation | brown adipose tissue | mitochondria
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 11/2017, Volume 49, pp. 15 - 21
Journal Article