Journal of Immunology, ISSN 0022-1767, 07/2011, Volume 187, Issue 1, pp. 538 - 552
An abnormal neutrophil subset has been identified in the PBMC fractions from lupus patients. We have proposed that these low-density granulocytes (LDGs) play...
PLASMACYTOID DENDRITIC CELLS | RHEUMATOID-ARTHRITIS | ATHEROSCLEROTIC PLAQUES | SERINE PROTEASES | IMMUNE-RESPONSES | GENE-EXPRESSION | ANTIMICROBIAL PEPTIDES | IMMUNOLOGY | EXTRACELLULAR TRAPS | DISEASE-ACTIVITY | GRANULOPOIESIS SIGNATURES | Lupus Nephritis - pathology | Cell Line | Cytotoxicity Tests, Immunologic | Oligonucleotide Array Sequence Analysis | Humans | Neutrophils - immunology | Adjuvants, Immunologic - toxicity | Lupus Nephritis - immunology | Autoantigens - toxicity | Autoantigens - immunology | Lupus Erythematosus, Systemic - immunology | Endothelium, Vascular - pathology | Leukocyte Count | Lupus Erythematosus, Systemic - pathology | Neutrophils - metabolism | Endothelium, Vascular - immunology | Neutrophil Infiltration - immunology | Neutrophils - pathology
PLASMACYTOID DENDRITIC CELLS | RHEUMATOID-ARTHRITIS | ATHEROSCLEROTIC PLAQUES | SERINE PROTEASES | IMMUNE-RESPONSES | GENE-EXPRESSION | ANTIMICROBIAL PEPTIDES | IMMUNOLOGY | EXTRACELLULAR TRAPS | DISEASE-ACTIVITY | GRANULOPOIESIS SIGNATURES | Lupus Nephritis - pathology | Cell Line | Cytotoxicity Tests, Immunologic | Oligonucleotide Array Sequence Analysis | Humans | Neutrophils - immunology | Adjuvants, Immunologic - toxicity | Lupus Nephritis - immunology | Autoantigens - toxicity | Autoantigens - immunology | Lupus Erythematosus, Systemic - immunology | Endothelium, Vascular - pathology | Leukocyte Count | Lupus Erythematosus, Systemic - pathology | Neutrophils - metabolism | Endothelium, Vascular - immunology | Neutrophil Infiltration - immunology | Neutrophils - pathology
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2018, Volume 13, Issue 4, pp. e0191926 - e0191926
CTLA-4 and CD28 exemplify a co-inhibitory and co-stimulatory signaling axis that dynamically sculpts the interaction of antigen-specific T cells with...
UNTREATED MELANOMA | CYTOKINE RELEASE ASSAYS | LUNG-CANCER | IN-VITRO | MEDIATED CYTOTOXICITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | CTLA-4 | ANTITUMOR ACTIVITIES | NIVOLUMAB PLUS IPILIMUMAB | Antineoplastic Agents, Immunological - toxicity | Epitope Mapping | Adjuvants, Immunologic - pharmacology | Antineoplastic Agents, Immunological - pharmacokinetics | Cricetulus | Cancer Vaccines - pharmacology | Humans | Immunoglobulin G - toxicity | Macaca fascicularis | Antineoplastic Agents, Immunological - chemistry | T-Lymphocytes, Regulatory - immunology | Adjuvants, Immunologic - pharmacokinetics | Neoplasms - therapy | Immunity, Cellular - drug effects | Adjuvants, Immunologic - chemistry | Immunoglobulin G - pharmacology | CHO Cells | Amino Acid Sequence | Immunoglobulin G - chemistry | Cells, Cultured | Models, Molecular | Adjuvants, Immunologic - toxicity | CTLA-4 Antigen - immunology | Antineoplastic Agents, Immunological - pharmacology | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocyte Activation - drug effects | Neoplasms - immunology | Antibody Formation - drug effects | CTLA-4 Antigen - antagonists & inhibitors | Toxicology | Pharmacology, Experimental | Research | Immunoglobulin G | Analysis | CD86 antigen | PD-1 protein | Lung cancer | Antibodies | Biochemistry | Lymphocytes T | CD28 antigen | Immunity | CTLA-4 protein | Lymphocytes | Immunotherapy | Combined vaccines | Primates | Repressing | Medical research | Immunoglobulins | Cytokines | Immunoregulation | Immunomodulation | Research & development--R&D | CD80 antigen | Pharmacology | T cell receptors | Chemical compounds | Signaling | Antigen-presenting cells | Biomarkers | Index Medicus | Research & development | R&D
UNTREATED MELANOMA | CYTOKINE RELEASE ASSAYS | LUNG-CANCER | IN-VITRO | MEDIATED CYTOTOXICITY | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | REGULATORY T-CELLS | CTLA-4 | ANTITUMOR ACTIVITIES | NIVOLUMAB PLUS IPILIMUMAB | Antineoplastic Agents, Immunological - toxicity | Epitope Mapping | Adjuvants, Immunologic - pharmacology | Antineoplastic Agents, Immunological - pharmacokinetics | Cricetulus | Cancer Vaccines - pharmacology | Humans | Immunoglobulin G - toxicity | Macaca fascicularis | Antineoplastic Agents, Immunological - chemistry | T-Lymphocytes, Regulatory - immunology | Adjuvants, Immunologic - pharmacokinetics | Neoplasms - therapy | Immunity, Cellular - drug effects | Adjuvants, Immunologic - chemistry | Immunoglobulin G - pharmacology | CHO Cells | Amino Acid Sequence | Immunoglobulin G - chemistry | Cells, Cultured | Models, Molecular | Adjuvants, Immunologic - toxicity | CTLA-4 Antigen - immunology | Antineoplastic Agents, Immunological - pharmacology | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocyte Activation - drug effects | Neoplasms - immunology | Antibody Formation - drug effects | CTLA-4 Antigen - antagonists & inhibitors | Toxicology | Pharmacology, Experimental | Research | Immunoglobulin G | Analysis | CD86 antigen | PD-1 protein | Lung cancer | Antibodies | Biochemistry | Lymphocytes T | CD28 antigen | Immunity | CTLA-4 protein | Lymphocytes | Immunotherapy | Combined vaccines | Primates | Repressing | Medical research | Immunoglobulins | Cytokines | Immunoregulation | Immunomodulation | Research & development--R&D | CD80 antigen | Pharmacology | T cell receptors | Chemical compounds | Signaling | Antigen-presenting cells | Biomarkers | Index Medicus | Research & development | R&D
Journal Article
Science, ISSN 0036-8075, 6/2007, Volume 316, Issue 5831, pp. 1628 - 1632
The inflammatory toxicity of lipopolysaccharide (LPS), a component of bacterial cell walls, is driven by the adaptor proteins myeloid differentiation factor 88...
T lymphocytes | Spleen | Receptors | Immunization | Vaccine components | Vaccination | Antibodies | Agonists | Reports | Ova | Immunity | RESPONSES | CELLS | ACTIVATION | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | ENDOTOXIN | GENES | LIPOPOLYSACCHARIDE | TOLL | EXPRESSION | BETA | Adjuvants, Immunologic - administration & dosage | Oligonucleotide Array Sequence Analysis | Ovalbumin - immunology | Lipid A - analogs & derivatives | Monocytes - immunology | Phosphatidylinositol 3-Kinases - metabolism | Adoptive Transfer | Adaptor Proteins, Vesicular Transport - metabolism | Lipopolysaccharides - immunology | Lipid A - immunology | Toll-Like Receptor 4 - agonists | Macrophages - immunology | Lipid A - administration & dosage | Signal Transduction | Lymphocyte Activation | Mice, Inbred C57BL | Adjuvants, Immunologic - toxicity | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 4 - metabolism | Animals | Lipid A - toxicity | T-Lymphocytes - immunology | Mice | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Antimitotic agents | Bacterial cell walls | Research | Interleukins | Antineoplastic agents | Bacterial vaccines | Pharmacology | Immunology | Vaccines | Toxicity | Rodents
T lymphocytes | Spleen | Receptors | Immunization | Vaccine components | Vaccination | Antibodies | Agonists | Reports | Ova | Immunity | RESPONSES | CELLS | ACTIVATION | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | ENDOTOXIN | GENES | LIPOPOLYSACCHARIDE | TOLL | EXPRESSION | BETA | Adjuvants, Immunologic - administration & dosage | Oligonucleotide Array Sequence Analysis | Ovalbumin - immunology | Lipid A - analogs & derivatives | Monocytes - immunology | Phosphatidylinositol 3-Kinases - metabolism | Adoptive Transfer | Adaptor Proteins, Vesicular Transport - metabolism | Lipopolysaccharides - immunology | Lipid A - immunology | Toll-Like Receptor 4 - agonists | Macrophages - immunology | Lipid A - administration & dosage | Signal Transduction | Lymphocyte Activation | Mice, Inbred C57BL | Adjuvants, Immunologic - toxicity | Toll-Like Receptor 4 - immunology | Toll-Like Receptor 4 - metabolism | Animals | Lipid A - toxicity | T-Lymphocytes - immunology | Mice | Myeloid Differentiation Factor 88 - metabolism | Cytokines - biosynthesis | Antimitotic agents | Bacterial cell walls | Research | Interleukins | Antineoplastic agents | Bacterial vaccines | Pharmacology | Immunology | Vaccines | Toxicity | Rodents
Journal Article
Current Opinion in Pharmacology, ISSN 1471-4892, 08/2018, Volume 41, pp. 42 - 51
Most infections are caused by pathogens that access the body at mucosal sites. Hence, development of mucosal vaccines to prevent local infection or invasion of...
HEAT-LABILE ENTEROTOXIN | DENDRITIC CELLS | CHOLERA-TOXIN ADJUVANT | HELICOBACTER-PYLORI INFECTION | CTA1-DD ADJUVANT | PHARMACOLOGY & PHARMACY | INFLUENZA VACCINE | ESCHERICHIA-COLI ETEC | B-SUBUNIT | SYSTEMIC IMMUNE-RESPONSES | MUCOSAL ADJUVANT | Adjuvants, Immunologic - pharmacology | Enterotoxins - toxicity | Humans | Immunity, Mucosal | Bacterial Toxins - toxicity | Adjuvants, Immunologic - toxicity | ADP-Ribosylation | Cholera Toxin - toxicity | Bacterial Toxins - chemistry | Adjuvants, Immunologic - chemistry | Bacterial Toxins - pharmacology | Escherichia coli Proteins - pharmacology | Cholera Toxin - chemistry | Cholera Toxin - pharmacology | Escherichia coli Proteins - toxicity | Enterotoxins - chemistry | Escherichia coli Proteins - chemistry | Enterotoxins - pharmacology | Vaccines | Cholera toxin | Gene mutations | T cells | Adenosine triphosphatase | interleukin 12 | CD40 antigen | lymphocyte differentiation | Escherichia coli | interleukin 17 | guanine nucleotide binding protein | Th2 cell | chemokine receptor CCR4 | B7 antigen | STAT3 protein | interleukin 6 | interleukin 5 | interleukin 4 | conformational transition | endoplasmic reticulum associated degradation | enzyme activity | upregulation | cyclic AMP | endocytosis | protein expression | interleukin 10 | protein protein interaction | enterotoxin | protein cleavage | CXCL13 chemokine | chemokine receptor CCR7 | nonhuman | unclassified drug | humoral immunity | gamma interferon | CD86 antigen | Th17 cell | major histocompatibility antigen class 2 | Vibrio cholerae | Immunologi inom det medicinska området | Review | immunological adjuvant | enzyme conformation | disulfide bond | cyclic AMP responsive element binding protein | ganglioside GM1 | priority journal | Immunology in the medical area | interleukin 23 | adenosine diphosphate ribosylation factor 6 | nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase | cellular immunity | protein binding | interferon consensus sequence binding protein | nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase A1 | nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase A2 | cystic fibrosis transmembrane conductance regulator | adenosine diphosphate ribosylation | Th1 cell | endoplasmic reticulum
HEAT-LABILE ENTEROTOXIN | DENDRITIC CELLS | CHOLERA-TOXIN ADJUVANT | HELICOBACTER-PYLORI INFECTION | CTA1-DD ADJUVANT | PHARMACOLOGY & PHARMACY | INFLUENZA VACCINE | ESCHERICHIA-COLI ETEC | B-SUBUNIT | SYSTEMIC IMMUNE-RESPONSES | MUCOSAL ADJUVANT | Adjuvants, Immunologic - pharmacology | Enterotoxins - toxicity | Humans | Immunity, Mucosal | Bacterial Toxins - toxicity | Adjuvants, Immunologic - toxicity | ADP-Ribosylation | Cholera Toxin - toxicity | Bacterial Toxins - chemistry | Adjuvants, Immunologic - chemistry | Bacterial Toxins - pharmacology | Escherichia coli Proteins - pharmacology | Cholera Toxin - chemistry | Cholera Toxin - pharmacology | Escherichia coli Proteins - toxicity | Enterotoxins - chemistry | Escherichia coli Proteins - chemistry | Enterotoxins - pharmacology | Vaccines | Cholera toxin | Gene mutations | T cells | Adenosine triphosphatase | interleukin 12 | CD40 antigen | lymphocyte differentiation | Escherichia coli | interleukin 17 | guanine nucleotide binding protein | Th2 cell | chemokine receptor CCR4 | B7 antigen | STAT3 protein | interleukin 6 | interleukin 5 | interleukin 4 | conformational transition | endoplasmic reticulum associated degradation | enzyme activity | upregulation | cyclic AMP | endocytosis | protein expression | interleukin 10 | protein protein interaction | enterotoxin | protein cleavage | CXCL13 chemokine | chemokine receptor CCR7 | nonhuman | unclassified drug | humoral immunity | gamma interferon | CD86 antigen | Th17 cell | major histocompatibility antigen class 2 | Vibrio cholerae | Immunologi inom det medicinska området | Review | immunological adjuvant | enzyme conformation | disulfide bond | cyclic AMP responsive element binding protein | ganglioside GM1 | priority journal | Immunology in the medical area | interleukin 23 | adenosine diphosphate ribosylation factor 6 | nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase | cellular immunity | protein binding | interferon consensus sequence binding protein | nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase A1 | nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase A2 | cystic fibrosis transmembrane conductance regulator | adenosine diphosphate ribosylation | Th1 cell | endoplasmic reticulum
Journal Article
5.
Full Text
Single-Walled and Multi-Walled Carbon Nanotubes Promote Allergic Immune Responses in Mice
Toxicological Sciences, ISSN 1096-6080, 5/2009, Volume 109, Issue 1, pp. 113 - 123
The adjuvant effect of particles on allergic immune responses has been shown to increase with decreasing particle size and increasing particle surface area....
Carbon nanotubes | Allergy | Mice | Adjuvant effect | Airway inflammation | IgE | airway inflammation | adjuvant effect | DIESEL EXHAUST PARTICLES | IGE PRODUCTION | ADJUVANT ACTIVITY | allergy | TOXICITY | mice | carbon nanotubes | SENSITIZATION | ULTRAFINE PARTICLES | FINE PARTICLES | TOXICOLOGY | RESPIRATORY HEALTH | ANTIGEN | Inflammation - chemically induced | Immunoglobulin G - blood | Ovalbumin - immunology | Cytokines - analysis | Soot - toxicity | Nanotubes, Carbon - ultrastructure | Adjuvants, Immunologic - toxicity | Lymph Nodes - immunology | Microscopy, Electron | Administration, Intranasal | Immunoglobulin E - blood | Animals | Nanotubes, Carbon - toxicity | Analysis of Variance | Hypersensitivity - etiology | Injections, Subcutaneous | Female | Bronchoalveolar Lavage Fluid - cytology | Mice, Inbred BALB C | Bronchoalveolar Lavage Fluid - chemistry | Index Medicus
Carbon nanotubes | Allergy | Mice | Adjuvant effect | Airway inflammation | IgE | airway inflammation | adjuvant effect | DIESEL EXHAUST PARTICLES | IGE PRODUCTION | ADJUVANT ACTIVITY | allergy | TOXICITY | mice | carbon nanotubes | SENSITIZATION | ULTRAFINE PARTICLES | FINE PARTICLES | TOXICOLOGY | RESPIRATORY HEALTH | ANTIGEN | Inflammation - chemically induced | Immunoglobulin G - blood | Ovalbumin - immunology | Cytokines - analysis | Soot - toxicity | Nanotubes, Carbon - ultrastructure | Adjuvants, Immunologic - toxicity | Lymph Nodes - immunology | Microscopy, Electron | Administration, Intranasal | Immunoglobulin E - blood | Animals | Nanotubes, Carbon - toxicity | Analysis of Variance | Hypersensitivity - etiology | Injections, Subcutaneous | Female | Bronchoalveolar Lavage Fluid - cytology | Mice, Inbred BALB C | Bronchoalveolar Lavage Fluid - chemistry | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 07/2015, Volume 6, Issue 1, p. 7687
Accumulating epidemiologic evidence has revealed that metabolic syndrome is an independent risk factor for psoriasis development and is associated with more...
Dermatitis - immunology | Imiquimod | Humans | Middle Aged | Interleukin-17 - immunology | Receptors, Adiponectin - immunology | Aminoquinolines - toxicity | Immunoblotting | Male | CD4-Positive T-Lymphocytes - immunology | Adiponectin - genetics | Subcutaneous Fat | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Real-Time Polymerase Chain Reaction | Skin - immunology | Psoriasis - immunology | Interleukin-23 - toxicity | CD4-Positive T-Lymphocytes - metabolism | Receptors, Antigen, T-Cell, gamma-delta - immunology | Adjuvants, Immunologic - toxicity | Reverse Transcriptase Polymerase Chain Reaction | Dermatitis - etiology | Interleukin-17 - metabolism | Animals | Mice | Adiponectin - immunology | CD8-Positive T-Lymphocytes - immunology
Dermatitis - immunology | Imiquimod | Humans | Middle Aged | Interleukin-17 - immunology | Receptors, Adiponectin - immunology | Aminoquinolines - toxicity | Immunoblotting | Male | CD4-Positive T-Lymphocytes - immunology | Adiponectin - genetics | Subcutaneous Fat | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Real-Time Polymerase Chain Reaction | Skin - immunology | Psoriasis - immunology | Interleukin-23 - toxicity | CD4-Positive T-Lymphocytes - metabolism | Receptors, Antigen, T-Cell, gamma-delta - immunology | Adjuvants, Immunologic - toxicity | Reverse Transcriptase Polymerase Chain Reaction | Dermatitis - etiology | Interleukin-17 - metabolism | Animals | Mice | Adiponectin - immunology | CD8-Positive T-Lymphocytes - immunology
Journal Article
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 10/2018, Volume 131, pp. 33 - 43
The development of new vaccine adjuvants is urgently needed not only to enable new routes of vaccine administration but mostly to go beyond protective humoral...
β-glucan | HBsAg | Vaccine adjuvants | Chitosan | Polymeric particles | CELLS | ACTIVATION | beta-glucan | DECTIN-1 | NANOPARTICLES | INFECTIOUS-DISEASES | IMMUNE-RESPONSES | PHARMACOLOGY & PHARMACY | SURFACE-ANTIGEN | DRUG-DELIVERY SYSTEMS | INNATE IMMUNITY | Adjuvants, Immunologic - pharmacology | Humans | beta-Glucans - chemistry | Nanoparticles | Hepatitis B Vaccines - toxicity | Adjuvants, Immunologic - chemistry | Immunoglobulin G - immunology | Chitosan - pharmacology | Female | Cell Survival - drug effects | Cross-Linking Reagents | Hepatitis B Vaccines - chemistry | Mice, Inbred C57BL | Hepatitis B Surface Antigens - immunology | Adjuvants, Immunologic - toxicity | beta-Glucans - pharmacology | Chitosan - toxicity | Hepatitis B Antigens | Hepatitis B Surface Antigens - toxicity | Particle Size | Macrophages - metabolism | Animals | Chitosan - chemistry | beta-Glucans - toxicity | RAW 264.7 Cells | Hepatitis B Surface Antigens - drug effects | Hepatitis B Vaccines - immunology | Mice | Interferon-gamma - biosynthesis
β-glucan | HBsAg | Vaccine adjuvants | Chitosan | Polymeric particles | CELLS | ACTIVATION | beta-glucan | DECTIN-1 | NANOPARTICLES | INFECTIOUS-DISEASES | IMMUNE-RESPONSES | PHARMACOLOGY & PHARMACY | SURFACE-ANTIGEN | DRUG-DELIVERY SYSTEMS | INNATE IMMUNITY | Adjuvants, Immunologic - pharmacology | Humans | beta-Glucans - chemistry | Nanoparticles | Hepatitis B Vaccines - toxicity | Adjuvants, Immunologic - chemistry | Immunoglobulin G - immunology | Chitosan - pharmacology | Female | Cell Survival - drug effects | Cross-Linking Reagents | Hepatitis B Vaccines - chemistry | Mice, Inbred C57BL | Hepatitis B Surface Antigens - immunology | Adjuvants, Immunologic - toxicity | beta-Glucans - pharmacology | Chitosan - toxicity | Hepatitis B Antigens | Hepatitis B Surface Antigens - toxicity | Particle Size | Macrophages - metabolism | Animals | Chitosan - chemistry | beta-Glucans - toxicity | RAW 264.7 Cells | Hepatitis B Surface Antigens - drug effects | Hepatitis B Vaccines - immunology | Mice | Interferon-gamma - biosynthesis
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 05/2016, Volume 299, pp. 70 - 77
Nanoparticle immunogenicity and antigenicity have been under investigation for many years. During the past decade, significant progress has been made in...
Nanoparticles | Anaphylaxis | Immunogenicity | Cytokines | Antigenicity | Antibody | Preclinical | Phagocytosis | ANTI-PEG ANTIBODIES | COMPLEMENT ACTIVATION | ABC PHENOMENON | REPEATED INJECTIONS | MONOCLONAL-ANTIBODY | HETEROGENEOUS NUCLEATION | ACCELERATED BLOOD CLEARANCE | PEGYLATED LIPOSOMES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | POLYETHYLENE-GLYCOL | IMMUNOLOGICAL-PROPERTIES | Immunogenetic Phenomena - drug effects | Adjuvants, Immunologic - administration & dosage | Humans | Drug Carriers - administration & dosage | Drug Carriers - toxicity | Adjuvants, Immunologic - toxicity | Comprehension | Immunogenetic Phenomena - immunology | Forecasting | Immunity, Cellular - immunology | Animals | Immunity, Cellular - drug effects | Nanostructures - administration & dosage | Antigenic Modulation - drug effects | Antigenic Modulation - immunology | Nanostructures - toxicity | Drug Delivery Systems - methods | Drug Delivery Systems - adverse effects | Biological products | Drugs | Viral antibodies | Medical research | Drug delivery systems | Immune response | Medicine, Experimental | Antibodies | T cells | Nanotechnology | Vehicles | Index Medicus | ANTIBODIES | BIOTECHNOLOGY | REVIEWS | ENGINEERS | PARTICULATES | NANOMATERIALS | 60 APPLIED LIFE SCIENCES | CARRIERS | NANOPARTICLES | LYMPHOKINES | ANTIBODY FORMATION | ANAPHYLAXIS | DRUG DELIVERY
Nanoparticles | Anaphylaxis | Immunogenicity | Cytokines | Antigenicity | Antibody | Preclinical | Phagocytosis | ANTI-PEG ANTIBODIES | COMPLEMENT ACTIVATION | ABC PHENOMENON | REPEATED INJECTIONS | MONOCLONAL-ANTIBODY | HETEROGENEOUS NUCLEATION | ACCELERATED BLOOD CLEARANCE | PEGYLATED LIPOSOMES | PHARMACOLOGY & PHARMACY | TOXICOLOGY | POLYETHYLENE-GLYCOL | IMMUNOLOGICAL-PROPERTIES | Immunogenetic Phenomena - drug effects | Adjuvants, Immunologic - administration & dosage | Humans | Drug Carriers - administration & dosage | Drug Carriers - toxicity | Adjuvants, Immunologic - toxicity | Comprehension | Immunogenetic Phenomena - immunology | Forecasting | Immunity, Cellular - immunology | Animals | Immunity, Cellular - drug effects | Nanostructures - administration & dosage | Antigenic Modulation - drug effects | Antigenic Modulation - immunology | Nanostructures - toxicity | Drug Delivery Systems - methods | Drug Delivery Systems - adverse effects | Biological products | Drugs | Viral antibodies | Medical research | Drug delivery systems | Immune response | Medicine, Experimental | Antibodies | T cells | Nanotechnology | Vehicles | Index Medicus | ANTIBODIES | BIOTECHNOLOGY | REVIEWS | ENGINEERS | PARTICULATES | NANOMATERIALS | 60 APPLIED LIFE SCIENCES | CARRIERS | NANOPARTICLES | LYMPHOKINES | ANTIBODY FORMATION | ANAPHYLAXIS | DRUG DELIVERY
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 2009, Volume 138, Issue 2, pp. 113 - 121
For oral vaccination, incorporation of antigens into nanoparticles has been shown to protect the antigen from degradation, but may also increase its uptake...
Nanoparticles | Oral vaccine | Chitosan | Trimethyl-chitosan | M-cells | Nanoparticles - chemistry | Serum Albumin, Bovine - administration & dosage | Biocompatible Materials - chemistry | Dendritic Cells - immunology | Humans | Vaccines - pharmacokinetics | Drug Carriers - toxicity | Peyer's Patches - drug effects | Biocompatible Materials - toxicity | Drug Carriers - chemistry | Intestinal Mucosa - drug effects | Immunity, Mucosal - drug effects | Adjuvants, Immunologic - chemistry | Intestinal Mucosa - immunology | Surface Properties | Drug Compounding | Dendritic Cells - drug effects | Female | Caco-2 Cells | Duodenum - immunology | Cell Survival - drug effects | Vaccines - immunology | Adjuvants, Immunologic - toxicity | Nanoparticles - toxicity | Particle Size | Serum Albumin, Bovine - pharmacokinetics | Animals | Chitosan - chemistry | Mice | Mice, Inbred BALB C | Peyer's Patches - immunology | Vaccines - administration & dosage | Duodenum - drug effects | IMMUNE-RESPONSE | DENDRITIC CELLS | VIVO | MICROPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | TRIMETHYL CHITOSAN NANOPARTICLES | DELIVERY | MURINE | IMMUNIZATION | IN-VITRO | PHARMACOLOGY & PHARMACY | BIOMATERIALS | Drugs | Antigens | Drug delivery systems | Dendritic cells | Analysis | Pharmacy | Vaccination | Albumin | Vehicles | tripolyphosphate | Flow cytometry | Ovalbumin | chitosan | Immune response | Biodegradability | Gelation | Mucosa | Oral administration | Antibodies | Adjuvants | Confocal microscopy | Epithelium | Follicles | Monocytes | nanoparticles | Intestine | polylactide-co-glycolide | Controlled release
Nanoparticles | Oral vaccine | Chitosan | Trimethyl-chitosan | M-cells | Nanoparticles - chemistry | Serum Albumin, Bovine - administration & dosage | Biocompatible Materials - chemistry | Dendritic Cells - immunology | Humans | Vaccines - pharmacokinetics | Drug Carriers - toxicity | Peyer's Patches - drug effects | Biocompatible Materials - toxicity | Drug Carriers - chemistry | Intestinal Mucosa - drug effects | Immunity, Mucosal - drug effects | Adjuvants, Immunologic - chemistry | Intestinal Mucosa - immunology | Surface Properties | Drug Compounding | Dendritic Cells - drug effects | Female | Caco-2 Cells | Duodenum - immunology | Cell Survival - drug effects | Vaccines - immunology | Adjuvants, Immunologic - toxicity | Nanoparticles - toxicity | Particle Size | Serum Albumin, Bovine - pharmacokinetics | Animals | Chitosan - chemistry | Mice | Mice, Inbred BALB C | Peyer's Patches - immunology | Vaccines - administration & dosage | Duodenum - drug effects | IMMUNE-RESPONSE | DENDRITIC CELLS | VIVO | MICROPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | TRIMETHYL CHITOSAN NANOPARTICLES | DELIVERY | MURINE | IMMUNIZATION | IN-VITRO | PHARMACOLOGY & PHARMACY | BIOMATERIALS | Drugs | Antigens | Drug delivery systems | Dendritic cells | Analysis | Pharmacy | Vaccination | Albumin | Vehicles | tripolyphosphate | Flow cytometry | Ovalbumin | chitosan | Immune response | Biodegradability | Gelation | Mucosa | Oral administration | Antibodies | Adjuvants | Confocal microscopy | Epithelium | Follicles | Monocytes | nanoparticles | Intestine | polylactide-co-glycolide | Controlled release
Journal Article
Journal of Immunology, ISSN 0022-1767, 09/2010, Volume 185, Issue 6, pp. 3677 - 3684
B7-H3, a new member of the B7 superfamily, acts as both a T cell costimulator and coinhibitor, and thus plays a key role in the regulation of T cell-mediated...
IMMUNITY | ACTIVATION | DENDRITIC CELLS | RECOGNITION | IN-VIVO | ENHANCEMENT | MONOCYTES | IMMUNOLOGY | T-CELLS | FAMILY | MOLECULES | Receptors, Immunologic - physiology | Humans | Tumor Necrosis Factor-alpha - blood | Adjuvants, Immunologic - blood | Male | Monocytes - immunology | Macrophages - secretion | Sepsis - pathology | Bacterial Outer Membrane Proteins - toxicity | Interleukin-6 - blood | Monocytes - pathology | Inflammation Mediators - physiology | Macrophages - immunology | Receptors, Immunologic - blood | Monocytes - secretion | Cell Line | Adjuvants, Immunologic - physiology | Sepsis - immunology | Lipopolysaccharides - toxicity | Macrophages - pathology | Cells, Cultured | Inflammation Mediators - blood | Inflammation Mediators - toxicity | B7-1 Antigen - physiology | Adjuvants, Immunologic - toxicity | Immunity, Innate | Mice, Inbred C3H | Sepsis - mortality | Toll-Like Receptor 4 - physiology | Antigens, CD - blood | Animals | Toll-Like Receptor 2 - physiology | Antigens, CD - physiology | Mice | Sepsis - microbiology | B7 Antigens
IMMUNITY | ACTIVATION | DENDRITIC CELLS | RECOGNITION | IN-VIVO | ENHANCEMENT | MONOCYTES | IMMUNOLOGY | T-CELLS | FAMILY | MOLECULES | Receptors, Immunologic - physiology | Humans | Tumor Necrosis Factor-alpha - blood | Adjuvants, Immunologic - blood | Male | Monocytes - immunology | Macrophages - secretion | Sepsis - pathology | Bacterial Outer Membrane Proteins - toxicity | Interleukin-6 - blood | Monocytes - pathology | Inflammation Mediators - physiology | Macrophages - immunology | Receptors, Immunologic - blood | Monocytes - secretion | Cell Line | Adjuvants, Immunologic - physiology | Sepsis - immunology | Lipopolysaccharides - toxicity | Macrophages - pathology | Cells, Cultured | Inflammation Mediators - blood | Inflammation Mediators - toxicity | B7-1 Antigen - physiology | Adjuvants, Immunologic - toxicity | Immunity, Innate | Mice, Inbred C3H | Sepsis - mortality | Toll-Like Receptor 4 - physiology | Antigens, CD - blood | Animals | Toll-Like Receptor 2 - physiology | Antigens, CD - physiology | Mice | Sepsis - microbiology | B7 Antigens
Journal Article