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Brain, Behavior, and Immunity, ISSN 0889-1591, 2014, Volume 41, Issue 1, pp. 90 - 100
Abstract Depression is an inflammatory disorder. Pro-inflammatory cytokine interleukin-1 beta (IL-1β) may play a pivotal role in the central nervous system... 
Psychiatry | Allergy and Immunology | Depression | IL-1β-related CNS inflammation | Chronic unpredictable mild stress | Prefrontal cortex | NLRP3 inflammasome | ANTIDEPRESSANT | CHRONIC MILD STRESS | CYTOKINE LEVELS | MAJOR DEPRESSION | IMMUNOLOGY | IL-1 beta-related CNS inflammation | FLUOXETINE | NEUROSCIENCES | TOLL-LIKE | DISORDER | ALTERED EXPRESSION | PITUITARY-ADRENAL AXIS | BRAIN | Microglia - metabolism | Rats, Wistar | Sucrose | Depressive Disorder - pathology | NLR Family, Pyrin Domain-Containing 3 Protein | Nerve Tissue Proteins - analysis | Stress, Physiological | Depressive Disorder - drug therapy | Male | NF-kappa B - metabolism | Receptors, Cytoplasmic and Nuclear - biosynthesis | Interleukin-1beta - blood | Prefrontal Cortex - pathology | Nerve Tissue Proteins - biosynthesis | Microglia - pathology | Interleukin-1beta - biosynthesis | Fluoxetine - therapeutic use | Carrier Proteins | Interleukin-1beta - physiology | Nerve Tissue Proteins - physiology | Calcium-Binding Proteins - analysis | Gene Expression Regulation | Interleukin-1beta - cerebrospinal fluid | Microfilament Proteins - analysis | Rats | Anhedonia | Receptors, Cytoplasmic and Nuclear - physiology | Inflammation | Random Allocation | Depressive Disorder - metabolism | Drinking Behavior | Antidepressive Agents - therapeutic use | Inflammasomes - physiology | Animals | Receptors, Cytoplasmic and Nuclear - analysis | Prefrontal Cortex - metabolism | Enzyme Activation | Chronic Disease
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