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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 09/2011, Volume 184, Issue 5, pp. 561 - 568
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 06/2011, Volume 337, Issue 3, pp. 600 - 609
beta(2)-Adrenoceptor (beta(2)-AR) agonists are powerful bronchodilators and play a pivotal role in the management of pulmonary obstructive diseases, such as... 
BETA-ADRENOCEPTOR AGONISTS | FORMOTEROL | OBSTRUCTIVE PULMONARY-DISEASE | ASTHMA | PHARMACOLOGY & PHARMACY | BETA-2-ADRENOCEPTOR AGONIST | SELECTIVITY | BURDEN | BETA-ADRENERGIC RECEPTOR | SALMETEROL | COPD | Adrenergic beta-2 Receptor Agonists - pharmacokinetics | Ethanolamines - pharmacology | Formoterol Fumarate | Bronchodilator Agents - administration & dosage | Albuterol - pharmacology | Humans | Half-Life | Pulmonary Disease, Chronic Obstructive - physiopathology | Ethanolamines - administration & dosage | Adrenergic beta-2 Receptor Agonists - pharmacology | Bronchodilator Agents - chemistry | Ethanolamines - pharmacokinetics | Benzoxazines - pharmacokinetics | Albuterol - administration & dosage | Binding Sites | Benzoxazines - chemistry | Cricetinae | Salmeterol Xinafoate | Benzoxazines - administration & dosage | Adrenergic beta-2 Receptor Agonists - chemistry | Administration, Inhalation | Albuterol - analogs & derivatives | Albuterol - pharmacokinetics | Bronchodilator Agents - pharmacology | Receptors, Adrenergic, beta-1 - metabolism | Ethanolamines - chemistry | Asthma - drug therapy | Receptors, Adrenergic, beta-2 - metabolism | Animals | Bronchodilator Agents - pharmacokinetics | Benzoxazines - pharmacology | Adrenergic beta-2 Receptor Agonists - administration & dosage | Albuterol - chemistry | Mice | Mice, Inbred BALB C | Lipid Bilayers - metabolism | Pulmonary Disease, Chronic Obstructive - drug therapy
Journal Article
Journal Article
Molecular Pharmaceutics, ISSN 1543-8384, 08/2015, Volume 12, Issue 8, pp. 2633 - 2641
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e50716
Umeclidinium bromide (GSK573719; UMEC), a new long-acting muscarinic receptor antagonist (LAMA), is in development with vilanterol (GW642444; VI), a selective... 
Adrenergic beta-2 Receptor Agonists - pharmacokinetics | Humans | Middle Aged | Muscarinic Antagonists - adverse effects | Benzyl Alcohols - administration & dosage | Benzyl Alcohols - adverse effects | Male | Quinuclidines - administration & dosage | Adrenergic beta-2 Receptor Agonists - pharmacology | Chlorobenzenes - administration & dosage | Young Adult | Chlorobenzenes - pharmacokinetics | Drug Interactions | Adrenergic beta-2 Receptor Agonists - adverse effects | Dry Powder Inhalers - instrumentation | Muscarinic Antagonists - pharmacology | Benzyl Alcohols - pharmacology | Chlorobenzenes - pharmacology | Patient Safety | Adult | Muscarinic Antagonists - pharmacokinetics | Benzyl Alcohols - pharmacokinetics | Drug Therapy, Combination | Quinuclidines - adverse effects | Double-Blind Method | Quinuclidines - pharmacology | Cross-Over Studies | Muscarinic Antagonists - administration & dosage | Chlorobenzenes - adverse effects | Adrenergic beta-2 Receptor Agonists - administration & dosage | Aged | Quinuclidines - pharmacokinetics | Medicine, Experimental | Medical research | Respiratory agents | Lung diseases, Obstructive | Care and treatment | Heart beat | Health care | Drugs | Pharmacodynamics | Acetylcholine receptors (muscarinic) | Laboratories | Medical treatment | Lung diseases | Systematic review | Pharmacology | Vital signs | Assessments | Powder | Heart rate | Human subjects | Studies | Obstructive lung disease | Chronic obstructive pulmonary disease | Blood pressure | Safety | Pharmacokinetics | Potassium | Drug dosages
Journal Article
Drugs, ISSN 0012-6667, 1/2016, Volume 76, Issue 1, pp. 135 - 146
Journal Article
Talanta, ISSN 0039-9140, 01/2013, Volume 104, pp. 97 - 102
Journal Article
Journal Article
Journal Article
Drug Delivery, ISSN 1071-7544, 01/2018, Volume 25, Issue 1, pp. 838 - 845
Treatment of respiratory disease with a drug delivered via inhalation is generally held as being beneficial as it provides direct access to the lung target... 
pharmacokinetics | mass spectrometry imaging | inhalation | Pulmonary distribution | lung retention | Lung retention | Pharmacokinetics | Mass spectrometry imaging | Inhalation | PULMONARY DRUG-DELIVERY | ROUTE | PHARMACOKINETIC/PHARMACODYNAMIC RELATIONSHIPS | PHOSPHOLIPIDS | RECEPTOR | AEROSOLIZED MEDICATIONS | MASS-SPECTROMETRY | METHODOLOGY | THERAPEUTIC EFFECTIVENESS | PHARMACOLOGY & PHARMACY | Adrenergic beta-2 Receptor Agonists - pharmacokinetics | Deuterium | Injections, Intravenous | Respiratory Mucosa - drug effects | Bronchodilator Agents - administration & dosage | Polysorbates - chemistry | Rats, Wistar | Salmeterol Xinafoate - metabolism | Salmeterol Xinafoate - pharmacokinetics | Male | Molecular Imaging | Polyethylene Glycols - chemistry | Lung - diagnostic imaging | Lung - cytology | Bronchodilator Agents - metabolism | Adrenergic beta-2 Receptor Agonists - pharmacology | Bronchi - drug effects | Tissue Distribution | Pharmaceutical Vehicles - chemistry | Mass Spectrometry | Pulmonary Alveoli - metabolism | Pulmonary Alveoli - cytology | Bronchi - metabolism | Pulmonary Alveoli - drug effects | Lung - metabolism | Pulmonary Alveoli - diagnostic imaging | Bronchi - cytology | Bronchi - diagnostic imaging | Respiratory Mucosa - cytology | Administration, Inhalation | Adrenergic beta-2 Receptor Agonists - metabolism | Bronchodilator Agents - pharmacology | Salmeterol Xinafoate - administration & dosage | Respiratory Tract Absorption | Salmeterol Xinafoate - pharmacology | Animals | Bronchodilator Agents - pharmacokinetics | Lung - drug effects | Adrenergic beta-2 Receptor Agonists - administration & dosage | Respiratory Mucosa - metabolism | Phosphatidylethanolamines - chemistry | Respiratory Mucosa - diagnostic imaging | Cluster Analysis | Retention | Localization | Respiratory diseases | Index Medicus | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Klinisk medicin | Clinical Medicine | Medicinska och farmaceutiska grundvetenskaper | Farmakologi och toxikologi | Lungmedicin och allergi | Pharmacology and Toxicology | Respiratory Medicine and Allergy
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 11/2015, Volume 25, Issue 22, pp. 5121 - 5126
Journal Article