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The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 12/2013, Volume 98, Issue 12, pp. 4551 - 4564
Adrenocortical carcinoma (ACC) is an orphan malignancy that has attracted increasing attention during the last decade. Here we provide an update on advances in... 
GROWTH-FACTOR RECEPTOR | POSITRON-EMISSION-TOMOGRAPHY | LAPAROSCOPIC ADRENALECTOMY | CANCER-PATIENTS | STEROIDOGENIC FACTOR-1 | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | PHASE-II | ADJUVANT RADIOTHERAPY | BETA-CATENIN | PROGNOSTIC VALUE | Adrenal Glands - pathology | Lymph Node Excision | Recurrence | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Prognosis | Adrenocortical Carcinoma - surgery | Humans | Adrenocortical Carcinoma - diagnosis | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Neoplasm Proteins - antagonists & inhibitors | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Mitotane - pharmacology | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Adrenal Cortex Neoplasms - diagnosis | Adrenocortical Carcinoma - drug therapy | Antineoplastic Agents, Hormonal - therapeutic use | Adrenocortical Carcinoma - metabolism | Chemotherapy, Adjuvant | Adrenal Glands - drug effects | Mitotane - administration & dosage | Adrenal Cortex Neoplasms - metabolism | Antineoplastic Agents, Hormonal - pharmacology | Antineoplastic Agents, Hormonal - administration & dosage | Adrenal Cortex Neoplasms - surgery | Adrenal Glands - surgery | Mitotane - therapeutic use | Adrenal Cortex Neoplasms - drug therapy | Animals | Adrenal Glands - metabolism | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Decision Trees | Neoplasm Staging
Journal Article
Endocrinology, ISSN 0013-7227, 11/2015, Volume 156, Issue 11, pp. 3895 - 3908
Adrenocortical carcinoma (ACC) is a rare malignancy that harbors a dismal prognosis in advanced stages. Mitotane is approved as an orphan drug for treatment of... 
ADJUVANT MITOTANE | ACTIVATION | UNFOLDED PROTEIN RESPONSE | CHOLESTERYL ESTER | METABOLISM | QUANTIFICATION | MITOCHONDRIA | ENDOCRINOLOGY & METABOLISM | ACAT | CANCER | EXPRESSION | Immunohistochemistry | Transcription Factor CHOP - genetics | Gas Chromatography-Mass Spectrometry | Oligonucleotide Array Sequence Analysis | Apoptosis - drug effects | Humans | Immunoblotting | Endoplasmic Reticulum Stress - genetics | Mitotane - pharmacology | Adrenocortical Carcinoma - drug therapy | Antineoplastic Agents, Hormonal - therapeutic use | Adrenocortical Carcinoma - metabolism | HEK293 Cells | Sterol O-Acyltransferase - metabolism | Gene Expression Regulation, Neoplastic - drug effects | Adrenal Cortex Neoplasms - metabolism | Cell Survival - drug effects | Antineoplastic Agents, Hormonal - pharmacology | Endoplasmic Reticulum Stress - drug effects | Adrenocortical Carcinoma - genetics | Transcriptome - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Mitotane - therapeutic use | Hep G2 Cells | Adrenal Cortex Neoplasms - drug therapy | Adrenal Cortex Neoplasms - genetics | Disease-Free Survival | Cell Line, Tumor | Sterol O-Acyltransferase - genetics | HeLa Cells | Lipids - analysis | Transcription Factor CHOP - metabolism | Sterol O-Acyltransferase - antagonists & inhibitors | Index Medicus | Abridged Index Medicus
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Journal Article
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Endocrinology and Metabolism Clinics of North America, ISSN 0889-8529, 06/2015, Volume 44, Issue 2, pp. 411 - 434
Journal Article
Cancer Research, ISSN 0008-5472, 06/2010, Volume 70, Issue 11, pp. 4666 - 4675
MicroRNAs (miRNAs) act at the posttranscriptional level to control gene expression in virtually every biological process, including oncogenesis. Here, we... 
OVEREXPRESSION | FACTOR-II | ONCOLOGY | UPSTREAM | RECEPTOR | CELL-PROLIFERATION | EXPRESSION PROFILES | CARCINOMA | CONTRIBUTES | HUMAN OVARIAN-CANCER | MTOR | Humans | Cell Growth Processes - physiology | MicroRNAs - metabolism | Transplantation, Heterologous | Intracellular Signaling Peptides and Proteins - metabolism | Adrenocortical Carcinoma - pathology | Adrenocortical Carcinoma - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Adrenocortical Adenoma - genetics | Female | Everolimus | Adrenal Cortex Neoplasms - metabolism | Protein-Serine-Threonine Kinases - metabolism | Somatomedins - metabolism | Sirolimus - analogs & derivatives | Adrenocortical Carcinoma - genetics | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Adrenal Cortex Neoplasms - pathology | Mice, SCID | Adrenocortical Adenoma - pathology | Sirolimus - pharmacology | Adrenocortical Adenoma - metabolism | Adrenal Cortex Neoplasms - genetics | Animals | Mice, Inbred NOD | Mice | MicroRNAs - genetics | TOR Serine-Threonine Kinases | Somatomedins | Sirolimus | Protein-Serine-Threonine Kinases | Biochemistry, Molecular Biology | Adrenocortical Adenoma | Adrenocortical Carcinoma | Intracellular Signaling Peptides and Proteins | Cell Growth Processes | Life Sciences | Adrenal Cortex Neoplasms | MicroRNAs
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Endocrine-Related Cancer, ISSN 1351-0088, 12/2011, Volume 18, Issue 6, pp. 643 - 655
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EMBO reports, ISSN 1469-221X, 09/2016, Volume 17, Issue 9, pp. 1264 - 1280
Several stimuli induce programmed cell death by increasing Ca 2+ transfer from the endoplasmic reticulum ( ER ) to mitochondria. Perturbation of this process... 
MAM | apoptosis | endocrine cancer | adrenal cortex | mitochondria | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDENTIFICATION | MAMMALIAN-CELLS | CANCER | CELL BIOLOGY | ENDOPLASMIC-RETICULUM CA2 | MEMBRANE ORGANIZATION | MITOFILIN | PROTEOME-SCALE MAP | DREIFUSS MUSCULAR-DYSTROPHY | ADRENOCORTICAL CARCINOMA | EXPRESSION | Prognosis | Transcription Factors - chemistry | Apoptosis - drug effects | Calcium - metabolism | Humans | Endoplasmic Reticulum - metabolism | Mitochondria - ultrastructure | Endoplasmic Reticulum - ultrastructure | Mitotane - pharmacology | DNA-Binding Proteins - metabolism | Adrenocortical Carcinoma - metabolism | Membrane Potential, Mitochondrial | Steroids - pharmacology | Adrenocortical Carcinoma - mortality | Protein Interaction Domains and Motifs | Gene Expression | Antineoplastic Agents, Hormonal - pharmacology | Adrenocortical Carcinoma - genetics | Mitochondria - metabolism | Transcription Factors - genetics | DNA-Binding Proteins - genetics | DNA-Binding Proteins - chemistry | Mitochondrial Membranes - metabolism | Protein Transport | Transcription Factors - metabolism | Protein Binding | Antigens | Mitochondria | Chemotherapy | Calcium | Endoplasmic reticulum | Cancer | Apoptosis | Life Sciences | Cellular Biology | Biochemistry, Molecular Biology | Scientific Reports | Autophagy & Cell Death | Scientific Report
Journal Article
Endocrine-Related Cancer, ISSN 1351-0088, 08/2015, Volume 22, Issue 4, pp. 531 - 543
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