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1. Full Text The central role of mosquito cytochrome P450 CYP6Zs in insecticide detoxification revealed by functional expression and structural modelling
by Chandor-Proust, A and Bibby, J and Regent-Kloeckner, M and Roux, J and Guittard-Crilat, E and Poupardin, R and Riaz, MA and Paine, M and Dauphin-Villemant, C and Reynaud, S and David, JP
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 10/2013, Volume 455, Issue 1, pp. 75 - 85
The resistance of mosquitoes to chemical insecticides is threatening vector control programmes worldwide. Cytochrome P450 monooxygenases (CYPs) are known to... 
B | DENGUE VECTOR | recombinant system | VECTOR AEDES-AEGYPTI | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | insecticide | IN-VITRO METABOLISM | ANOPHELES-GAMBIAE | resistance | mosquito | YEAST | MALARIA VECTOR | cytochrome P450 monooxygenase | metabolism | P450 | pyrethroid | Inactivation, Metabolic | Insecticides - chemistry | NADPH-Ferrihemoprotein Reductase - genetics | Saccharomyces cerevisiae - genetics | Benzoates - metabolism | Cytochrome P-450 Enzyme System - metabolism | Insecticide Resistance - genetics | NADPH-Ferrihemoprotein Reductase - chemistry | Saccharomyces cerevisiae - drug effects | Isoenzymes - chemistry | Pyrethrins - pharmacology | Insect Vectors - drug effects | Isoenzymes - metabolism | Insecticide Resistance - drug effects | Aedes - enzymology | Pyrethrins - metabolism | Insect Proteins - metabolism | Insect Vectors - enzymology | Insecticides - pharmacology | Benzaldehydes - chemistry | Escherichia coli - enzymology | NADPH-Ferrihemoprotein Reductase - metabolism | Oxidation-Reduction | Isoenzymes - genetics | Anopheles - drug effects | Insect Proteins - genetics | Benzaldehydes - pharmacology | Aedes - drug effects | Pyrethrins - chemistry | Anopheles - enzymology | Benzaldehydes - metabolism | Cytochrome P-450 Enzyme System - chemistry | Animals | Genetic Engineering | Insecticides - metabolism | Escherichia coli - genetics | Insect Proteins - chemistry | Cytochrome P-450 Enzyme System - genetics | Saccharomyces cerevisiae - enzymology | Molecular Docking Simulation | AeCPR, Aedes aegypti CPR | 7-OH, 7-hydroxycoumarin | SRS, substrate recognition site | CPR, NADPH-cytochrome P450-reductase | Rt, retention time | Cyt b5, cytochrome b5 | PBAld, 3-phenoxybenzaldehyde | qPCR, quantitative real-time PCR | PBA, 3-phenoxybenzoic acid | PBAlc, 3-phenoxybenzoic alcohol | TFA, trifluoroacetic acid
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2. Full Text Insect fat body: Energy, metabolism, and regulation
by Arrese, Estela L and Soulages, Jose L
Annual Review of Entomology, ISSN 0066-4170, 01/2010, Volume 55, Issue 1, pp. 207 - 225
The fat body plays major roles in the life of insects. It is a dynamic tissue involved in multiple metabolic functions. One of these functions is to store and... 
Adipokinetic hormone | Lipase | Glycogen | Octopamine | Lipid | Lipolysis | octopamine | LOCUSTA-MIGRATORIA | DROSOPHILA-MELANOGASTER | GLYCOGEN-PHOSPHORYLASE | adipokinetic hormone | lipase | COCKROACH PERIPLANETA-AMERICANA | MOSQUITO AEDES-AEGYPTI | glycogen | lipid | STORAGE DROPLET PROTEIN-1 | ENTOMOLOGY | lipolysis | CULEX-PIPIENS DIPTERA | LARVAL MANDUCA-SEXTA | HORMONE-INDUCED LIPOLYSIS | Animals | Energy Metabolism | Insect Hormones - metabolism | Carbohydrate Metabolism | Lipid Metabolism | Oligopeptides - metabolism | Pyrrolidonecarboxylic Acid - analogs & derivatives | Fat Body - metabolism | Pyrrolidonecarboxylic Acid - metabolism | Insecta - metabolism | Physiological aspects | Fat cells | Research | Insects | Entomology
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3. Full Text Biology of Zika virus infection in human skin cells
by Hamel, Rodolphe and Dejarnac, Ophélie and Wichit, Sineewanlaya and Ekchariyawat, Peeraya and Neyret, Aymeric and Luplertlop, Natthanej and Perera-Lecoin, Manuel and Surasombatpattana, Pornapat and Talignani, Loïc and Thomas, Frédéric and Cao-Lormeau, Van-Mai and Choumet, Valérie and Briant, Laurence and Desprès, Philippe and Amara, Ali and Yssel, Hans and Missé, Dorothée
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 17, pp. 8880 - 8896
Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family, which includes dengue, West Nile, yellow fever, and Japanese encephalitis viruses, that... 
HUMAN DENDRITIC CELLS | DENGUE-VIRUS | REPLICATION | VIROLOGY | AEDES-ALBOPICTUS | ENCEPHALITIS-VIRUS | IMMUNE-RESPONSES | WEST-NILE-VIRUS | HEPARAN-SULFATE | AUTOPHAGY | I INTERFERON | Keratinocytes - virology | Membrane Glycoproteins - metabolism | Dendritic Cells - immunology | Humans | Flaviviridae - physiology | Virus Internalization | Interferon-Induced Helicase, IFIH1 | Lectins, C-Type - metabolism | Phagosomes - immunology | RNA Interference | Vero Cells | Myxovirus Resistance Proteins - biosynthesis | DEAD Box Protein 58 | Toll-Like Receptor 3 - immunology | Receptor Protein-Tyrosine Kinases - metabolism | Toll-Like Receptor 3 - metabolism | Cell Adhesion Molecules - metabolism | RNA, Small Interfering | Receptors, Cell Surface - genetics | Cell Adhesion Molecules - genetics | Ubiquitins - biosynthesis | Interferon-beta - immunology | Receptors, Virus - metabolism | Cercopithecus aethiops | Receptors, Virus - genetics | Lectins, C-Type - genetics | Insect Vectors - virology | Autophagy - immunology | Aedes - virology | Flaviviridae - immunology | Toll-Like Receptor 7 - immunology | HEK293 Cells | Toll-Like Receptor 3 - genetics | DEAD-box RNA Helicases - metabolism | Dendritic Cells - virology | Skin - virology | Flaviviridae Infections - immunology | Skin - immunology | Fibroblasts - virology | Proto-Oncogene Proteins - metabolism | Cells, Cultured | Interferon-beta - biosynthesis | Receptors, Cell Surface - metabolism | Proto-Oncogene Proteins - genetics | Hepatitis A Virus Cellular Receptor 1 | Flaviviridae Infections - virology | Membrane Glycoproteins - genetics | DEAD-box RNA Helicases - genetics | Animals | Receptor Protein-Tyrosine Kinases - genetics | Virus Replication | Cytokines - biosynthesis | Life Sciences | Microbiology and Parasitology | Virology
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4. Full Text Temporal Coordination of Carbohydrate Metabolism during Mosquito Reproduction
by Hou, Yuan and Wang, Xue-Li and Saha, Tusar T and Roy, Sourav and Zhao, Bo and Raikhel, Alexander S and Zou, Zhen
PLoS Genetics, ISSN 1553-7390, 07/2015, Volume 11, Issue 7, p. e1005309
Hematophagous mosquitoes serve as vectors of multiple devastating human diseases, and many unique physiological features contribute to the incredible... 
FAT-BODY | BHLH-PAS PROTEINS | KINASE | GENETICS & HEREDITY | GENE-EXPRESSION | METHOPRENE-TOLERANT | RECEPTOR | KRUPPEL HOMOLOG 1 | AEDES-AEGYPTI | JUVENILE-HORMONE | DROSOPHILA | Receptors, Steroid - metabolism | Carbohydrate Metabolism - genetics | Insect Proteins - genetics | Reproduction - genetics | Reproduction - physiology | Juvenile Hormones - genetics | Aedes - metabolism | Triglycerides - metabolism | Carbohydrate Metabolism - physiology | Trehalose - metabolism | Animals | Glycogen - metabolism | RNA Interference | Receptors, Steroid - genetics | Adenosine Triphosphate - metabolism | Glucose - metabolism | RNA, Small Interfering | Fat Body - metabolism | Insect Proteins - metabolism | Enzymes | Mosquitoes | Metabolites | Physiology | Metabolism | Gene expression | Experiments
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5. Full Text Discovery of a novel insect neuropeptide signaling system closely related to the insect adipokinetic hormone and corazonin hormonal systems
by Hansen, Karina K and Stafflinger, Elisabeth and Schneider, Martina and Hauser, Frank and Cazzamali, Giuseppe and Williamson, Michael and Kollmann, Martin and Schachtner, Joachim and Grimmelikhuijzen, Cornelis J. P
Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 14, pp. 10736 - 10747
Neuropeptides and their G protein-coupled receptors (GPCRs) play a central role in the physiology of insects. One large family of insect neuropeptides are the... 
APIS-MELLIFERA | MOLECULAR-IDENTIFICATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MALARIA MOSQUITO | PROTEIN-COUPLED RECEPTORS | CARDIOACTIVE PEPTIDE | BEETLE TRIBOLIUM-CASTANEUM | NEUROHORMONE GPCRS | MOSQUITO ANOPHELES-GAMBIAE | DROSOPHILA | GENOME | Anopheles - metabolism | Cricetulus | Receptors, G-Protein-Coupled - metabolism | Anopheles - genetics | Receptors, G-Protein-Coupled - classification | Receptors, Neuropeptide - metabolism | Phylogeny | Pyrrolidonecarboxylic Acid - analogs & derivatives | RNA, Messenger - metabolism | Pyrrolidonecarboxylic Acid - metabolism | Aedes - metabolism | Immunoenzyme Techniques | Insect Hormones - metabolism | Insect Hormones - genetics | Neuropeptides - genetics | Insect Proteins - metabolism | Tribolium - metabolism | CHO Cells | Drosophila - genetics | Genes, Insect | Cricetinae | Signal Transduction | RNA, Messenger - genetics | Insect Proteins - genetics | Receptors, Neuropeptide - genetics | Neuropeptides - metabolism | Oligopeptides - metabolism | Insecta - genetics | Reverse Transcriptase Polymerase Chain Reaction | Aedes - genetics | Insecta - metabolism | Animals | Insect Proteins - chemistry | Insect Hormones - chemistry | Tribolium - genetics | Receptors, G-Protein-Coupled - genetics | Drosophila - metabolism | Evolution, Molecular | Neuropeptides - chemistry | Neurochemistry | Peptides | G Proteins | Neurobiology | Organisms | Hormones | Neuropeptide | Neuroscience | Neurotransmitters | Receptors | Evolution | Coupled Receptors (GPCR) | Peptide | Insect
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6. Full Text Mitochondrial physiology in the major arbovirus vector Aedes aegypti: Substrate preferences and sexual differences define respiratory capacity and superoxide production
by Correa Soares, Juliana B. R and Gaviraghi, Alessandro and Oliveira, Marcus F
PLoS ONE, ISSN 1932-6203, 03/2015, Volume 10, Issue 3, p. e0120600
Adult females of Aedes aegypti are facultative blood sucking insects and vectors of Dengue and yellow fever viruses. Insect dispersal plays a central role in... 
COMPLEX I | REACTIVE OXYGEN | DROSOPHILA-MELANOGASTER | AMINO-ACIDS | MULTIDISCIPLINARY SCIENCES | OXYGEN SPECIES GENERATION | FLIGHT-MUSCLE MITOCHONDRIA | BROWN ADIPOSE-TISSUE | HYDROGEN-PEROXIDE RELEASE | OXIDATIVE-METABOLISM | INSECT FLIGHT | Arboviruses - isolation & purification | Proline - metabolism | Humans | Mitochondria, Muscle - metabolism | Glycerophosphates - metabolism | Male | Electron Transport Complex I - metabolism | Insect Vectors - virology | Aedes - virology | Aedes - anatomy & histology | Superoxides - metabolism | Pyruvic Acid - metabolism | Female | Insect Proteins - metabolism | NAD - metabolism | Aedes - physiology | Oxidation-Reduction | Body Size | Cytochromes c - metabolism | Oxygen Consumption | Sex Characteristics | Glycerolphosphate Dehydrogenase - metabolism | Animals | Insect Vectors - physiology | Dengue - transmission | Phosphates | Glycerin | Enzymes | Physiological aspects | Proline | Glycerol | Development and progression | Mitochondrial DNA | Superoxide | Yellow fever | Cytochrome | Energy metabolism | Phosphorylation | Hydrogen peroxide | Blood sucking | Flight | Viral diseases | Amino acids | Viruses | Males | Aquatic insects | Tropical diseases | Electron transport chain | Mitochondria | Energy | Energy transmission | Dispersal | Substrate preferences | Physiology | Oxidation | Sugar | Vector-borne diseases | Cellular manufacture | Carbohydrates | Flight muscle | Dengue | Muscles | Vectors | Metabolism | Gene expression | Organelles | Fatty acids | Substrates | Fever | Musculoskeletal system | Mosquitoes | Disease transmission | Oxidative phosphorylation | Insects | Energy demand | Respiration | Females
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7. Full Text Sensitivity of Aedes aegypti adults (Diptera: Culicidae) to the vapors of Eucalyptus essential oils
by Lucia, Alejandro and Licastro, Susana and Zerba, Eduardo and Audino, Paola Gonzalez and Masuh, Hector
Bioresource Technology, ISSN 0960-8524, 2009, Volume 100, Issue 23, pp. 6083 - 6087
Vapors of essential oils extracted from various species of ( , , , , , , , , ssp. globulus, ssp. maidenii, and the hybrids × and × ) and their major components... 
Knockdown | Fumigant activity | Vapor pressure | Mosquito | 1,8-Cineole | AGRICULTURAL ENGINEERING | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | ENERGY & FUELS | LARVAE | Insect Repellents - pharmacology | Insecticides | Aedes - drug effects | Pressure | Aedes - metabolism | Gases | Plant Extracts - metabolism | Animals | Cyclohexanols - metabolism | Time Factors | Monoterpenes - metabolism | Insecticide Resistance - drug effects | Oils, Volatile - metabolism | Plant Oils | Eucalyptus - metabolism | Dichlorvos - metabolism | Crosses, Genetic | Mosquitoes | Adults | Yellow fever | Organic compounds | Index Medicus
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8. Full Text Wolbachia induces reactive oxygen species (ROS)-dependent activation of the Toll pathway to control dengue virus in the mosquito Aedes aegypti
by Pan, Xiaoling and Zhou, Guoli and Wu, Jiahong and Bian, Guowu and Lu, Peng and Raikhel, Alexander S and Xi, Zhiyong
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 01/2012, Volume 109, Issue 1, pp. E23 - E31
Wolbachia are maternally transmitted symbiotic bacteria that can spread within insect populations because of their unique ability to manipulate host... 
Innate immunity | Antiviral resistance | Population replacement | antiviral resistance | population replacement | MULTIDISCIPLINARY SCIENCES | FACTOR-KAPPA-B | ANOPHELES-GAMBIAE | DROSOPHILA | LIFE-SHORTENING WOLBACHIA | VECTOR | TRANSMISSION | innate immunity | PLASMODIUM | INFECTION | ANTIVIRAL IMMUNITY | EXPRESSION | Defensins - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Antioxidants - metabolism | Humans | Gram-Negative Bacterial Infections - immunology | Wolbachia - physiology | Gene Knockdown Techniques | Gram-Negative Bacterial Infections - microbiology | Aedes - virology | Toll-Like Receptors - metabolism | Dengue - immunology | Fat Body - metabolism | Insect Proteins - metabolism | Cecropins - metabolism | Animals, Genetically Modified | Gene Expression Regulation | Insect Proteins - genetics | Signal Transduction - genetics | Dengue - virology | Organ Specificity | Aedes - genetics | Aedes - microbiology | Models, Immunological | Animals | Toll-Like Receptors - genetics | Dengue Virus - physiology | Biological Sciences | PNAS Plus
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9. Full Text Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides
by Nässel, Dick R and Broeck, Jozef Vanden and Stockholms universitet and Naturvetenskapliga fakulteten and Zoologiska institutionen
Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2016, Volume 73, Issue 2, pp. 271 - 290
Insulin, insulin-like growth factors (IGFs) and insulin-like peptides (ILPs) are important regulators of metabolism, growth, reproduction and lifespan, and... 
Life Sciences | Biochemistry, general | Neuropeptide release | Life Sciences, general | Insulin-like growth factors | Nutrient sensing | Metabolism | Insulin | Biomedicine general | Cell Biology | IGF BINDING | YELLOW-FEVER MOSQUITO | BIOCHEMISTRY & MOLECULAR BIOLOGY | MOSQUITO AEDES-AEGYPTI | EXTENDS LIFE-SPAN | JUVENILE-HORMONE BIOSYNTHESIS | CELL BIOLOGY | SILKMOTH BOMBYX-MORI | SCHISTOCERCA-GREGARIA | AMINO-ACID-SEQUENCE | CAENORHABDITIS-ELEGANS | GROWTH-FACTORS | Signal Transduction | Intercellular Signaling Peptides and Proteins - genetics | Insect Proteins - genetics | Neuropeptides - metabolism | Hormones | Drosophila Proteins - metabolism | Insecta - genetics | Drosophila - physiology | Insecta - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Insulin - metabolism | Reproduction | Animals | Somatomedins - genetics | Insecta - physiology | Neurons - metabolism | Drosophila - metabolism | Drosophila Proteins - genetics | Neuropeptides - genetics | Insulin - genetics | Insect Proteins - metabolism | Somatomedins - metabolism | Drosophila - genetics | Ecdysteroids | Drosophila | Zoology | Neuropeptides | Glucose | Dextrose | Neurophysiology | Fruit-flies | Insects | Physiological aspects | Cellular signal transduction | Binding proteins | Protein binding | Signal transduction | Nutrition | Biological Sciences | Naturvetenskap | Biologiska vetenskaper | Natural Sciences
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10. Full Text A large population of diverse neurons in the Drosophila central nervous system expresses short neuropeptide F, suggesting multiple distributed peptide functions
by Nässel, Dick R and Enell, Lina E and Santos, Jonathan G and Wegener, Christian and Johard, Helena A.D and Stockholms universitet and Naturvetenskapliga fakulteten and Zoologiska institutionen
BMC Neuroscience, ISSN 1471-2202, 09/2008, Volume 9, Issue 1, pp. 90 - 90
Background: Insect neuropeptides are distributed in stereotypic sets of neurons that commonly constitute a small fraction of the total number of neurons.... 
MUSHROOM BODIES | IMMUNOREACTIVE NEURONS | IMMUNOCYTOCHEMICAL LOCALIZATION | TYROSINE-HYDROXYLASE | FRUIT-FLY | RECEPTOR | POSTEMBRYONIC DEVELOPMENT | AEDES-AEGYPTI | TRANSCRIPTION FACTOR | MELANOGASTER | NEUROSCIENCES | Immunohistochemistry | Central Nervous System - metabolism | gamma-Aminobutyric Acid - metabolism | Acetylcholine - metabolism | Drosophila Proteins - metabolism | Neurotransmitter Agents - genetics | In Situ Hybridization | Basic Helix-Loop-Helix Transcription Factors - metabolism | Time Factors | Mass Spectrometry | Cell Adhesion Molecules, Neuronal - metabolism | Larva - genetics | Neurons - metabolism | Neuropeptides - genetics | Mushroom Bodies - metabolism | Gene Expression | Basic Helix-Loop-Helix Transcription Factors - genetics | Larva - metabolism | Neurotransmitter Agents - metabolism | Axons - metabolism | Neuropeptides - metabolism | Cell Adhesion Molecules, Neuronal - genetics | Olfactory Receptor Neurons - metabolism | Animals | Interneurons - metabolism | Glutamic Acid - metabolism | Drosophila Proteins - genetics | Drosophila melanogaster | Physiological aspects | Neuropeptides | Chemical properties | Properties | Drosophila | Central nervous system | Biological Sciences | Biology | Biologi | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
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