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1. Full Text The study of inhibitory effects and mechanism of carboxylate chitooligomer on melanin, prepared by laccase/TEMPO system
by Zhen, Xiaoqin and Hao, Dongzhao and Pei, Jicheng and Zhang, Fangdong and Zhang, Xinli and Liu, Haitang and Wang, Jing and Bian, Nengyuan and Li, Ying and Bu, Xin
Carbohydrate Polymers, ISSN 0144-8617, 03/2019, Volume 207, pp. 391 - 397
Schematic illustration of reaction mechanism of C-COS and tyrosinase. A carboxylate chitooligomer (C-COS) containing carboxyl groups attached to chitooligomer... 
Inhibition | Chitooligomer (COS) | Pigmentation | Laccase/TEMPO | Tyrosinase (TYR) | Mechanism | OXIDATION | POLYMER SCIENCE | ACID | LOADED MICELLES | CHITOSAN | CHEMISTRY, ORGANIC | TYROSINASE INHIBITORS | ADSORPTION | IMPROVEMENT | CHEMISTRY, APPLIED | EXTRACTS | SPECTRA | WHITENING AGENTS | Chitin - chemical synthesis | Melanins - antagonists & inhibitors | Melanins - chemistry | Oxidation-Reduction | Chelating Agents - chemistry | Skin Lightening Preparations - chemistry | Chitin - chemistry | Laccase - chemistry | Monophenol Monooxygenase - antagonists & inhibitors | Enzyme Inhibitors - chemical synthesis | Levodopa - chemistry | Cyclic N-Oxides - chemistry | Copper - chemistry | Chitin - analogs & derivatives | Green Chemistry Technology - methods | Skin Lightening Preparations - chemical synthesis | Models, Biological | Enzyme Inhibitors - chemistry | Chelating Agents - chemical synthesis | Agaricales - enzymology | Monophenol Monooxygenase - chemistry | Tyrosine - chemistry
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2. Full Text A tyrosinase biosensor based on ordered mesoporous carbon-Au/l-lysine/Au nanoparticles for simultaneous determination of hydroquinone and catechol
by Tang, Lin and Zhou, Yaoyu and Zeng, Guangming and Li, Zhen and Liu, Yuanyuan and Zhang, Yi and Chen, Guiqiu and Yang, Guide and Lei, Xiaoxia and Wu, Mengshi
Analyst, ISSN 0003-2654, 06/2013, Volume 138, Issue 12, pp. 3552 - 3560
A novel biosensor was developed based on tyrosinase immobilization with ordered mesoporous carbon-Au (OMC-Au), L-lysine membrane and Au nanoparticles on a... 
GOLD NANOPARTICLES | CHEMISTRY, ANALYTICAL | ELECTRON-TRANSFER | SENSITIVE SIMULTANEOUS DETERMINATION | PHENOL | OXIDASE | SENSOR | HYDROGEN-PEROXIDE | DIHYDROXYBENZENE ISOMERS | COMPOSITE | IMMOBILIZATION | Gold - chemistry | Enzymes, Immobilized - chemistry | Enzymes, Immobilized - metabolism | Biocatalysis | Oxidation-Reduction | Hydroquinones - chemistry | Metal Nanoparticles - chemistry | Hydroquinones - analysis | Membranes, Artificial | Catechols - chemistry | Isomerism | Carbon - chemistry | Monophenol Monooxygenase - metabolism | Electrodes | Time Factors | Water - chemistry | Electrochemistry | Biosensing Techniques - methods | Kinetics | Porosity | Lysine - chemistry | Agaricales - enzymology | Catechols - analysis | Monophenol Monooxygenase - chemistry | Hydroquinone | Scanning electron microscopy | Gold | Catechol | Biosensors | Isomers | Tyrosinase
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3. Full Text Characteristic anti-inflammatory and antioxidative effects of enzymatic- and acidic- hydrolysed mycelium polysaccharides by Oudemansiella radicata on LPS-induced lung injury
by Gao, Zheng and Liu, Xinchao and Wang, Wenshuai and Yang, Qihang and Dong, Yuhan and Xu, Nuo and Zhang, Jianjun and Zhang, Chen and Song, Xinling and Ren, Zhenzhen and Zhao, Fulan and Jia, Le
Carbohydrate Polymers, ISSN 0144-8617, 01/2019, Volume 204, pp. 142 - 151
The present work investigated the antioxidative, anti-inflammatory and pulmonary protective effects of enzymatic- and acid- hydrolysed mycelia polysaccharides... 
Oudemansiella radicata | Acute lung injury | Antioxidant | Pulmonary protective | Anti-inflammatory | Enzymatic- acid- hydrolysed mycelia polysaccharide | FRUITING BODY | SIGNALING PATHWAYS | POLYMER SCIENCE | CHEMISTRY, ORGANIC | ANTITUMOR-ACTIVITY | ANTIAGING ACTIVITIES | ZINC POLYSACCHARIDES | IN-VITRO | LIPOPOLYSACCHARIDE | MICE | PLEUROTUS-DJAMOR | CHEMISTRY, APPLIED | NF-KAPPA-B | Cellulase - chemistry | Tumor Necrosis Factor-alpha - metabolism | Lung Injury - pathology | Antioxidants - chemistry | Polygalacturonase - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Interleukin-1alpha - metabolism | Male | Protective Agents - chemistry | Protective Agents - therapeutic use | Polysaccharides - toxicity | Polysaccharides - chemistry | Lung Injury - drug therapy | Interleukin-6 - metabolism | Polysaccharides - therapeutic use | Lung - pathology | Glucuronidase - chemistry | Anti-Inflammatory Agents, Non-Steroidal - toxicity | Multienzyme Complexes - chemistry | Antioxidants - toxicity | Hydrolysis | Antioxidants - therapeutic use | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Mice | Mycelium - chemistry | Protective Agents - toxicity | Agaricales - chemistry | Antioxidants | Acute respiratory distress syndrome | Prevention | Enzymes | Polysaccharides | C-reactive protein | Interleukins | Anti-inflammatory drugs | Analysis | Superoxide | Mitogens | Index Medicus
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4. Full Text Toward the Antioxidant and Chemical Characterization of Mycorrhizal Mushrooms from Northeast Portugal
by Reis, Filipa S and Heleno, Sandrina A and Barros, Lillian and Sousa, Maria João and Martins, Anabela and Santos‐Buelga, Celestino and Ferreira, Isabel C.F.R
Journal of Food Science, ISSN 0022-1147, 08/2011, Volume 76, Issue 6, pp. C824 - C830
:  Mushrooms are widely appreciated all over the world for their nutritional properties and pharmacological value as sources of important bioactive compounds.... 
bioactive compounds | mycorrhizal mushrooms | antioxidant activity | nutrients | Mycorrhizal mushrooms | Nutrients | Bioactive compounds | Antioxidant activity | NUTRITIONAL-VALUE | TURKEY | FOOD SCIENCE & TECHNOLOGY | WILD EDIBLE MUSHROOMS | PHENOLICS | RADICAL SCAVENGING CAPACITY | AMINO-ACID CONTENTS | ASSAYS | REDUCING POWER | Antioxidants - chemistry | Species Specificity | Tricholoma - metabolism | Antioxidants - metabolism | Amanita - metabolism | Basidiomycota - metabolism | Portugal | Ascorbic Acid - metabolism | Lipids - chemistry | Cortinarius - metabolism | Mycorrhizae - chemistry | Mannitol - metabolism | Arabinose - metabolism | Tocopherols - chemistry | Fatty Acids - metabolism | Fatty Acids - chemistry | Agaricales - metabolism | Amanita - chemistry | Cortinarius - chemistry | Basidiomycota - chemistry | Phenols - metabolism | Plant Roots - microbiology | Tricholoma - chemistry | Tocopherols - metabolism | Trehalose - metabolism | Carbohydrates - chemistry | Mycorrhizae - metabolism | Trees - microbiology | Phenols - chemistry | Carbohydrates - analysis | Lipids - analysis | Agaricales - chemistry | Antioxidants | Symbiosis | Composition | Mushrooms, Edible | Metabolites | Nutritional aspects | Chemical properties | Research
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5. Full Text Purification, chemical characterization and antioxidant activities of polysaccharides isolated from Mycena dendrobii
by Liang, Xiao-xia and Gao, Ying-ying and Pan, Yan and Zou, Yuan-feng and He, Min and He, Chang-liang and Li, Li-xia and Yin, Zhong-qiong and Lv, Cheng
Carbohydrate Polymers, ISSN 0144-8617, 01/2019, Volume 203, pp. 45 - 51
Two polysaccharides, MDP-1 and MDP-2, were obtained from the fermentation liquid of by anion exchange chromatography and gel filtration. Their chemical... 
Polysaccharides | M. dendrobii | Antioxidant activity | Physicochemical properties | EXTRACTION | POLYMER SCIENCE | CHEMISTRY, ORGANIC | OPTIMIZATION | CHEMISTRY, APPLIED | LIGUSTICUM-CHUANXIONG | SULFATED POLYSACCHARIDES | Free Radical Scavengers - chemistry | Hydroxyl Radical - chemistry | Polysaccharides - isolation & purification | Picrates - chemistry | Superoxides - chemistry | Polysaccharides - chemistry | Biphenyl Compounds - chemistry | Free Radical Scavengers - isolation & purification | Hexoses - chemistry | Agaricales - chemistry | Antioxidants | Yuan (China) | Hydroxides | Superoxide | Fermentation | Sugars | Monosaccharides
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6. Full Text One-pot green synthesis of Prussian blue nanocubes decorated reduced graphene oxide using mushroom extract for efficient 4-nitrophenol reduction
by Chen, Ruixue and Zhang, Zhiquan and Zhang, Qiuping and Gu, Yue and Tang, Liu and Li, Cong
Analytica Chimica Acta, ISSN 0003-2670, 01/2015, Volume 853, Issue 1, pp. 579 - 587
One-pot green approach to the synthesis of Prussian blue nanocubes/reduced graphene oxide (PBNCs/RGO) nanocomposite had been attempted. It was based on the... 
4-Nitrophenol | Prussian blue nanocubes/reduced graphene oxide | Electrochemical sensor | Mushroom | OXIDATION | CHEMISTRY, ANALYTICAL | SENSITIVE DETERMINATION | DIFFERENTIAL-PULSE VOLTAMMETRY | GRAPHITE OXIDE | P-NITROPHENOL | CARBON-PASTE ELECTRODE | NANOPARTICLES | ELECTROCHEMICAL DETECTION | NANOTUBES | MESOPOROUS SILICA | Water | Microscopy, Electron, Transmission | Electrochemical Techniques | Nanocomposites - chemistry | Oxidation-Reduction | Agaricales - metabolism | Ferrocyanides - chemistry | Oxides - chemistry | Nitrophenols - analysis | Nitrophenols - chemistry | Nanotubes - chemistry | beta-Cyclodextrins - chemistry | Spectrum Analysis, Raman | Graphite - chemistry | Agaricales - chemistry | Usage | Iron compounds | Graphene | Graphite | Electrochemistry | Cyclodextrins | Sensors | Raman spectroscopy | Index Medicus | Scanning electron microscopy | Reduction | Synthesis | Mushrooms | Oxides | Nanostructure | Deposition
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7. Full Text The ectomycorrhizal fungus Paxillus involutus converts organic matter in plant litter using a trimmed brown‐rot mechanism involving Fenton chemistry
by Rineau, Francois and Roth, Doris and Shah, Firoz and Smits, Mark and Johansson, Tomas and Canbäck, Björn and Olsen, Peter Bjarke and Persson, Per and Grell, Morten Nedergaard and Lindquist, Erika and Grigoriev, Igor V and Lange, Lene and Tunlid, Anders and Joint Genome Institute (JGI) and Umeå universitet and Teknisk-naturvetenskapliga fakulteten and Kemiska institutionen
Environmental Microbiology, ISSN 1462-2912, 06/2012, Volume 14, Issue 6, pp. 1477 - 1487
Summary Soils in boreal forests contain large stocks of carbon. Plants are the main source of this carbon through tissue residues and root exudates. A major... 
LACCARIA-BICOLOR | CARBON | BOREAL FOREST | SOIL | DEGRADATION | MICROBIOLOGY | C-14-LABELED LIGNIN | HUMIC SUBSTANCES | MYCORRHIZAL FUNGI | VEGETATIVE MYCELIUM | ECOSYSTEM PROCESSES | Biodegradation, Environmental | Symbiosis | Carbon - metabolism | Trees - metabolism | Nitrogen - metabolism | Plant Roots - metabolism | Agaricales - metabolism | Soil Microbiology | Plants - microbiology | Mycorrhizae - physiology | Wood - metabolism | Mycorrhizae - growth & development | Plant Roots - microbiology | Iron - metabolism | Hydrogen Peroxide - metabolism | Plants - metabolism | Mycorrhizae - chemistry | Ecosystem | Mycorrhizae - metabolism | Agaricales - growth & development | Trees - microbiology | Agaricales - physiology | Naturvetenskap | Natural Sciences | Kemi | Chemical Sciences
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8. Full Text An Enzyme Cascade for Selective Modification of Tyrosine Residues in Structurally Diverse Peptides and Proteins
by Struck, Anna-Winona and Bennett, Matthew R and Shepherd, Sarah A and Law, Brian J. C and Zhuo, Ying and Wong, Lu Shin and Micklefield, Jason
Journal of the American Chemical Society, ISSN 0002-7863, 03/2016, Volume 138, Issue 9, pp. 3038 - 3045
Bioorthogonal chemistry enables a specific moiety in a complex biomolecule to be selectively modified in the presence of many reactive functional groups and... 
CATECHOL-O-METHYLTRANSFERASE | AMINO-ACID | MUSHROOM TYROSINASE | L-METHIONINE ANALOGS | L-DOPA | CROSS-LINKING | CHEMISTRY | CHEMICAL-MODIFICATION | CHEMISTRY, MULTIDISCIPLINARY | BACILLUS-ANEURINOLYTICUS | LIVING CELLS | Fungal Proteins - chemistry | Hydroxylation | Peptides - chemistry | Agaricales - metabolism | Alkylation | Peptides, Cyclic - chemistry | Peptides, Cyclic - metabolism | Monophenol Monooxygenase - metabolism | Levodopa - chemistry | Catechol O-Methyltransferase - metabolism | Tyrosine - metabolism | Peptides - metabolism | Proteins - metabolism | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Catalysis | Catechol O-Methyltransferase - chemistry | Proteins - chemistry | Agaricales - enzymology | Levodopa - metabolism | Monophenol Monooxygenase - chemistry | Tyrosine - chemistry | Fungal Proteins - metabolism | Tyrosine | Proteins | Enzymes | Peptides | Analysis | Research | Chemical properties
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9. Full Text Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion's Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds
by Friedman, Mendel
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 08/2015, Volume 63, Issue 32, pp. 7108 - 7123
The culinary and medicinal mushroom Hericium erinaceus is widely consumed in Asian countries, but apparently not in the United States, for its nutritional and... 
polysaccharides | erinacines | food use | health-promoting properties | immunostimulation | research needs | glycoproteins | sterols | Hericium erinaceus | nutrients | mushrooms | mycelia | resorcinols | multifunctional health properties | antioxidant capacity | cell, rodent, and human studies | volatile compounds | bioactive compounds | phylogenetics | anti-inflammatory effects | fruit bodies | food processing | erinaceolactones | erinacerins | LISTERIA-MONOCYTOGENES | FOOD SCIENCE & TECHNOLOGY | ESCHERICHIA-COLI | cell | CULINARY-MEDICINAL MUSHROOM | AROMATIC-COMPOUNDS | GROWTH-FACTOR (NGF)-SYNTHESIS | and human studies | rodent | AGRICULTURE, MULTIDISCIPLINARY | CHEMISTRY, APPLIED | CAMPYLOBACTER-JEJUNI | ANTIOXIDANT ACTIVITIES | food processing bioactive compounds | BRAN PROTECTS MICE | CHEMICAL-COMPOSITION | SHIITAKE MUSHROOM | Plant Extracts - chemistry | Agaricales - metabolism | Nutritive Value | Humans | Functional Food - analysis | Mycelium - metabolism | Plant Extracts - metabolism | Vegetables - chemistry | Animals | Fruiting Bodies, Fungal - metabolism | Fruiting Bodies, Fungal - chemistry | Vegetables - metabolism | Mycelium - chemistry | Agaricales - chemistry
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10. Full Text Tyrosinase‐catalyzed oxidation of rhododendrol produces 2‐methylchromane‐6,7‐dione, the putative ultimate toxic metabolite: implications for melanocyte toxicity
by Ito, Shosuke and Ojika, Makoto and Yamashita, Toshiharu and Wakamatsu, Kazumasa
Pigment Cell & Melanoma Research, ISSN 1755-1471, 09/2014, Volume 27, Issue 5, pp. 744 - 753
Summary RS‐4‐(4‐Hydroxyphenyl)‐2‐butanol (rhododendrol, RD) was used as a skin‐whitening agent until it was reported to induce leukoderma in July 2013. To... 
sulfhydryl group | whitening agent: tyrosinase | rhododendrol | melanocyte toxicity | Whitening agent: tyrosinase | Melanocyte toxicity | Sulfhydryl group | Rhododendrol | ORTHO-QUINONE | CELLS | 4-S-CYSTEAMINYLPHENOL | MECHANISM | N-PROPIONYL-4-S-CYSTEAMINYLPHENOL | MELANOGENESIS | CELL BIOLOGY | DERMATOLOGY | MUSHROOM TYROSINASE | ONCOLOGY | HYDROXYTYROSOL | SUBSTRATE | CHEMISTRY | Quinones - chemistry | Free Radicals | Glutathione - metabolism | Humans | Superoxides - chemistry | Skin Lightening Preparations - chemistry | Catechols - chemistry | Chromatography, High Pressure Liquid | Monophenol Monooxygenase - toxicity | Spectrophotometry, Ultraviolet | Monophenol Monooxygenase - metabolism | Benzopyrans - chemistry | Skin Lightening Preparations - metabolism | Melanocytes - cytology | Melanocytes - drug effects | Skin Lightening Preparations - toxicity | Oxygen - chemistry | Water - chemistry | Cytosol - metabolism | Butanols - adverse effects | Catalysis | Agaricales - enzymology | Butanols - chemistry | Monophenol Monooxygenase - chemistry | Cellular proteins | Cysteine | Catechin | Thiols | Metabolites | Quinone | Oxidation-reduction reaction | Superoxide | Skin | Chemical properties | Protein binding | Toxicity | Oxidation | Index Medicus
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11. Full Text Design, synthesis and anti-melanogenic effect of cinnamamide derivatives
by Ullah, Sultan and Park, Chaeun and Park, Yujin and Ikram, Muhammad and Lee, Sanggwon and Kang, Dongwan and Yang, Jungho and Akter, Jinia and Yoon, Sik and Chun, Pusoon and Moon, Hyung Ryong
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2018, Volume 26, Issue 21, pp. 5672 - 5681
Pigmentation disorders are attributed to excessive melanin which can be produced by tyrosinase. Therefore, tyrosinase is supposed to be a vital target for the... 
Docking | B10F16 melanoma cells | Tyrosinase inhibitor | Cinnamamide | Melanin | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | FLAVONOIDS | MECHANISMS | TYROSINASE INHIBITORS | POTENT INHIBITORS | DISCOVERY | CINNAMIC ACID-DERIVATIVES | IN-VITRO | BIOSYNTHESIS | AGENTS | Free Radical Scavengers - pharmacology | Amides - chemical synthesis | Free Radical Scavengers - chemistry | Monophenol Monooxygenase - antagonists & inhibitors | Structure-Activity Relationship | Enzyme Inhibitors - chemical synthesis | Pyrones - chemistry | Amides - toxicity | Skin Lightening Preparations - chemical synthesis | Enzyme Inhibitors - chemistry | Enzyme Inhibitors - toxicity | Skin Lightening Preparations - toxicity | Cinnamates - chemical synthesis | Free Radical Scavengers - chemical synthesis | Cinnamates - toxicity | Molecular Structure | Cinnamates - chemistry | Agaricales - enzymology | Monophenol Monooxygenase - chemistry | Amides - pharmacology | Melanins - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Skin Lightening Preparations - chemistry | Skin Lightening Preparations - pharmacology | Cinnamates - pharmacology | Animals | Amides - chemistry | Cell Line, Tumor | Mice | Molecular Docking Simulation | Free Radical Scavengers - toxicity | Medical colleges | Dermatology | Pharmacy | Formulae, receipts, prescriptions | Melanoma | Drugstores | Dermatologic agents | Skin | Free radicals (Chemistry)
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12. Full Text Antitumor polysaccharides from mushrooms: a review on the structural characteristics, antitumor mechanisms and immunomodulating activities
by Meng, Xin and Liang, Hebin and Luo, Lixin
Carbohydrate Research, ISSN 0008-6215, 04/2016, Volume 424, pp. 30 - 41
Mushrooms are popular folk medicines that have attracted considerable attention because of their efficient antitumor activities. This review covers existing... 
Folk medicine | Mushroom polysaccharide | Mechanism | Antitumor | AGARICUS-BLAZEI MURILL | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | WATER-SOLUBLE EXTRACT | BETA-D-GLUCAN | GANODERMA-LUCIDUM EXTRACT | BREAST-CANCER CELLS | PROTEIN-BOUND POLYSACCHARIDE | PORIA-COCOS MYCELIA | AURICULARIA-AURICULA-JUDAE | CHEMISTRY, APPLIED | NF-KAPPA-B | REI-SHI MYCELIA | Polysaccharides - therapeutic use | Immunomodulation - drug effects | Adjuvants, Immunologic - chemistry | Humans | Polysaccharides - chemistry | Antineoplastic Agents - therapeutic use | Antineoplastic Agents - chemistry | Carbohydrate Conformation | Adjuvants, Immunologic - therapeutic use | Agaricales - chemistry | Neoplasms - drug therapy | Polysaccharides
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