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Journal of Comparative Neurology, ISSN 0021-9967, 11/2001, Volume 442, Issue 1, pp. 23 - 34
During a developmental study of the expression of alpha -amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA)-type glutamate receptor subunits in rat spinal... 
aggresomes
Journal Article
AUTOPHAGY, ISSN 1554-8627, 01/2008, Volume 4, Issue 1, pp. 85 - 87
Pathological inclusions containing misfolded proteins are a prominent feature common to many age-related neurodegenerative diseases, including Parkinson's... 
CELLS | Parkinson's disease | autophagy | AGGRESOMES | PROTEIN | parkin | AUTOPHAGIC DEGRADATION | misfolded proteins | DJ-1 | MODEL | HDAC6 | CELL BIOLOGY | inclusion body | RECESSIVE JUVENILE PARKINSONISM | lysine-63 | ubiquitination | PROTEASOME | HUNTINGTONS-DISEASE | aggresome
Journal Article
Nature Immunology, ISSN 1529-2908, 06/2007, Volume 8, Issue 6, pp. 584 - 591
Activation of transcription factor NF-kappa B in the innate immune system is tightly regulated to prevent excessive inflammatory responses. How NF-kappa B... 
E3 LIGASE | LIM DOMAIN PROTEIN | LOCALIZATION | NUCLEAR-BODIES | UBIQUITIN-PROTEASOME SYSTEM | AGGRESOMES | ACTIN | CYTOSKELETON | IMMUNOLOGY | BINDING | EXPRESSION
Journal Article
Journal of Cell Science, ISSN 0021-9533, 07/2018, Volume 131, Issue 14, pp. jcs216671 - jcs216671
Aggresome formation is a major strategy to enable cells to cope with proteasomal stress. Misfolded proteins are assembled into micro-aggregates and transported... 
Aggresome | P38 | Autophagy | SQSTM1 | Proteasome inhibition | MULTIPLE-MYELOMA | CELLS | ACTIVATION | P62/SQSTM1 | P62 | CELL BIOLOGY | LYSOSOMES | p38 | UBIQUITINATED PROTEINS | PROMOTES | AGGREGATION | Stresses | Phosphorylation | Cell survival | Aggresomes | MAP kinase | Activation | Stress | Proteins | Aggregates | Protein folding | Regulatory mechanisms (biology) | Proteasomes | Transport | Phagocytosis
Journal Article
Journal Article
BMB Reports, ISSN 1976-6696, 2017, Volume 50, Issue 1, pp. 37 - 42
The tubby protein (Tub), a putative transcription factor, plays important roles in the maintenance and function of neuronal cells. A splicing defect-causing... 
Aggresome | Obesity | Mutation | Misfolding | Tubby
Journal Article
Ophthalmic Genetics, ISSN 1381-6810, 07/2018, Volume 39, Issue 4, pp. 539 - 543
Objective: This study was undertaken with the objective to investigate the potential involvement of VAX2 in retinal degeneration. Methods: A cohort of macular... 
protein aggregates and aggresomes | protein mislocalization | Cone dystrophy | novel genetic variant | VAX2 | AGGRESOMES | HUMANS | EYE | GENE | GENETICS & HEREDITY | OPHTHALMOLOGY | EXPRESSION | AXIS | Index Medicus
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 2/2018, Volume 439, Issue 1, pp. 75 - 85
Journal Article
FASEB Journal, ISSN 0892-6638, 02/2012, Volume 26, Issue 2, pp. 533 - 545
Journal Article
AUTOPHAGY, ISSN 1554-8627, 01/2011, Volume 7, Issue 1, pp. 104 - 106
The accumulation of misfolded and/or ubiquitinated protein aggregates with a perturbation of autophagy has been described in several human pathologies. A... 
autophagy | inflammation | aggresomes | cystic fibrosis | ROS | Beclin 1 | transglutaminase 2 | p62 | CFTR | CELL BIOLOGY
Journal Article
Virology, ISSN 0042-6822, 03/2019, Volume 529, pp. 216 - 225
Aquareoviruses contain an 11-segmented double-stranded RNA genome. Previous studies indicated that NS38, a virus-encoded putative single-stranded RNA binding... 
Replication | NS38 | Virus host cell interaction | Aquareovirus | VIRUS | AGGRESOMES | RNA | IDENTIFICATION | TRANSLATION | ROTAVIRUS | GRASS CARP REOVIRUS | VIROLOGY | SITES | ASSOCIATION | EXPRESSION
Journal Article
Journal of Immunology, ISSN 0022-1767, 2008, Volume 180, Issue 11, pp. 7697 - 7705
Cystic fibrosis (CF), the most common life-threatening inherited disease in Caucasians, is due to mutations in the CF transmembrane conductance regulator... 
BREAST-CANCER CELLS | PROTEIN | INHIBITION | AGGRESOMES | RECEPTOR-GAMMA | EPITHELIAL-CELLS | DISEASE | AIRWAY INFLAMMATION | KAPPA-B | IMMUNOLOGY | CROSS-LINKS
Journal Article
Aging Cell, ISSN 1474-9718, 12/2019, Volume 18, Issue 6, pp. e13047 - n/a
Cellular mechanisms that act in concert to maintain protein homeostasis (proteostasis) are vital for organismal functionality and survival. Nevertheless,... 
neurodegeneration | linker of nucleoskeleton and cytoskeleton | proteostasis | protein aggregation | NUCLEAR | PROTEOTOXICITY | AGGRESOMES | FAMILY | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | CAENORHABDITIS-ELEGANS | AGE-ONSET | STRESS | Index Medicus | Original
Journal Article
Autophagy, ISSN 1554-8627, 04/2019, Volume 15, Issue 4, pp. 613 - 630
ULK1 (unc-51 like autophagy activating kinase 1) is a core component at multiple steps of canonical macroautophagy/autophagy. The activity of ULK1 is tightly... 
breast cancer | MAP1LC3B | Aggresomes | pimozide | noncanonical autophagy | deubiquitinating enzymes | CALPAIN | PHOSPHORYLATION | STABILITY | COMPLEXES | MECHANISMS | CHEMOTHERAPY | CELL BIOLOGY | BREAST-CANCER | INHIBITION | PATHWAY | DEUBIQUITINATION
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2012, Volume 287, Issue 23, pp. 19687 - 19698
Journal Article