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06/2014
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-inducible poly(ADP-ribose) polymerase (TiPARP/ARTD14) is a member of the ARTD family and is regulated by the aryl... 
TiPARP | 0419 | AHR
Dissertation
11/2012
The aryl hydrocarbon receptor (AHR) and estrogen receptor alpha (ERα) are ligand-activated transcription factors. Reciprocal crosstalk between these two... 
breast cancer | 0419 | AHR
Dissertation
The Journal of allergy and clinical immunology, ISSN 0091-6749, 8/2018, Volume 142, Issue 2, pp. 706 - 709.e4
Journal Article
Expert Opinion on Drug Metabolism & Toxicology, ISSN 1742-5255, 03/2019, Volume 15, Issue 3, pp. 219 - 229
Journal Article
1966, Forschungen zur deutschen Landeskunde, Volume Bd. 160, 128,12
Book
Seminars in cancer biology, ISSN 1044-579X, 05/2019
Glioblastoma (GBM) is an aggressive and incurable brain tumor; its malignancy has been associated with the activity of tumor infiltrating myeloid cells.... 
Journal Article
Journal of Endocrinological Investigation, ISSN 0391-4097, 07/2019, Volume 42, Issue 7, pp. 825 - 831
PurposeBiomarkers of clinical and therapeutic outcome in acromegaly are needed. Polymorphisms or epigenetic changes of detoxification genes, such as those... 
GSTP1 methylation | Acromegaly | AHR | Pituitary tumor | GSTP1 | AHR rs2066853 | ARYL-HYDROCARBON RECEPTOR | ENDOCRINOLOGY & METABOLISM | AIP | RISK | CANCER
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 06/2016, Volume 300, pp. 13 - 24
Obesity is an increasingly urgent global problem, yet, little is known about its causes and less is known how obesity can be effectively treated. We showed... 
Aryl hydrocarbon receptor | Obesity | TLR2/TGFβ/PI3K/NF-κB/IDO1/AHR axis | α-Naphthoflavone and CH-223191 | Liver steatosis | TOLL-LIKE-RECEPTORS | METABOLIC SYNDROME | DENDRITIC CELLS | INDOLEAMINE 2,3-DIOXYGENASE | LOW-DENSITY-LIPOPROTEIN | DIOXIN RECEPTOR | TLR2/TGF beta/PI3K/NF-kappa B/IDO1/AHR axis | alpha-Naphthoflavone and CH-223191 | REGULATORY T-CELLS | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | TOXICOLOGY | NF-KAPPA-B | ADIPOSE-TISSUE | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Receptors, Aryl Hydrocarbon - antagonists & inhibitors | Signal Transduction | Kynurenine - biosynthesis | Mice, Inbred C57BL | Fatty Liver - prevention & control | Male | Toll-Like Receptor 2 - metabolism | Animals | Adiposity | Benzoflavones - pharmacology | Lipids - blood | Obesity - prevention & control | Intra-Abdominal Fat - drug effects | Mice | Azo Compounds - pharmacology | Diet, Western | Transforming Growth Factor beta - metabolism | Hepatocytes - drug effects | Lipoproteins, LDL | Pyrazoles - pharmacology | Index Medicus | KYNURENINE | TRYPTOPHAN | METABOLITES | QUINOLINES | 60 APPLIED LIFE SCIENCES | LUCIFERASE | GROWTH FACTORS | HYDROXY COMPOUNDS | INHIBITION | DIET | LIGANDS | METABOLISM | LIVER | LIVER CELLS | MICE | METABOLIC DISEASES | RECEPTORS | LIPOPROTEINS | Aryl Hydrocarbon Receptor | NF-κB | PI3K | TGFβ | AHR axis | TLR2 | IDO1
Journal Article
Biochemical Journal, ISSN 0264-6021, 11/2005, Volume 392, Issue 1, pp. 153 - 161
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 11/2019, Volume 169, p. 113620
Aryl hydrocarbon receptor (AHR), identified in studies of dioxin toxicity, has been characterized as ligand-activated transcription factor involved in diverse... 
NASH | AHR, CD38, NAD metabolism | Hepatic steatosis
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 12/2019, Volume 134, p. 110803
Polychlorinated biphenyls (PCBs) would do serious damage to multiple systems, while coplanar polychlorinated biphenyls, the most toxic member of the family,... 
AhR | Cytokines | Oxidative damage | Polychlorinated biphenyl | Immunotoxicity | Apoptosis
Journal Article
TOXICOLOGICAL SCIENCES, ISSN 1096-6080, 01/2014, Volume 137, Issue 1, pp. 114 - 124
The contribution of environmental pollutants to liver fibrosis is an important and poorly explored issue. In vitro studies suggest that the environmental... 
SPRAGUE-DAWLEY RATS | TUMOR PROGRESSION | RECEPTOR AHR | AhR | PARAOXONASE-1 GENE-EXPRESSION | mice | EPITHELIAL-MESENCHYMAL TRANSITION | GROWTH-FACTOR-BETA | CIGARETTE-SMOKING | dioxin | HEPATIC STELLATE CELLS | inflammation | liver diseases | TOXICOLOGY | DEPENDENT MECHANISM | MOLECULAR-MECHANISMS
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 07/2019, Volume 294, Issue 29, pp. 11342 - 11353
The aryl hydrocarbon receptor (AhR) plays an important role in maintaining cellular homeostasis and also in pathophysiology. For example, the interplay between... 
PROMISCUITY | BIOCHEMISTRY & MOLECULAR BIOLOGY | aryl hydrocarbon receptor (AhR) | kynurenine | PROLIFERATION | nuclear transcription factor | 2,3,7,8-TETRACHLORODIBENZO-PARA-DIOXIN | AHR ACTIVATION | glioblastoma | gut microbiome | CARCINOGENESIS | INHIBITION | invasion | gene regulation | migration | tryptophan catabolism | LIGAND | tumor suppressor gene | CANCER CELL INVASION
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2014, Volume 5, p. 458
Journal Article
Chemosphere, ISSN 0045-6535, 2017, Volume 168, pp. 568 - 577
The upcoming energy structure optimization and the implementation of strict emissions control will effectively alleviated the pollution of... 
Environmental relevant level | Low molecular weighted PAHs | AhR binding | Macrophage
Journal Article
AMERICAN HISTORICAL REVIEW, ISSN 0002-8762, 06/2018, Volume 123, Issue 3, pp. 875 - 885
Journal Article
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